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The map label for this gene is cobH [H]

Identifier: 158314252

GI number: 158314252

Start: 2882885

End: 2883511

Strand: Direct

Name: cobH [H]

Synonym: Franean1_2422

Alternate gene names: 158314252

Gene position: 2882885-2883511 (Clockwise)

Preceding gene: 158314242

Following gene: 158314253

Centisome position: 32.1

GC content: 75.44

Gene sequence:

>627_bases
ATGACCGGCTACCTGCGCGACGCCGACGAGATCTACCGCCAGTCGTTCGCGACGATCCGCGCCGAGGCGGACCTGACCGG
CCTGCCCGCCGACCTCGCCCACGTCGTCGTACGCATGATCCACTCCTGCGGGATGGTCGATCTCGTCCGTGACATCGCGT
TCTCTCCCGAGGTGGCCGCCGCGGCGCGGGCCGCACTCGTCGGCGGCGCGCCGGTGCTCTGCGACACGGCGATGGTCGCC
GCCGGGGTGATCCGCCGCCGGCTGCCCGCGGACAACCCCGTCATCTGCACGCTCTCGGACCCGCGGGTCCCGGAGCTCGC
CCGGCACTCGGGAACCACCCGCACCGCCGCCGCGGTGGAGCTGTGGCGCGGCCGCCTCGACGGTGCGGTGGTCGTCGTCG
GCAACGCCCCGACCGCGCTGTTCCGCCTGCTCGAACTGGTCGAGGACGGAGCCGGCCGGCCGGCCGCCGTCGTCGGGGTG
CCGGTCGGTTTCGTCGGAGCGGCGGAGTCCAAGCAGGCCCTGGCCGCCCACCCGAGCGGGCTTGAGTACCTCGTGGTGCA
GGGCCGGCGCGGCGGCAGCGCGATGGCCGCGGCGGCCGTGAACGCCCTCGCCCGCGACGCGGACTGA

Upstream 100 bases:

>100_bases
GAACCCTCGCGCAGGCCGCCGCCGGGTCGGGTGCGCACGGCGACGTGCCCACATATGCTCCGCGGGTGCTCGCCCGTCCG
ACCTGCCTGGTCTCCGCCCG

Downstream 100 bases:

>100_bases
CCGGACCGGTGGAGACGGAACCGGCCCCTGATCCGGTACCGGGGGCGGAAGGCGCGCCCACGCCCGCATCCGCGCCGGGA
CTGGAACCGCGAGGTGCGTC

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: HBA synthase; Precorrin isomerase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTGYLRDADEIYRQSFATIRAEADLTGLPADLAHVVVRMIHSCGMVDLVRDIAFSPEVAAAARAALVGGAPVLCDTAMVA
AGVIRRRLPADNPVICTLSDPRVPELARHSGTTRTAAAVELWRGRLDGAVVVVGNAPTALFRLLELVEDGAGRPAAVVGV
PVGFVGAAESKQALAAHPSGLEYLVVQGRRGGSAMAAAAVNALARDAD

Sequences:

>Translated_208_residues
MTGYLRDADEIYRQSFATIRAEADLTGLPADLAHVVVRMIHSCGMVDLVRDIAFSPEVAAAARAALVGGAPVLCDTAMVA
AGVIRRRLPADNPVICTLSDPRVPELARHSGTTRTAAAVELWRGRLDGAVVVVGNAPTALFRLLELVEDGAGRPAAVVGV
PVGFVGAAESKQALAAHPSGLEYLVVQGRRGGSAMAAAAVNALARDAD
>Mature_207_residues
TGYLRDADEIYRQSFATIRAEADLTGLPADLAHVVVRMIHSCGMVDLVRDIAFSPEVAAAARAALVGGAPVLCDTAMVAA
GVIRRRLPADNPVICTLSDPRVPELARHSGTTRTAAAVELWRGRLDGAVVVVGNAPTALFRLLELVEDGAGRPAAVVGVP
VGFVGAAESKQALAAHPSGLEYLVVQGRRGGSAMAAAAVNALARDAD

Specific function: Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: =5.4.1.2 [H]

Molecular weight: Translated: 21470; Mature: 21339

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGYLRDADEIYRQSFATIRAEADLTGLPADLAHVVVRMIHSCGMVDLVRDIAFSPEVAA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHH
AARAALVGGAPVLCDTAMVAAGVIRRRLPADNPVICTLSDPRVPELARHSGTTRTAAAVE
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHH
LWRGRLDGAVVVVGNAPTALFRLLELVEDGAGRPAAVVGVPVGFVGAAESKQALAAHPSG
HHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHCCCCC
LEYLVVQGRRGGSAMAAAAVNALARDAD
CEEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TGYLRDADEIYRQSFATIRAEADLTGLPADLAHVVVRMIHSCGMVDLVRDIAFSPEVAA
CCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHH
AARAALVGGAPVLCDTAMVAAGVIRRRLPADNPVICTLSDPRVPELARHSGTTRTAAAVE
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHH
LWRGRLDGAVVVVGNAPTALFRLLELVEDGAGRPAAVVGVPVGFVGAAESKQALAAHPSG
HHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHCCCCC
LEYLVVQGRRGGSAMAAAAVNALARDAD
CEEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732194 [H]