Click here to switch to the map view.

The map label for this gene is degU [H]

Identifier: 158314132

GI number: 158314132

Start: 2749435

End: 2750163

Strand: Direct

Name: degU [H]

Synonym: Franean1_2299

Alternate gene names: 158314132

Gene position: 2749435-2750163 (Clockwise)

Preceding gene: 158314131

Following gene: 158314133

Centisome position: 30.61

GC content: 75.17

Gene sequence:

>729_bases
ATGATCGCGGAGGACTCCGTGCTGCTGCGGGAGGGGCTGACCAGGCTCCTCGAGGAGGACGGCTGCACCGTCACCGCCGC
GGTCGGGGACGGCGAGAGCCTGCTGCGGGCGGTCGCCCGGATCCAGCCGCAGGTGTGCGTCGTCGACGTCCGCCTGCCGC
CGACCTTCACCGACGAGGGCATCCGCGCCGCGCTCGTCCTGCGCCGGCAGTGGCCGGACGTCGCGGTGCTCGTGCTGTCC
CAGTACGTCGAGGAGCGCTACGCCGTCGACCTGATCGCCGGGCAGGCGCGGGGAGTCGGCTACCTGCTCAAGGACCGGGT
CTCCGACGTCGCCGACTTCCGCGAGGCGCTGCACCGGATCGCCGCCGGCGGCACCGTGCTCGACCCGGAGGTCGTCACCC
AGCTGTTGCTCCGCTCGCGCCGGCGGGACCCGCTCGCCAGCCTGACCAGACGGGAGTCCGAGGTGCTGGCGCTCATGGCG
CAGGGCCGGTCGAACACCGCGATCGCGGCCGCGATCGCGGTCACCGAACGGGCGGTCGAGAAGCACGTGACTGGCATCTT
CACCAAGTTCGGCCTGGCCCCGGCCGAGGACGACCACCGTCGCGTGCTCGCCGTCCTGCGCTTCCTGGACTCCGCCGCCG
CCGGCGGAGTCGGTGGCGGCGGCGCCCGCGGCGAGCGGCCGGCCCGTCCGGCGGGCGCGCGGGCGAGCGCGGGGCGCGGC
GATGTCTGA

Upstream 100 bases:

>100_bases
AGCCCGCCCGGTGGCGGGACGACCCTGCGGATGGAGCTGCCATGCGGGGACGCGACATGACCGGGGCCGGCCGGCCCGGG
GCGGTGACCCGGTGAATATC

Downstream 100 bases:

>100_bases
GCCGGGCCGGCGGGCCGCGCTCGCCGTCGGCGCGCTGCTCGCCGTCGTGGGCACCGCGGTCTGCGGCGTGCAGACCGTCG
ACGAGACGTCCGGCGAGGTG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MIAEDSVLLREGLTRLLEEDGCTVTAAVGDGESLLRAVARIQPQVCVVDVRLPPTFTDEGIRAALVLRRQWPDVAVLVLS
QYVEERYAVDLIAGQARGVGYLLKDRVSDVADFREALHRIAAGGTVLDPEVVTQLLLRSRRRDPLASLTRRESEVLALMA
QGRSNTAIAAAIAVTERAVEKHVTGIFTKFGLAPAEDDHRRVLAVLRFLDSAAAGGVGGGGARGERPARPAGARASAGRG
DV

Sequences:

>Translated_242_residues
MIAEDSVLLREGLTRLLEEDGCTVTAAVGDGESLLRAVARIQPQVCVVDVRLPPTFTDEGIRAALVLRRQWPDVAVLVLS
QYVEERYAVDLIAGQARGVGYLLKDRVSDVADFREALHRIAAGGTVLDPEVVTQLLLRSRRRDPLASLTRRESEVLALMA
QGRSNTAIAAAIAVTERAVEKHVTGIFTKFGLAPAEDDHRRVLAVLRFLDSAAAGGVGGGGARGERPARPAGARASAGRG
DV
>Mature_242_residues
MIAEDSVLLREGLTRLLEEDGCTVTAAVGDGESLLRAVARIQPQVCVVDVRLPPTFTDEGIRAALVLRRQWPDVAVLVLS
QYVEERYAVDLIAGQARGVGYLLKDRVSDVADFREALHRIAAGGTVLDPEVVTQLLLRSRRRDPLASLTRRESEVLALMA
QGRSNTAIAAAIAVTERAVEKHVTGIFTKFGLAPAEDDHRRVLAVLRFLDSAAAGGVGGGGARGERPARPAGARASAGRG
DV

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=215, Percent_Identity=33.0232558139535, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790102, Length=204, Percent_Identity=28.4313725490196, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25821; Mature: 25821

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAEDSVLLREGLTRLLEEDGCTVTAAVGDGESLLRAVARIQPQVCVVDVRLPPTFTDEG
CCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCH
IRAALVLRRQWPDVAVLVLSQYVEERYAVDLIAGQARGVGYLLKDRVSDVADFREALHRI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAGGTVLDPEVVTQLLLRSRRRDPLASLTRRESEVLALMAQGRSNTAIAAAIAVTERAVE
HCCCCEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
KHVTGIFTKFGLAPAEDDHRRVLAVLRFLDSAAAGGVGGGGARGERPARPAGARASAGRG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DV
CC
>Mature Secondary Structure
MIAEDSVLLREGLTRLLEEDGCTVTAAVGDGESLLRAVARIQPQVCVVDVRLPPTFTDEG
CCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCH
IRAALVLRRQWPDVAVLVLSQYVEERYAVDLIAGQARGVGYLLKDRVSDVADFREALHRI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAGGTVLDPEVVTQLLLRSRRRDPLASLTRRESEVLALMAQGRSNTAIAAAIAVTERAVE
HCCCCEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
KHVTGIFTKFGLAPAEDDHRRVLAVLRFLDSAAAGGVGGGGARGERPARPAGARASAGRG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]