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The map label for this gene is uppS1 [H]

Identifier: 158313953

GI number: 158313953

Start: 2544673

End: 2545674

Strand: Direct

Name: uppS1 [H]

Synonym: Franean1_2119

Alternate gene names: 158313953

Gene position: 2544673-2545674 (Clockwise)

Preceding gene: 158313952

Following gene: 158313954

Centisome position: 28.33

GC content: 72.36

Gene sequence:

>1002_bases
GTGGCCGAGGGCGGGGGCCCTGGCCGGGCACGGCAGTGCGCGGCGGGCGTGAGGGGACCGTGTGAGGAGCGGGGACGGGA
TGTGTGCTGCGAGACCGGCGGTCCGGGTGTGCGCGGGCCGGCCGGTTCGGACCATGGGGGTGAGCGCCCCACCGGGGCGG
GGGTCGGTCGCCGTGCCGTCGGCCCGAACGAGAGGATGTCGGCTGTGAGCCTGCGTGAAGAGGTGGGCCGGCGGTTCCGC
GATCCGCGTCCTCATCCGTCCGGAGCGCAGCCACCGCCGTTGCCGCGGGCCCTGGTCCCGCAGCATGTCGGGATCGTCAT
GGACGGAAACGGGCGCTGGGCGAAGCTGCGCGGCCTGCCCCGTACCAAGGGGCACGAGGCGGGTGAGGAGGCGCTGTTCG
ACTGCGTCGAGGGCGCCATCGAGATGGGGGTGCGCTGGCTGTCGGTGTACGCGTTCTCCACGGAGAACTGGAAGCGCTCG
CCGGACGAGGTCGCGTTCCTGATGCGGTTCACCGACGGCGTGTTCGGTCGCCGTATCGACGACATGGACGAGCTCGGAGT
CCGGGTCCGCTGGGCGGGCCGCCGTCCCCGGCTGTGGGGCAACGTGATCCGGCGGCTGGAGTCGGCGGAGCAGCGCACCC
GGGACAACGACCGGCTCACGCTCGTGATGTGCGTGAACTACGGCGGGCGGGCCGAGCTGGCGGACGCCGCGGCGGCGATC
GCCCGGGACGTGCGGGCCGGCCTGCTGCGCCCGGAGCGCGTCAACGAGGAGACCGTCGCCCGGTATCTCGACGAGCCCGA
CATGCCGGACGTCGACCTGCTCATCCGGACGTCCGGCGAGCAGCGGCTGAGTAACTTCCTGCTCTGGCAGGCCGCGTACG
CCGAGTTCTCCTTCGTGCCCACTCTGTGGCCTGACTTCGACCGCCGGGATCTGTGGCTGGCCTGTGAGGAGTACGCCCGT
CGTGACCGGCGCTACGGCGGGATCATCACCAACCGTGCCTGA

Upstream 100 bases:

>100_bases
CGTGGCCGCCTACCTGCAGTGGCATCTCGAGCGGGCGCTGCGCGCCCTTCCGCATCTCGAACGGACGTGAGGGCCACGGG
CATGGGCGGCCGGAGGACAC

Downstream 100 bases:

>100_bases
CCGCGACCAGACGGGGGCTCCGGTGGTGGCGGTCCTGCGCTTCGAGGTGCCCGCGCCGGCCCAGGTCGGCTTCGCGGCGG
CCGGGGAGCGGGTGGTGGCG

Product: undecaprenyl diphosphate synthase

Products: NA

Alternate protein names: UPP synthase 1; Di-trans,poly-cis-decaprenylcistransferase 1; Undecaprenyl diphosphate synthase 1; UDS 1 [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAEGGGPGRARQCAAGVRGPCEERGRDVCCETGGPGVRGPAGSDHGGERPTGAGVGRRAVGPNERMSAVSLREEVGRRFR
DPRPHPSGAQPPPLPRALVPQHVGIVMDGNGRWAKLRGLPRTKGHEAGEEALFDCVEGAIEMGVRWLSVYAFSTENWKRS
PDEVAFLMRFTDGVFGRRIDDMDELGVRVRWAGRRPRLWGNVIRRLESAEQRTRDNDRLTLVMCVNYGGRAELADAAAAI
ARDVRAGLLRPERVNEETVARYLDEPDMPDVDLLIRTSGEQRLSNFLLWQAAYAEFSFVPTLWPDFDRRDLWLACEEYAR
RDRRYGGIITNRA

Sequences:

>Translated_333_residues
MAEGGGPGRARQCAAGVRGPCEERGRDVCCETGGPGVRGPAGSDHGGERPTGAGVGRRAVGPNERMSAVSLREEVGRRFR
DPRPHPSGAQPPPLPRALVPQHVGIVMDGNGRWAKLRGLPRTKGHEAGEEALFDCVEGAIEMGVRWLSVYAFSTENWKRS
PDEVAFLMRFTDGVFGRRIDDMDELGVRVRWAGRRPRLWGNVIRRLESAEQRTRDNDRLTLVMCVNYGGRAELADAAAAI
ARDVRAGLLRPERVNEETVARYLDEPDMPDVDLLIRTSGEQRLSNFLLWQAAYAEFSFVPTLWPDFDRRDLWLACEEYAR
RDRRYGGIITNRA
>Mature_332_residues
AEGGGPGRARQCAAGVRGPCEERGRDVCCETGGPGVRGPAGSDHGGERPTGAGVGRRAVGPNERMSAVSLREEVGRRFRD
PRPHPSGAQPPPLPRALVPQHVGIVMDGNGRWAKLRGLPRTKGHEAGEEALFDCVEGAIEMGVRWLSVYAFSTENWKRSP
DEVAFLMRFTDGVFGRRIDDMDELGVRVRWAGRRPRLWGNVIRRLESAEQRTRDNDRLTLVMCVNYGGRAELADAAAAIA
RDVRAGLLRPERVNEETVARYLDEPDMPDVDLLIRTSGEQRLSNFLLWQAAYAEFSFVPTLWPDFDRRDLWLACEEYARR
DRRYGGIITNRA

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580742, Length=223, Percent_Identity=34.9775784753363, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI45580738, Length=223, Percent_Identity=34.9775784753363, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1786371, Length=226, Percent_Identity=41.1504424778761, Blast_Score=183, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71993029, Length=227, Percent_Identity=37.4449339207048, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6319474, Length=214, Percent_Identity=36.9158878504673, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323748, Length=231, Percent_Identity=33.7662337662338, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18857969, Length=209, Percent_Identity=35.8851674641148, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 37120; Mature: 36989

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGGGPGRARQCAAGVRGPCEERGRDVCCETGGPGVRGPAGSDHGGERPTGAGVGRRAV
CCCCCCCCHHHHHHHCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPNERMSAVSLREEVGRRFRDPRPHPSGAQPPPLPRALVPQHVGIVMDGNGRWAKLRGLP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEECCCCCEEEECCCC
RTKGHEAGEEALFDCVEGAIEMGVRWLSVYAFSTENWKRSPDEVAFLMRFTDGVFGRRID
CCCCCCCHHHHHHHHHHHHHHHHHHEEHEEEEECCCCCCCHHHHHHHHHHHCCHHHCCCC
DMDELGVRVRWAGRRPRLWGNVIRRLESAEQRTRDNDRLTLVMCVNYGGRAELADAAAAI
CHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHH
ARDVRAGLLRPERVNEETVARYLDEPDMPDVDLLIRTSGEQRLSNFLLWQAAYAEFSFVP
HHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCC
TLWPDFDRRDLWLACEEYARRDRRYGGIITNRA
CCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure 
AEGGGPGRARQCAAGVRGPCEERGRDVCCETGGPGVRGPAGSDHGGERPTGAGVGRRAV
CCCCCCCHHHHHHHCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPNERMSAVSLREEVGRRFRDPRPHPSGAQPPPLPRALVPQHVGIVMDGNGRWAKLRGLP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEECCCCCEEEECCCC
RTKGHEAGEEALFDCVEGAIEMGVRWLSVYAFSTENWKRSPDEVAFLMRFTDGVFGRRID
CCCCCCCHHHHHHHHHHHHHHHHHHEEHEEEEECCCCCCCHHHHHHHHHHHCCHHHCCCC
DMDELGVRVRWAGRRPRLWGNVIRRLESAEQRTRDNDRLTLVMCVNYGGRAELADAAAAI
CHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHH
ARDVRAGLLRPERVNEETVARYLDEPDMPDVDLLIRTSGEQRLSNFLLWQAAYAEFSFVP
HHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCC
TLWPDFDRRDLWLACEEYARRDRRYGGIITNRA
CCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]