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The map label for this gene is yciK [C]

Identifier: 158313867

GI number: 158313867

Start: 2441642

End: 2442952

Strand: Direct

Name: yciK [C]

Synonym: Franean1_2032

Alternate gene names: 158313867

Gene position: 2441642-2442952 (Clockwise)

Preceding gene: 158313866

Following gene: 158313870

Centisome position: 27.18

GC content: 74.29

Gene sequence:

>1311_bases
ATGCGGCCCGGCGCCCGGGACGCGGGCTGGAGCCTGGCCGACGTGCCGGACCAGCGGGGACGGACCGCCGTCGTCACCGG
TGCGAACAGCGGCATCGGCTTCGAGGCGGCGAAGGCGCTCGCCGAGCGCGGCGCGACCGTCGTCCTGGCCTGCCGCGAGC
CGGCCCGGGCCGAGCAGGCCGCCGCACGCATCCGGGCCGCCGCGCCGCGGGCGGACGTCCACGTCGAGCCGCTCGACCTG
ATCTCGATGACCTCCGTGCGCGCGGCCGCCGAACGGATCCGGGCCGCCCACCCGCGGCTCGACCTGCTCGTCAACAACGC
CGGGGTGATGCTGCCGTCGCCCGGTCCCGGCGGTGCCGCCCTCGGTGCCGGCTTTGGTGACGACGGCCTCGGTGATCACG
GCATCGAGCCGACGTTCGGGGTCAACCACCTGGGGCACTTCGCGCTGACGGGCCTCCTGCTCGACCGCCTTCTGGCGACG
CCGCACTCGCGGATCGTGACGGTCAGCAGCCTCGCCCACCTCGTCGGCCGCCTCGACCTCGAGCAGCTGCGCCGCCTCCC
GCCGCACGCCGACCGACCGGGGGGCAGCCCGCCCGTGGTCGTGCCCGACCAGCGTGCCGGGTCGCCGTCCGAACCACCCC
TGGCGTCGCCGGCCCGCCAGCGTTCACAGCGGAGGTCAGAAACACAGCGGAGGTCAGAAACACAGCGGAGGTCAGAAACA
CAGCGGGGGTCAGGAACACCGCGCGCGCAGGGCATGCAGCGCCTCCAGAGTCTTCAGGGCACGCGGGGCCCGCAGAGCCG
GCGGCTGCCCCGGCAGCGCCTGCCGTATCCGACATCCAAGCTGGCGAACCTGATGTTCACCTTCGAGCTGCAGCGCCGGC
TCGCGGCCACCGGAGCGTCGACGATCGCGGTGGCCGCGCACCCGGGCATCGCCCGCACGGGGCTCACCCGCAACCTCATG
CCCCCGGCGCGGGTGTTCATGGGCCAGCGACTGGCACCGCTGATGTCGTGGCTGGTCCAGGAGCCGGAGATCGGCGCGCT
CGCCACCGTCCGGGCCGCCCTCGACCCGGCGGTGCACGCCGGTGAGTACTACGGACCGTCAGGGCTCTTCCGCAGCACCG
GTCCGCCCGCTGTCGGGCGATCCAGCGCCCGCTCGCGCGACGCCCGCCAGCAGCAGCGGCTGTGGGCGGAGTCCGAGCGG
CTCACCGGCGTCACTTACGACTTCGATCCCTCCTCGGGGACAGGGCCCGGCGGTGTCGGATCCTGGAGGAACAACGGGAG
AAGCGCGTCGCGGAGCGCGGAACTGACCTGA

Upstream 100 bases:

>100_bases
AGCGGCTGTGGCCCCGCGTGGTGGCGGACAGCCGCTGGTACAAGAGCTATCAGGCCAAGTCGAAGCGGGTGATCCCGCTC
GTCCTGCTCGAGCCGCGCTG

Downstream 100 bases:

>100_bases
CGGATCTGGTCGTGCACCGCTACCAGATCGTCCAGCGAACCTGCCGCCGAGCCGATGCGGCCCTGCTGGTGACGGTCCGG
AAGGACGAGGGGAAGCCCAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MRPGARDAGWSLADVPDQRGRTAVVTGANSGIGFEAAKALAERGATVVLACREPARAEQAAARIRAAAPRADVHVEPLDL
ISMTSVRAAAERIRAAHPRLDLLVNNAGVMLPSPGPGGAALGAGFGDDGLGDHGIEPTFGVNHLGHFALTGLLLDRLLAT
PHSRIVTVSSLAHLVGRLDLEQLRRLPPHADRPGGSPPVVVPDQRAGSPSEPPLASPARQRSQRRSETQRRSETQRRSET
QRGSGTPRAQGMQRLQSLQGTRGPQSRRLPRQRLPYPTSKLANLMFTFELQRRLAATGASTIAVAAHPGIARTGLTRNLM
PPARVFMGQRLAPLMSWLVQEPEIGALATVRAALDPAVHAGEYYGPSGLFRSTGPPAVGRSSARSRDARQQQRLWAESER
LTGVTYDFDPSSGTGPGGVGSWRNNGRSASRSAELT

Sequences:

>Translated_436_residues
MRPGARDAGWSLADVPDQRGRTAVVTGANSGIGFEAAKALAERGATVVLACREPARAEQAAARIRAAAPRADVHVEPLDL
ISMTSVRAAAERIRAAHPRLDLLVNNAGVMLPSPGPGGAALGAGFGDDGLGDHGIEPTFGVNHLGHFALTGLLLDRLLAT
PHSRIVTVSSLAHLVGRLDLEQLRRLPPHADRPGGSPPVVVPDQRAGSPSEPPLASPARQRSQRRSETQRRSETQRRSET
QRGSGTPRAQGMQRLQSLQGTRGPQSRRLPRQRLPYPTSKLANLMFTFELQRRLAATGASTIAVAAHPGIARTGLTRNLM
PPARVFMGQRLAPLMSWLVQEPEIGALATVRAALDPAVHAGEYYGPSGLFRSTGPPAVGRSSARSRDARQQQRLWAESER
LTGVTYDFDPSSGTGPGGVGSWRNNGRSASRSAELT
>Mature_436_residues
MRPGARDAGWSLADVPDQRGRTAVVTGANSGIGFEAAKALAERGATVVLACREPARAEQAAARIRAAAPRADVHVEPLDL
ISMTSVRAAAERIRAAHPRLDLLVNNAGVMLPSPGPGGAALGAGFGDDGLGDHGIEPTFGVNHLGHFALTGLLLDRLLAT
PHSRIVTVSSLAHLVGRLDLEQLRRLPPHADRPGGSPPVVVPDQRAGSPSEPPLASPARQRSQRRSETQRRSETQRRSET
QRGSGTPRAQGMQRLQSLQGTRGPQSRRLPRQRLPYPTSKLANLMFTFELQRRLAATGASTIAVAAHPGIARTGLTRNLM
PPARVFMGQRLAPLMSWLVQEPEIGALATVRAALDPAVHAGEYYGPSGLFRSTGPPAVGRSSARSRDARQQQRLWAESER
LTGVTYDFDPSSGTGPGGVGSWRNNGRSASRSAELT

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706523, Length=174, Percent_Identity=42.5287356321839, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI225579078, Length=166, Percent_Identity=43.9759036144578, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI166795268, Length=165, Percent_Identity=45.4545454545455, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI186928839, Length=165, Percent_Identity=44.2424242424242, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI146231950, Length=169, Percent_Identity=44.9704142011834, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI10190746, Length=178, Percent_Identity=38.7640449438202, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI193804850, Length=177, Percent_Identity=37.2881355932203, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI19923931, Length=128, Percent_Identity=42.1875, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17558006, Length=157, Percent_Identity=35.6687898089172, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17532805, Length=180, Percent_Identity=35.5555555555556, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17532791, Length=154, Percent_Identity=37.012987012987, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32565532, Length=150, Percent_Identity=36.6666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193207620, Length=154, Percent_Identity=33.7662337662338, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17505416, Length=163, Percent_Identity=29.4478527607362, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71992402, Length=154, Percent_Identity=35.0649350649351, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI72001364, Length=159, Percent_Identity=35.8490566037736, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI45554248, Length=164, Percent_Identity=47.5609756097561, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24640117, Length=164, Percent_Identity=47.5609756097561, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28573296, Length=167, Percent_Identity=40.7185628742515, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI22024069, Length=169, Percent_Identity=41.4201183431953, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19921754, Length=168, Percent_Identity=40.4761904761905, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI20129347, Length=169, Percent_Identity=39.6449704142012, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45553409, Length=167, Percent_Identity=36.5269461077844, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647948, Length=167, Percent_Identity=36.5269461077844, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647946, Length=167, Percent_Identity=36.5269461077844, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24586328, Length=164, Percent_Identity=39.6341463414634, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI161076371, Length=167, Percent_Identity=37.125748502994, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24656154, Length=172, Percent_Identity=37.7906976744186, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19922628, Length=172, Percent_Identity=37.7906976744186, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647931, Length=179, Percent_Identity=35.7541899441341, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 46344; Mature: 46344

Theoretical pI: Translated: 11.96; Mature: 11.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPGARDAGWSLADVPDQRGRTAVVTGANSGIGFEAAKALAERGATVVLACREPARAEQA
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHH
AARIRAAAPRADVHVEPLDLISMTSVRAAAERIRAAHPRLDLLVNNAGVMLPSPGPGGAA
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHH
LGAGFGDDGLGDHGIEPTFGVNHLGHFALTGLLLDRLLATPHSRIVTVSSLAHLVGRLDL
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHCCCH
EQLRRLPPHADRPGGSPPVVVPDQRAGSPSEPPLASPARQRSQRRSETQRRSETQRRSET
HHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRGSGTPRAQGMQRLQSLQGTRGPQSRRLPRQRLPYPTSKLANLMFTFELQRRLAATGAS
HCCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
TIAVAAHPGIARTGLTRNLMPPARVFMGQRLAPLMSWLVQEPEIGALATVRAALDPAVHA
EEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GEYYGPSGLFRSTGPPAVGRSSARSRDARQQQRLWAESERLTGVTYDFDPSSGTGPGGVG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCC
SWRNNGRSASRSAELT
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPGARDAGWSLADVPDQRGRTAVVTGANSGIGFEAAKALAERGATVVLACREPARAEQA
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHH
AARIRAAAPRADVHVEPLDLISMTSVRAAAERIRAAHPRLDLLVNNAGVMLPSPGPGGAA
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHH
LGAGFGDDGLGDHGIEPTFGVNHLGHFALTGLLLDRLLATPHSRIVTVSSLAHLVGRLDL
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHCCCH
EQLRRLPPHADRPGGSPPVVVPDQRAGSPSEPPLASPARQRSQRRSETQRRSETQRRSET
HHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRGSGTPRAQGMQRLQSLQGTRGPQSRRLPRQRLPYPTSKLANLMFTFELQRRLAATGAS
HCCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
TIAVAAHPGIARTGLTRNLMPPARVFMGQRLAPLMSWLVQEPEIGALATVRAALDPAVHA
EEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GEYYGPSGLFRSTGPPAVGRSSARSRDARQQQRLWAESERLTGVTYDFDPSSGTGPGGVG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCC
SWRNNGRSASRSAELT
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]