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The map label for this gene is thiO [H]

Identifier: 158313714

GI number: 158313714

Start: 2256400

End: 2257539

Strand: Direct

Name: thiO [H]

Synonym: Franean1_1878

Alternate gene names: 158313714

Gene position: 2256400-2257539 (Clockwise)

Preceding gene: 158313713

Following gene: 158313715

Centisome position: 25.12

GC content: 73.07

Gene sequence:

>1140_bases
ATGGCTGAGAACGTGGTCGTCATCGGTGCCGGTGCCTACGGCGCGGCGGTCGCCGCCTCGCTGGCGCGCCGCGGTGCCCG
GGTCGTCATCGTGGAGGCCGGCGCTCCCGCGGGCGGCACCTCCGGCGCGACGTTCGCCTGGATCAACGCCTCCAGCAAGC
AGTCACACCCGTACCACGCTTTCGGGGTCGCGGCGATGGACGCCCACCGCAGGCTGGCGGCCGAGACGCCCGCCGGCGAC
TGGTACCACGAGTCCGGCAACCTACAGTGGGAGACCGCCGATGCCGAGCACGAGGTGCTGCGCCGGAAGGTCGCCACCGT
CGTCGCCTACGGGTACGAGGTGCGCTGGCTCAGCCGGGCCGAGGCGCTGAAGCTCGAACCGGACGTGGATCCCGCCGCGC
TTCCGGCGGACGAGATCGCCTACTTCCCGCGGGAGGGGTGGGTCGAGCCGGCCCGCCTGGTCGGCCACCTGCTCTCGAGG
GCGGTGTCCCGGGGCGCCGAGCTGGTGACCGACGACCCGGTCGTCAGCCTGCGGATCGCCGCTGGACTGGTACGTGCCGT
GGGCCTCGCCTCGGGTCGCTCGATCTCCGCGGGCGCGGTCGTGAACTGCGCGGGGCCGCGCGCCGGCGCGATCGCCGTGC
TCGCCGGCCTGGATCTGCCGATGCGCAACACCCACGGCGTGCTCGTCCACACCTCCCCGGTCACCGTCTCGGCATCCCGC
GTCATCCACGCGCCGGACGTCCACCTGCGGCCGGACGGGGGCGGACGGCTGCTGCTGCACACCCAGGCGATCGACGGCGC
GGTGCGTATTTCCGGCAACGGTGAAATGAGCGCGGACGGATCGGCGGTCGAGACGATCCTCGAGGCGAGCCGGGTGCTCT
ACCCGGGAATCCGGGCGGCGACGGTGGAGAAGGTCCGGATCGGTGAACGGCCCATTCCCGGGGACGGCCTACCCGTGCTG
GGGCGGGCGGTCGAGCTGCCCAACTTCCATTTCGCCGTCTCGCACAGCGGTGTGACCCTGAGCGTGCACGCCGGTGACCT
GGTCGCGGCGGAGGTGATGGGGGAGGACCACAGCGACGAGCTCGCTGCCTTCCGGATCGAGCGGTTCCGGCCGGGCGGCC
CGGTGAGGGCGGCTCGGTGA

Upstream 100 bases:

>100_bases
CCGCGCGGGCATTGTGAGTCAGGGTGAAACTAGTTACTGAAACTAGTTTCAAGAGTGCGTGACGCGGCGAGAGCCGACGG
CCCGGAGGGAAAGGATCGGC

Downstream 100 bases:

>100_bases
AGGCAGGCGGCTGAGGCGGCTGAGGGGAGCGCCGGGGGAGGGCCGGTGCGGGGAAAGGCCTGTGGGGAGGAATGACGCGC
ACGGTCGTCCTGAACGGAGG

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: GO [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MAENVVVIGAGAYGAAVAASLARRGARVVIVEAGAPAGGTSGATFAWINASSKQSHPYHAFGVAAMDAHRRLAAETPAGD
WYHESGNLQWETADAEHEVLRRKVATVVAYGYEVRWLSRAEALKLEPDVDPAALPADEIAYFPREGWVEPARLVGHLLSR
AVSRGAELVTDDPVVSLRIAAGLVRAVGLASGRSISAGAVVNCAGPRAGAIAVLAGLDLPMRNTHGVLVHTSPVTVSASR
VIHAPDVHLRPDGGGRLLLHTQAIDGAVRISGNGEMSADGSAVETILEASRVLYPGIRAATVEKVRIGERPIPGDGLPVL
GRAVELPNFHFAVSHSGVTLSVHAGDLVAAEVMGEDHSDELAAFRIERFRPGGPVRAAR

Sequences:

>Translated_379_residues
MAENVVVIGAGAYGAAVAASLARRGARVVIVEAGAPAGGTSGATFAWINASSKQSHPYHAFGVAAMDAHRRLAAETPAGD
WYHESGNLQWETADAEHEVLRRKVATVVAYGYEVRWLSRAEALKLEPDVDPAALPADEIAYFPREGWVEPARLVGHLLSR
AVSRGAELVTDDPVVSLRIAAGLVRAVGLASGRSISAGAVVNCAGPRAGAIAVLAGLDLPMRNTHGVLVHTSPVTVSASR
VIHAPDVHLRPDGGGRLLLHTQAIDGAVRISGNGEMSADGSAVETILEASRVLYPGIRAATVEKVRIGERPIPGDGLPVL
GRAVELPNFHFAVSHSGVTLSVHAGDLVAAEVMGEDHSDELAAFRIERFRPGGPVRAAR
>Mature_378_residues
AENVVVIGAGAYGAAVAASLARRGARVVIVEAGAPAGGTSGATFAWINASSKQSHPYHAFGVAAMDAHRRLAAETPAGDW
YHESGNLQWETADAEHEVLRRKVATVVAYGYEVRWLSRAEALKLEPDVDPAALPADEIAYFPREGWVEPARLVGHLLSRA
VSRGAELVTDDPVVSLRIAAGLVRAVGLASGRSISAGAVVNCAGPRAGAIAVLAGLDLPMRNTHGVLVHTSPVTVSASRV
IHAPDVHLRPDGGGRLLLHTQAIDGAVRISGNGEMSADGSAVETILEASRVLYPGIRAATVEKVRIGERPIPGDGLPVLG
RAVELPNFHFAVSHSGVTLSVHAGDLVAAEVMGEDHSDELAAFRIERFRPGGPVRAAR

Specific function: Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha- keto acids, ammonia/amine, and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine), N-ethylglycine and glycine. Can also oxidize th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DAO family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=389, Percent_Identity=23.9074550128535, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21361378, Length=389, Percent_Identity=23.9074550128535, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.3.19 [H]

Molecular weight: Translated: 39529; Mature: 39398

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENVVVIGAGAYGAAVAASLARRGARVVIVEAGAPAGGTSGATFAWINASSKQSHPYHA
CCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEE
FGVAAMDAHRRLAAETPAGDWYHESGNLQWETADAEHEVLRRKVATVVAYGYEVRWLSRA
EEEEHHHHHHHHHCCCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCC
EALKLEPDVDPAALPADEIAYFPREGWVEPARLVGHLLSRAVSRGAELVTDDPVVSLRIA
CEEEECCCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEEHHHH
AGLVRAVGLASGRSISAGAVVNCAGPRAGAIAVLAGLDLPMRNTHGVLVHTSPVTVSASR
HHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEECCCEEEECCE
VIHAPDVHLRPDGGGRLLLHTQAIDGAVRISGNGEMSADGSAVETILEASRVLYPGIRAA
EEECCCCEECCCCCCEEEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCE
TVEKVRIGERPIPGDGLPVLGRAVELPNFHFAVSHSGVTLSVHAGDLVAAEVMGEDHSDE
EEEEEECCCCCCCCCCCCCCCCEEECCCEEEEEECCCEEEEEECCCEEEEEHHCCCCCCC
LAAFRIERFRPGGPVRAAR
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AENVVVIGAGAYGAAVAASLARRGARVVIVEAGAPAGGTSGATFAWINASSKQSHPYHA
CCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEE
FGVAAMDAHRRLAAETPAGDWYHESGNLQWETADAEHEVLRRKVATVVAYGYEVRWLSRA
EEEEHHHHHHHHHCCCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCC
EALKLEPDVDPAALPADEIAYFPREGWVEPARLVGHLLSRAVSRGAELVTDDPVVSLRIA
CEEEECCCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEEHHHH
AGLVRAVGLASGRSISAGAVVNCAGPRAGAIAVLAGLDLPMRNTHGVLVHTSPVTVSASR
HHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEECCCEEEECCE
VIHAPDVHLRPDGGGRLLLHTQAIDGAVRISGNGEMSADGSAVETILEASRVLYPGIRAA
EEECCCCEECCCCCCEEEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCE
TVEKVRIGERPIPGDGLPVLGRAVELPNFHFAVSHSGVTLSVHAGDLVAAEVMGEDHSDE
EEEEEECCCCCCCCCCCCCCCCEEECCCEEEEEECCCEEEEEECCCEEEEEHHCCCCCCC
LAAFRIERFRPGGPVRAAR
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9827558; 11744710 [H]