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The map label for this gene is pyrF [H]

Identifier: 158313547

GI number: 158313547

Start: 2046345

End: 2047184

Strand: Direct

Name: pyrF [H]

Synonym: Franean1_1711

Alternate gene names: 158313547

Gene position: 2046345-2047184 (Clockwise)

Preceding gene: 158313546

Following gene: 158313548

Centisome position: 22.78

GC content: 73.57

Gene sequence:

>840_bases
GTGACCTCATCGGGCGCCCCCCGCCGGTGGACGCCACCGGCGGGCCGCGCCCCGATCGCGGTCGCGCTCGACGCTCCGGA
CGCCGCCACCGCGCTGGGCTGGGCCCGCGAGGTGGCGCCGCACGTCGCCGTGCTGAAGATCGGTCTGGAGCTCTTCTACC
GGGCCGGGCCGACGATCGTGACTGCGCTGCGTGACGAAGGGCTGCTCGCTCCGGCTCGGCCGGCGGAGCCTGCGGCGCCT
GCTCGGGTGGTGAGTTCCGTCACGGGGGGTGATGTGACGGACGGCTGGGGTGAGTCGCACGGCTCCGCGGCGCCCGAGCT
CTTCCTCGACCTGAAGCTCCACGACATACCGGCGACCGTGGCCGGCGGGATGCGCTCGCTGGCCACGCTGGCACCTCGCT
TCGTGACCGTGCATGCGGCCGGCGGCGCGGCCATGGTGCGCGCCGCGGTCGACGCCGGGCCCGATGTTCATGTAACCGCG
GTCACGGTGCTGACGTCGCTGGACGCCGCCACGCTCGCCGCCGTCGGGCTGTCCGGACCGCCCTCGGACGCCGTCCGCAG
GCTCGCGGTGCTCGCTGTGGAGGCCGGTGCGCGGGCGCTCGTCTGCAGCCCGAAAGAGGTCTCCATGGTCCGCGCGGAGC
TTGGTGAAACTGTGACTCTGGTCACGCCTGGAGTGCGTCCAGAGGGGTCTGAGCGGGCTGACCAGGCCCGGGTCGCCACC
CCGGAACGGGCACTCGCTGACGGTTCGGACCTCCTCGTGATCGGCCGTCCGATCACCTCCGCGGCCGATCGGGCCGTGGC
CGCCGCCACTATCGCCACCAGGGTTACTCCACTCCGGTAG

Upstream 100 bases:

>100_bases
CGGGCTCCCGGGCGCCGGGGGCGCGGCCGGGACCCGCGCCGGGCGCCGGGTCGGGATCCGGCTCGGCCGGCGGGGCGCCC
GCCTCGACCGTGGCGGACCG

Downstream 100 bases:

>100_bases
GCCCTTGACCTGCGCAAACGCCACTACGGGTGGATCTGGGCCGCTCTGGGTGCCCGAGTACCGGTACGGTGGGGCCGCTA
CGGACCGAATGCGTCCGGCG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTSSGAPRRWTPPAGRAPIAVALDAPDAATALGWAREVAPHVAVLKIGLELFYRAGPTIVTALRDEGLLAPARPAEPAAP
ARVVSSVTGGDVTDGWGESHGSAAPELFLDLKLHDIPATVAGGMRSLATLAPRFVTVHAAGGAAMVRAAVDAGPDVHVTA
VTVLTSLDAATLAAVGLSGPPSDAVRRLAVLAVEAGARALVCSPKEVSMVRAELGETVTLVTPGVRPEGSERADQARVAT
PERALADGSDLLVIGRPITSAADRAVAAATIATRVTPLR

Sequences:

>Translated_279_residues
MTSSGAPRRWTPPAGRAPIAVALDAPDAATALGWAREVAPHVAVLKIGLELFYRAGPTIVTALRDEGLLAPARPAEPAAP
ARVVSSVTGGDVTDGWGESHGSAAPELFLDLKLHDIPATVAGGMRSLATLAPRFVTVHAAGGAAMVRAAVDAGPDVHVTA
VTVLTSLDAATLAAVGLSGPPSDAVRRLAVLAVEAGARALVCSPKEVSMVRAELGETVTLVTPGVRPEGSERADQARVAT
PERALADGSDLLVIGRPITSAADRAVAAATIATRVTPLR
>Mature_278_residues
TSSGAPRRWTPPAGRAPIAVALDAPDAATALGWAREVAPHVAVLKIGLELFYRAGPTIVTALRDEGLLAPARPAEPAAPA
RVVSSVTGGDVTDGWGESHGSAAPELFLDLKLHDIPATVAGGMRSLATLAPRFVTVHAAGGAAMVRAAVDAGPDVHVTAV
TVLTSLDAATLAAVGLSGPPSDAVRRLAVLAVEAGARALVCSPKEVSMVRAELGETVTLVTPGVRPEGSERADQARVATP
ERALADGSDLLVIGRPITSAADRAVAAATIATRVTPLR

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=268, Percent_Identity=36.1940298507463, Blast_Score=150, Evalue=6e-38,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 28210; Mature: 28078

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSGAPRRWTPPAGRAPIAVALDAPDAATALGWAREVAPHVAVLKIGLELFYRAGPTIV
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
TALRDEGLLAPARPAEPAAPARVVSSVTGGDVTDGWGESHGSAAPELFLDLKLHDIPATV
EEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHH
AGGMRSLATLAPRFVTVHAAGGAAMVRAAVDAGPDVHVTAVTVLTSLDAATLAAVGLSGP
HHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCEEEEHHHHHHHCCHHHHHHCCCCCC
PSDAVRRLAVLAVEAGARALVCSPKEVSMVRAELGETVTLVTPGVRPEGSERADQARVAT
CHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHCCC
PERALADGSDLLVIGRPITSAADRAVAAATIATRVTPLR
CHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSSGAPRRWTPPAGRAPIAVALDAPDAATALGWAREVAPHVAVLKIGLELFYRAGPTIV
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
TALRDEGLLAPARPAEPAAPARVVSSVTGGDVTDGWGESHGSAAPELFLDLKLHDIPATV
EEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHH
AGGMRSLATLAPRFVTVHAAGGAAMVRAAVDAGPDVHVTAVTVLTSLDAATLAAVGLSGP
HHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCEEEEHHHHHHHCCHHHHHHCCCCCC
PSDAVRRLAVLAVEAGARALVCSPKEVSMVRAELGETVTLVTPGVRPEGSERADQARVAT
CHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHCCC
PERALADGSDLLVIGRPITSAADRAVAAATIATRVTPLR
CHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA