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The map label for this gene is aroC

Identifier: 158313535

GI number: 158313535

Start: 2031582

End: 2032766

Strand: Direct

Name: aroC

Synonym: Franean1_1699

Alternate gene names: 158313535

Gene position: 2031582-2032766 (Clockwise)

Preceding gene: 158313534

Following gene: 158313536

Centisome position: 22.62

GC content: 74.77

Gene sequence:

>1185_bases
ATGGTGCGTTGGTTGACAGCGGGGGAGTCACACGGCCCCGCACTGGTTGCGACGGTCGAGGGGTTGCCGGCGGGCATCCG
GGTGTCCAGCACGGACATCGGCGCCGAGCTGGCCCGGCGCCGTCTCGGCCACGGTCGCGGCGCCCGGATGAAGTTCGAGC
AGGATGAGATCGAGCTGCTCGGCGGCCTGCGGCACGGGGTCAGCCTGGGCGGCCCGGTGAGCGTCGTCGTGCGCAACACC
GAGTGGCCGAAGTGGGAGCGGGTGATGGCGCCCGACCCAATCGACCCGGCGGAGCTGGAGGGGCTGGGCCGCAACGCCCC
GCTCACCCGCCCGCGCCCGGGTCACGCCGACCTCGCCGGCATGCAGAAGTACGGCTTCGACGACGCGCGGCCGGTGCTGG
AGCGGGCGAGCGCCCGGGAGACGGCCGCCCGGGTCGCGCTGGGCACGGTCGCCAGGGCGCTGCTGCGCCAGGCGTACGGC
ATCGAGGTGGTCTCGCACGTCGTCGCGATCGGCGCGGTCGAGGTACCACCCGGCACGCCGCCGCCGACCTCGTTGGCCGT
CGTCGACGCCGACCCGGTGCGCTGTGCCGACCCGGCCAGCAGCGCGCTCATGGTCGCCGAGATCGACGCCGCCCACCGCG
ACGCGGACACCCTCGGCGGCATCGTCGAGGTGCTGGCCTACGGCTGCCCGCCGGGGCTGGGGAGCTACGTCCACGGCGAC
CGCCGGCTCGACGCGCGGCTCGCCGGCGAGCTGATGGGCATCCAGGCGATCAAGGGCGTCGAGTTCGGTGATGGTTTCCG
CACCGCGCGCCGGCGCGGATCGGTCGCCCACGACGAGATCGAGCCGCTCGAGGGGCCGGGTCGGCGGGTCCGGCGGGCCA
GCGATCGCGCCGGCGGAGTCGAGGGCGGGATGACGACAGGCGAGCCGCTGCGCGTCCGCGCGGCGATGAAGCCGATCTCA
TCCCTGTCGAAGCCGCTGGCCACGATCGACGTCGCCACCGGCGACCCGGCGGTCGCCATCGCCCAACGGTCGGACGTGTG
CGCGGTGCCGGCGGCCGGCGTGGTCGCCGAGGCGATGGTCGCCCTCGTGCTCGCCGGCGCAGCGCTGGAGAAGTTCGGCG
GCGACTCGGTGGAGGAGACCCGGCGCAACTACGAGGGCTACCTGAAGTCGCTGGCGGTGCGCTGA

Upstream 100 bases:

>100_bases
CTGATCGCGGTGCTCGGCGTGGGCTGGGAGCCGGCCGGCTGAGCGATCTCCGGCCCGCGACGGGGGCTCGTACCGGACCG
GCCGTGAAAGACTGGCAGGC

Downstream 100 bases:

>100_bases
CCATGCGCGCGGAGAGCGGGGCGCGGGCCGACGGGCCGGGGGCAGCTGTGTCCGGCCCGGTCGCCGTGCTGGTCGGCGCG
CCGGGGGCGGGTAAGAGCAC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MVRWLTAGESHGPALVATVEGLPAGIRVSSTDIGAELARRRLGHGRGARMKFEQDEIELLGGLRHGVSLGGPVSVVVRNT
EWPKWERVMAPDPIDPAELEGLGRNAPLTRPRPGHADLAGMQKYGFDDARPVLERASARETAARVALGTVARALLRQAYG
IEVVSHVVAIGAVEVPPGTPPPTSLAVVDADPVRCADPASSALMVAEIDAAHRDADTLGGIVEVLAYGCPPGLGSYVHGD
RRLDARLAGELMGIQAIKGVEFGDGFRTARRRGSVAHDEIEPLEGPGRRVRRASDRAGGVEGGMTTGEPLRVRAAMKPIS
SLSKPLATIDVATGDPAVAIAQRSDVCAVPAAGVVAEAMVALVLAGAALEKFGGDSVEETRRNYEGYLKSLAVR

Sequences:

>Translated_394_residues
MVRWLTAGESHGPALVATVEGLPAGIRVSSTDIGAELARRRLGHGRGARMKFEQDEIELLGGLRHGVSLGGPVSVVVRNT
EWPKWERVMAPDPIDPAELEGLGRNAPLTRPRPGHADLAGMQKYGFDDARPVLERASARETAARVALGTVARALLRQAYG
IEVVSHVVAIGAVEVPPGTPPPTSLAVVDADPVRCADPASSALMVAEIDAAHRDADTLGGIVEVLAYGCPPGLGSYVHGD
RRLDARLAGELMGIQAIKGVEFGDGFRTARRRGSVAHDEIEPLEGPGRRVRRASDRAGGVEGGMTTGEPLRVRAAMKPIS
SLSKPLATIDVATGDPAVAIAQRSDVCAVPAAGVVAEAMVALVLAGAALEKFGGDSVEETRRNYEGYLKSLAVR
>Mature_394_residues
MVRWLTAGESHGPALVATVEGLPAGIRVSSTDIGAELARRRLGHGRGARMKFEQDEIELLGGLRHGVSLGGPVSVVVRNT
EWPKWERVMAPDPIDPAELEGLGRNAPLTRPRPGHADLAGMQKYGFDDARPVLERASARETAARVALGTVARALLRQAYG
IEVVSHVVAIGAVEVPPGTPPPTSLAVVDADPVRCADPASSALMVAEIDAAHRDADTLGGIVEVLAYGCPPGLGSYVHGD
RRLDARLAGELMGIQAIKGVEFGDGFRTARRRGSVAHDEIEPLEGPGRRVRRASDRAGGVEGGMTTGEPLRVRAAMKPIS
SLSKPLATIDVATGDPAVAIAQRSDVCAVPAAGVVAEAMVALVLAGAALEKFGGDSVEETRRNYEGYLKSLAVR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=371, Percent_Identity=34.2318059299191, Blast_Score=164, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6321290, Length=378, Percent_Identity=31.7460317460317, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_FRASN (A8LE02)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001506043.1
- ProteinModelPortal:   A8LE02
- SMR:   A8LE02
- GeneID:   5670101
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_1699
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   FSP1855:FRANEAN1_1699-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 41250; Mature: 41250

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRWLTAGESHGPALVATVEGLPAGIRVSSTDIGAELARRRLGHGRGARMKFEQDEIELL
CCEEEECCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GGLRHGVSLGGPVSVVVRNTEWPKWERVMAPDPIDPAELEGLGRNAPLTRPRPGHADLAG
HHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHH
MQKYGFDDARPVLERASARETAARVALGTVARALLRQAYGIEVVSHVVAIGAVEVPPGTP
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCC
PPTSLAVVDADPVRCADPASSALMVAEIDAAHRDADTLGGIVEVLAYGCPPGLGSYVHGD
CCCEEEEEECCCCCCCCCCCCEEEEEECCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCC
RRLDARLAGELMGIQAIKGVEFGDGFRTARRRGSVAHDEIEPLEGPGRRVRRASDRAGGV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
EGGMTTGEPLRVRAAMKPISSLSKPLATIDVATGDPAVAIAQRSDVCAVPAAGVVAEAMV
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHH
ALVLAGAALEKFGGDSVEETRRNYEGYLKSLAVR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRWLTAGESHGPALVATVEGLPAGIRVSSTDIGAELARRRLGHGRGARMKFEQDEIELL
CCEEEECCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GGLRHGVSLGGPVSVVVRNTEWPKWERVMAPDPIDPAELEGLGRNAPLTRPRPGHADLAG
HHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHH
MQKYGFDDARPVLERASARETAARVALGTVARALLRQAYGIEVVSHVVAIGAVEVPPGTP
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCC
PPTSLAVVDADPVRCADPASSALMVAEIDAAHRDADTLGGIVEVLAYGCPPGLGSYVHGD
CCCEEEEEECCCCCCCCCCCCEEEEEECCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCC
RRLDARLAGELMGIQAIKGVEFGDGFRTARRRGSVAHDEIEPLEGPGRRVRRASDRAGGV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
EGGMTTGEPLRVRAAMKPISSLSKPLATIDVATGDPAVAIAQRSDVCAVPAAGVVAEAMV
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHH
ALVLAGAALEKFGGDSVEETRRNYEGYLKSLAVR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA