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The map label for this gene is aroE [H]

Identifier: 158313533

GI number: 158313533

Start: 2029908

End: 2030804

Strand: Direct

Name: aroE [H]

Synonym: Franean1_1697

Alternate gene names: 158313533

Gene position: 2029908-2030804 (Clockwise)

Preceding gene: 158313532

Following gene: 158313534

Centisome position: 22.6

GC content: 77.03

Gene sequence:

>897_bases
GTGGTGATCAGCTCTCGTGACCGTGCGGAGCCGGCCGGGCCGGGTCCGCACGCCGGGCGGGCGGCGGTGCTCGGCTCGCC
CATCGGTCACTCCCTCTCCCCGGTGCTGCACACGGCCGCCTACGAGCGGCTCGGCCTGGACTGGACCTACACGGCGATCG
AGTGCGACGAGGCCGGCCTGCCGGGCATGCTCGACCGCCTGCGTGACGAGCCCGGCTGGGCCGGGGTCTCGCTGACGATG
CCGCTCAAGACCGCCGCGGTCGACCTGCTTGACGACGTCGAGCCCACCGCGGCCCTGCTCGGCGCCGTGAACACCGTGGT
CGTCCGGGAGGACGGGCGGCTTGCCGGGTTCAACACCGACGTCGACGGCGTCGGGTACGCGCTGCGGCGGCTCACCGGCG
GCGTGGCCCCGGTCCAGCCGCTGGTGCTCGGGGCCGGCGGGACGGCGCGGGCGGTGGTCGCCGCGCTTGCCCGGGTCGGT
GCCACCCGGGTCGCGATCGTGGCGCGCCGCCCCGACGCGGTCGCCGAGCTCGTCGGCATCGGCGCCCGGCTCGGCGTCTC
GGTCACGGCGCTGCCCTGGGACATCCTCAGCGGCGGGATGCCGGCTGGGCCGGACCTGGTGGTCGCCACGACCCCCGCCG
GGGTGACCGACGAGCTCGCGCGTCGCCCGTGGCCGGTGACCTGCGCGTTGCTGGAGCTCCTTTACCACCCCTGGCCCACG
GCGCTGGCGGCCTGCGCCTACCGCGGCGGTGCGCGGGTGGTCGGCGGCCTCGAGGTGCTGGCCGGCCAGGCGGTCGGCCA
GGTGTGCCACTTCACCGGCCGCCCGGTGGACGAACGGGTCCTGCTCGCCGCCGGCCACGCGGCGCTGTCGGCCCGCGTCG
CGAGCCGGATCGGATGA

Upstream 100 bases:

>100_bases
TCTCCATGCCCCAGACGCACGAGACGGTCTTCGCCACCACCGACGCGGAGTTCCAGGACGCGCTGGACGAATACCATCGC
CAGGGAGGGGCCGAGTAGCC

Downstream 100 bases:

>100_bases
GCCCGGCGGTCGGATGAGCACGATGGTCAGGTGAACAGGGTGGTCAGGTGAACACGGTGGTGGTCGCCGCCACCGTGGCG
GCCGCGGTCTGCGCCGCGCT

Product: shikimate dehydrogenase substrate binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MVISSRDRAEPAGPGPHAGRAAVLGSPIGHSLSPVLHTAAYERLGLDWTYTAIECDEAGLPGMLDRLRDEPGWAGVSLTM
PLKTAAVDLLDDVEPTAALLGAVNTVVVREDGRLAGFNTDVDGVGYALRRLTGGVAPVQPLVLGAGGTARAVVAALARVG
ATRVAIVARRPDAVAELVGIGARLGVSVTALPWDILSGGMPAGPDLVVATTPAGVTDELARRPWPVTCALLELLYHPWPT
ALAACAYRGGARVVGGLEVLAGQAVGQVCHFTGRPVDERVLLAAGHAALSARVASRIG

Sequences:

>Translated_298_residues
MVISSRDRAEPAGPGPHAGRAAVLGSPIGHSLSPVLHTAAYERLGLDWTYTAIECDEAGLPGMLDRLRDEPGWAGVSLTM
PLKTAAVDLLDDVEPTAALLGAVNTVVVREDGRLAGFNTDVDGVGYALRRLTGGVAPVQPLVLGAGGTARAVVAALARVG
ATRVAIVARRPDAVAELVGIGARLGVSVTALPWDILSGGMPAGPDLVVATTPAGVTDELARRPWPVTCALLELLYHPWPT
ALAACAYRGGARVVGGLEVLAGQAVGQVCHFTGRPVDERVLLAAGHAALSARVASRIG
>Mature_298_residues
MVISSRDRAEPAGPGPHAGRAAVLGSPIGHSLSPVLHTAAYERLGLDWTYTAIECDEAGLPGMLDRLRDEPGWAGVSLTM
PLKTAAVDLLDDVEPTAALLGAVNTVVVREDGRLAGFNTDVDGVGYALRRLTGGVAPVQPLVLGAGGTARAVVAALARVG
ATRVAIVARRPDAVAELVGIGARLGVSVTALPWDILSGGMPAGPDLVVATTPAGVTDELARRPWPVTCALLELLYHPWPT
ALAACAYRGGARVVGGLEVLAGQAVGQVCHFTGRPVDERVLLAAGHAALSARVASRIG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=265, Percent_Identity=29.4339622641509, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789675, Length=247, Percent_Identity=32.3886639676113, Blast_Score=96, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320332, Length=161, Percent_Identity=36.0248447204969, Blast_Score=92, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30458; Mature: 30458

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVISSRDRAEPAGPGPHAGRAAVLGSPIGHSLSPVLHTAAYERLGLDWTYTAIECDEAGL
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCC
PGMLDRLRDEPGWAGVSLTMPLKTAAVDLLDDVEPTAALLGAVNTVVVREDGRLAGFNTD
CHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCEEECCCCC
VDGVGYALRRLTGGVAPVQPLVLGAGGTARAVVAALARVGATRVAIVARRPDAVAELVGI
CHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHC
GARLGVSVTALPWDILSGGMPAGPDLVVATTPAGVTDELARRPWPVTCALLELLYHPWPT
CHHHCCEEEECCHHHHCCCCCCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHHHHCCCHH
ALAACAYRGGARVVGGLEVLAGQAVGQVCHFTGRPVDERVLLAAGHAALSARVASRIG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHCC
>Mature Secondary Structure
MVISSRDRAEPAGPGPHAGRAAVLGSPIGHSLSPVLHTAAYERLGLDWTYTAIECDEAGL
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCC
PGMLDRLRDEPGWAGVSLTMPLKTAAVDLLDDVEPTAALLGAVNTVVVREDGRLAGFNTD
CHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCEEECCCCC
VDGVGYALRRLTGGVAPVQPLVLGAGGTARAVVAALARVGATRVAIVARRPDAVAELVGI
CHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHC
GARLGVSVTALPWDILSGGMPAGPDLVVATTPAGVTDELARRPWPVTCALLELLYHPWPT
CHHHCCEEEECCHHHHCCCCCCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHHHHCCCHH
ALAACAYRGGARVVGGLEVLAGQAVGQVCHFTGRPVDERVLLAAGHAALSARVASRIG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA