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The map label for this gene is rfbB [C]

Identifier: 158313510

GI number: 158313510

Start: 2002656

End: 2003615

Strand: Direct

Name: rfbB [C]

Synonym: Franean1_1674

Alternate gene names: 158313510

Gene position: 2002656-2003615 (Clockwise)

Preceding gene: 158313509

Following gene: 158313514

Centisome position: 22.3

GC content: 69.48

Gene sequence:

>960_bases
ATGCGTGTCGTCGTCGCGGGAGGCGCGGGCTTCCTGGGGAGCCATCTCTGTGATCGGCTGCTCCTGGATGGTGAGGAGGT
TGTGTGCATCGACAACTTTCTCACCGGGCGGAAGAGCAATGTCGAGCATCTACTCGACCGGCCAGGATTCGAGCTCCTCG
AGCAGGACGTCGCTGAGCGGGTCGAGGTGGCCGGGACGGTCGACGCCGTCCTGGAGTTCGCGTCACCGGCGTCGCCTCTC
GACTACGCCCGGTATCCGATTGAGACCTTGAAGGCAGGCGCGCACGGCACGCTCAACACGCTCGACCTCGCCCGGGCGAA
GGGCGCCCGCTTCCTGCTGGCGTCGACCTCCGAGGTCTACGGGGACCCGCTGGTGCACCCGCAGGAGGAGTCGTACTGGG
GGCACGTCAACCCGATCGGCCCGCGCAGCATGTACGACGAGGCCAAGCGTTTCGCCGAGGCGCTGACCACCGCCTACCGC
AACCGGCATGGGCTCGACACGGCGATCATCCGGATCTTTAACACCTACGGGCCGCGGATGCGCACCGACGACGGCCGGGC
GATTCCCGCGTTCGTCTCCCAGGCCCTGCGCGGTGAGCCGGTGACCGTCGCCGGCGACGGGATGCAGACCCGCTCGGTCT
GCTACGTGGACGACCTCGTCGAGGGCATCGTGCGGATGCTGCGCAGCGGCCTGCCCGGCCCGGTGAACCTCGGCAACCCG
CACGAGATGACGATCATCGACACCGCACGCCTGGTGGTCGAGCTGATCGGCTCCGACGCGCCGATCACGTTCGTGCCGCG
GCCCGGCGACGACCCGATGGTCCGCCGGCCGGACATCACCCTCGCCCGTCAGCAACTCGGCTGGGAGCCGGTCGTCGACG
TGCGCGACGGGCTGGTCCGGACCATCGAGTGGTTCGCGAGCGAGCTCGCCACCGAGTCGGCGGGCCGGACCGGCGCGTAG

Upstream 100 bases:

>100_bases
CCGGCCCGAGAGGCAGCGGGGATAGGCCACCGCCGACATCGGTGGTGGGTGTTCTTTCGTCGGTATTCGTTGAGCTGCCA
GTGCTGGGGGTTTTTCGGCT

Downstream 100 bases:

>100_bases
CCCGGGTCTGGCCCGGGCCAGACCCAGGTCAGACCTGGGGGAGGACCTCGGCGGCGAGCAACGCCACGTGGTCGAGGTCG
TCCAGGTCGAGGACCTGCAG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRVVVAGGAGFLGSHLCDRLLLDGEEVVCIDNFLTGRKSNVEHLLDRPGFELLEQDVAERVEVAGTVDAVLEFASPASPL
DYARYPIETLKAGAHGTLNTLDLARAKGARFLLASTSEVYGDPLVHPQEESYWGHVNPIGPRSMYDEAKRFAEALTTAYR
NRHGLDTAIIRIFNTYGPRMRTDDGRAIPAFVSQALRGEPVTVAGDGMQTRSVCYVDDLVEGIVRMLRSGLPGPVNLGNP
HEMTIIDTARLVVELIGSDAPITFVPRPGDDPMVRRPDITLARQQLGWEPVVDVRDGLVRTIEWFASELATESAGRTGA

Sequences:

>Translated_319_residues
MRVVVAGGAGFLGSHLCDRLLLDGEEVVCIDNFLTGRKSNVEHLLDRPGFELLEQDVAERVEVAGTVDAVLEFASPASPL
DYARYPIETLKAGAHGTLNTLDLARAKGARFLLASTSEVYGDPLVHPQEESYWGHVNPIGPRSMYDEAKRFAEALTTAYR
NRHGLDTAIIRIFNTYGPRMRTDDGRAIPAFVSQALRGEPVTVAGDGMQTRSVCYVDDLVEGIVRMLRSGLPGPVNLGNP
HEMTIIDTARLVVELIGSDAPITFVPRPGDDPMVRRPDITLARQQLGWEPVVDVRDGLVRTIEWFASELATESAGRTGA
>Mature_319_residues
MRVVVAGGAGFLGSHLCDRLLLDGEEVVCIDNFLTGRKSNVEHLLDRPGFELLEQDVAERVEVAGTVDAVLEFASPASPL
DYARYPIETLKAGAHGTLNTLDLARAKGARFLLASTSEVYGDPLVHPQEESYWGHVNPIGPRSMYDEAKRFAEALTTAYR
NRHGLDTAIIRIFNTYGPRMRTDDGRAIPAFVSQALRGEPVTVAGDGMQTRSVCYVDDLVEGIVRMLRSGLPGPVNLGNP
HEMTIIDTARLVVELIGSDAPITFVPRPGDDPMVRRPDITLARQQLGWEPVVDVRDGLVRTIEWFASELATESAGRTGA

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=53.015873015873, Blast_Score=355, Evalue=3e-98,
Organism=Homo sapiens, GI7657641, Length=322, Percent_Identity=28.8819875776398, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=25.9475218658892, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=25.9475218658892, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=25.9475218658892, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI48994969, Length=343, Percent_Identity=27.6967930029155, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788353, Length=354, Percent_Identity=26.5536723163842, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788589, Length=337, Percent_Identity=27.0029673590504, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786974, Length=318, Percent_Identity=27.0440251572327, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788366, Length=347, Percent_Identity=27.6657060518732, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=315, Percent_Identity=49.2063492063492, Blast_Score=327, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI17568069, Length=327, Percent_Identity=29.0519877675841, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115532424, Length=324, Percent_Identity=28.3950617283951, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982035, Length=327, Percent_Identity=25.9938837920489, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=25.1461988304094, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=51.1326860841424, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI19923002, Length=326, Percent_Identity=25.4601226993865, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34804; Mature: 34804

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVVAGGAGFLGSHLCDRLLLDGEEVVCIDNFLTGRKSNVEHLLDRPGFELLEQDVAER
CEEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHCCCCCCHHHHHCCCCHHHHHHHHHHH
VEVAGTVDAVLEFASPASPLDYARYPIETLKAGAHGTLNTLDLARAKGARFLLASTSEVY
HHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCEEEEECCHHHC
GDPLVHPQEESYWGHVNPIGPRSMYDEAKRFAEALTTAYRNRHGLDTAIIRIFNTYGPRM
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCE
RTDDGRAIPAFVSQALRGEPVTVAGDGMQTRSVCYVDDLVEGIVRMLRSGLPGPVNLGNP
ECCCCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
HEMTIIDTARLVVELIGSDAPITFVPRPGDDPMVRRPDITLARQQLGWEPVVDVRDGLVR
CEEEEHHHHHHHHHHHCCCCCEEEECCCCCCCCEECCCHHHHHHHCCCCCHHHHHHHHHH
TIEWFASELATESAGRTGA
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRVVVAGGAGFLGSHLCDRLLLDGEEVVCIDNFLTGRKSNVEHLLDRPGFELLEQDVAER
CEEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHCCCCCCHHHHHCCCCHHHHHHHHHHH
VEVAGTVDAVLEFASPASPLDYARYPIETLKAGAHGTLNTLDLARAKGARFLLASTSEVY
HHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCEEEEECCHHHC
GDPLVHPQEESYWGHVNPIGPRSMYDEAKRFAEALTTAYRNRHGLDTAIIRIFNTYGPRM
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCE
RTDDGRAIPAFVSQALRGEPVTVAGDGMQTRSVCYVDDLVEGIVRMLRSGLPGPVNLGNP
ECCCCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
HEMTIIDTARLVVELIGSDAPITFVPRPGDDPMVRRPDITLARQQLGWEPVVDVRDGLVR
CEEEEHHHHHHHHHHHCCCCCEEEECCCCCCCCEECCCHHHHHHHCCCCCHHHHHHHHHH
TIEWFASELATESAGRTGA
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]