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The map label for this gene is yhcA [H]

Identifier: 158313487

GI number: 158313487

Start: 1970962

End: 1972887

Strand: Direct

Name: yhcA [H]

Synonym: Franean1_1651

Alternate gene names: 158313487

Gene position: 1970962-1972887 (Clockwise)

Preceding gene: 158313486

Following gene: 158313490

Centisome position: 21.94

GC content: 71.5

Gene sequence:

>1926_bases
ATGACGGCCGTCACCAAGCACGGCGATCGCCGCTGGGCCGTCCTGGCCAACACGACCGCCGCGGTCTTCATGTCGGCGCT
CGACGGCTCCATCGTCCTGATCGCCCTGCCGCCGATCTTCCTCGGCATCGACCTGGATCCGCTGGCGCCCGGTAACGTGA
GCTATCTGCTATGGATGATCATGGGATACCGCCTGGTGCAGGCGGTGCTCGTCGTGCCGCTGGGGCGGCTGGGTGACATG
TTCGGCCGGGTGCGGATCTACAACGCCGGCTTTGTGGTCTTCACCGTCGCCTCCATCCTGCTGTCCTTCGATCCCTTCCA
CGGGCGCAGCGCCGCGATGTGGCTGATCGGCTGGCGCGTGCTGCAGGCGGTCGGCGGCTCCATGCTGGCCGCCAACTCGG
CCGCGATCCTCACCGACGTGTTCCCGCCCGACCAGCGCGGTCTGGCGCTCGGCATCAACCAGGTCGCCGCGCTCGCCGGG
CAGTTCATCGGCCTGGTCGCCGGCGGGGTGCTGGCCGTCCTGGACTGGCGTGCGGTGTTCTGGGTGAACGTGCCCGTCGG
TGTGTTCGGCACCATCTGGGCCTACCGGACGCTGCGCGAGCCCGAGCGCCGGGACCGCCCGGAACGGGGCCGCTTCGACT
GGTGGGGCAACATCACCTTCTCGGTGGGCCTGGGGGCGGTGCTGATCGCCGTCACCGAGGGCCTGCAGCCCTACAAGAAC
CACGCGATGGCCTGGATCAGCCCCAAGGTCCTGGTGCTGCTCATCGGGGGCGTGGCGCTGCTGGCCGCCTTCGTCGTGAT
CGAGAAGCGGTTCGAGTCGCCGATGTTCGAGCTCTCGCTGTTCCGTATCCGGGCCTTCAGCGCCGGGAACGCGGCCGGCC
TGGCGGTGTCGGTCGCGCGCGGCGGTCTGCAGTTCATGCTGATCATCTGGCTGCAGGGGATCTGGCTGCCCCTGCACGGC
TACGACTTCGACGACACCCCGTTCTGGGCCGGAATCTACCTGTTGCCACTGACCGCCGGTGTCCTCGTGGCAGGCCCGCT
GTCGGGGTTCCTGTCCGACCGCTCCGGCGCCCGCGGCCTGGCCACCACCGGGATGCTGGTGTTCGCGGGCAGCTTCGTCG
GCCTCATGCTGCTGCCCGTCAACTTCTCCTACTGGGCGTTCGGCCTGCTGATCACCGTGAACGGCATCGGCGCCGGAATG
TTCGCCGCGCCGAACTCGTCCTCGATCATGAGCAGCGTCCCGGCGCACCTGCGCGGGGTCGGATCCGGGATGCGCTCGAC
CTTCCAGAACGCCGGCGGCGCGCTGTCCATCGGGCTCTTCTTCTCACTCATGGTCGCCGGGCTGGCGGGCAGCCTGCCGG
GCGCCTTCTCCGCCGGTCTGCGGGCGGAGGGCGTGCCCGCCGACGTCGCCCAGCAGGTCGGTTCCCTGCCCCCGGTCGCG
TCGCTGTTCGCCGCGGTGCTCGGCCTGAACCCGGTCGAGCACCTGCTGAGCTCGACCAGCACGCTGGACGACCTGACGCC
GGACCACCGGGCGACCGTCACCGGTCGCGAGTTCTTCCCCCACCTCATCTCGACGCCGTTCCACGACGGCCTCGTCGTCG
TGTTCGTGGCCTCGGCCCTGCTCGGCCTCATCGCCGCGGCGGCGTCGGCGATGCGCGGTGCCCACCACGTCGAGCGGGAC
CCGCTCGAGCCGGTCCCGCTCGCGGTGGGCCTCCTCGAGTCGGTGCCGGCGGAGCCCGTCCTCCTCGAGGCGTCGGGCCG
TGATCGGGTCGGGACCGGTGCTGCCGGGGCCGACGTATCTGGGGCTGAGGTGCCCGGGGCGGACTCGCCCGGGGTCGACG
CGGCCGGTCCCGGGCCCGGAGCGTCGGGTCCGGCTGGGCCGGGTCCGGGCGCGACCGGACCGCTCAGAGGCGGCCCCCTG
GGGTGA

Upstream 100 bases:

>100_bases
AGCAGCTCGCGCGGGCGCTGTCCAGCGGCTTCGACGACGACGAGCTGGCCTGCCTGAAGGCCGCCGCGCCGCTGCTCGAG
CGCCTGGCGCAGCGCATCTG

Downstream 100 bases:

>100_bases
CCAGTCCCGTCTCGTAGGCGACGACGACCGCCTGCACCCGGTCCCGCAGCCGCAGTTTGCCGAGGATCCGGGCCACATGA
GTCTTCACCGTGGCCTCACT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MTAVTKHGDRRWAVLANTTAAVFMSALDGSIVLIALPPIFLGIDLDPLAPGNVSYLLWMIMGYRLVQAVLVVPLGRLGDM
FGRVRIYNAGFVVFTVASILLSFDPFHGRSAAMWLIGWRVLQAVGGSMLAANSAAILTDVFPPDQRGLALGINQVAALAG
QFIGLVAGGVLAVLDWRAVFWVNVPVGVFGTIWAYRTLREPERRDRPERGRFDWWGNITFSVGLGAVLIAVTEGLQPYKN
HAMAWISPKVLVLLIGGVALLAAFVVIEKRFESPMFELSLFRIRAFSAGNAAGLAVSVARGGLQFMLIIWLQGIWLPLHG
YDFDDTPFWAGIYLLPLTAGVLVAGPLSGFLSDRSGARGLATTGMLVFAGSFVGLMLLPVNFSYWAFGLLITVNGIGAGM
FAAPNSSSIMSSVPAHLRGVGSGMRSTFQNAGGALSIGLFFSLMVAGLAGSLPGAFSAGLRAEGVPADVAQQVGSLPPVA
SLFAAVLGLNPVEHLLSSTSTLDDLTPDHRATVTGREFFPHLISTPFHDGLVVVFVASALLGLIAAAASAMRGAHHVERD
PLEPVPLAVGLLESVPAEPVLLEASGRDRVGTGAAGADVSGAEVPGADSPGVDAAGPGPGASGPAGPGPGATGPLRGGPL
G

Sequences:

>Translated_641_residues
MTAVTKHGDRRWAVLANTTAAVFMSALDGSIVLIALPPIFLGIDLDPLAPGNVSYLLWMIMGYRLVQAVLVVPLGRLGDM
FGRVRIYNAGFVVFTVASILLSFDPFHGRSAAMWLIGWRVLQAVGGSMLAANSAAILTDVFPPDQRGLALGINQVAALAG
QFIGLVAGGVLAVLDWRAVFWVNVPVGVFGTIWAYRTLREPERRDRPERGRFDWWGNITFSVGLGAVLIAVTEGLQPYKN
HAMAWISPKVLVLLIGGVALLAAFVVIEKRFESPMFELSLFRIRAFSAGNAAGLAVSVARGGLQFMLIIWLQGIWLPLHG
YDFDDTPFWAGIYLLPLTAGVLVAGPLSGFLSDRSGARGLATTGMLVFAGSFVGLMLLPVNFSYWAFGLLITVNGIGAGM
FAAPNSSSIMSSVPAHLRGVGSGMRSTFQNAGGALSIGLFFSLMVAGLAGSLPGAFSAGLRAEGVPADVAQQVGSLPPVA
SLFAAVLGLNPVEHLLSSTSTLDDLTPDHRATVTGREFFPHLISTPFHDGLVVVFVASALLGLIAAAASAMRGAHHVERD
PLEPVPLAVGLLESVPAEPVLLEASGRDRVGTGAAGADVSGAEVPGADSPGVDAAGPGPGASGPAGPGPGATGPLRGGPL
G
>Mature_640_residues
TAVTKHGDRRWAVLANTTAAVFMSALDGSIVLIALPPIFLGIDLDPLAPGNVSYLLWMIMGYRLVQAVLVVPLGRLGDMF
GRVRIYNAGFVVFTVASILLSFDPFHGRSAAMWLIGWRVLQAVGGSMLAANSAAILTDVFPPDQRGLALGINQVAALAGQ
FIGLVAGGVLAVLDWRAVFWVNVPVGVFGTIWAYRTLREPERRDRPERGRFDWWGNITFSVGLGAVLIAVTEGLQPYKNH
AMAWISPKVLVLLIGGVALLAAFVVIEKRFESPMFELSLFRIRAFSAGNAAGLAVSVARGGLQFMLIIWLQGIWLPLHGY
DFDDTPFWAGIYLLPLTAGVLVAGPLSGFLSDRSGARGLATTGMLVFAGSFVGLMLLPVNFSYWAFGLLITVNGIGAGMF
AAPNSSSIMSSVPAHLRGVGSGMRSTFQNAGGALSIGLFFSLMVAGLAGSLPGAFSAGLRAEGVPADVAQQVGSLPPVAS
LFAAVLGLNPVEHLLSSTSTLDDLTPDHRATVTGREFFPHLISTPFHDGLVVVFVASALLGLIAAAASAMRGAHHVERDP
LEPVPLAVGLLESVPAEPVLLEASGRDRVGTGAAGADVSGAEVPGADSPGVDAAGPGPGASGPAGPGPGATGPLRGGPLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=432, Percent_Identity=25.462962962963, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1790195, Length=340, Percent_Identity=28.5294117647059, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788710, Length=456, Percent_Identity=23.9035087719298, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789042, Length=354, Percent_Identity=26.5536723163842, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788392, Length=445, Percent_Identity=25.6179775280899, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324954, Length=424, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 66543; Mature: 66412

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVTKHGDRRWAVLANTTAAVFMSALDGSIVLIALPPIFLGIDLDPLAPGNVSYLLWMI
CCCCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHH
MGYRLVQAVLVVPLGRLGDMFGRVRIYNAGFVVFTVASILLSFDPFHGRSAAMWLIGWRV
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LQAVGGSMLAANSAAILTDVFPPDQRGLALGINQVAALAGQFIGLVAGGVLAVLDWRAVF
HHHHCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
WVNVPVGVFGTIWAYRTLREPERRDRPERGRFDWWGNITFSVGLGAVLIAVTEGLQPYKN
EEECCHHHHHHHHHHHHHCCHHHHCCCCCCCCEEECCEEEEHHHHHHHHHHHHCCCHHHH
HAMAWISPKVLVLLIGGVALLAAFVVIEKRFESPMFELSLFRIRAFSAGNAAGLAVSVAR
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEHHHEEECCCCCCCEEEEEHH
GGLQFMLIIWLQGIWLPLHGYDFDDTPFWAGIYLLPLTAGVLVAGPLSGFLSDRSGARGL
CCHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCH
ATTGMLVFAGSFVGLMLLPVNFSYWAFGLLITVNGIGAGMFAAPNSSSIMSSVPAHLRGV
HHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCEEECCCCCHHHHHHHHHHHHH
GSGMRSTFQNAGGALSIGLFFSLMVAGLAGSLPGAFSAGLRAEGVPADVAQQVGSLPPVA
HHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHCCCCCHH
SLFAAVLGLNPVEHLLSSTSTLDDLTPDHRATVTGREFFPHLISTPFHDGLVVVFVASAL
HHHHHHHCCCHHHHHHHCCCHHHHCCCCCCEEECHHHHHHHHHCCCCCCCHHHHHHHHHH
LGLIAAAASAMRGAHHVERDPLEPVPLAVGLLESVPAEPVLLEASGRDRVGTGAAGADVS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC
GAEVPGADSPGVDAAGPGPGASGPAGPGPGATGPLRGGPLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAVTKHGDRRWAVLANTTAAVFMSALDGSIVLIALPPIFLGIDLDPLAPGNVSYLLWMI
CCCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHH
MGYRLVQAVLVVPLGRLGDMFGRVRIYNAGFVVFTVASILLSFDPFHGRSAAMWLIGWRV
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LQAVGGSMLAANSAAILTDVFPPDQRGLALGINQVAALAGQFIGLVAGGVLAVLDWRAVF
HHHHCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
WVNVPVGVFGTIWAYRTLREPERRDRPERGRFDWWGNITFSVGLGAVLIAVTEGLQPYKN
EEECCHHHHHHHHHHHHHCCHHHHCCCCCCCCEEECCEEEEHHHHHHHHHHHHCCCHHHH
HAMAWISPKVLVLLIGGVALLAAFVVIEKRFESPMFELSLFRIRAFSAGNAAGLAVSVAR
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEHHHEEECCCCCCCEEEEEHH
GGLQFMLIIWLQGIWLPLHGYDFDDTPFWAGIYLLPLTAGVLVAGPLSGFLSDRSGARGL
CCHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCH
ATTGMLVFAGSFVGLMLLPVNFSYWAFGLLITVNGIGAGMFAAPNSSSIMSSVPAHLRGV
HHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCEEECCCCCHHHHHHHHHHHHH
GSGMRSTFQNAGGALSIGLFFSLMVAGLAGSLPGAFSAGLRAEGVPADVAQQVGSLPPVA
HHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHCCCCCHH
SLFAAVLGLNPVEHLLSSTSTLDDLTPDHRATVTGREFFPHLISTPFHDGLVVVFVASAL
HHHHHHHCCCHHHHHHHCCCHHHHCCCCCCEEECHHHHHHHHHCCCCCCCHHHHHHHHHH
LGLIAAAASAMRGAHHVERDPLEPVPLAVGLLESVPAEPVLLEASGRDRVGTGAAGADVS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC
GAEVPGADSPGVDAAGPGPGASGPAGPGPGATGPLRGGPLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8969498 [H]