Click here to switch to the map view.

The map label for this gene is gltC [H]

Identifier: 158313455

GI number: 158313455

Start: 1935780

End: 1936715

Strand: Direct

Name: gltC [H]

Synonym: Franean1_1618

Alternate gene names: 158313455

Gene position: 1935780-1936715 (Clockwise)

Preceding gene: 158313453

Following gene: 158313459

Centisome position: 21.55

GC content: 74.36

Gene sequence:

>936_bases
ATGGAGCTGCGCCAGTTGGAGTACTTCGTCGCGGTCGCCGAGGAGCGGAACTTCACCCGGGCGGCCGAGCGCAGCCACGT
CAGCCAGTCCGGAGTCAGCGCACAGATCCGCCAGCTCGAACGGGATCTCGGCGCCGAGCTGTTCGACCGGTCCGGTCGCG
CCGCGACGCTCACCCCCGCGGGGGAGGCCGCGCTGGAATGTGCGCGTGCCGCGCTCGCCGCCACCGCGGCCCTGCGCCAG
GCGGTCGGCGAGGTCACCGGCCTGATCCGCGGCCAGCTCACCGTCGGGATGGTCACCGGCTGCACCGTCACGCCGCTGTT
CGACGCCCTCGCCGGTTTCCGCGGTGCCCACCCAGGGGTGGACGTCTCCCTGCTGGAAGGCAACTCCGACCAGCTCGTCT
CGGAGGTCCGTGCCGGGACGGTCGACCTGGCCCTGGTGGGCAGCGCCGCCCCGGCCCCCGAGGGACTGGGGGCGCTGACG
ATCGTCGAGGAGCGGCTGGTGGCGGCCGTCCAGCCCGGTCACCTCCTGGCGGAGCGGCCCCGGATCACCCTGCGTGACCT
GTGTCGGCATCCGATCGTGTGCATGCCCCCCGGTACCGGCCTGCGCACCGTGTTCGACCGGGCCTGCCAGACCTGCGACC
TTCACCCCAGAATCACGTTGCAGGCCAGCGCGCCGGACGCCATCGCCGACCTCGCCGGCCGGGGCCTGGGCGTGGCCGTC
CTCAGCACGTCCATGGTGGCGGCGTACGGCGACCGGCTCGTCGCGCTACCCGTGGACGGCCTCGACCTACCGGCGCTGCT
CACCCTCGTCTGGCGCGCCCCGGCCAGCCCCGCCGTCCGCGAACTGCTCGCCCACGCCCGCCGGGCCTTCGCCGTCCCCG
ATCCGGACGGTCCCGCGAACGGTGTTCCAGCCCCGCCACGGCAGACCCCCACCTGA

Upstream 100 bases:

>100_bases
CATGGCTTCTCCCTGGTCGGCTGTGTCCTGCCGTCCAGCCTGGGACCGGGGGAGCCAGAAGTCCAACAGATGGATCTGCT
CGCAGCTAGCATCTTTGCTT

Downstream 100 bases:

>100_bases
CTGAGCCCGACACGACGGAGCCGGGTCACCCGGCCCGGCGGGCGGTGACGATGTACGCGGTCTCACTGAACAGGAAGTCG
CCGTCGTCCTGAGCCGCCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MELRQLEYFVAVAEERNFTRAAERSHVSQSGVSAQIRQLERDLGAELFDRSGRAATLTPAGEAALECARAALAATAALRQ
AVGEVTGLIRGQLTVGMVTGCTVTPLFDALAGFRGAHPGVDVSLLEGNSDQLVSEVRAGTVDLALVGSAAPAPEGLGALT
IVEERLVAAVQPGHLLAERPRITLRDLCRHPIVCMPPGTGLRTVFDRACQTCDLHPRITLQASAPDAIADLAGRGLGVAV
LSTSMVAAYGDRLVALPVDGLDLPALLTLVWRAPASPAVRELLAHARRAFAVPDPDGPANGVPAPPRQTPT

Sequences:

>Translated_311_residues
MELRQLEYFVAVAEERNFTRAAERSHVSQSGVSAQIRQLERDLGAELFDRSGRAATLTPAGEAALECARAALAATAALRQ
AVGEVTGLIRGQLTVGMVTGCTVTPLFDALAGFRGAHPGVDVSLLEGNSDQLVSEVRAGTVDLALVGSAAPAPEGLGALT
IVEERLVAAVQPGHLLAERPRITLRDLCRHPIVCMPPGTGLRTVFDRACQTCDLHPRITLQASAPDAIADLAGRGLGVAV
LSTSMVAAYGDRLVALPVDGLDLPALLTLVWRAPASPAVRELLAHARRAFAVPDPDGPANGVPAPPRQTPT
>Mature_311_residues
MELRQLEYFVAVAEERNFTRAAERSHVSQSGVSAQIRQLERDLGAELFDRSGRAATLTPAGEAALECARAALAATAALRQ
AVGEVTGLIRGQLTVGMVTGCTVTPLFDALAGFRGAHPGVDVSLLEGNSDQLVSEVRAGTVDLALVGSAAPAPEGLGALT
IVEERLVAAVQPGHLLAERPRITLRDLCRHPIVCMPPGTGLRTVFDRACQTCDLHPRITLQASAPDAIADLAGRGLGVAV
LSTSMVAAYGDRLVALPVDGLDLPALLTLVWRAPASPAVRELLAHARRAFAVPDPDGPANGVPAPPRQTPT

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=295, Percent_Identity=34.5762711864407, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI157672245, Length=255, Percent_Identity=32.156862745098, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=32.0158102766798, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788887, Length=299, Percent_Identity=33.1103678929766, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790399, Length=303, Percent_Identity=29.3729372937294, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367136, Length=284, Percent_Identity=26.4084507042254, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790208, Length=243, Percent_Identity=30.0411522633745, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787601, Length=301, Percent_Identity=24.9169435215947, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788481, Length=300, Percent_Identity=28.3333333333333, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789173, Length=194, Percent_Identity=32.4742268041237, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693105, Length=206, Percent_Identity=23.3009708737864, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=26.6393442622951, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788748, Length=240, Percent_Identity=25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994962, Length=169, Percent_Identity=29.585798816568, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081904, Length=212, Percent_Identity=27.3584905660377, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=167, Percent_Identity=28.1437125748503, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787806, Length=148, Percent_Identity=32.4324324324324, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788706, Length=193, Percent_Identity=28.4974093264249, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI145693193, Length=240, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787589, Length=123, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790262, Length=249, Percent_Identity=24.4979919678715, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786713, Length=278, Percent_Identity=26.978417266187, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=244, Percent_Identity=26.2295081967213, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32436; Mature: 32436

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRQLEYFVAVAEERNFTRAAERSHVSQSGVSAQIRQLERDLGAELFDRSGRAATLTPA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHCCCCEEEECCC
GEAALECARAALAATAALRQAVGEVTGLIRGQLTVGMVTGCTVTPLFDALAGFRGAHPGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCC
DVSLLEGNSDQLVSEVRAGTVDLALVGSAAPAPEGLGALTIVEERLVAAVQPGHLLAERP
EEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCC
RITLRDLCRHPIVCMPPGTGLRTVFDRACQTCDLHPRITLQASAPDAIADLAGRGLGVAV
CCHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHCCCCCHHH
LSTSMVAAYGDRLVALPVDGLDLPALLTLVWRAPASPAVRELLAHARRAFAVPDPDGPAN
HHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
GVPAPPRQTPT
CCCCCCCCCCC
>Mature Secondary Structure
MELRQLEYFVAVAEERNFTRAAERSHVSQSGVSAQIRQLERDLGAELFDRSGRAATLTPA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHCCCCEEEECCC
GEAALECARAALAATAALRQAVGEVTGLIRGQLTVGMVTGCTVTPLFDALAGFRGAHPGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCC
DVSLLEGNSDQLVSEVRAGTVDLALVGSAAPAPEGLGALTIVEERLVAAVQPGHLLAERP
EEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCC
RITLRDLCRHPIVCMPPGTGLRTVFDRACQTCDLHPRITLQASAPDAIADLAGRGLGVAV
CCHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHCCCCCHHH
LSTSMVAAYGDRLVALPVDGLDLPALLTLVWRAPASPAVRELLAHARRAFAVPDPDGPAN
HHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
GVPAPPRQTPT
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]