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The map label for this gene is yajO [H]

Identifier: 158313393

GI number: 158313393

Start: 1863560

End: 1864609

Strand: Direct

Name: yajO [H]

Synonym: Franean1_1556

Alternate gene names: 158313393

Gene position: 1863560-1864609 (Clockwise)

Preceding gene: 158313392

Following gene: 158313395

Centisome position: 20.75

GC content: 70.1

Gene sequence:

>1050_bases
ATGCGGTACCGCAAGTTCGGGCGGACGGGCATCGAGGTCAGCCGGCAGTGCCTGGGATCCATGATGTTCGGTGTGATCGG
CAACCCCGACCACGCCGCGTGCGAGCGCATCATCGCCCGGGCGCTGGACGCCGGGATCAACTTCATCGACACCGCCGACA
TCTACTCGCGGGGTGAGAGCGAGCAGATCGTCGGGAAGGCCATCAAGGGCCGCCGCGACGACATCGTCCTGGCCACCAAG
TGCTTCAACCCGATGGGCGGGGACCGCAACCGCCGCGGCGCCTCCCGCCGGTGGATCACGCGCGCCGTCGAGGACAGCCT
CCGCCGCCTCGACACCGACTACATCGACCTCTTCCAGATCCACCGGCATGACTGGAACACCGACCTGGAAGAGACCCTCG
GCGCGCTGAACGACCTCGTGCACCAGGGCAAGATCCGTTACCTGGGCTCGTCGACGTTTCCCGCGGACTGGATCGTCGAG
GCGCAGTGGGCCGCCCGCCGCCGCAACACCGAGCGTTTCGTCTGCGAGCAGCCCCAGTACTCGATCTTCGCCCGCTCGGT
CGAGCAGGCCGTCCTGCCCGCCTGCCGGCGGCACGACATCGCGGTGATTCCCTGGAGCCCGCTCTCCGGCGGCTGGCTGA
CCGGGAAGTACCGGCGCGGGCAGGCGGTGCCGGCCGACGCCCGGTACGCGGCCGGCAATGTCATGGCACAGGGGCGGGCC
GTCGGGGAGAGCCCCGAGTCGCAGGCCCGGTTCGACGCGGTCGAGCAGCTGTCCGCGGTGGCGGCGGAGGCCGGCCTCTC
CCTCACCCATCTTGCGCTCGGGTTCGTGGAGAGCCATCCGGCGATCACTTCGACGATCATCGGCCCGCGCACGATGGAGC
AGCTCGAGGACGTCCTCAGCGGGGCCGACGTCGTGCTCGACGCGGCGACGCTCGACGCGATCGACAAGATCGTGGAGCCC
GGGACCGATTTCGTCGGCGTCCGGCACATGACCGGTGACCCGTCCCTGCTGCCCGAGACGCGCCGGCGGCTGGCAACGCA
GTTCGGCTGA

Upstream 100 bases:

>100_bases
GCGGGGGTGCGTCGCGACGATCGCTGGTGAAATGCTGGGCCGGGCAGGCAGCGGGACGGCCGGCGGGGCCGGGCAACTGT
GGGTGACGGAAGGCGGGAAC

Downstream 100 bases:

>100_bases
CCCGGCCCCGGCCGATGCCCTCACGACCGGTTCACCGGGCATCGGCCGCAGGTCACACCCGCGGTCGGTCACACCCGCGG
GGGCGCCGGCCGTCCGGCCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MRYRKFGRTGIEVSRQCLGSMMFGVIGNPDHAACERIIARALDAGINFIDTADIYSRGESEQIVGKAIKGRRDDIVLATK
CFNPMGGDRNRRGASRRWITRAVEDSLRRLDTDYIDLFQIHRHDWNTDLEETLGALNDLVHQGKIRYLGSSTFPADWIVE
AQWAARRRNTERFVCEQPQYSIFARSVEQAVLPACRRHDIAVIPWSPLSGGWLTGKYRRGQAVPADARYAAGNVMAQGRA
VGESPESQARFDAVEQLSAVAAEAGLSLTHLALGFVESHPAITSTIIGPRTMEQLEDVLSGADVVLDAATLDAIDKIVEP
GTDFVGVRHMTGDPSLLPETRRRLATQFG

Sequences:

>Translated_349_residues
MRYRKFGRTGIEVSRQCLGSMMFGVIGNPDHAACERIIARALDAGINFIDTADIYSRGESEQIVGKAIKGRRDDIVLATK
CFNPMGGDRNRRGASRRWITRAVEDSLRRLDTDYIDLFQIHRHDWNTDLEETLGALNDLVHQGKIRYLGSSTFPADWIVE
AQWAARRRNTERFVCEQPQYSIFARSVEQAVLPACRRHDIAVIPWSPLSGGWLTGKYRRGQAVPADARYAAGNVMAQGRA
VGESPESQARFDAVEQLSAVAAEAGLSLTHLALGFVESHPAITSTIIGPRTMEQLEDVLSGADVVLDAATLDAIDKIVEP
GTDFVGVRHMTGDPSLLPETRRRLATQFG
>Mature_349_residues
MRYRKFGRTGIEVSRQCLGSMMFGVIGNPDHAACERIIARALDAGINFIDTADIYSRGESEQIVGKAIKGRRDDIVLATK
CFNPMGGDRNRRGASRRWITRAVEDSLRRLDTDYIDLFQIHRHDWNTDLEETLGALNDLVHQGKIRYLGSSTFPADWIVE
AQWAARRRNTERFVCEQPQYSIFARSVEQAVLPACRRHDIAVIPWSPLSGGWLTGKYRRGQAVPADARYAAGNVMAQGRA
VGESPESQARFDAVEQLSAVAAEAGLSLTHLALGFVESHPAITSTIIGPRTMEQLEDVLSGADVVLDAATLDAIDKIVEP
GTDFVGVRHMTGDPSLLPETRRRLATQFG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=325, Percent_Identity=34.4615384615385, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI27436962, Length=325, Percent_Identity=34.4615384615385, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI27436966, Length=325, Percent_Identity=34.1538461538462, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI27436969, Length=328, Percent_Identity=32.3170731707317, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI4504825, Length=326, Percent_Identity=32.2085889570552, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI27436971, Length=328, Percent_Identity=31.4024390243902, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI223718702, Length=315, Percent_Identity=29.2063492063492, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI41152114, Length=316, Percent_Identity=28.1645569620253, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI41327764, Length=292, Percent_Identity=28.4246575342466, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=40.1215805471125, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=30.5475504322767, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=28.2282282282282, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1788070, Length=330, Percent_Identity=32.4242424242424, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1788081, Length=182, Percent_Identity=32.967032967033, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1787674, Length=228, Percent_Identity=27.6315789473684, Blast_Score=78, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI212645785, Length=309, Percent_Identity=27.5080906148867, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=347, Percent_Identity=27.0893371757925, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323998, Length=334, Percent_Identity=29.940119760479, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6319958, Length=300, Percent_Identity=31, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319951, Length=287, Percent_Identity=29.616724738676, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322615, Length=290, Percent_Identity=28.6206896551724, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321052, Length=158, Percent_Identity=34.1772151898734, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24640980, Length=335, Percent_Identity=25.3731343283582, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI45549126, Length=335, Percent_Identity=25.3731343283582, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646155, Length=165, Percent_Identity=33.9393939393939, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=28.0542986425339, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38592; Mature: 38592

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYRKFGRTGIEVSRQCLGSMMFGVIGNPDHAACERIIARALDAGINFIDTADIYSRGES
CCCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEECHHHHHCCCH
EQIVGKAIKGRRDDIVLATKCFNPMGGDRNRRGASRRWITRAVEDSLRRLDTDYIDLFQI
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
HRHDWNTDLEETLGALNDLVHQGKIRYLGSSTFPADWIVEAQWAARRRNTERFVCEQPQY
HHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHEEECHHHHHHCCCCCEEECCCCH
SIFARSVEQAVLPACRRHDIAVIPWSPLSGGWLTGKYRRGQAVPADARYAAGNVMAQGRA
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCCCCCCCCCHHHCCCHHHCCCC
VGESPESQARFDAVEQLSAVAAEAGLSLTHLALGFVESHPAITSTIIGPRTMEQLEDVLS
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHC
GADVVLDAATLDAIDKIVEPGTDFVGVRHMTGDPSLLPETRRRLATQFG
CCHHEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRYRKFGRTGIEVSRQCLGSMMFGVIGNPDHAACERIIARALDAGINFIDTADIYSRGES
CCCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEECHHHHHCCCH
EQIVGKAIKGRRDDIVLATKCFNPMGGDRNRRGASRRWITRAVEDSLRRLDTDYIDLFQI
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
HRHDWNTDLEETLGALNDLVHQGKIRYLGSSTFPADWIVEAQWAARRRNTERFVCEQPQY
HHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHEEECHHHHHHCCCCCEEECCCCH
SIFARSVEQAVLPACRRHDIAVIPWSPLSGGWLTGKYRRGQAVPADARYAAGNVMAQGRA
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCCCCCCCCCHHHCCCHHHCCCC
VGESPESQARFDAVEQLSAVAAEAGLSLTHLALGFVESHPAITSTIIGPRTMEQLEDVLS
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHC
GADVVLDAATLDAIDKIVEPGTDFVGVRHMTGDPSLLPETRRRLATQFG
CCHHEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]