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The map label for this gene is tesB [H]

Identifier: 158313350

GI number: 158313350

Start: 1816046

End: 1816903

Strand: Direct

Name: tesB [H]

Synonym: Franean1_1512

Alternate gene names: 158313350

Gene position: 1816046-1816903 (Clockwise)

Preceding gene: 158313349

Following gene: 158313355

Centisome position: 20.22

GC content: 70.98

Gene sequence:

>858_bases
ATGACCGAACGCAAGCCCGACTTCGCGGACCTGCTGATGTTGGAGTCCGTGGACCGCGACATCTTCCGTGGTCTGTGCCA
TGACGGCGCGCCGATGCGCGCGTTCGGCGGGCAGGTCGCGGCGCAGGCCCAGGTGGCCGCCGGTCGGACTGTCGAGCCCG
ACCGGCGGATGCATTCGCTGCACGGCTATTTCCTCCGCCCCGGCCGCACCGACGCACCGATCGTGTACCTCGTCGAGCGC
ATCCGGGACGGTCGGTCGTTCACGACGCGCCGCGTCAGCGCGGTGCAGGACGGGGAGACCATCTTCTCGATGTCCGCGTC
GTTCCAGCGACCGCGCGAAGCCGACGAGACGCACCGGCTGCGTGCTCCGGACGTACCCGGGCCGGAGACGTTGCCCCGGT
GGTGGGGGCCGATCGAGGAGGCCCCCGAGTATCGGCCGTTCCTGCTGATCGACGTCCGCTCGACGACGGGCCCTCTCGGG
GGCGCCGAAGCCCGGCAGGCTGCCGCCGCGGCAGGATCGGTCGACGGGATGCCACGGCAGAGCGTCTGGGTACGGGTCGA
CCAGGTGCTGCCGGACGATCCGCTGCTGCACGTCTGCGCGCTGACGTACCTCTCCGACCTGACCCTGGCCAGCACTGCGA
GCCTGCCCTACAACGGCCTGCCGGGGCGGCTCGACATCGTCTCCCTCGACCACGCGATGTGGTTCCACCGGCCGTTCCGA
GCGGACGACTGGCTGCTGTTCGCGCAGGACAGTCCGAGCGCCGACAGCGGGAGAGGCCTCTCCCGGGGCATGTTCTTCAC
CCGGGACGGCCTGCTCGTCGCCTCCGCCATCCAGGAGGTCGGCCTGTTCCGCCGCTGA

Upstream 100 bases:

>100_bases
CCGCGAACCCGGCCGTCGAGCGGCGCACCGCCGTGACGCCGGCGAGCCGCGCGCCGCGCCGGTGTGCGACGTCCGACCTG
GTGTCTGGCGGCGGACGTCG

Downstream 100 bases:

>100_bases
GGCCCGCCCGCCGCCGGTGGGCGCCGGGTCAGCGGACGACCTCGAACACCTGCTTCTGGACACCGTTCGGGTAGGCGTCG
CATTCGACCAGTTTCAGCAT

Product: palmitoyl-CoA hydrolase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTERKPDFADLLMLESVDRDIFRGLCHDGAPMRAFGGQVAAQAQVAAGRTVEPDRRMHSLHGYFLRPGRTDAPIVYLVER
IRDGRSFTTRRVSAVQDGETIFSMSASFQRPREADETHRLRAPDVPGPETLPRWWGPIEEAPEYRPFLLIDVRSTTGPLG
GAEARQAAAAAGSVDGMPRQSVWVRVDQVLPDDPLLHVCALTYLSDLTLASTASLPYNGLPGRLDIVSLDHAMWFHRPFR
ADDWLLFAQDSPSADSGRGLSRGMFFTRDGLLVASAIQEVGLFRR

Sequences:

>Translated_285_residues
MTERKPDFADLLMLESVDRDIFRGLCHDGAPMRAFGGQVAAQAQVAAGRTVEPDRRMHSLHGYFLRPGRTDAPIVYLVER
IRDGRSFTTRRVSAVQDGETIFSMSASFQRPREADETHRLRAPDVPGPETLPRWWGPIEEAPEYRPFLLIDVRSTTGPLG
GAEARQAAAAAGSVDGMPRQSVWVRVDQVLPDDPLLHVCALTYLSDLTLASTASLPYNGLPGRLDIVSLDHAMWFHRPFR
ADDWLLFAQDSPSADSGRGLSRGMFFTRDGLLVASAIQEVGLFRR
>Mature_284_residues
TERKPDFADLLMLESVDRDIFRGLCHDGAPMRAFGGQVAAQAQVAAGRTVEPDRRMHSLHGYFLRPGRTDAPIVYLVERI
RDGRSFTTRRVSAVQDGETIFSMSASFQRPREADETHRLRAPDVPGPETLPRWWGPIEEAPEYRPFLLIDVRSTTGPLGG
AEARQAAAAAGSVDGMPRQSVWVRVDQVLPDDPLLHVCALTYLSDLTLASTASLPYNGLPGRLDIVSLDHAMWFHRPFRA
DDWLLFAQDSPSADSGRGLSRGMFFTRDGLLVASAIQEVGLFRR

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=282, Percent_Identity=37.9432624113475, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI1786657, Length=274, Percent_Identity=42.3357664233577, Blast_Score=201, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17558508, Length=302, Percent_Identity=35.7615894039735, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71988741, Length=285, Percent_Identity=36.140350877193, Blast_Score=154, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI115532456, Length=272, Percent_Identity=34.9264705882353, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17531889, Length=272, Percent_Identity=34.9264705882353, Blast_Score=133, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17531885, Length=272, Percent_Identity=34.9264705882353, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI212645202, Length=289, Percent_Identity=31.8339100346021, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71982224, Length=293, Percent_Identity=29.6928327645051, Blast_Score=107, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 31628; Mature: 31497

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERKPDFADLLMLESVDRDIFRGLCHDGAPMRAFGGQVAAQAQVAAGRTVEPDRRMHSL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCCCCHHHHHHHH
HGYFLRPGRTDAPIVYLVERIRDGRSFTTRRVSAVQDGETIFSMSASFQRPREADETHRL
CCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEHHHHHCCCCCCCHHHCC
RAPDVPGPETLPRWWGPIEEAPEYRPFLLIDVRSTTGPLGGAEARQAAAAAGSVDGMPRQ
CCCCCCCCCCCHHHCCCHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCC
SVWVRVDQVLPDDPLLHVCALTYLSDLTLASTASLPYNGLPGRLDIVSLDHAMWFHRPFR
HHEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHCCCCC
ADDWLLFAQDSPSADSGRGLSRGMFFTRDGLLVASAIQEVGLFRR
CCCEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TERKPDFADLLMLESVDRDIFRGLCHDGAPMRAFGGQVAAQAQVAAGRTVEPDRRMHSL
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCCCCHHHHHHHH
HGYFLRPGRTDAPIVYLVERIRDGRSFTTRRVSAVQDGETIFSMSASFQRPREADETHRL
CCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEHHHHHCCCCCCCHHHCC
RAPDVPGPETLPRWWGPIEEAPEYRPFLLIDVRSTTGPLGGAEARQAAAAAGSVDGMPRQ
CCCCCCCCCCCHHHCCCHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCC
SVWVRVDQVLPDDPLLHVCALTYLSDLTLASTASLPYNGLPGRLDIVSLDHAMWFHRPFR
HHEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHCCCCC
ADDWLLFAQDSPSADSGRGLSRGMFFTRDGLLVASAIQEVGLFRR
CCCEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]