Click here to switch to the map view.

The map label for this gene is gltC [H]

Identifier: 158313131

GI number: 158313131

Start: 1541703

End: 1542635

Strand: Direct

Name: gltC [H]

Synonym: Franean1_1279

Alternate gene names: 158313131

Gene position: 1541703-1542635 (Clockwise)

Preceding gene: 158313126

Following gene: 158313133

Centisome position: 17.16

GC content: 71.6

Gene sequence:

>933_bases
GTGCAGCTCCATCAGCTTGCGTATTTCGTGGCCGTGGCCGAGACCAGGCACTTCACCCGTGCGGCCGAGCGTGAGCACGT
AGCGCAGCCGTCCCTCTCGCAACAGATCCGTGCCCTGGAACAGGAGCTGGGTAGTCCCCTGTTCAACCGAATGCGGGGGA
ACATCACACTCACTCCGGCAGGGGAGACACTGCTCCCGCTGGCACGAAGGATCCTCGCCGACACCGAGACGGCCCGCCGT
CAGGTGCAGGAGCTGCTCGACCTGCGGCACGGCACCGTGCGGCTGGGCGCGACGCCGAGCCTGTGCACCGGGTTCCTGCC
CGAGGTGCTGCACGCCTTCCACCTCGACTACCCGGGCATCCGGCTGCTCGTCGAGGAGGGCGGCTCGCGCGATCTCATCC
GCGACCTGGCGCAGGGCCACCTCGACCTGGCGCTCATCATCCTTCCGCTGCACAGCTCGGACCCGGCGCTGTCGACCACG
CCGCTGCTGCGCGAGGACCTGGTCGTCGTCACGTCCGAGAACTCCCCGCCGCCGGCGCGGGACGGCCACCTCCAGGTGTC
CGACCTGCGCCACCGCCCGCTGGTGATGTTCCGCCGGGGCTACGACCTCCGGGAGTTCACCGTGAGCGCCTGCCGGGTCG
CCGGCTTCGAGCCGACCTTCGCGATCGAGGGCGGGGAGATGGACGCGGTGGTCGGCTTCGTCGAGGCCGGACTGGGTGCC
GCGGTGATCCCGAGCATGGTCGCCCGGCGTCAGCGGCTGCGTACCACCGCCTTCGCTCCGCCCGGTCTGCACCGGACGAT
CGGGCTGGCCCACCGCCGTGACGTCGAGCCGCCGCGGGCGGCCCAGGAGCTGCGGCGCAGCCTGCGGGCCTACCTGAAGA
GCACGGCTGAGGCCGGAACGCTCCCGCCGGGCACGGATCTCCTGCCCGGGTGA

Upstream 100 bases:

>100_bases
ACAGCCACGTTGGGAAACCCTAAGGACAAGTCTCCGAGTGGTCCAAGACATGATGGGCCTGATCTCGATAGGCAGTAACT
ATCGTCGGCTACCCTAAGGT

Downstream 100 bases:

>100_bases
CGCATGCCTCCCGGCGTGGATGACGTGCGTCCGCTGGCCGACGGCTCGACCTCTGAGTCACGCCTGAGGCGAGCCGGGCC
CGGCGGGGAAGATGGAGGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MQLHQLAYFVAVAETRHFTRAAEREHVAQPSLSQQIRALEQELGSPLFNRMRGNITLTPAGETLLPLARRILADTETARR
QVQELLDLRHGTVRLGATPSLCTGFLPEVLHAFHLDYPGIRLLVEEGGSRDLIRDLAQGHLDLALIILPLHSSDPALSTT
PLLREDLVVVTSENSPPPARDGHLQVSDLRHRPLVMFRRGYDLREFTVSACRVAGFEPTFAIEGGEMDAVVGFVEAGLGA
AVIPSMVARRQRLRTTAFAPPGLHRTIGLAHRRDVEPPRAAQELRRSLRAYLKSTAEAGTLPPGTDLLPG

Sequences:

>Translated_310_residues
MQLHQLAYFVAVAETRHFTRAAEREHVAQPSLSQQIRALEQELGSPLFNRMRGNITLTPAGETLLPLARRILADTETARR
QVQELLDLRHGTVRLGATPSLCTGFLPEVLHAFHLDYPGIRLLVEEGGSRDLIRDLAQGHLDLALIILPLHSSDPALSTT
PLLREDLVVVTSENSPPPARDGHLQVSDLRHRPLVMFRRGYDLREFTVSACRVAGFEPTFAIEGGEMDAVVGFVEAGLGA
AVIPSMVARRQRLRTTAFAPPGLHRTIGLAHRRDVEPPRAAQELRRSLRAYLKSTAEAGTLPPGTDLLPG
>Mature_310_residues
MQLHQLAYFVAVAETRHFTRAAEREHVAQPSLSQQIRALEQELGSPLFNRMRGNITLTPAGETLLPLARRILADTETARR
QVQELLDLRHGTVRLGATPSLCTGFLPEVLHAFHLDYPGIRLLVEEGGSRDLIRDLAQGHLDLALIILPLHSSDPALSTT
PLLREDLVVVTSENSPPPARDGHLQVSDLRHRPLVMFRRGYDLREFTVSACRVAGFEPTFAIEGGEMDAVVGFVEAGLGA
AVIPSMVARRQRLRTTAFAPPGLHRTIGLAHRRDVEPPRAAQELRRSLRAYLKSTAEAGTLPPGTDLLPG

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=279, Percent_Identity=33.6917562724014, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=30.0724637681159, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787879, Length=257, Percent_Identity=33.0739299610895, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787530, Length=248, Percent_Identity=27.4193548387097, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI145693105, Length=276, Percent_Identity=24.6376811594203, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787806, Length=244, Percent_Identity=31.1475409836066, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788887, Length=176, Percent_Identity=36.9318181818182, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788297, Length=263, Percent_Identity=28.8973384030418, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=28.6290322580645, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=27.9352226720648, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI48994962, Length=141, Percent_Identity=36.1702127659575, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=27.5167785234899, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787601, Length=176, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788748, Length=244, Percent_Identity=24.5901639344262, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081904, Length=180, Percent_Identity=34.4444444444444, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790262, Length=301, Percent_Identity=26.578073089701, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786401, Length=170, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787589, Length=128, Percent_Identity=33.59375, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34080; Mature: 34080

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLHQLAYFVAVAETRHFTRAAEREHVAQPSLSQQIRALEQELGSPLFNRMRGNITLTPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHCCCEEECCC
GETLLPLARRILADTETARRQVQELLDLRHGTVRLGATPSLCTGFLPEVLHAFHLDYPGI
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCE
RLLVEEGGSRDLIRDLAQGHLDLALIILPLHSSDPALSTTPLLREDLVVVTSENSPPPAR
EEEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHCCEEEEECCCCCCCCC
DGHLQVSDLRHRPLVMFRRGYDLREFTVSACRVAGFEPTFAIEGGEMDAVVGFVEAGLGA
CCCEEHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCH
AVIPSMVARRQRLRTTAFAPPGLHRTIGLAHRRDVEPPRAAQELRRSLRAYLKSTAEAGT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
LPPGTDLLPG
CCCCCCCCCC
>Mature Secondary Structure
MQLHQLAYFVAVAETRHFTRAAEREHVAQPSLSQQIRALEQELGSPLFNRMRGNITLTPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHCCCEEECCC
GETLLPLARRILADTETARRQVQELLDLRHGTVRLGATPSLCTGFLPEVLHAFHLDYPGI
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCE
RLLVEEGGSRDLIRDLAQGHLDLALIILPLHSSDPALSTTPLLREDLVVVTSENSPPPAR
EEEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHCCEEEEECCCCCCCCC
DGHLQVSDLRHRPLVMFRRGYDLREFTVSACRVAGFEPTFAIEGGEMDAVVGFVEAGLGA
CCCEEHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCH
AVIPSMVARRQRLRTTAFAPPGLHRTIGLAHRRDVEPPRAAQELRRSLRAYLKSTAEAGT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
LPPGTDLLPG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]