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The map label for this gene is coaD

Identifier: 158312986

GI number: 158312986

Start: 1355466

End: 1355954

Strand: Direct

Name: coaD

Synonym: Franean1_1134

Alternate gene names: 158312986

Gene position: 1355466-1355954 (Clockwise)

Preceding gene: 158312985

Following gene: 158312987

Centisome position: 15.09

GC content: 62.37

Gene sequence:

>489_bases
ATGAGGAGGGCAGTCTGTCCCGGATCGTTCGACCCCATCACCAACGGTCACCTCGACATCATCGTCAGAGCGAGCAAGCT
CTTCGACGAGGTCGTCGTCGCCGTTCTGATCAATAAATCGAAGGCCCATCTGTTCACGATCGAAGAACGGATCGACCTCA
TCCGGGATGCGGTGCGCAGCCATCCCGACGCACCCACCAACGTCGTAGTGGACTCGTCGCACGGCCTGCTGGTCGACTTC
TGTCGGGTGCGCGGCATCCAGTCCATTGTCAAGGGCCTGCGGGCCGTCAGTGATTTCGACTACGAGCTGCAGATGGCACA
GATGAACCACTCGCTGGCCGGAGTGGAGACCCTGTTCATGAGTACGAACCCGCAGTACGCGTTCCTCTCCTCGAGCCTTG
TCAAGGAAGTCGCCCGCTACGGCGGCGACGTCTCCGGGCTGGTGCCGGACGTCGTCCTCAAGGGCCTGCGGGACCGCTCC
GCGCCCTAG

Upstream 100 bases:

>100_bases
AGCGCGCGTACCGGAGCGGTCCCGTGACCTGGCCGGACGGCCTCATAGCACTGCGTGAGCGCAGGTACGGAGAGGGGGTC
CTCTGGTACGGTAATCGATC

Downstream 100 bases:

>100_bases
TCGCCCGAGTGCGGACCGATCGCCGGCGGCACCCCTGTGGGCGCCGCCGGCGGGCGTCTGCCATCAAGTGGTTGTTGTGT
TTCTGTTGTGATGGCGTGTG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MRRAVCPGSFDPITNGHLDIIVRASKLFDEVVVAVLINKSKAHLFTIEERIDLIRDAVRSHPDAPTNVVVDSSHGLLVDF
CRVRGIQSIVKGLRAVSDFDYELQMAQMNHSLAGVETLFMSTNPQYAFLSSSLVKEVARYGGDVSGLVPDVVLKGLRDRS
AP

Sequences:

>Translated_162_residues
MRRAVCPGSFDPITNGHLDIIVRASKLFDEVVVAVLINKSKAHLFTIEERIDLIRDAVRSHPDAPTNVVVDSSHGLLVDF
CRVRGIQSIVKGLRAVSDFDYELQMAQMNHSLAGVETLFMSTNPQYAFLSSSLVKEVARYGGDVSGLVPDVVLKGLRDRS
AP
>Mature_162_residues
MRRAVCPGSFDPITNGHLDIIVRASKLFDEVVVAVLINKSKAHLFTIEERIDLIRDAVRSHPDAPTNVVVDSSHGLLVDF
CRVRGIQSIVKGLRAVSDFDYELQMAQMNHSLAGVETLFMSTNPQYAFLSSSLVKEVARYGGDVSGLVPDVVLKGLRDRS
AP

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=161, Percent_Identity=43.4782608695652, Blast_Score=143, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_FRASN (A8L588)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001505494.1
- ProteinModelPortal:   A8L588
- SMR:   A8L588
- GeneID:   5669547
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_1134
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   FSP1855:FRANEAN1_1134-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17778; Mature: 17778

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAVCPGSFDPITNGHLDIIVRASKLFDEVVVAVLINKSKAHLFTIEERIDLIRDAVRS
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHC
HPDAPTNVVVDSSHGLLVDFCRVRGIQSIVKGLRAVSDFDYELQMAQMNHSLAGVETLFM
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHEE
STNPQYAFLSSSLVKEVARYGGDVSGLVPDVVLKGLRDRSAP
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRRAVCPGSFDPITNGHLDIIVRASKLFDEVVVAVLINKSKAHLFTIEERIDLIRDAVRS
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHC
HPDAPTNVVVDSSHGLLVDFCRVRGIQSIVKGLRAVSDFDYELQMAQMNHSLAGVETLFM
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHEE
STNPQYAFLSSSLVKEVARYGGDVSGLVPDVVLKGLRDRSAP
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA