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The map label for this gene is yqeF [C]

Identifier: 158312898

GI number: 158312898

Start: 1223889

End: 1225073

Strand: Direct

Name: yqeF [C]

Synonym: Franean1_1044

Alternate gene names: 158312898

Gene position: 1223889-1225073 (Clockwise)

Preceding gene: 158312897

Following gene: 158312899

Centisome position: 13.63

GC content: 72.41

Gene sequence:

>1185_bases
ATGCCTGGTTCTGTCATCGTGGCCGGTGCGCGCACCCCGATCGGCAAGCTCTCCGGCGCCCTCAAGGACTTCACCGCGGT
CGACCTGGGCGGTATCGCCATCCGCGCCGCGCTCGAGCGGGCCGGGCTGGCCGGCGACGCCGTCGACTACGTCATCCTGG
GCCAGGTCATCCAGGCCGGCGCCGGCCAGGCCGCCGCCCGCCAGGCCGCCGTGAAGGGCGGCATCCCGATGACGGTGCCG
TCCACCAGCATCAACAAGGTGTGCCTGTCGGGCCTGAACGCCATCTCGCTGGCGGACCTCTACATCTCCAGCGGTCAGTA
CGACGTCATCGTGGCCGGTGGCATGGAGTCGATGACCCGCGCGCCGCACCTGCTGCCCGCGCTGCGCGGCGGCGTCAAGT
ACGGCGACACCACCCTGACGGACTCGATCGCGGTGGATGCCCTCACCTGCGGGTTCGACCAGGTGTCGATGGGTCTCGCG
ACAGACCGGTACAACTCCCGCTACGGCATCACCCGCGAGGAGCAGGACGAGTTCAGCGCCCGGTCGCATCAGCGGGCCGC
GGCCGCGGCGAAGAACGGCCTGTTCGAGAACGAGATCGTCCCGGTCGAGGTGCCCCAGCGCCGCGGCGACCCGATCGTCG
TCAGCGCGGACGAGGGCGTCCGGGCCGAGACGACCGCGGAGAGCCTGGCGAAGCTGCGCCCGGCGTTCGACAAGGCCGGC
TCGATCACCGCCGGCTCGGCCTCCCAGATCTCGGACGGCGCGGCCGCGGTCGTCGTGACGAGCCGGGCGAAGGCCGAGGA
GCTGGGCCTGCCGATCATCGCCGAGGTCGGCCACCACGGTTACGTGTCCGGCCCGGACCCGTCCCTGCACTCCCAGCCGT
CGAACGCGATCCTCGCGGCCCTGGCGAAGGAGAAGCTGACCCCGGCCGACCTCGACCTCGTCGAGATCAACGAGGCGTTC
GCGGCCGTCGGCATCCAGTCGATGCGCGAGCTGGGGATCGGCCCGGACATCACCAACGTCAACGGCGGCGCGATCGCGGT
CGGCCACCCGGTTGGGATGTCTGGCACCCGGGTCGCGCTCACCCTCCTGCTCGAGCTGCAGCGCCGCGGCGGCGGCATCG
GCGCGGCGGCGCTGTGCGGCGGCGGCGGCCAGGGCGACGCCCTGGTGCTGCGCGTTCCGGCGTGA

Upstream 100 bases:

>100_bases
GGTCGCGGCACATCGCGGGGGTAGCCTCGCGGCACATCGCGGGGGTAACCGTGCAGGGCCGGTGCCGCGCGAGCCGGTAC
CCGTGACCTAGGAGGCGTCC

Downstream 100 bases:

>100_bases
GCTCGGGCTCCGGCGTGAGCGCGGGCTCCGCCGGGGTCGCTCCAGCCGGGCCGGCGAGATCCGGGCCGGCGATAGCCGGG
CGGGCGCGCGCCGCGCGCCC

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MPGSVIVAGARTPIGKLSGALKDFTAVDLGGIAIRAALERAGLAGDAVDYVILGQVIQAGAGQAAARQAAVKGGIPMTVP
STSINKVCLSGLNAISLADLYISSGQYDVIVAGGMESMTRAPHLLPALRGGVKYGDTTLTDSIAVDALTCGFDQVSMGLA
TDRYNSRYGITREEQDEFSARSHQRAAAAAKNGLFENEIVPVEVPQRRGDPIVVSADEGVRAETTAESLAKLRPAFDKAG
SITAGSASQISDGAAAVVVTSRAKAEELGLPIIAEVGHHGYVSGPDPSLHSQPSNAILAALAKEKLTPADLDLVEINEAF
AAVGIQSMRELGIGPDITNVNGGAIAVGHPVGMSGTRVALTLLLELQRRGGGIGAAALCGGGGQGDALVLRVPA

Sequences:

>Translated_394_residues
MPGSVIVAGARTPIGKLSGALKDFTAVDLGGIAIRAALERAGLAGDAVDYVILGQVIQAGAGQAAARQAAVKGGIPMTVP
STSINKVCLSGLNAISLADLYISSGQYDVIVAGGMESMTRAPHLLPALRGGVKYGDTTLTDSIAVDALTCGFDQVSMGLA
TDRYNSRYGITREEQDEFSARSHQRAAAAAKNGLFENEIVPVEVPQRRGDPIVVSADEGVRAETTAESLAKLRPAFDKAG
SITAGSASQISDGAAAVVVTSRAKAEELGLPIIAEVGHHGYVSGPDPSLHSQPSNAILAALAKEKLTPADLDLVEINEAF
AAVGIQSMRELGIGPDITNVNGGAIAVGHPVGMSGTRVALTLLLELQRRGGGIGAAALCGGGGQGDALVLRVPA
>Mature_393_residues
PGSVIVAGARTPIGKLSGALKDFTAVDLGGIAIRAALERAGLAGDAVDYVILGQVIQAGAGQAAARQAAVKGGIPMTVPS
TSINKVCLSGLNAISLADLYISSGQYDVIVAGGMESMTRAPHLLPALRGGVKYGDTTLTDSIAVDALTCGFDQVSMGLAT
DRYNSRYGITREEQDEFSARSHQRAAAAAKNGLFENEIVPVEVPQRRGDPIVVSADEGVRAETTAESLAKLRPAFDKAGS
ITAGSASQISDGAAAVVVTSRAKAEELGLPIIAEVGHHGYVSGPDPSLHSQPSNAILAALAKEKLTPADLDLVEINEAFA
AVGIQSMRELGIGPDITNVNGGAIAVGHPVGMSGTRVALTLLLELQRRGGGIGAAALCGGGGQGDALVLRVPA

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=390, Percent_Identity=44.3589743589744, Blast_Score=291, Evalue=6e-79,
Organism=Homo sapiens, GI167614485, Length=398, Percent_Identity=40.4522613065327, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI4501853, Length=398, Percent_Identity=40.7035175879397, Blast_Score=248, Evalue=8e-66,
Organism=Homo sapiens, GI4557237, Length=388, Percent_Identity=37.1134020618557, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI4504327, Length=421, Percent_Identity=32.3040380047506, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI194353979, Length=246, Percent_Identity=34.5528455284553, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI87082165, Length=391, Percent_Identity=45.7800511508951, Blast_Score=316, Evalue=1e-87,
Organism=Escherichia coli, GI1788554, Length=394, Percent_Identity=46.9543147208122, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1787663, Length=399, Percent_Identity=39.3483709273183, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI48994986, Length=398, Percent_Identity=39.1959798994975, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1788683, Length=406, Percent_Identity=29.8029556650246, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI25147385, Length=388, Percent_Identity=38.9175257731959, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI133906874, Length=389, Percent_Identity=38.8174807197943, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17535921, Length=388, Percent_Identity=37.1134020618557, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17551802, Length=425, Percent_Identity=31.2941176470588, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17535917, Length=391, Percent_Identity=30.9462915601023, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6325229, Length=390, Percent_Identity=40.2564102564103, Blast_Score=272, Evalue=8e-74,
Organism=Saccharomyces cerevisiae, GI6322031, Length=392, Percent_Identity=36.734693877551, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24655093, Length=390, Percent_Identity=44.6153846153846, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24640423, Length=387, Percent_Identity=38.7596899224806, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI17648125, Length=391, Percent_Identity=36.3171355498721, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17137578, Length=425, Percent_Identity=32.7058823529412, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 39971; Mature: 39840

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGSVIVAGARTPIGKLSGALKDFTAVDLGGIAIRAALERAGLAGDAVDYVILGQVIQAG
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
AGQAAARQAAVKGGIPMTVPSTSINKVCLSGLNAISLADLYISSGQYDVIVAGGMESMTR
CCHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCHHEEEEEEECCCCEEEEEECCHHHHHH
APHLLPALRGGVKYGDTTLTDSIAVDALTCGFDQVSMGLATDRYNSRYGITREEQDEFSA
CCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCEECCCCCCCCCCCCCHHHHHH
RSHQRAAAAAKNGLFENEIVPVEVPQRRGDPIVVSADEGVRAETTAESLAKLRPAFDKAG
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
SITAGSASQISDGAAAVVVTSRAKAEELGLPIIAEVGHHGYVSGPDPSLHSQPSNAILAA
CEECCCHHHCCCCCEEEEEECCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHH
LAKEKLTPADLDLVEINEAFAAVGIQSMRELGIGPDITNVNGGAIAVGHPVGMSGTRVAL
HHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHH
TLLLELQRRGGGIGAAALCGGGGQGDALVLRVPA
HHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECC
>Mature Secondary Structure 
PGSVIVAGARTPIGKLSGALKDFTAVDLGGIAIRAALERAGLAGDAVDYVILGQVIQAG
CCCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
AGQAAARQAAVKGGIPMTVPSTSINKVCLSGLNAISLADLYISSGQYDVIVAGGMESMTR
CCHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCHHEEEEEEECCCCEEEEEECCHHHHHH
APHLLPALRGGVKYGDTTLTDSIAVDALTCGFDQVSMGLATDRYNSRYGITREEQDEFSA
CCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCEECCCCCCCCCCCCCHHHHHH
RSHQRAAAAAKNGLFENEIVPVEVPQRRGDPIVVSADEGVRAETTAESLAKLRPAFDKAG
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
SITAGSASQISDGAAAVVVTSRAKAEELGLPIIAEVGHHGYVSGPDPSLHSQPSNAILAA
CEECCCHHHCCCCCEEEEEECCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHH
LAKEKLTPADLDLVEINEAFAAVGIQSMRELGIGPDITNVNGGAIAVGHPVGMSGTRVAL
HHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHH
TLLLELQRRGGGIGAAALCGGGGQGDALVLRVPA
HHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA