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The map label for this gene is moeZ [H]

Identifier: 158312776

GI number: 158312776

Start: 1072870

End: 1074042

Strand: Direct

Name: moeZ [H]

Synonym: Franean1_0922

Alternate gene names: 158312776

Gene position: 1072870-1074042 (Clockwise)

Preceding gene: 158312775

Following gene: 158312777

Centisome position: 11.94

GC content: 69.22

Gene sequence:

>1173_bases
GTGTCACTACCGCCCCTGGTCTCCCCCGCCGAGGGGCTGACCGTCGACGAGGTCCGCCGGTACTCGCGGCATCTGATCAT
TCCCGACGTCGCGATGGACGGGCAGAAGCGCCTGAAGAACGCGAAGGTCCTTGCCGTGGGTGCGGGTGGCCTGGGCTCGC
CGACCCTGATGTACCTGGCCGCGGCCGGGGTGGGGACGCTGGGCATCGTCGAGTTCGACGTGGTGGACGAGTCGAATCTG
CAGCGCCAGATCATCCACGGGCAGTCCGACGTCGGCCGGAGCAAGGCCGAGTCCGCCCGCGACTCCGTCCGGGAGATCAA
CCCGCTGGTCAACGTGGTGATCCACGAGACCCGGCTGGACACCTCCAACGTGATGGAGATCTTCGCCCAGTACGACCTGA
TCGTCGACGGCACCGACAACTTCGCGACCCGCTACCTGGTCAACGACGCCTGCGTGCTGCTCGGCAAGCCCTACGTGTGG
GGTTCCATCTACCGGTTCGACGGTCAGGCGAGCGTCTTCTGGGCCGAGCACGGCCCGTGTTACCGGTGCCTCTACCCTGA
GCCGCCTCCGCCGGGCATGGTCCCCTCGTGCGCCGAGGGCGGTGTCCTCGGTGTGCTCTGCGCCTCCATCGGGTCGATCC
AGACCACGGAGGCCATCAAGGTGCTGACCGGAGTGGGCGACCCGCTCGTCGGCCGGCTGATGGTCTACGACGCCCTGGAG
ATGTCCTACCGGACGATCAAGGTGCGCAAGGACCCGGAGTGCCCGCTGTGCGGGAAGAACCCGTCGATCACCGAGCTCAT
CGACTACGAGGCGTTCTGCGGCGTGGTCTCCGAGGAGGCCCAGCTCGCGGCGGCCGGCTCCACGATCACCGCCGCCGAGC
TGAGGACCATGCTGGACGGCGGCGAGCCGATCGAGCTGATCGACGTCCGTGAGCCCGCGGAGTGGGAGATCGTGCGGATC
CCCGGCGCGCGCCTCATCCCGAAGGGGGAGCTGCCGGCGCACCTGGCCGAGCTGCCCCAGGACCGGCGGGTCGTCGTCTA
CTGCAAGAGCGGGGTGCGCTCAGCCGAGGCCCTCGCGACCCTCAAGGGCGCCGGCTTCGCCACCGCCGTCCACGTCCAGG
GTGGCGTGACCGCCTGGGCCACCCAGGTGGACAAGACCCTCCCCGTCTACTGA

Upstream 100 bases:

>100_bases
TCGGTGGGCTGTCGGCGGTCGCGCGAACCGCCGATCACGGCTGCCGGACCGGGCGGCTGTGGCATCGTCGGGTGGTACGA
CAGAGAAGGCGAGGAGCAAC

Downstream 100 bases:

>100_bases
TCCGGCTTTCCGGCCGTCGGACCGCAGCGTGTCCCCGGGGTGTCCCCGGGCCTGCGCTCGGAAGATCCGTGGCGGGTGGG
TGCGTTCGCCACGGGCGCAC

Product: molybdopterin biosynthesis-like protein MoeZ

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSLPPLVSPAEGLTVDEVRRYSRHLIIPDVAMDGQKRLKNAKVLAVGAGGLGSPTLMYLAAAGVGTLGIVEFDVVDESNL
QRQIIHGQSDVGRSKAESARDSVREINPLVNVVIHETRLDTSNVMEIFAQYDLIVDGTDNFATRYLVNDACVLLGKPYVW
GSIYRFDGQASVFWAEHGPCYRCLYPEPPPPGMVPSCAEGGVLGVLCASIGSIQTTEAIKVLTGVGDPLVGRLMVYDALE
MSYRTIKVRKDPECPLCGKNPSITELIDYEAFCGVVSEEAQLAAAGSTITAAELRTMLDGGEPIELIDVREPAEWEIVRI
PGARLIPKGELPAHLAELPQDRRVVVYCKSGVRSAEALATLKGAGFATAVHVQGGVTAWATQVDKTLPVY

Sequences:

>Translated_390_residues
MSLPPLVSPAEGLTVDEVRRYSRHLIIPDVAMDGQKRLKNAKVLAVGAGGLGSPTLMYLAAAGVGTLGIVEFDVVDESNL
QRQIIHGQSDVGRSKAESARDSVREINPLVNVVIHETRLDTSNVMEIFAQYDLIVDGTDNFATRYLVNDACVLLGKPYVW
GSIYRFDGQASVFWAEHGPCYRCLYPEPPPPGMVPSCAEGGVLGVLCASIGSIQTTEAIKVLTGVGDPLVGRLMVYDALE
MSYRTIKVRKDPECPLCGKNPSITELIDYEAFCGVVSEEAQLAAAGSTITAAELRTMLDGGEPIELIDVREPAEWEIVRI
PGARLIPKGELPAHLAELPQDRRVVVYCKSGVRSAEALATLKGAGFATAVHVQGGVTAWATQVDKTLPVY
>Mature_389_residues
SLPPLVSPAEGLTVDEVRRYSRHLIIPDVAMDGQKRLKNAKVLAVGAGGLGSPTLMYLAAAGVGTLGIVEFDVVDESNLQ
RQIIHGQSDVGRSKAESARDSVREINPLVNVVIHETRLDTSNVMEIFAQYDLIVDGTDNFATRYLVNDACVLLGKPYVWG
SIYRFDGQASVFWAEHGPCYRCLYPEPPPPGMVPSCAEGGVLGVLCASIGSIQTTEAIKVLTGVGDPLVGRLMVYDALEM
SYRTIKVRKDPECPLCGKNPSITELIDYEAFCGVVSEEAQLAAAGSTITAAELRTMLDGGEPIELIDVREPAEWEIVRIP
GARLIPKGELPAHLAELPQDRRVVVYCKSGVRSAEALATLKGAGFATAVHVQGGVTAWATQVDKTLPVY

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=410, Percent_Identity=39.5121951219512, Blast_Score=278, Evalue=6e-75,
Organism=Homo sapiens, GI4885649, Length=148, Percent_Identity=33.7837837837838, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI38045942, Length=176, Percent_Identity=31.25, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI38045944, Length=176, Percent_Identity=31.25, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI23510338, Length=174, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI23510340, Length=174, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI38045948, Length=148, Percent_Identity=32.4324324324324, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=41.5322580645161, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87082356, Length=245, Percent_Identity=38.7755102040816, Blast_Score=172, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17540406, Length=395, Percent_Identity=40.7594936708861, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI193203301, Length=166, Percent_Identity=29.5180722891566, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71984476, Length=174, Percent_Identity=32.7586206896552, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6321903, Length=404, Percent_Identity=38.6138613861386, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6320598, Length=170, Percent_Identity=30.5882352941176, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322639, Length=190, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325438, Length=125, Percent_Identity=29.6, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582879, Length=400, Percent_Identity=42.5, Blast_Score=317, Evalue=6e-87,
Organism=Drosophila melanogaster, GI24660640, Length=150, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI20129973, Length=171, Percent_Identity=28.6549707602339, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573937, Length=201, Percent_Identity=26.3681592039801, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 41917; Mature: 41785

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPPLVSPAEGLTVDEVRRYSRHLIIPDVAMDGQKRLKNAKVLAVGAGGLGSPTLMYLA
CCCCCCCCCCCCCCHHHHHHHHCEEEECCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHH
AAGVGTLGIVEFDVVDESNLQRQIIHGQSDVGRSKAESARDSVREINPLVNVVIHETRLD
HCCCCEEEEEEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCC
TSNVMEIFAQYDLIVDGTDNFATRYLVNDACVLLGKPYVWGSIYRFDGQASVFWAEHGPC
HHHHHHHHHHCCEEEECCCCCEEEHHHCCEEEEECCCCEEEEEEEECCCEEEEEECCCCE
YRCLYPEPPPPGMVPSCAEGGVLGVLCASIGSIQTTEAIKVLTGVGDPLVGRLMVYDALE
EEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
MSYRTIKVRKDPECPLCGKNPSITELIDYEAFCGVVSEEAQLAAAGSTITAAELRTMLDG
CCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHCCCHHEEECCCEEHHHHHHHHHCC
GEPIELIDVREPAEWEIVRIPGARLIPKGELPAHLAELPQDRRVVVYCKSGVRSAEALAT
CCCEEEEECCCCCCEEEEECCCCEECCCCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHH
LKGAGFATAVHVQGGVTAWATQVDKTLPVY
HCCCCEEEEEEECCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SLPPLVSPAEGLTVDEVRRYSRHLIIPDVAMDGQKRLKNAKVLAVGAGGLGSPTLMYLA
CCCCCCCCCCCCCHHHHHHHHCEEEECCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHH
AAGVGTLGIVEFDVVDESNLQRQIIHGQSDVGRSKAESARDSVREINPLVNVVIHETRLD
HCCCCEEEEEEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCC
TSNVMEIFAQYDLIVDGTDNFATRYLVNDACVLLGKPYVWGSIYRFDGQASVFWAEHGPC
HHHHHHHHHHCCEEEECCCCCEEEHHHCCEEEEECCCCEEEEEEEECCCEEEEEECCCCE
YRCLYPEPPPPGMVPSCAEGGVLGVLCASIGSIQTTEAIKVLTGVGDPLVGRLMVYDALE
EEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
MSYRTIKVRKDPECPLCGKNPSITELIDYEAFCGVVSEEAQLAAAGSTITAAELRTMLDG
CCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHCCCHHEEECCCEEHHHHHHHHHCC
GEPIELIDVREPAEWEIVRIPGARLIPKGELPAHLAELPQDRRVVVYCKSGVRSAEALAT
CCCEEEEECCCCCCEEEEECCCCEECCCCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHH
LKGAGFATAVHVQGGVTAWATQVDKTLPVY
HCCCCEEEEEEECCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]