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The map label for this gene is xseA

Identifier: 158312702

GI number: 158312702

Start: 992499

End: 993704

Strand: Direct

Name: xseA

Synonym: Franean1_0846

Alternate gene names: 158312702

Gene position: 992499-993704 (Clockwise)

Preceding gene: 158312698

Following gene: 158312703

Centisome position: 11.05

GC content: 73.38

Gene sequence:

>1206_bases
GTGCCCCTGACCTCGACCCCGGACGAGCCGCTCCCAGTGCGGACGATCTCCCGGGCGTTGGGTGACTGGATCTCCCGGCT
CGGTCGCGTATGGGTGGAAGGTCAGGTCACCGAGATCTCCCGCCGGCCGGGCATGAACACGGTCTTCCTCACCCTGCGCG
ACCCCGTCGCGGACGTCTCCCTACGGGTCACCTGCCCCCGGGCGGTGTGCGACGCGGTCGGTCCCGGGCTCGTCGACGGG
GCCCGGGTGGTGGTCTGGGGCAAGCCCAGCTTCCACCCCGGCCGGGGCACGTTGGCCCTTGCTGTAGTGGAGATTCGCCC
TCTAGGGGCCGGTGCGCTGCTGGCCCGGCTGGAGCGGCTGAAGGCCACGCTCGCCGCCGAGGGACTCTTCGCGGCGAGCC
GCAAACGGCGGCTCCCGTTCCTCCCGACGGCGGTCGGCCTCATCACCGGGCGTGCATCCGCCGCCGAGCGCGACGTGATC
GAGAACGCCCGCCGCCGGTGGCCCGCGGTACGCATCGAACTACGGGAGGTGGCGGTCCAGGGTCCCCTCGCGGTGAGCCA
GATCCTCGACGCGCTGTCCGATCTGGACGCCGACCGCGCCGTCGAGGTGATCGTCATCGCCCGCGGCGGGGGCTCCCTGG
AAGATCTCCTACCGTTCTCGGACGAGGCCCTGCTGCGCGCCGTTGTCGCCGCCCGGACACCTGTCGTGTCGGCAATCGGA
CACGAGCAGGACACCCCCCTGCTCGACTTTGTGGCCGACGTCCGAGCCTCCACGCCGACCGACGCCGCCAAACGTGTGGT
CCCCGACGTCTCCGAGCAGTCAGCGCTGGTGGAGGCCCTGCGCAGCCGGGCCCGCAGGGTCCTCGCACACCGCCTCGACC
TCGAACGACGCCGGCTGGCGGACCTGCGGGCCCGTCCCGTCCTGGCAGCCCCGCTGCGCGAGATCGACCGGCGCGAGCAG
ACCGTCGGGGCGCTGCGCTCGCGCTCGCTGCGCTGCCTCACCCACGCGGTGGACGTCGCCGAGCGCGACCTCGTCCACGC
GGCGGCGCGCATGCGGGCGCTGTCCCCGGCGGCCACGCTGGAACGCGGCTACGCCCTGATCCAGAACGCGGACGGCGCGG
TGATCCGCTCACCAGCCGAGATCGAGGCCGGCGACCCGCTAACCGTCCGGGTCGCGGGCGGTACCTTCGCCGCCAGAGCG
GAGTGA

Upstream 100 bases:

>100_bases
GCGAGGCTGGAAGAGCGGCGAGCGGAGCATCACCGGATGGGCACCATCGTCCGGCCCGCCGGTGACCTTCCCCCGTGGGG
GGAGGTCGTACGGTTCGGAG

Downstream 100 bases:

>100_bases
CCACCACGCGGCTCTCGAACGGTTCTCCCGGCGTTCCTGGCGCTCCCGGGCCCGGGAGCGTGCTCACGGCCGTCGAACGG
GACAGCCGTCGAACGGGACA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MPLTSTPDEPLPVRTISRALGDWISRLGRVWVEGQVTEISRRPGMNTVFLTLRDPVADVSLRVTCPRAVCDAVGPGLVDG
ARVVVWGKPSFHPGRGTLALAVVEIRPLGAGALLARLERLKATLAAEGLFAASRKRRLPFLPTAVGLITGRASAAERDVI
ENARRRWPAVRIELREVAVQGPLAVSQILDALSDLDADRAVEVIVIARGGGSLEDLLPFSDEALLRAVVAARTPVVSAIG
HEQDTPLLDFVADVRASTPTDAAKRVVPDVSEQSALVEALRSRARRVLAHRLDLERRRLADLRARPVLAAPLREIDRREQ
TVGALRSRSLRCLTHAVDVAERDLVHAAARMRALSPAATLERGYALIQNADGAVIRSPAEIEAGDPLTVRVAGGTFAARA
E

Sequences:

>Translated_401_residues
MPLTSTPDEPLPVRTISRALGDWISRLGRVWVEGQVTEISRRPGMNTVFLTLRDPVADVSLRVTCPRAVCDAVGPGLVDG
ARVVVWGKPSFHPGRGTLALAVVEIRPLGAGALLARLERLKATLAAEGLFAASRKRRLPFLPTAVGLITGRASAAERDVI
ENARRRWPAVRIELREVAVQGPLAVSQILDALSDLDADRAVEVIVIARGGGSLEDLLPFSDEALLRAVVAARTPVVSAIG
HEQDTPLLDFVADVRASTPTDAAKRVVPDVSEQSALVEALRSRARRVLAHRLDLERRRLADLRARPVLAAPLREIDRREQ
TVGALRSRSLRCLTHAVDVAERDLVHAAARMRALSPAATLERGYALIQNADGAVIRSPAEIEAGDPLTVRVAGGTFAARA
E
>Mature_400_residues
PLTSTPDEPLPVRTISRALGDWISRLGRVWVEGQVTEISRRPGMNTVFLTLRDPVADVSLRVTCPRAVCDAVGPGLVDGA
RVVVWGKPSFHPGRGTLALAVVEIRPLGAGALLARLERLKATLAAEGLFAASRKRRLPFLPTAVGLITGRASAAERDVIE
NARRRWPAVRIELREVAVQGPLAVSQILDALSDLDADRAVEVIVIARGGGSLEDLLPFSDEALLRAVVAARTPVVSAIGH
EQDTPLLDFVADVRASTPTDAAKRVVPDVSEQSALVEALRSRARRVLAHRLDLERRRLADLRARPVLAAPLREIDRREQT
VGALRSRSLRCLTHAVDVAERDLVHAAARMRALSPAATLERGYALIQNADGAVIRSPAEIEAGDPLTVRVAGGTFAARAE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=413, Percent_Identity=30.7506053268765, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_FRASN (A8L188)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001505210.1
- GeneID:   5669262
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_0846
- HOGENOM:   HBG634411
- OMA:   RLLIANM
- ProtClustDB:   PRK00286
- BioCyc:   FSP1855:FRANEAN1_0846-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 43124; Mature: 42993

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTSTPDEPLPVRTISRALGDWISRLGRVWVEGQVTEISRRPGMNTVFLTLRDPVADVS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHCCCCCCEEEEEECCCCCCCE
LRVTCPRAVCDAVGPGLVDGARVVVWGKPSFHPGRGTLALAVVEIRPLGAGALLARLERL
EEEECCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHH
KATLAAEGLFAASRKRRLPFLPTAVGLITGRASAAERDVIENARRRWPAVRIELREVAVQ
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEEHHHHHHC
GPLAVSQILDALSDLDADRAVEVIVIARGGGSLEDLLPFSDEALLRAVVAARTPVVSAIG
CCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHCHHHHHHC
HEQDTPLLDFVADVRASTPTDAAKRVVPDVSEQSALVEALRSRARRVLAHRLDLERRRLA
CCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRARPVLAAPLREIDRREQTVGALRSRSLRCLTHAVDVAERDLVHAAARMRALSPAATL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ERGYALIQNADGAVIRSPAEIEAGDPLTVRVAGGTFAARAE
HHCHHEEECCCCCEEECCCCCCCCCCEEEEEECCCEECCCC
>Mature Secondary Structure 
PLTSTPDEPLPVRTISRALGDWISRLGRVWVEGQVTEISRRPGMNTVFLTLRDPVADVS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHCCCCCCEEEEEECCCCCCCE
LRVTCPRAVCDAVGPGLVDGARVVVWGKPSFHPGRGTLALAVVEIRPLGAGALLARLERL
EEEECCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHH
KATLAAEGLFAASRKRRLPFLPTAVGLITGRASAAERDVIENARRRWPAVRIELREVAVQ
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEEHHHHHHC
GPLAVSQILDALSDLDADRAVEVIVIARGGGSLEDLLPFSDEALLRAVVAARTPVVSAIG
CCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHCHHHHHHC
HEQDTPLLDFVADVRASTPTDAAKRVVPDVSEQSALVEALRSRARRVLAHRLDLERRRLA
CCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRARPVLAAPLREIDRREQTVGALRSRSLRCLTHAVDVAERDLVHAAARMRALSPAATL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ERGYALIQNADGAVIRSPAEIEAGDPLTVRVAGGTFAARAE
HHCHHEEECCCCCEEECCCCCCCCCCEEEEEECCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA