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The map label for this gene is moaCB [H]

Identifier: 158312548

GI number: 158312548

Start: 810356

End: 810919

Strand: Direct

Name: moaCB [H]

Synonym: Franean1_0691

Alternate gene names: 158312548

Gene position: 810356-810919 (Clockwise)

Preceding gene: 158312547

Following gene: 158312549

Centisome position: 9.02

GC content: 77.13

Gene sequence:

>564_bases
GTGAGTGGCGCCTCCGGGCTGCCGGCAGGGGCTCGGGCGCGGGTCGTGACGGTGTCCGACCGCGCTCACCGCGGCGCCTA
TCCCGACCGCTCGGGCCCGCTGCTGGTCGACGCCCTGGTCGGGATGGGCTTCGACGTGCCCGCGCCGGTCGTGGTCCCGG
ACGAGCGGGTGGAGATAACCGCGGCCCTGCGCGCGGCCGTCGACGCCGGGATCGACCTGGTGGTGACCACCGGGGGAACC
GGTCTCGGGCCGCGGGACGTCACACCGGAGGCCACAAGGGACCTGCTTGACCGAGAGGTGCCCGGGCTGGCCGAGGCGCT
GCGGGCGGCCGGGCGGCTCAAGGTGCCCACCGCGGTCCTCTCCCGTGGCCTCGTCGGCACCATCGGAACGACCCTGGTCG
TGAACCTGCCCGGCTCGACCGGGGGAGTGCGCGACGGCGCCGCGGTCCTCGCCCCGGTCGTCGCGCACGCGATCGCGCAG
CTGCGAGGCGGCACCGACCACTCCGGCGGCCCGTCGGGTACGGCGCCCCACCCGCCCGCGTCCACCGGGGGCACACCGGC
GTGA

Upstream 100 bases:

>100_bases
TCGTCGCCAAGACCGGCGGGAAGTCCGGGGACTGGCACCGCGACGGCGCCGGGCCGCCGGGAGACGGGGCTGGGGTGCCG
CGAGACGGGGCCGGACCGTC

Downstream 100 bases:

>100_bases
GAGCGCCTGGCTGGCCGGTCACCCTGCGCCACGATGACGTCGTCGTCCGGCCCATGCGCCTGCGTGACGCCCCGACCTGG
GTCGAGGTCCGCACGCGCAA

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: Molybdenum cofactor biosynthesis protein C; Molybdenum cofactor biosynthesis protein B [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSGASGLPAGARARVVTVSDRAHRGAYPDRSGPLLVDALVGMGFDVPAPVVVPDERVEITAALRAAVDAGIDLVVTTGGT
GLGPRDVTPEATRDLLDREVPGLAEALRAAGRLKVPTAVLSRGLVGTIGTTLVVNLPGSTGGVRDGAAVLAPVVAHAIAQ
LRGGTDHSGGPSGTAPHPPASTGGTPA

Sequences:

>Translated_187_residues
MSGASGLPAGARARVVTVSDRAHRGAYPDRSGPLLVDALVGMGFDVPAPVVVPDERVEITAALRAAVDAGIDLVVTTGGT
GLGPRDVTPEATRDLLDREVPGLAEALRAAGRLKVPTAVLSRGLVGTIGTTLVVNLPGSTGGVRDGAAVLAPVVAHAIAQ
LRGGTDHSGGPSGTAPHPPASTGGTPA
>Mature_186_residues
SGASGLPAGARARVVTVSDRAHRGAYPDRSGPLLVDALVGMGFDVPAPVVVPDERVEITAALRAAVDAGIDLVVTTGGTG
LGPRDVTPEATRDLLDREVPGLAEALRAAGRLKVPTAVLSRGLVGTIGTTLVVNLPGSTGGVRDGAAVLAPVVAHAIAQL
RGGTDHSGGPSGTAPHPPASTGGTPA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=155, Percent_Identity=41.9354838709677, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI10880983, Length=155, Percent_Identity=41.9354838709677, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1786190, Length=139, Percent_Identity=41.0071942446043, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1787000, Length=155, Percent_Identity=35.4838709677419, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564954, Length=160, Percent_Identity=41.875, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI17136978, Length=147, Percent_Identity=40.1360544217687, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24638841, Length=147, Percent_Identity=40.1360544217687, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR020817
- InterPro:   IPR012247
- InterPro:   IPR001453
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC; PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18388; Mature: 18257

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGASGLPAGARARVVTVSDRAHRGAYPDRSGPLLVDALVGMGFDVPAPVVVPDERVEIT
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEECCCCCHHHH
AALRAAVDAGIDLVVTTGGTGLGPRDVTPEATRDLLDREVPGLAEALRAAGRLKVPTAVL
HHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHH
SRGLVGTIGTTLVVNLPGSTGGVRDGAAVLAPVVAHAIAQLRGGTDHSGGPSGTAPHPPA
HCCCHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
STGGTPA
CCCCCCC
>Mature Secondary Structure 
SGASGLPAGARARVVTVSDRAHRGAYPDRSGPLLVDALVGMGFDVPAPVVVPDERVEIT
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEECCCCCHHHH
AALRAAVDAGIDLVVTTGGTGLGPRDVTPEATRDLLDREVPGLAEALRAAGRLKVPTAVL
HHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHH
SRGLVGTIGTTLVVNLPGSTGGVRDGAAVLAPVVAHAIAQLRGGTDHSGGPSGTAPHPPA
HCCCHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
STGGTPA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]