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The map label for this gene is tesB [H]

Identifier: 158312494

GI number: 158312494

Start: 741417

End: 742295

Strand: Direct

Name: tesB [H]

Synonym: Franean1_0637

Alternate gene names: 158312494

Gene position: 741417-742295 (Clockwise)

Preceding gene: 158312493

Following gene: 158312495

Centisome position: 8.25

GC content: 76.91

Gene sequence:

>879_bases
GTGGACAGGGTCGTGCGTCGCGGTGCCGCCCGGCCACCGGCTCGGGGCACCGCACCGACCTTTCGTGGCGTCGCCGAGCT
CGAGGCCGTCGACCGCGACGTCTTCCGAGGCGGCACCGGGGGCGTGCCCGTCCACCTGGGGCAGGTCGCCGTCCAGGCGC
AGCTCGCGGCCGGGCGGACGGTGGGCTCGGGGCATCCCCTGCATTCGGTGCAGGCCCAGTTCCCGCGCCCTCCGCGCGAG
GTGCACTCGGTCGTGTACCTCGTCGACCGGGTCCGGGACGGGGCCACGTCCGTGACCCGGCGGGTGACGGGGGTGCAGGC
CGGTGAGGTGGTCTGCGCGATGCACCTGTCGTACCAGCGGGGCTGGCGTGGCGGACACCAGTTGCGCGCTCCCCGCGTGC
CGCCCCCCGAGGCCCTGGAGCGCTGGCGCACCGACCCCCGGGAGCTGGGCGACCTGCTCGTCGACCTGCGGCTGGCAGCC
GGTCCAGGAACCGCTGCCGGTGGTCCAGCGGGTAGGGGCGCCCGGTCTGGTGGGAACGGGCCGGGGCGCCCGATCGCCTG
GGTGCGCCTCGTCGAGGGGCTACCGGACGACCAGCGCCTGCACGCCGGCGCGCTGACCTACATCGCCGGCCACGCCGCGG
CCGCCCTCGCCAACTGGCCGCCGCCAGCTGCCCGCGCGCCGGTCGGTGGGGAACCGTCCCGGGCGGCGGCGCTCGACCAT
GCCGCCTGGTTCCACCGCCCGTTCCGGGCCGACGAGTGGCTGCTCCTCGTCCAGGACAGCCCGTCCGGCGCGGGCCCGCG
GACGTTCACCCGGGCCACCTTCTTCGACCGGGACGGCCTGCTGGTCGCCTCGACCGCCCAGGAGCTGGCTCTCGGCTGA

Upstream 100 bases:

>100_bases
ACGCCCACCGGACGGCCCATCCACCCGCGATCACCGGGCTCCCGGGCCGAGGACACCGGGGCTGGTCCGCGAGGTTCGCC
TGACGCCGCTGCGGATAACC

Downstream 100 bases:

>100_bases
TCCCGCCCTGACCCTGGCCCCGGACCACCCGCCTCGGACCACCCGCCTCGGACCACCCGCCTCGGATCGGGGGCCCCGAA
CTTGCGGGTGCGGCCAGGAT

Product: acyl-CoA thioesterase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDRVVRRGAARPPARGTAPTFRGVAELEAVDRDVFRGGTGGVPVHLGQVAVQAQLAAGRTVGSGHPLHSVQAQFPRPPRE
VHSVVYLVDRVRDGATSVTRRVTGVQAGEVVCAMHLSYQRGWRGGHQLRAPRVPPPEALERWRTDPRELGDLLVDLRLAA
GPGTAAGGPAGRGARSGGNGPGRPIAWVRLVEGLPDDQRLHAGALTYIAGHAAAALANWPPPAARAPVGGEPSRAAALDH
AAWFHRPFRADEWLLLVQDSPSGAGPRTFTRATFFDRDGLLVASTAQELALG

Sequences:

>Translated_292_residues
MDRVVRRGAARPPARGTAPTFRGVAELEAVDRDVFRGGTGGVPVHLGQVAVQAQLAAGRTVGSGHPLHSVQAQFPRPPRE
VHSVVYLVDRVRDGATSVTRRVTGVQAGEVVCAMHLSYQRGWRGGHQLRAPRVPPPEALERWRTDPRELGDLLVDLRLAA
GPGTAAGGPAGRGARSGGNGPGRPIAWVRLVEGLPDDQRLHAGALTYIAGHAAAALANWPPPAARAPVGGEPSRAAALDH
AAWFHRPFRADEWLLLVQDSPSGAGPRTFTRATFFDRDGLLVASTAQELALG
>Mature_292_residues
MDRVVRRGAARPPARGTAPTFRGVAELEAVDRDVFRGGTGGVPVHLGQVAVQAQLAAGRTVGSGHPLHSVQAQFPRPPRE
VHSVVYLVDRVRDGATSVTRRVTGVQAGEVVCAMHLSYQRGWRGGHQLRAPRVPPPEALERWRTDPRELGDLLVDLRLAA
GPGTAAGGPAGRGARSGGNGPGRPIAWVRLVEGLPDDQRLHAGALTYIAGHAAAALANWPPPAARAPVGGEPSRAAALDH
AAWFHRPFRADEWLLLVQDSPSGAGPRTFTRATFFDRDGLLVASTAQELALG

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=295, Percent_Identity=29.8305084745763, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1786657, Length=277, Percent_Identity=33.5740072202166, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17558508, Length=304, Percent_Identity=29.6052631578947, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988741, Length=297, Percent_Identity=28.956228956229, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 30855; Mature: 30855

Theoretical pI: Translated: 11.62; Mature: 11.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVVRRGAARPPARGTAPTFRGVAELEAVDRDVFRGGTGGVPVHLGQVAVQAQLAAGRT
CCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCC
VGSGHPLHSVQAQFPRPPREVHSVVYLVDRVRDGATSVTRRVTGVQAGEVVCAMHLSYQR
CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEHHHHHH
GWRGGHQLRAPRVPPPEALERWRTDPRELGDLLVDLRLAAGPGTAAGGPAGRGARSGGNG
CCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCC
PGRPIAWVRLVEGLPDDQRLHAGALTYIAGHAAAALANWPPPAARAPVGGEPSRAAALDH
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
AAWFHRPFRADEWLLLVQDSPSGAGPRTFTRATFFDRDGLLVASTAQELALG
HHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCEEEECCHHHHHCC
>Mature Secondary Structure
MDRVVRRGAARPPARGTAPTFRGVAELEAVDRDVFRGGTGGVPVHLGQVAVQAQLAAGRT
CCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCC
VGSGHPLHSVQAQFPRPPREVHSVVYLVDRVRDGATSVTRRVTGVQAGEVVCAMHLSYQR
CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEHHHHHH
GWRGGHQLRAPRVPPPEALERWRTDPRELGDLLVDLRLAAGPGTAAGGPAGRGARSGGNG
CCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCC
PGRPIAWVRLVEGLPDDQRLHAGALTYIAGHAAAALANWPPPAARAPVGGEPSRAAALDH
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
AAWFHRPFRADEWLLLVQDSPSGAGPRTFTRATFFDRDGLLVASTAQELALG
HHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCEEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]