Click here to switch to the map view.

The map label for this gene is oxaA

Identifier: 157964068

GI number: 157964068

Start: 5171988

End: 5173625

Strand: Reverse

Name: oxaA

Synonym: Spea_4257

Alternate gene names: 157964068

Gene position: 5173625-5171988 (Counterclockwise)

Preceding gene: 157964069

Following gene: 157964067

Centisome position: 99.98

GC content: 43.28

Gene sequence:

>1638_bases
ATGGAATCTCAACGCAATATATTGCTGATCGGTTTGCTGTTTGTCAGCTTTCTACTGTGGCAACAGTGGCAAGCAGATAA
AGCGCCTCAACCGGTGGCTGCAGCTCAAACTCAATCTTCTATCCCGGCTTCTACAGTAGCTGACGCTCATAGTTCAGACG
TACCTGATGCTGATTCAGCAGTACCTGAAGCTACTCCAGCATCTAAAGAACTCATCACAGTTATTACAGACCAACTAGAA
ATCAAAATTGATCCTGTTGGCGGTGATATTGTTTACTCTGCTTTGCTTTCTCATAAGCTTGAAGAAAAAGGTGACGATCC
GTTCGTTCTTCTTGAGCAGACAAACGATATCTATTACATCGCGCAAAGTGGCCTTATTGGTCGTGACGGTATCGACAGCA
GCGTAAAAGGTCGAGCTCACTTTGATAGCGCTTCACGTGAGTACAAATTGGCTGATGGCCAAGAGACACTTAACGTGCCA
CTAACTTATGTTAGTGATAAAGGCGTGGCTTATACCAAAGTTTTCGTTTTCACTCGCGGTAAATACAACATCGCTGTTGA
TTACAAAATCAACAACACTTCTGATGCTCAGCTTCAAGTTCAAATGTATGGACAAATTAAGCACAGCATCAAGAAGAGCG
AAAGCAGCATGATGATGCCAACTTACCGTGGTGGTGCATTCTCAACAGCGGACACTCGCTATGAGAAGTACAGCTTCGAT
GATATGGCAGATAAGAACCTAGACAAGTCAACACTTGGCGGTTGGGTTGCTATGCTTCAGCATTACTTTGTATCAGCATG
GGTACCACCTGCGAACGATAAGAACATTATCTTCTCAAGTGTCAGTGCTGGTGGTCTAGCTAACATAGGTTTCCGTGGTG
CACTTTACGATATCGCACCTGGTACTGAACAAAGCATTAAAGCTGAATTCTATGTTGGTCCTAAAGATCAAGAAGCCCTA
TCGGCACTTTCTCCATCACTGAATCTAGTAGTAGATTATGGTTTCCTTTGGTGGTTAGCAGTACCTATCTACAAACTATT
GATGTTCTTCCAATCAATCGTTGGTAACTGGGGTATCGCTATTATCCTAATCACTCTAACTGTTCGTGGTATGTTATATC
CGCTAACGAAAGCGCAATACACCTCTATGGCGAAAATGCGTAATCTGCAGCCTAAGCTTGCCGAACTAAAAGAGCGCTTT
GGTGATGACCGTCAGAAGATGGGTCAAGCTATGATGGAACTGTACAAGAAAGAGAAAGTGAACCCTATGGGTGGCTGTCT
TCCAATCTTGCTACAGATGCCAATCTTCATCGCTCTATACTGGGTTCTATTAGAAAGTGTTGAACTGCGTCATGCGCCAT
TCATGCTTTGGATTACTGACTTATCAGTACAAGATCCTTACTATGTTATGCCTATCCTAATGGGTATCTCGATGTTTGTG
ATGCAGAAGATGCAGCCAATGGCACCGACTATGGATCCAATGCAAGTTAAAATGATGCAGTGGATGCCTGTAATCTTTAC
CGTATTCTTCCTATGGTTCCCAGCAGGTCTGGTTCTATACTGGTTGGTAGGTAACTTAGTCGCGATTACCCAGCAGAAAA
TTATCTATGCGGGTCTAGAGAAAAAAGGGTTAAAATAA

Upstream 100 bases:

>100_bases
GTGTTGGTTTGCAGGTAAACGCATATTAAGATGTCACCCTTTACATCCGGGCGGTGAAGACCCCGTCCCTAACAAAAAAC
ATAGGTGCGATAAATAGGTT

Downstream 100 bases:

>100_bases
CCTTTAGCTCAGACTAATAAAAAGCGGTCAATACTGAGTATTGACCGCTTTTTTGCTTTCTATGTAGAGACAATATTTTT
AACTTCACCCGAAAAATCAA

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MESQRNILLIGLLFVSFLLWQQWQADKAPQPVAAAQTQSSIPASTVADAHSSDVPDADSAVPEATPASKELITVITDQLE
IKIDPVGGDIVYSALLSHKLEEKGDDPFVLLEQTNDIYYIAQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQETLNVP
LTYVSDKGVAYTKVFVFTRGKYNIAVDYKINNTSDAQLQVQMYGQIKHSIKKSESSMMMPTYRGGAFSTADTRYEKYSFD
DMADKNLDKSTLGGWVAMLQHYFVSAWVPPANDKNIIFSSVSAGGLANIGFRGALYDIAPGTEQSIKAEFYVGPKDQEAL
SALSPSLNLVVDYGFLWWLAVPIYKLLMFFQSIVGNWGIAIILITLTVRGMLYPLTKAQYTSMAKMRNLQPKLAELKERF
GDDRQKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVMPILMGISMFV
MQKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLEKKGLK

Sequences:

>Translated_545_residues
MESQRNILLIGLLFVSFLLWQQWQADKAPQPVAAAQTQSSIPASTVADAHSSDVPDADSAVPEATPASKELITVITDQLE
IKIDPVGGDIVYSALLSHKLEEKGDDPFVLLEQTNDIYYIAQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQETLNVP
LTYVSDKGVAYTKVFVFTRGKYNIAVDYKINNTSDAQLQVQMYGQIKHSIKKSESSMMMPTYRGGAFSTADTRYEKYSFD
DMADKNLDKSTLGGWVAMLQHYFVSAWVPPANDKNIIFSSVSAGGLANIGFRGALYDIAPGTEQSIKAEFYVGPKDQEAL
SALSPSLNLVVDYGFLWWLAVPIYKLLMFFQSIVGNWGIAIILITLTVRGMLYPLTKAQYTSMAKMRNLQPKLAELKERF
GDDRQKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVMPILMGISMFV
MQKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLEKKGLK
>Mature_545_residues
MESQRNILLIGLLFVSFLLWQQWQADKAPQPVAAAQTQSSIPASTVADAHSSDVPDADSAVPEATPASKELITVITDQLE
IKIDPVGGDIVYSALLSHKLEEKGDDPFVLLEQTNDIYYIAQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQETLNVP
LTYVSDKGVAYTKVFVFTRGKYNIAVDYKINNTSDAQLQVQMYGQIKHSIKKSESSMMMPTYRGGAFSTADTRYEKYSFD
DMADKNLDKSTLGGWVAMLQHYFVSAWVPPANDKNIIFSSVSAGGLANIGFRGALYDIAPGTEQSIKAEFYVGPKDQEAL
SALSPSLNLVVDYGFLWWLAVPIYKLLMFFQSIVGNWGIAIILITLTVRGMLYPLTKAQYTSMAKMRNLQPKLAELKERF
GDDRQKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVMPILMGISMFV
MQKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLEKKGLK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=552, Percent_Identity=50.1811594202899, Blast_Score=544, Evalue=1e-156,
Organism=Drosophila melanogaster, GI24662345, Length=195, Percent_Identity=25.1282051282051, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356443, Length=195, Percent_Identity=25.1282051282051, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_SHEPA (A8HAI0)

Other databases:

- EMBL:   CP000851
- RefSeq:   YP_001504102.1
- ProteinModelPortal:   A8HAI0
- SMR:   A8HAI0
- STRING:   A8HAI0
- GeneID:   5664641
- GenomeReviews:   CP000851_GR
- KEGG:   spl:Spea_4257
- NMPDR:   fig|398579.3.peg.3697
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- ProtClustDB:   CLSK905534
- BioCyc:   SPEA398579:SPEA_4257-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 61049; Mature: 61049

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f761e1c)-; HASH(0x1f1c8748)-; HASH(0x1f77949c)-; HASH(0x1f12ca8c)-; HASH(0x1f9420f4)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQRNILLIGLLFVSFLLWQQWQADKAPQPVAAAQTQSSIPASTVADAHSSDVPDADSA
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHCCCCCCCCCCCCC
VPEATPASKELITVITDQLEIKIDPVGGDIVYSALLSHKLEEKGDDPFVLLEQTNDIYYI
CCCCCCCCHHHHHEEECCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEE
AQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQETLNVPLTYVSDKGVAYTKVFVFTRG
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEECCCEEEECCCCCEEEEEEEEECC
KYNIAVDYKINNTSDAQLQVQMYGQIKHSIKKSESSMMMPTYRGGAFSTADTRYEKYSFD
CEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCCEECEEECCCCCCCCCCCHHHCCCH
DMADKNLDKSTLGGWVAMLQHYFVSAWVPPANDKNIIFSSVSAGGLANIGFRGALYDIAP
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCC
GTEQSIKAEFYVGPKDQEALSALSPSLNLVVDYGFLWWLAVPIYKLLMFFQSIVGNWGIA
CCCCCEEEEEEECCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IILITLTVRGMLYPLTKAQYTSMAKMRNLQPKLAELKERFGDDRQKMGQAMMELYKKEKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
NPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVMPILMGISMFV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
MQKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLE
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCH
KKGLK
HCCCH
>Mature Secondary Structure
MESQRNILLIGLLFVSFLLWQQWQADKAPQPVAAAQTQSSIPASTVADAHSSDVPDADSA
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHCCCCCCCCCCCCC
VPEATPASKELITVITDQLEIKIDPVGGDIVYSALLSHKLEEKGDDPFVLLEQTNDIYYI
CCCCCCCCHHHHHEEECCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEE
AQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQETLNVPLTYVSDKGVAYTKVFVFTRG
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEECCCEEEECCCCCEEEEEEEEECC
KYNIAVDYKINNTSDAQLQVQMYGQIKHSIKKSESSMMMPTYRGGAFSTADTRYEKYSFD
CEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCCEECEEECCCCCCCCCCCHHHCCCH
DMADKNLDKSTLGGWVAMLQHYFVSAWVPPANDKNIIFSSVSAGGLANIGFRGALYDIAP
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCC
GTEQSIKAEFYVGPKDQEALSALSPSLNLVVDYGFLWWLAVPIYKLLMFFQSIVGNWGIA
CCCCCEEEEEEECCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IILITLTVRGMLYPLTKAQYTSMAKMRNLQPKLAELKERFGDDRQKMGQAMMELYKKEKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
NPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVMPILMGISMFV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
MQKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLE
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCH
KKGLK
HCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA