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The map label for this gene is atpA2 [H]

Identifier: 157964053

GI number: 157964053

Start: 5156243

End: 5157784

Strand: Reverse

Name: atpA2 [H]

Synonym: Spea_4242

Alternate gene names: 157964053

Gene position: 5157784-5156243 (Counterclockwise)

Preceding gene: 157964054

Following gene: 157964052

Centisome position: 99.68

GC content: 46.37

Gene sequence:

>1542_bases
ATGCAACTGAATTCCACTGAAATCAGCGATCTGATTAAACAGCGGATCGAGCAGTTCGAAGTCGTTAGTGAAGCTCGCAA
CGAAGGTACTATCGTTGCAGTAAGTGACGGCATCATCCGCATCCACGGCCTAGCCGATGTAATGCAGGGTGAAATGATCG
AGCTGCCTGGCAACCGTTTTGCAATCGCGTTGAACTTAGAACGTGATTCTGTCGGTGCCGTAGTAATGGGCCCTTATGCC
ACTTTGGCAGAAGGCGACAAAGTTAAAACAACAGGCCGTATTTTGGAAGTACCTGTTGGCCGTGGTCTATTAGGCCGTGT
AGTCAACACTCTAGGTGAACCAATTGACGGTAAAGGACCTATCGATAGCGATGGTTTCTCTCCTGTTGAAGTAATTGCAC
CTGGTGTAATTGAGCGTAAATCAGTCGATCAGCCAGTGCAAACTGGTTATAAAGCCGTTGACTCTATGATCCCAATCGGT
CGTGGACAACGTGAATTGATCATTGGTGACCGCCAGATCGGTAAAACCGCTCTAGCGATCGACGCGATTATCAACCAAAA
AGATTCTGGCATTAAGTGTGTATACGTTGCAGTAGGCCAAAAGGCTTCTACTATCGCTAACGTGGTACGCAAGCTAGAAG
AGCACGGCGCTTTGGCGAACACCATTGTTGTTGTTGCTACAGCTTCTGAAGCTGCTGCACTACAATATTTGGCTCCATAC
TCTGGTTGTACAATGGGTGAATACTTCCGCGACCGCGGTGAAGACTCACTAATCGTATATGATGATTTGTCTAAGCAAGC
AGTTGCTTACCGTCAGATCTCATTGCTTCTTAAGCGTCCACCAGGACGTGAAGCATACCCAGGTGATGTATTCTATCTTC
ACTCTCGTCTGTTGGAACGTGCTTCACGTGTTAACGCCGAGTATGTTGAGAAGTTCACTAAAGGTGAAGTTAAAGGCCAA
ACTGGTTCTTTGACTGCTCTACCAATTATTGAAACTCAAGCTGGTGACGTTTCTGCATTCGTACCGACTAACGTAATTTC
GATTACCGATGGTCAGATCTTCCTTGAAACAGACCTGTTTAACTCTGGCTTACGTCCAGCTGTTAACCCTGGTATCTCTG
TTTCTCGTGTTGGTGGTGCGGCGCAGACTAAGATCATCAAGAAACTGTCTGGTGGTATCCGTACCGCTCTTGCACAGTAT
CGAGAGCTTGCAGCGTTCTCACAGTTTGCATCTGACTTAGATGATGCAACTCGTGCTCAGCTTGAGCATGGTGAGCGTGT
TACCGAACTAATGAAGCAAAAGCAATATGCTCCAATGAGTATCGCTGATCAGTCTGTGTCTATTTTCGCAGCTGAAAAAG
GTTACTTGAAGAGTGTTGCGCTGAATAAAGTCGGTGATTTCGAAGCGTCTCTGCTCTCTTTCATGAACAGTGAACATGCT
GACCTAATGAAGACTATCAACGATACTGGCGATTATAACGCTGATATCGAAGGTGAGTTGAAGGCTAGCCTGGACAAGTT
CGTAGAAACCCAAACCTGGTAA

Upstream 100 bases:

>100_bases
GTGTAATTATCACGGCAGGAGACTTAGTCATTGATGGCTCGGTCCGCGGAAAAATTTCGCGTCTGTCTGATTCGCTGCAA
TCGTAATTGGGAGTTTGAGC

Downstream 100 bases:

>100_bases
ATTTTAGAGGTGCCTCTGGCACCTCAGGTCCAGAATTGGAGAGTAAAGATGGCCAACGCTAAAGAGATTAAAACCAAGAT
CGCGAGTGTTCAAAACACTC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2 [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISDLIKQRIEQFEVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYA
TLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPIDSDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQIGKTALAIDAIINQKDSGIKCVYVAVGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
SGCTMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAEYVEKFTKGEVKGQ
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQY
RELAAFSQFASDLDDATRAQLEHGERVTELMKQKQYAPMSIADQSVSIFAAEKGYLKSVALNKVGDFEASLLSFMNSEHA
DLMKTINDTGDYNADIEGELKASLDKFVETQTW

Sequences:

>Translated_513_residues
MQLNSTEISDLIKQRIEQFEVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYA
TLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPIDSDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQIGKTALAIDAIINQKDSGIKCVYVAVGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
SGCTMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAEYVEKFTKGEVKGQ
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQY
RELAAFSQFASDLDDATRAQLEHGERVTELMKQKQYAPMSIADQSVSIFAAEKGYLKSVALNKVGDFEASLLSFMNSEHA
DLMKTINDTGDYNADIEGELKASLDKFVETQTW
>Mature_513_residues
MQLNSTEISDLIKQRIEQFEVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYA
TLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPIDSDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQIGKTALAIDAIINQKDSGIKCVYVAVGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
SGCTMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAEYVEKFTKGEVKGQ
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQY
RELAAFSQFASDLDDATRAQLEHGERVTELMKQKQYAPMSIADQSVSIFAAEKGYLKSVALNKVGDFEASLLSFMNSEHA
DLMKTINDTGDYNADIEGELKASLDKFVETQTW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=512, Percent_Identity=55.46875, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI4757810, Length=512, Percent_Identity=55.46875, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI32189394, Length=362, Percent_Identity=27.0718232044199, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19913428, Length=316, Percent_Identity=27.8481012658228, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI19913426, Length=313, Percent_Identity=27.1565495207668, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI19913424, Length=267, Percent_Identity=28.0898876404494, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=85.3801169590643, Blast_Score=912, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=340, Percent_Identity=27.0588235294118, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788251, Length=386, Percent_Identity=24.0932642487047, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=55.9223300970874, Blast_Score=560, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=55.9223300970874, Blast_Score=558, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=52.0388349514563, Blast_Score=508, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=25.8152173913043, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=310, Percent_Identity=26.1290322580645, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=370, Percent_Identity=26.2162162162162, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17565854, Length=262, Percent_Identity=27.0992366412214, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=65.9574468085106, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=54.1910331384016, Blast_Score=567, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6322581, Length=367, Percent_Identity=28.0653950953678, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319603, Length=376, Percent_Identity=27.6595744680851, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=54.4747081712062, Blast_Score=549, Evalue=1e-156,
Organism=Drosophila melanogaster, GI281361666, Length=354, Percent_Identity=27.4011299435028, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24646341, Length=354, Percent_Identity=27.4011299435028, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17136796, Length=354, Percent_Identity=27.4011299435028, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24638766, Length=324, Percent_Identity=27.4691358024691, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=26.4797507788162, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24583988, Length=267, Percent_Identity=28.4644194756554, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24583986, Length=267, Percent_Identity=28.4644194756554, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24583984, Length=267, Percent_Identity=28.4644194756554, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24583992, Length=359, Percent_Identity=25.6267409470752, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129479, Length=376, Percent_Identity=25.2659574468085, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55388; Mature: 55388

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISDLIKQRIEQFEVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYATLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCCHHHCCCCCEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IDSDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQIGKTALAI
CCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCHHHHHH
DAIINQKDSGIKCVYVAVGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHCCC
SGCTMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNAEYVEKFTKGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFSQFASDLDDATRAQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHGERVTELMKQKQYAPMSIADQSVSIFAAEKGYLKSVALNKVGDFEASLLSFMNSEHA
HHCCHHHHHHHHHHCCCCCEECCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHCCCHH
DLMKTINDTGDYNADIEGELKASLDKFVETQTW
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNSTEISDLIKQRIEQFEVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYATLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCCHHHCCCCCEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IDSDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQIGKTALAI
CCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCHHHHHH
DAIINQKDSGIKCVYVAVGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHCCC
SGCTMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNAEYVEKFTKGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFSQFASDLDDATRAQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHGERVTELMKQKQYAPMSIADQSVSIFAAEKGYLKSVALNKVGDFEASLLSFMNSEHA
HHCCHHHHHHHHHHCCCCCEECCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHCCCHH
DLMKTINDTGDYNADIEGELKASLDKFVETQTW
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA