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The map label for this gene is gpsA [H]

Identifier: 157964025

GI number: 157964025

Start: 5121506

End: 5122525

Strand: Reverse

Name: gpsA [H]

Synonym: Spea_4214

Alternate gene names: 157964025

Gene position: 5122525-5121506 (Counterclockwise)

Preceding gene: 157964026

Following gene: 157964023

Centisome position: 98.99

GC content: 49.31

Gene sequence:

>1020_bases
ATGAAAAACACTGCCGACATTACGGTACTGGGGGCGGGCTCTTACGGGACCGCCCTTGCCATTTCTTTAGCGAGCAATGG
CCACAGAACCATGCTTTGGGGCCACGAACCCGAGCACATAGAAAACCTGAAAAACGACAAGTCCAACGAAGCGTTTTTGC
CAGGTATTCCATTACCAGACTTACTGATCCCAGAAGCGGACTTAGCAACAGCATTAGCGGCATCTAACAATGTGCTAGTG
GTTGTACCTAGTCATGTTTTTGGATTAGTGCTGACTCAAGCAAAACCGCTGTTACGCAAAGATTCGCGTATTGTGTGGGC
CACTAAAGGTCTAGAGCCTGAAACTGGCCGCTTAATACAAGATGTTGCCCGTGAAGCCATTGGCGATGAGTTTCCTCTTG
CCGTGTTATCGGGCCCGACTTTTGCCAAAGAGTTAGCTGCCGGTATGCCAACTGCGATTTCGATTGCAGGTACCGATCCT
CAGTTTACTAAGGATTTGGTCGAGCTGTTACACAGCCCTAAGCGTCTGCGTGTATACGCCAATGACGACTTTATTGGTCT
ACAGCTTGGCGGCGCAGTTAAAAACGTTATCGCGATTGGCGCAGGCTTATCAGACGGTATCGGTTTTGGTGCGAATGCAA
GAACAGCACTAATTACTCGCGGCTTAGTTGAGTTGACCCGTCTTGGTGAAGCTATGGGTGCGCAAGCCTCAACCTTTATG
GGGATGGCTGGCTTGGGTGACTTGGTACTGACTTGTACCGACAATCAGTCACGTAACCGTCGCTTTGGTTTAGCATTGGG
CAAAGGCTCAGATGTTGAAACCGCACAAGACGAAATTGGTCAAGTGGTTGAAGGTTATCGCAACACTAAAGAGGTCTACA
CGCTAGCTAAGCGTTTAGGCGTCGAGATGCCTATCACCGAACAGGTTTACCAAGTCTTGTATAAGGGCAAGTCTCCAGTT
GATGCAGCTAAAGAGCTACTCAGCCGTGAGAAGAAGTCTGAGACATCGTCGGCAGAATAG

Upstream 100 bases:

>100_bases
CTAGCGCCAGTTAACTTTGACGCACTATTTGCTCAGTATGTTCAACAGCGTCAAGCTGCTGCAGCTGAAGCACCAGCAGA
AGAAGCTAACGCTTAATCGC

Downstream 100 bases:

>100_bases
TTTTACTGCTAATAGACTGAATAATTCATTTAGTAGATTAAAAACCGAAGCCTAGCTTCGGTTTTTTTGTTTTCACGACC
GTAATACCGGTCAGTTATTC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKNTADITVLGAGSYGTALAISLASNGHRTMLWGHEPEHIENLKNDKSNEAFLPGIPLPDLLIPEADLATALAASNNVLV
VVPSHVFGLVLTQAKPLLRKDSRIVWATKGLEPETGRLIQDVAREAIGDEFPLAVLSGPTFAKELAAGMPTAISIAGTDP
QFTKDLVELLHSPKRLRVYANDDFIGLQLGGAVKNVIAIGAGLSDGIGFGANARTALITRGLVELTRLGEAMGAQASTFM
GMAGLGDLVLTCTDNQSRNRRFGLALGKGSDVETAQDEIGQVVEGYRNTKEVYTLAKRLGVEMPITEQVYQVLYKGKSPV
DAAKELLSREKKSETSSAE

Sequences:

>Translated_339_residues
MKNTADITVLGAGSYGTALAISLASNGHRTMLWGHEPEHIENLKNDKSNEAFLPGIPLPDLLIPEADLATALAASNNVLV
VVPSHVFGLVLTQAKPLLRKDSRIVWATKGLEPETGRLIQDVAREAIGDEFPLAVLSGPTFAKELAAGMPTAISIAGTDP
QFTKDLVELLHSPKRLRVYANDDFIGLQLGGAVKNVIAIGAGLSDGIGFGANARTALITRGLVELTRLGEAMGAQASTFM
GMAGLGDLVLTCTDNQSRNRRFGLALGKGSDVETAQDEIGQVVEGYRNTKEVYTLAKRLGVEMPITEQVYQVLYKGKSPV
DAAKELLSREKKSETSSAE
>Mature_339_residues
MKNTADITVLGAGSYGTALAISLASNGHRTMLWGHEPEHIENLKNDKSNEAFLPGIPLPDLLIPEADLATALAASNNVLV
VVPSHVFGLVLTQAKPLLRKDSRIVWATKGLEPETGRLIQDVAREAIGDEFPLAVLSGPTFAKELAAGMPTAISIAGTDP
QFTKDLVELLHSPKRLRVYANDDFIGLQLGGAVKNVIAIGAGLSDGIGFGANARTALITRGLVELTRLGEAMGAQASTFM
GMAGLGDLVLTCTDNQSRNRRFGLALGKGSDVETAQDEIGQVVEGYRNTKEVYTLAKRLGVEMPITEQVYQVLYKGKSPV
DAAKELLSREKKSETSSAE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=336, Percent_Identity=28.2738095238095, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI24307999, Length=344, Percent_Identity=28.1976744186047, Blast_Score=130, Evalue=1e-30,
Organism=Escherichia coli, GI1790037, Length=336, Percent_Identity=72.6190476190476, Blast_Score=507, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI32564399, Length=338, Percent_Identity=26.6272189349112, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193210136, Length=339, Percent_Identity=26.5486725663717, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32564403, Length=339, Percent_Identity=26.5486725663717, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17507425, Length=336, Percent_Identity=24.4047619047619, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193210134, Length=212, Percent_Identity=28.7735849056604, Blast_Score=81, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6320181, Length=340, Percent_Identity=27.9411764705882, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6324513, Length=342, Percent_Identity=26.0233918128655, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17136200, Length=358, Percent_Identity=26.2569832402235, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136202, Length=343, Percent_Identity=26.8221574344023, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136204, Length=343, Percent_Identity=26.8221574344023, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI22026922, Length=349, Percent_Identity=22.9226361031519, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281362270, Length=263, Percent_Identity=28.8973384030418, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45551945, Length=263, Percent_Identity=28.8973384030418, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24648969, Length=209, Percent_Identity=31.1004784688995, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36032; Mature: 36032

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTADITVLGAGSYGTALAISLASNGHRTMLWGHEPEHIENLKNDKSNEAFLPGIPLPD
CCCCCEEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCEEECCCCCCC
LLIPEADLATALAASNNVLVVVPSHVFGLVLTQAKPLLRKDSRIVWATKGLEPETGRLIQ
CCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHCCHHHHCCCEEEEEECCCCCCHHHHHH
DVAREAIGDEFPLAVLSGPTFAKELAAGMPTAISIAGTDPQFTKDLVELLHSPKRLRVYA
HHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEE
NDDFIGLQLGGAVKNVIAIGAGLSDGIGFGANARTALITRGLVELTRLGEAMGAQASTFM
CCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
GMAGLGDLVLTCTDNQSRNRRFGLALGKGSDVETAQDEIGQVVEGYRNTKEVYTLAKRLG
HHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
VEMPITEQVYQVLYKGKSPVDAAKELLSREKKSETSSAE
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNTADITVLGAGSYGTALAISLASNGHRTMLWGHEPEHIENLKNDKSNEAFLPGIPLPD
CCCCCEEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCEEECCCCCCC
LLIPEADLATALAASNNVLVVVPSHVFGLVLTQAKPLLRKDSRIVWATKGLEPETGRLIQ
CCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHCCHHHHCCCEEEEEECCCCCCHHHHHH
DVAREAIGDEFPLAVLSGPTFAKELAAGMPTAISIAGTDPQFTKDLVELLHSPKRLRVYA
HHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEE
NDDFIGLQLGGAVKNVIAIGAGLSDGIGFGANARTALITRGLVELTRLGEAMGAQASTFM
CCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
GMAGLGDLVLTCTDNQSRNRRFGLALGKGSDVETAQDEIGQVVEGYRNTKEVYTLAKRLG
HHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
VEMPITEQVYQVLYKGKSPVDAAKELLSREKKSETSSAE
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA