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The map label for this gene is hlyB [H]

Identifier: 157964007

GI number: 157964007

Start: 5090334

End: 5091992

Strand: Reverse

Name: hlyB [H]

Synonym: Spea_4196

Alternate gene names: 157964007

Gene position: 5091992-5090334 (Counterclockwise)

Preceding gene: 157964008

Following gene: 157964005

Centisome position: 98.4

GC content: 44.36

Gene sequence:

>1659_bases
ATGGATTGGCTAGCTTCATTTAGTATTAAACGAAAATTGATGGCGGTAATGTTGGTATTTGGCTTCGCCGGATGTGCGAT
TTTAGTTGATGTGGTGAATAGCACTGCCGCAGTTGAGCAGCGTTTTAATGAATATGACCAAGCTGCCGTAAGTAGTCAAA
AATATCTGTTATCTATCAACCGCGATATGAATTACGTGTCACGCTTATCTCGTAGCATCATGCTAGGCGATGATTTCAGC
AAAAACTACAAGCTACTCGAAACCCGGATCCAAGATATCTATAACCATTTTGAAGGATTAGATACAGCAATTAGTGCTAT
TGATAATGATGAATCACGAAGTGAGATTCGTCAGTTAGCCGATTTATCTCAACAAGCGACAGAGGCATTTTTAGAAGATG
GTCGTAATCGTATGTTAGCTCTTAAATCTGTTGAACGTTCTCCAGAGGTATTGCAACAGGCTTGGGCTGAGTATCGTGTA
GGCGCTAGCCCGTTTGCTAATGAGGCTAGACGTACTTTCAGAGATTTAACTGAAGCTGAAGAGGTTTTACGAGTCTATAT
TCAGGCCGAAGCTGCTGGTGCGTTATCTAGCATGCGCTTACAGCTATGTGCTATTACACTTGGCTCGTTTGCATTGGCCG
GATTGATTTTGTTGTTTGTTTCACGAACCATCTTACGTACCGTCGATAGTATGCGTTTATCTATCACTTCCATTGAAGCC
GATTCAGATCTTACTCGCAGAATCCACATAACCTCTCAAGACGAACTGGGTCAGTTATCAAGGTCATTTAATTTGATGTT
AGATAAATTCCAAACCAGTTTACAAAGTGTCGCCGAAACTTCGGCGTCACTAGCCGAATCATCTCAAGGTATGGCAGCAA
TTACCGCCGATTCAGCTAGTTCTGTGCAAACACAGCGTGATGAACTAGAAATGGTCGCGACGGCGATGAATGAGATGACT
GCTACCGTGGTTGAGGTTGCCAAAAATGCTAATGATGCCGCTGATGCTGCTGTGCAAACGGATACCCAGTCTCAAGCTGG
TTTAACCGTGGTGAATAATACAGTGCAAACCATTGAAGGCTTAGCCGTTGGCATTGAAAGAGCATCACAGGTAGTTAAAG
ATCTTGAGGATGACAGCCATCAAATTGGTTCAATTTTGGATGTTATCAAGGGGATTGCTGAGCAAACTAACTTATTGGCA
TTGAATGCTGCAATTGAGGCTGCACGTGCTGGCGAGCAAGGTCGAGGCTTTGCTGTGGTGGCCGACGAAGTTAGAACGCT
GGCGAGTCGCACCCAAGAGTCGACAGAAGAAATTCAAAGAATGATTGAAAAGTTACAAGGTGGCGCAAAACTCGCTGCCG
ACGCCATGTCAGATAGCCGCCAATATGTGGATGACAGCGTTAATCACGCCCGTAGTGCAGGCGAAGTTTTACAAAGTATT
GCCAAAGCCATTGCGACGATTACCGATATGAACACTCAAATTGCCACCGCAGCTGAGGAGCAAAGCACGGTATCTGAAGA
GATTAATACCAACATCGTCAATATTAGTAATGCAGCGGAAGAAACTGCAGCAGGCACAATGAGCAGCTCTCAAGAAAGCG
AAAACTTAGCCCAAATGGCCAAGCGCCTGTCGGGATTGGTACAAGAGTTTAAGATTTAA

Upstream 100 bases:

>100_bases
TATAAAATTCATGTGTTTATATCTCAATAACTATAAATGACTTGTTCTATTCTGAATGAAAATTGCGCTTACGCATTGGA
AGAATATTCGGAGTGGTAAA

Downstream 100 bases:

>100_bases
TATGAGATAAGGCTAAAGGCTAGCACTAGAGAGCGTGCTAGCTTTAATCTCAGTATTGTCTATTCACCTTTACGAGCAAT
TAAATAAGCACAGTATCCGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MDWLASFSIKRKLMAVMLVFGFAGCAILVDVVNSTAAVEQRFNEYDQAAVSSQKYLLSINRDMNYVSRLSRSIMLGDDFS
KNYKLLETRIQDIYNHFEGLDTAISAIDNDESRSEIRQLADLSQQATEAFLEDGRNRMLALKSVERSPEVLQQAWAEYRV
GASPFANEARRTFRDLTEAEEVLRVYIQAEAAGALSSMRLQLCAITLGSFALAGLILLFVSRTILRTVDSMRLSITSIEA
DSDLTRRIHITSQDELGQLSRSFNLMLDKFQTSLQSVAETSASLAESSQGMAAITADSASSVQTQRDELEMVATAMNEMT
ATVVEVAKNANDAADAAVQTDTQSQAGLTVVNNTVQTIEGLAVGIERASQVVKDLEDDSHQIGSILDVIKGIAEQTNLLA
LNAAIEAARAGEQGRGFAVVADEVRTLASRTQESTEEIQRMIEKLQGGAKLAADAMSDSRQYVDDSVNHARSAGEVLQSI
AKAIATITDMNTQIATAAEEQSTVSEEINTNIVNISNAAEETAAGTMSSSQESENLAQMAKRLSGLVQEFKI

Sequences:

>Translated_552_residues
MDWLASFSIKRKLMAVMLVFGFAGCAILVDVVNSTAAVEQRFNEYDQAAVSSQKYLLSINRDMNYVSRLSRSIMLGDDFS
KNYKLLETRIQDIYNHFEGLDTAISAIDNDESRSEIRQLADLSQQATEAFLEDGRNRMLALKSVERSPEVLQQAWAEYRV
GASPFANEARRTFRDLTEAEEVLRVYIQAEAAGALSSMRLQLCAITLGSFALAGLILLFVSRTILRTVDSMRLSITSIEA
DSDLTRRIHITSQDELGQLSRSFNLMLDKFQTSLQSVAETSASLAESSQGMAAITADSASSVQTQRDELEMVATAMNEMT
ATVVEVAKNANDAADAAVQTDTQSQAGLTVVNNTVQTIEGLAVGIERASQVVKDLEDDSHQIGSILDVIKGIAEQTNLLA
LNAAIEAARAGEQGRGFAVVADEVRTLASRTQESTEEIQRMIEKLQGGAKLAADAMSDSRQYVDDSVNHARSAGEVLQSI
AKAIATITDMNTQIATAAEEQSTVSEEINTNIVNISNAAEETAAGTMSSSQESENLAQMAKRLSGLVQEFKI
>Mature_552_residues
MDWLASFSIKRKLMAVMLVFGFAGCAILVDVVNSTAAVEQRFNEYDQAAVSSQKYLLSINRDMNYVSRLSRSIMLGDDFS
KNYKLLETRIQDIYNHFEGLDTAISAIDNDESRSEIRQLADLSQQATEAFLEDGRNRMLALKSVERSPEVLQQAWAEYRV
GASPFANEARRTFRDLTEAEEVLRVYIQAEAAGALSSMRLQLCAITLGSFALAGLILLFVSRTILRTVDSMRLSITSIEA
DSDLTRRIHITSQDELGQLSRSFNLMLDKFQTSLQSVAETSASLAESSQGMAAITADSASSVQTQRDELEMVATAMNEMT
ATVVEVAKNANDAADAAVQTDTQSQAGLTVVNNTVQTIEGLAVGIERASQVVKDLEDDSHQIGSILDVIKGIAEQTNLLA
LNAAIEAARAGEQGRGFAVVADEVRTLASRTQESTEEIQRMIEKLQGGAKLAADAMSDSRQYVDDSVNHARSAGEVLQSI
AKAIATITDMNTQIATAAEEQSTVSEEINTNIVNISNAAEETAAGTMSSSQESENLAQMAKRLSGLVQEFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=277, Percent_Identity=36.8231046931408, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788195, Length=263, Percent_Identity=37.6425855513308, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787690, Length=465, Percent_Identity=28.6021505376344, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788194, Length=374, Percent_Identity=31.8181818181818, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1789453, Length=317, Percent_Identity=31.2302839116719, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59966; Mature: 59966

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWLASFSIKRKLMAVMLVFGFAGCAILVDVVNSTAAVEQRFNEYDQAAVSSQKYLLSIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEC
RDMNYVSRLSRSIMLGDDFSKNYKLLETRIQDIYNHFEGLDTAISAIDNDESRSEIRQLA
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DLSQQATEAFLEDGRNRMLALKSVERSPEVLQQAWAEYRVGASPFANEARRTFRDLTEAE
HHHHHHHHHHHHCCCHHEEHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EVLRVYIQAEAAGALSSMRLQLCAITLGSFALAGLILLFVSRTILRTVDSMRLSITSIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
DSDLTRRIHITSQDELGQLSRSFNLMLDKFQTSLQSVAETSASLAESSQGMAAITADSAS
CCCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
SVQTQRDELEMVATAMNEMTATVVEVAKNANDAADAAVQTDTQSQAGLTVVNNTVQTIEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LAVGIERASQVVKDLEDDSHQIGSILDVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
ADEVRTLASRTQESTEEIQRMIEKLQGGAKLAADAMSDSRQYVDDSVNHARSAGEVLQSI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKAIATITDMNTQIATAAEEQSTVSEEINTNIVNISNAAEETAAGTMSSSQESENLAQMA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHCCCCCCHHHHHHHHHH
KRLSGLVQEFKI
HHHHHHHHHHCC
>Mature Secondary Structure
MDWLASFSIKRKLMAVMLVFGFAGCAILVDVVNSTAAVEQRFNEYDQAAVSSQKYLLSIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEC
RDMNYVSRLSRSIMLGDDFSKNYKLLETRIQDIYNHFEGLDTAISAIDNDESRSEIRQLA
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DLSQQATEAFLEDGRNRMLALKSVERSPEVLQQAWAEYRVGASPFANEARRTFRDLTEAE
HHHHHHHHHHHHCCCHHEEHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EVLRVYIQAEAAGALSSMRLQLCAITLGSFALAGLILLFVSRTILRTVDSMRLSITSIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
DSDLTRRIHITSQDELGQLSRSFNLMLDKFQTSLQSVAETSASLAESSQGMAAITADSAS
CCCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
SVQTQRDELEMVATAMNEMTATVVEVAKNANDAADAAVQTDTQSQAGLTVVNNTVQTIEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LAVGIERASQVVKDLEDDSHQIGSILDVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
ADEVRTLASRTQESTEEIQRMIEKLQGGAKLAADAMSDSRQYVDDSVNHARSAGEVLQSI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKAIATITDMNTQIATAAEEQSTVSEEINTNIVNISNAAEETAAGTMSSSQESENLAQMA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHCCCCCCHHHHHHHHHH
KRLSGLVQEFKI
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]