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The map label for this gene is ftsY [H]

Identifier: 157963791

GI number: 157963791

Start: 4835734

End: 4837665

Strand: Reverse

Name: ftsY [H]

Synonym: Spea_3980

Alternate gene names: 157963791

Gene position: 4837665-4835734 (Counterclockwise)

Preceding gene: 157963794

Following gene: 157963790

Centisome position: 93.49

GC content: 49.48

Gene sequence:

>1932_bases
ATGGCAAAGAAAGGTTTTTTTTCCTGGTTCCGCAAGGATAAATCTAAAGAAGAAGCGCAGGCTGCTGAAGCGGCGAAACT
AGAAGCTGAAAAGCTTGAACTTGAAAGAATCGAAGCTGAGCGTTTTGAGGTAGAAAGAGTCGCAGCCGAGCAGGCCGAAG
CTGCACGCATTGAGGCCGAGCAAGCTGAAGCTCAGAGATTAGCAGATGAGCAAGCGGCTCAGGTTGAAGCTCAGAGATTA
GCGGATGAGCAAGCGGCTCAGGTTGAAGCTCAAAGAGTTGCAGCAGAGCAGGCTGAAGCCCAGAGATTAGCAGGTGAGCA
AGCGGCTCAGGTTGAAGCTCAAAGAGTTGCTGCTGAGCAGGCTGAAGCCCAGAGATTAGCTGATGAGCAAGCAGGTCAAG
CCGAAGCTCAAAGAATTGAAGCCGAACGCCTTGAATCTGCACGTATCGAAGCAGAACAGGCTCGTTTAGCCGCTGAGCAA
GCCGAACAAGCACGCTTGGCAGCAGGGCAGGCTGCTCAAGTTGAAGAGGAACGTCTTGAATCTGCACGTATCGAAGCAGA
TAGAGTCGCAGCTGAACAAGCCGCACAAGCAGCTCAAGCCGAAGCTCAAAGAGTTGAAGCTGAACGTATCGAAGCTGAAC
GTCTTGAAGCAGAAAGAGTTGCAGCAGAAAGAGTTGTAGCAGAACAGGCTCGTTTAGCAGCTGAGCAAGCAGAAGCTGTG
CGTATCGAGCAAGAACGCCTAGAAGCTGAACGTCTTGAATCAGAAAGAGTCGCAGCAGAGCAGGCTCGTTTAGCAGCTGA
GCAAGCAGAAGCTGCGCGTATCGAGCAAGAACGCCTAGAAGCTGAACGTCTTGAATCAGAACGTCTTGAAGCAGAAAGAA
TTGCAGCAGAACAAGCCGAGGCTCAAAGAGTCGAAGCAGAAAGAATTGCAGCAGAAGCCGCTGCACAGCAAGCAGAAGAG
CAACAGCCAGAGCCACAGGCTAAGCCAGTAAAAGAAGGTTTGTTTGCCCGTCTTAAGCGTGGCCTAAAGCGTACCAGTGA
GAGTATTGGTAGCGGCTTTATTGGGTTGTTTAGCGGTAAGAAGATCGATGATGATCTTTTTGAAGAGTTAGAAGAACAGC
TATTGATCGCCGATGTGGGCGTCGAAACGACCACACGTTTGATTAAGAACCTAACTGAGCAGGCAAGCCGTAAGCAGCTA
AAAGATGGTGAAGCGCTATACGATCTTCTACGTGAAGAGATGCAAAAGACGCTAGACCCTGTATCTGTGCCACTGATCCC
TGAAAATGCCGATGGTCCATTTGTGATCTTAATGGTGGGTGTGAATGGTGTGGGTAAAACCACCACCATTGGTAAGCTGG
CTAAACAGTATCAGGAACAAGGTAAGTCGGTGATGTTGGCTGCGGGTGATACCTTCCGTGCCGCCGCTGTTGAGCAGCTG
CAAGTTTGGGGTCAACGTAACGATATTCCGGTTATTGCCCAGCATACTGGTGCTGACAGTGCATCAGTGTTATTTGACGC
ATTACAAGCGGCTCGTGCTCGTAATGTTGACGTACTGATTGCCGATACAGCTGGTCGTTTGCAGAACAAGGCTCATTTGA
TGGACGAACTGAAGAAAGTTGTCCGTGTGATGAAGAAGCAAGATGAAGCTGCCCCGCACGAGGTGATGTTAACCTTAGAT
GCGAGCACAGGTCAGAATGCGATTAGCCAGGCGCAACTGTTCCAAGAGGCTGTAGGTGTCACGGGTATTACTATCAGTAA
GCTAGACGGTACTGCTAAGGGCGGAGTGATCTTTGCTATTGCGGACAAGTTTGGTATTCCAATTCGTCATATCGGTGTTG
GTGAGCAGATCGACGACTTACGTACGTTCGATGCTAAAGACTTTATCGAAGCCTTGTTTAGCCAAACAAAAGACGACAAA
GACGCCAAATAA

Upstream 100 bases:

>100_bases
GTTTTTGCTGTTTTTATCAGCGTAATTTGAGCTGGATTTTGATATAACGTCCTCCACCCTAATGCATTTATGTACAGCTA
TTTGAGCACCGGTATAACAC

Downstream 100 bases:

>100_bases
CGTTAGCTTATACTCAGCGTTGCTGAAAAATAGCTAAAGATAAGCACCCCAAGGGGTGCTTTTATTAATGCCAACTAACA
AGAAATCTTATTAATGATTC

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MAKKGFFSWFRKDKSKEEAQAAEAAKLEAEKLELERIEAERFEVERVAAEQAEAARIEAEQAEAQRLADEQAAQVEAQRL
ADEQAAQVEAQRVAAEQAEAQRLAGEQAAQVEAQRVAAEQAEAQRLADEQAGQAEAQRIEAERLESARIEAEQARLAAEQ
AEQARLAAGQAAQVEEERLESARIEADRVAAEQAAQAAQAEAQRVEAERIEAERLEAERVAAERVVAEQARLAAEQAEAV
RIEQERLEAERLESERVAAEQARLAAEQAEAARIEQERLEAERLESERLEAERIAAEQAEAQRVEAERIAAEAAAQQAEE
QQPEPQAKPVKEGLFARLKRGLKRTSESIGSGFIGLFSGKKIDDDLFEELEEQLLIADVGVETTTRLIKNLTEQASRKQL
KDGEALYDLLREEMQKTLDPVSVPLIPENADGPFVILMVGVNGVGKTTTIGKLAKQYQEQGKSVMLAAGDTFRAAAVEQL
QVWGQRNDIPVIAQHTGADSASVLFDALQAARARNVDVLIADTAGRLQNKAHLMDELKKVVRVMKKQDEAAPHEVMLTLD
ASTGQNAISQAQLFQEAVGVTGITISKLDGTAKGGVIFAIADKFGIPIRHIGVGEQIDDLRTFDAKDFIEALFSQTKDDK
DAK

Sequences:

>Translated_643_residues
MAKKGFFSWFRKDKSKEEAQAAEAAKLEAEKLELERIEAERFEVERVAAEQAEAARIEAEQAEAQRLADEQAAQVEAQRL
ADEQAAQVEAQRVAAEQAEAQRLAGEQAAQVEAQRVAAEQAEAQRLADEQAGQAEAQRIEAERLESARIEAEQARLAAEQ
AEQARLAAGQAAQVEEERLESARIEADRVAAEQAAQAAQAEAQRVEAERIEAERLEAERVAAERVVAEQARLAAEQAEAV
RIEQERLEAERLESERVAAEQARLAAEQAEAARIEQERLEAERLESERLEAERIAAEQAEAQRVEAERIAAEAAAQQAEE
QQPEPQAKPVKEGLFARLKRGLKRTSESIGSGFIGLFSGKKIDDDLFEELEEQLLIADVGVETTTRLIKNLTEQASRKQL
KDGEALYDLLREEMQKTLDPVSVPLIPENADGPFVILMVGVNGVGKTTTIGKLAKQYQEQGKSVMLAAGDTFRAAAVEQL
QVWGQRNDIPVIAQHTGADSASVLFDALQAARARNVDVLIADTAGRLQNKAHLMDELKKVVRVMKKQDEAAPHEVMLTLD
ASTGQNAISQAQLFQEAVGVTGITISKLDGTAKGGVIFAIADKFGIPIRHIGVGEQIDDLRTFDAKDFIEALFSQTKDDK
DAK
>Mature_642_residues
AKKGFFSWFRKDKSKEEAQAAEAAKLEAEKLELERIEAERFEVERVAAEQAEAARIEAEQAEAQRLADEQAAQVEAQRLA
DEQAAQVEAQRVAAEQAEAQRLAGEQAAQVEAQRVAAEQAEAQRLADEQAGQAEAQRIEAERLESARIEAEQARLAAEQA
EQARLAAGQAAQVEEERLESARIEADRVAAEQAAQAAQAEAQRVEAERIEAERLEAERVAAERVVAEQARLAAEQAEAVR
IEQERLEAERLESERVAAEQARLAAEQAEAARIEQERLEAERLESERLEAERIAAEQAEAQRVEAERIAAEAAAQQAEEQ
QPEPQAKPVKEGLFARLKRGLKRTSESIGSGFIGLFSGKKIDDDLFEELEEQLLIADVGVETTTRLIKNLTEQASRKQLK
DGEALYDLLREEMQKTLDPVSVPLIPENADGPFVILMVGVNGVGKTTTIGKLAKQYQEQGKSVMLAAGDTFRAAAVEQLQ
VWGQRNDIPVIAQHTGADSASVLFDALQAARARNVDVLIADTAGRLQNKAHLMDELKKVVRVMKKQDEAAPHEVMLTLDA
STGQNAISQAQLFQEAVGVTGITISKLDGTAKGGVIFAIADKFGIPIRHIGVGEQIDDLRTFDAKDFIEALFSQTKDDKD
AK

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=273, Percent_Identity=30.7692307692308, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI226371618, Length=200, Percent_Identity=35, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI295424842, Length=233, Percent_Identity=32.618025751073, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI23308697, Length=233, Percent_Identity=32.618025751073, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=30.0699300699301, Blast_Score=73, Evalue=8e-13,
Organism=Escherichia coli, GI1789874, Length=324, Percent_Identity=77.1604938271605, Blast_Score=496, Evalue=1e-141,
Organism=Escherichia coli, GI1788963, Length=305, Percent_Identity=32.4590163934426, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=275, Percent_Identity=29.4545454545455, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI193206261, Length=312, Percent_Identity=29.1666666666667, Blast_Score=114, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=199, Percent_Identity=36.1809045226131, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320498, Length=314, Percent_Identity=28.0254777070064, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17647949, Length=276, Percent_Identity=29.7101449275362, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24641198, Length=225, Percent_Identity=29.7777777777778, Blast_Score=104, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 70445; Mature: 70314

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKGFFSWFRKDKSKEEAQAAEAAKLEAEKLELERIEAERFEVERVAAEQAEAARIEAE
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEAQRLADEQAAQVEAQRLADEQAAQVEAQRVAAEQAEAQRLAGEQAAQVEAQRVAAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAQRLADEQAGQAEAQRIEAERLESARIEAEQARLAAEQAEQARLAAGQAAQVEEERLE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SARIEADRVAAEQAAQAAQAEAQRVEAERIEAERLEAERVAAERVVAEQARLAAEQAEAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIEQERLEAERLESERVAAEQARLAAEQAEAARIEQERLEAERLESERLEAERIAAEQAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQRVEAERIAAEAAAQQAEEQQPEPQAKPVKEGLFARLKRGLKRTSESIGSGFIGLFSGK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
KIDDDLFEELEEQLLIADVGVETTTRLIKNLTEQASRKQLKDGEALYDLLREEMQKTLDP
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
VSVPLIPENADGPFVILMVGVNGVGKTTTIGKLAKQYQEQGKSVMLAAGDTFRAAAVEQL
CCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHH
QVWGQRNDIPVIAQHTGADSASVLFDALQAARARNVDVLIADTAGRLQNKAHLMDELKKV
HHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHH
VRVMKKQDEAAPHEVMLTLDASTGQNAISQAQLFQEAVGVTGITISKLDGTAKGGVIFAI
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEE
ADKFGIPIRHIGVGEQIDDLRTFDAKDFIEALFSQTKDDKDAK
ECCCCCCEEECCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AKKGFFSWFRKDKSKEEAQAAEAAKLEAEKLELERIEAERFEVERVAAEQAEAARIEAE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEAQRLADEQAAQVEAQRLADEQAAQVEAQRVAAEQAEAQRLAGEQAAQVEAQRVAAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAQRLADEQAGQAEAQRIEAERLESARIEAEQARLAAEQAEQARLAAGQAAQVEEERLE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SARIEADRVAAEQAAQAAQAEAQRVEAERIEAERLEAERVAAERVVAEQARLAAEQAEAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIEQERLEAERLESERVAAEQARLAAEQAEAARIEQERLEAERLESERLEAERIAAEQAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQRVEAERIAAEAAAQQAEEQQPEPQAKPVKEGLFARLKRGLKRTSESIGSGFIGLFSGK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
KIDDDLFEELEEQLLIADVGVETTTRLIKNLTEQASRKQLKDGEALYDLLREEMQKTLDP
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
VSVPLIPENADGPFVILMVGVNGVGKTTTIGKLAKQYQEQGKSVMLAAGDTFRAAAVEQL
CCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHH
QVWGQRNDIPVIAQHTGADSASVLFDALQAARARNVDVLIADTAGRLQNKAHLMDELKKV
HHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHH
VRVMKKQDEAAPHEVMLTLDASTGQNAISQAQLFQEAVGVTGITISKLDGTAKGGVIFAI
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEE
ADKFGIPIRHIGVGEQIDDLRTFDAKDFIEALFSQTKDDKDAK
ECCCCCCEEECCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]