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The map label for this gene is nahR [H]

Identifier: 157963751

GI number: 157963751

Start: 4789486

End: 4790418

Strand: Direct

Name: nahR [H]

Synonym: Spea_3940

Alternate gene names: 157963751

Gene position: 4789486-4790418 (Clockwise)

Preceding gene: 157963747

Following gene: 157963753

Centisome position: 92.56

GC content: 48.34

Gene sequence:

>933_bases
ATGGAATTAGAAGAGATCTATCGCCAAGATCTAAGCCTGCTTATTGCACTACAAATTTTGGTAGAAGAACGCAGCGTGAC
TCAAGCGGCTAAGCGCTTACATTTGAGCCAATCTGCAACCAGTCGCATTCTTGCGCGCCTTAGAGATATGCTCGACGATC
CGCTGTTCTCTCGTGTGGGTCAGCAGCTTGTACCAACCTCATTTGCACTCGAATGCTACCAACAGTTGCGCCAACCCACG
GGCCAACTCATTGAATTACTCACGCCTAAAGCCTTTGTGCCACAAGAGTGTCAGCAGCAGTTTTCTATCGCAGTGACCGA
TTATGCCATGCAGGCATTAATCCCTTTCATTCTGCCAATCATCTATAAAAAGGCACCACAGATCCGCCTCGAAATTGTGC
CAGTACAGCAAAAAGAGTTACAGGCACAGCTCAGTGTGAAAGGCGCAGATATGGCCGTTTGTAGAGCAATAGGTCAGACA
GGAAATTTACAGCAGACATTTCTCGGCAAAGTGGGAGTCAGCTGTTTATTGTCACCCAACCACCCACTGGCAAATAGCGA
TATCACTCTCGATGATTATCTGCATTACCCCCATGCCACCATTGCCATCAGTGATGGAGTGAAAGCCCTGCTCGACGATG
CCATAAGCCTATATCCAGCGCGTACCGAACTATTACGCACCCCACATCTGGATACTGCGCTGGCGTTGCAATCGGTTAAT
CCGCTGATTATTACCCTACCAGAAGGCATGGCCGAAATCGCCGCCCAGCGACATAAGCTCAAGGTAAAGCCTCTACCGTT
TAAGCTGCAAAGTTTAGACTACAAGTTGTTCTGGCATTCGCGCTGCGATCAAGACAAGGCGCAGAAATGGTTACGTGAAG
AGATAGCAACAGCGATCCAAGAGTTGTTATCGCAGACACCGCAAAATCTTTAA

Upstream 100 bases:

>100_bases
ACACAGGAACTCGCGCCGAAAAAGCGCTAAACTCTCACACAGCAATCATGACTTTATACTGATTAGTATCATAAGCACTC
ACCGGAAAAGCCGACAAATT

Downstream 100 bases:

>100_bases
TGAACTAAAAGCAAGGTACTAGATCCTAGGACGCTACGCTGCGAGGACGGGCTGCGCCCTGCGAGGAACAGCAAAAGCAA
AAAAACACCGTCTTTGCATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MELEEIYRQDLSLLIALQILVEERSVTQAAKRLHLSQSATSRILARLRDMLDDPLFSRVGQQLVPTSFALECYQQLRQPT
GQLIELLTPKAFVPQECQQQFSIAVTDYAMQALIPFILPIIYKKAPQIRLEIVPVQQKELQAQLSVKGADMAVCRAIGQT
GNLQQTFLGKVGVSCLLSPNHPLANSDITLDDYLHYPHATIAISDGVKALLDDAISLYPARTELLRTPHLDTALALQSVN
PLIITLPEGMAEIAAQRHKLKVKPLPFKLQSLDYKLFWHSRCDQDKAQKWLREEIATAIQELLSQTPQNL

Sequences:

>Translated_310_residues
MELEEIYRQDLSLLIALQILVEERSVTQAAKRLHLSQSATSRILARLRDMLDDPLFSRVGQQLVPTSFALECYQQLRQPT
GQLIELLTPKAFVPQECQQQFSIAVTDYAMQALIPFILPIIYKKAPQIRLEIVPVQQKELQAQLSVKGADMAVCRAIGQT
GNLQQTFLGKVGVSCLLSPNHPLANSDITLDDYLHYPHATIAISDGVKALLDDAISLYPARTELLRTPHLDTALALQSVN
PLIITLPEGMAEIAAQRHKLKVKPLPFKLQSLDYKLFWHSRCDQDKAQKWLREEIATAIQELLSQTPQNL
>Mature_310_residues
MELEEIYRQDLSLLIALQILVEERSVTQAAKRLHLSQSATSRILARLRDMLDDPLFSRVGQQLVPTSFALECYQQLRQPT
GQLIELLTPKAFVPQECQQQFSIAVTDYAMQALIPFILPIIYKKAPQIRLEIVPVQQKELQAQLSVKGADMAVCRAIGQT
GNLQQTFLGKVGVSCLLSPNHPLANSDITLDDYLHYPHATIAISDGVKALLDDAISLYPARTELLRTPHLDTALALQSVN
PLIITLPEGMAEIAAQRHKLKVKPLPFKLQSLDYKLFWHSRCDQDKAQKWLREEIATAIQELLSQTPQNL

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=294, Percent_Identity=24.8299319727891, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790147, Length=297, Percent_Identity=27.6094276094276, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789204, Length=227, Percent_Identity=25.9911894273128, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081766, Length=132, Percent_Identity=30.3030303030303, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34847; Mature: 34847

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEEIYRQDLSLLIALQILVEERSVTQAAKRLHLSQSATSRILARLRDMLDDPLFSRVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QQLVPTSFALECYQQLRQPTGQLIELLTPKAFVPQECQQQFSIAVTDYAMQALIPFILPI
HHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IYKKAPQIRLEIVPVQQKELQAQLSVKGADMAVCRAIGQTGNLQQTFLGKVGVSCLLSPN
HHCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCHHEEECCC
HPLANSDITLDDYLHYPHATIAISDGVKALLDDAISLYPARTELLRTPHLDTALALQSVN
CCCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHCCC
PLIITLPEGMAEIAAQRHKLKVKPLPFKLQSLDYKLFWHSRCDQDKAQKWLREEIATAIQ
CEEEECCCHHHHHHHHHHCCCCCCCCEEHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHH
ELLSQTPQNL
HHHHHCCCCC
>Mature Secondary Structure
MELEEIYRQDLSLLIALQILVEERSVTQAAKRLHLSQSATSRILARLRDMLDDPLFSRVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QQLVPTSFALECYQQLRQPTGQLIELLTPKAFVPQECQQQFSIAVTDYAMQALIPFILPI
HHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IYKKAPQIRLEIVPVQQKELQAQLSVKGADMAVCRAIGQTGNLQQTFLGKVGVSCLLSPN
HHCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCHHEEECCC
HPLANSDITLDDYLHYPHATIAISDGVKALLDDAISLYPARTELLRTPHLDTALALQSVN
CCCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHCCC
PLIITLPEGMAEIAAQRHKLKVKPLPFKLQSLDYKLFWHSRCDQDKAQKWLREEIATAIQ
CEEEECCCHHHHHHHHHHCCCCCCCCEEHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHH
ELLSQTPQNL
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]