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The map label for this gene is fieF [H]

Identifier: 157963742

GI number: 157963742

Start: 4779643

End: 4780512

Strand: Reverse

Name: fieF [H]

Synonym: Spea_3931

Alternate gene names: 157963742

Gene position: 4780512-4779643 (Counterclockwise)

Preceding gene: 157963743

Following gene: 157963738

Centisome position: 92.38

GC content: 49.66

Gene sequence:

>870_bases
ATGAATGACACTTCCCAATACGATTTCTGGGTTAAGTTGGCCAGCCGTGCAGCGGTTGCGACAGCCTTAACCCTTATTAT
CATCAAGCTTGCGGCATGGATGTATTCTGGCTCGGCCAGTATGTTGGCATCTTTGACCGACTCTTTTGCCGATGCCTTGG
CCTCAATCGTCAATTTCATTGCGATTCGTTATGCCATCGTGCCCGCCGATCAGGAACATCGTTATGGTCACGGTAAAGCC
GAGCCTCTAGCGTCGTTGGCGCAATCGGCCTTTATTCTAGGCTCCGCATTTTTGCTGTTTTTCCACGGTGGCGAGCGATT
GATTAATCCGGTAGAGGTAAAACATGCCACCTTGGGTGTGATTGTCTCGGTTATCGCGATTGTGCTGACCTTTGCCCTAG
TGATGCTTCAGAAAAGAGCTTTAGCGGCGACATCGAGTACTGTGGTTGAGGCTGACTCGCTGCATTATAAGTCGGACCTA
TTTTTGAATGCCGCTGTATTACTGGCGCTTATCCTGTCTCAATATGGCTGGTGGTGGGCCGATGGTCTGTTTGCCGTGCT
TATCGCGCTATTTATTGGCCAGCAAGCGATTGGATTAGCTTACCGCTCGGTGCAGTCGCTATTAGATAGAGAGCTTGATG
ATGAGACCCGAGAGAAAATCGCTGAAATTGCCAAGTACGATCCTCAGGTGAGAGGCATCCACGACTTACGTACTCGTGAG
TCGGGTAAGACGATGTTTATTCAGTTCCACCTAGAACTGGATGGCGATTTGAGCTTACATGAGGCTCATAAAATTGCCGT
TGAAACCTCCGAGCGAGTGCGGCAAGAGTTTGTCGACTCGGAGGTGATTATTCACCAAGATCCCGTGTAG

Upstream 100 bases:

>100_bases
GATTGATTGGTAGTAACTTGAGGGAAATCATCCGATTTTCCCTCAAGTTGTTATAAACTTAGGATCTGTGTTTCCCTTAC
TTTATCAGTAAACAGATTTT

Downstream 100 bases:

>100_bases
CGGTTTGCGTATAAGCAAAAAAGGAGAGCCTGTGGCTCTCCTTTTTTTCAGTCGCTATTGAAGGGCCTCTAATCCATTTC
TAGCTCTTTTAATTTACGGG

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNDTSQYDFWVKLASRAAVATALTLIIIKLAAWMYSGSASMLASLTDSFADALASIVNFIAIRYAIVPADQEHRYGHGKA
EPLASLAQSAFILGSAFLLFFHGGERLINPVEVKHATLGVIVSVIAIVLTFALVMLQKRALAATSSTVVEADSLHYKSDL
FLNAAVLLALILSQYGWWWADGLFAVLIALFIGQQAIGLAYRSVQSLLDRELDDETREKIAEIAKYDPQVRGIHDLRTRE
SGKTMFIQFHLELDGDLSLHEAHKIAVETSERVRQEFVDSEVIIHQDPV

Sequences:

>Translated_289_residues
MNDTSQYDFWVKLASRAAVATALTLIIIKLAAWMYSGSASMLASLTDSFADALASIVNFIAIRYAIVPADQEHRYGHGKA
EPLASLAQSAFILGSAFLLFFHGGERLINPVEVKHATLGVIVSVIAIVLTFALVMLQKRALAATSSTVVEADSLHYKSDL
FLNAAVLLALILSQYGWWWADGLFAVLIALFIGQQAIGLAYRSVQSLLDRELDDETREKIAEIAKYDPQVRGIHDLRTRE
SGKTMFIQFHLELDGDLSLHEAHKIAVETSERVRQEFVDSEVIIHQDPV
>Mature_289_residues
MNDTSQYDFWVKLASRAAVATALTLIIIKLAAWMYSGSASMLASLTDSFADALASIVNFIAIRYAIVPADQEHRYGHGKA
EPLASLAQSAFILGSAFLLFFHGGERLINPVEVKHATLGVIVSVIAIVLTFALVMLQKRALAATSSTVVEADSLHYKSDL
FLNAAVLLALILSQYGWWWADGLFAVLIALFIGQQAIGLAYRSVQSLLDRELDDETREKIAEIAKYDPQVRGIHDLRTRE
SGKTMFIQFHLELDGDLSLHEAHKIAVETSERVRQEFVDSEVIIHQDPV

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Homo sapiens, GI57164948, Length=250, Percent_Identity=26.8, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1790349, Length=265, Percent_Identity=49.4339622641509, Blast_Score=260, Evalue=6e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 31914; Mature: 31914

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTSQYDFWVKLASRAAVATALTLIIIKLAAWMYSGSASMLASLTDSFADALASIVNFI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADQEHRYGHGKAEPLASLAQSAFILGSAFLLFFHGGERLINPVEVKHATLGV
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCHHHCCHHHHHHHHHHH
IVSVIAIVLTFALVMLQKRALAATSSTVVEADSLHYKSDLFLNAAVLLALILSQYGWWWA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHEEHHCCHHHHHHHHHHHHHHHHHHHHCCHHHH
DGLFAVLIALFIGQQAIGLAYRSVQSLLDRELDDETREKIAEIAKYDPQVRGIHDLRTRE
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHCC
SGKTMFIQFHLELDGDLSLHEAHKIAVETSERVRQEFVDSEVIIHQDPV
CCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
>Mature Secondary Structure
MNDTSQYDFWVKLASRAAVATALTLIIIKLAAWMYSGSASMLASLTDSFADALASIVNFI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADQEHRYGHGKAEPLASLAQSAFILGSAFLLFFHGGERLINPVEVKHATLGV
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCHHHCCHHHHHHHHHHH
IVSVIAIVLTFALVMLQKRALAATSSTVVEADSLHYKSDLFLNAAVLLALILSQYGWWWA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHEEHHCCHHHHHHHHHHHHHHHHHHHHCCHHHH
DGLFAVLIALFIGQQAIGLAYRSVQSLLDRELDDETREKIAEIAKYDPQVRGIHDLRTRE
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHCC
SGKTMFIQFHLELDGDLSLHEAHKIAVETSERVRQEFVDSEVIIHQDPV
CCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA