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The map label for this gene is uxaA [H]

Identifier: 157963666

GI number: 157963666

Start: 4684997

End: 4686178

Strand: Reverse

Name: uxaA [H]

Synonym: Spea_3855

Alternate gene names: 157963666

Gene position: 4686178-4684997 (Counterclockwise)

Preceding gene: 157963667

Following gene: 157963665

Centisome position: 90.56

GC content: 48.56

Gene sequence:

>1182_bases
ATGATGAATAGCTTTATTGGTTTTGGCCGTACAGACGGCAGCGTGGGTATTCGTAATCATGTATTGATTATGGCGGTAGA
TGAATGTTGTGATGGCATAGCTCGTGCCATTGCCGACAGTATCGATAACGGTATCGTGGTCACTAACTACAACACCTGTA
TGTATGGTGGTAACGAAGAGATGATCAACACCATGATCCATACGGGCAATAACCCGAATGTGGCCGGTGTGCTGGTACTC
GCCATGGGCTGTGGCAGTATCGATCCTGAAATCGTAGCTGCACCAATTCGTGAAACTGGCCGACCTGCGTTTTCATTAGT
GTGCATGAAACAGCAAGGCACCCGCGCCACGATTAACCAAGGTAAAGAATTAGCGCAGCAACTACAGCAAGCAGCACAAG
ACGCTCCTCGCGTAGAAAAGCCGATCTCAGAGCTGATCATCGGTGTTAAGTGCGGCGGTTCTGATACTAGCTCGGGCATT
GCTTCAAACCCGAGTGTTGGCCGAGCAGTCGACACCTTAGTCGATATGGGCGCAACCGCCATTGCCGGTGAGCTTATCGA
ATTAGTCGGTTGCGAATCCATTTTACGTCAGCGCGCGGTTAGCACTGAGGTGGCCGATAAATTAGAACGCTTAATCCATC
AAGAAGAGGCGCGTTGGCATGTTGACGGCGCAGAAGTAGAAACCATGAGTATTGGTAACAGTGTCGGTGGCCTTACTACA
TTAGAAGAGAAGTCTTTTGGTGCACTGAGCAAAACCGGTACTCGTGCAATTCAAGATGTATTGCAGATTAATCATCTAGT
CCATGAAAAGCCGACCACAGCGGGTTTCTATCTGTCGGAAGCCACTCACCTATGTGGCAGCGCAGGTATGCACTTTGCGG
CACTGGGCGCGCATCTGATTTTATGGACTACCGGCGGCGCAGGCTTTAATAACCCTATCGTGCCAGTGATCCGTGTGAGC
GGTAACCAATATTTGTTAAATGAAGATATAGATATTGACGCATCTGGTATCATGCGCGCCGAAGAAGGTGTAGAAAGTGT
AGCTGAGCGCATCGTGGCCAAAGTTAGCAAGGTTGCCCAAGGCCAGCAGACCAATATTGAAGAGATAGGTTACAGCTATT
GTAGCTTGTATCAAAAAGACCAACGCTTAGAAACAGTATTACGTTTTAAGCCAGGCTGTTAA

Upstream 100 bases:

>100_bases
GTGGTGAGTTAGCTCATGTGCAAAATGTGCGTAGCCAACGATTAGATATTCCCGACAACATCATTCAAGAAATTATTAAA
CAGATGCGGATTGAACAAGC

Downstream 100 bases:

>100_bases
GCTTTTTCAACGTCTAGCCGCTAAGCGCTAGTAGCTAGTTAAGCATCGCCCTTATACTTATATAGGTTTAAGGGCTTACC
ATCGCAGGATGTTATGAATA

Product: D-galactarate dehydratase/Altronate hydrolase domain-containing protein

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MMNSFIGFGRTDGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEEMINTMIHTGNNPNVAGVLVL
AMGCGSIDPEIVAAPIRETGRPAFSLVCMKQQGTRATINQGKELAQQLQQAAQDAPRVEKPISELIIGVKCGGSDTSSGI
ASNPSVGRAVDTLVDMGATAIAGELIELVGCESILRQRAVSTEVADKLERLIHQEEARWHVDGAEVETMSIGNSVGGLTT
LEEKSFGALSKTGTRAIQDVLQINHLVHEKPTTAGFYLSEATHLCGSAGMHFAALGAHLILWTTGGAGFNNPIVPVIRVS
GNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVSKVAQGQQTNIEEIGYSYCSLYQKDQRLETVLRFKPGC

Sequences:

>Translated_393_residues
MMNSFIGFGRTDGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEEMINTMIHTGNNPNVAGVLVL
AMGCGSIDPEIVAAPIRETGRPAFSLVCMKQQGTRATINQGKELAQQLQQAAQDAPRVEKPISELIIGVKCGGSDTSSGI
ASNPSVGRAVDTLVDMGATAIAGELIELVGCESILRQRAVSTEVADKLERLIHQEEARWHVDGAEVETMSIGNSVGGLTT
LEEKSFGALSKTGTRAIQDVLQINHLVHEKPTTAGFYLSEATHLCGSAGMHFAALGAHLILWTTGGAGFNNPIVPVIRVS
GNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVSKVAQGQQTNIEEIGYSYCSLYQKDQRLETVLRFKPGC
>Mature_393_residues
MMNSFIGFGRTDGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEEMINTMIHTGNNPNVAGVLVL
AMGCGSIDPEIVAAPIRETGRPAFSLVCMKQQGTRATINQGKELAQQLQQAAQDAPRVEKPISELIIGVKCGGSDTSSGI
ASNPSVGRAVDTLVDMGATAIAGELIELVGCESILRQRAVSTEVADKLERLIHQEEARWHVDGAEVETMSIGNSVGGLTT
LEEKSFGALSKTGTRAIQDVLQINHLVHEKPTTAGFYLSEATHLCGSAGMHFAALGAHLILWTTGGAGFNNPIVPVIRVS
GNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVSKVAQGQQTNIEEIGYSYCSLYQKDQRLETVLRFKPGC

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=400, Percent_Identity=28.25, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789516, Length=402, Percent_Identity=28.6069651741293, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 41848; Mature: 41848

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNSFIGFGRTDGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEE
CCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHH
MINTMIHTGNNPNVAGVLVLAMGCGSIDPEIVAAPIRETGRPAFSLVCMKQQGTRATINQ
HHHHHHHCCCCCCHHHHHHEECCCCCCCHHHEECCHHHCCCCEEEEEEECCCCCHHHHHH
GKELAQQLQQAAQDAPRVEKPISELIIGVKCGGSDTSSGIASNPSVGRAVDTLVDMGATA
HHHHHHHHHHHHHCCCHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHH
IAGELIELVGCESILRQRAVSTEVADKLERLIHQEEARWHVDGAEVETMSIGNSVGGLTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEEECCCCCCCCEE
LEEKSFGALSKTGTRAIQDVLQINHLVHEKPTTAGFYLSEATHLCGSAGMHFAALGAHLI
ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCEEE
LWTTGGAGFNNPIVPVIRVSGNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVSKVAQ
EEECCCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQQTNIEEIGYSYCSLYQKDQRLETVLRFKPGC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMNSFIGFGRTDGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEE
CCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHH
MINTMIHTGNNPNVAGVLVLAMGCGSIDPEIVAAPIRETGRPAFSLVCMKQQGTRATINQ
HHHHHHHCCCCCCHHHHHHEECCCCCCCHHHEECCHHHCCCCEEEEEEECCCCCHHHHHH
GKELAQQLQQAAQDAPRVEKPISELIIGVKCGGSDTSSGIASNPSVGRAVDTLVDMGATA
HHHHHHHHHHHHHCCCHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHH
IAGELIELVGCESILRQRAVSTEVADKLERLIHQEEARWHVDGAEVETMSIGNSVGGLTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEEECCCCCCCCEE
LEEKSFGALSKTGTRAIQDVLQINHLVHEKPTTAGFYLSEATHLCGSAGMHFAALGAHLI
ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCEEE
LWTTGGAGFNNPIVPVIRVSGNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVSKVAQ
EEECCCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQQTNIEEIGYSYCSLYQKDQRLETVLRFKPGC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]