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The map label for this gene is recQ [H]

Identifier: 157963641

GI number: 157963641

Start: 4657473

End: 4659296

Strand: Reverse

Name: recQ [H]

Synonym: Spea_3830

Alternate gene names: 157963641

Gene position: 4659296-4657473 (Counterclockwise)

Preceding gene: 157963644

Following gene: 157963639

Centisome position: 90.04

GC content: 49.62

Gene sequence:

>1824_bases
ATGGATCAGGCGGCGCTCGATACTTCAGTCGATCAATTATCTTCCACCCTTCAGTCGGTATTTGGTTACCGTACTTTCAG
AGAAGGTCAGAGGGAGGTCATTGAGCAGATCTGCGCAGGACAAGATTGCCTGGTGATCATGCCGACAGGTGGCGGTAAAA
GCCTGTGTTATCAATTACCCGCTCTAGTCTTACCCGGTTTAACCGTGGTGGTTTCTCCCCTGATCTCGCTAATGAAAGAT
CAGGTCGATAGCCTTATCCAGACCGGAGTGTCTGCGGCTTACTTAAATTCCTCTCTGCCTAGAGAAGAGAGCCTGCAGGT
GTTGCAGAAGATGCGTTATGGCGAACTTAAGTTGCTGTATGTGTCGCCTGAGCGCCTGTTGCAGGCGAGCTTTATCGACA
GGCTACATGAGCTTAATGTATCTTTATTTGCTATCGATGAGGCGCACTGTATCTCGCAATGGGGTCATGACTTTAGACCC
GAATATGCCGCATTAGGCCGCTTACGTCAGCAGTTTCCGCAAGTGCCGATTATGGCACTGACCGCGACAGCCGATAAGGC
TACACGAGCCGATATTTGCGAGCGTTTAACCATTACACCGCACTCTTTACTGACCAGTTTCGATCGACCTAATATTCGCT
ATACCGTGGCTGAAAAGCTTAATGCAGCTAATCAGTTGCGTCAGTTTGTCGATGCGCAAAATGGGGCCAGTGGTATTGTC
TATTGCAGCAGTCGCCGTCGAGTCGATGAGGTTGCCGAGCGCTTGCGCTTGCAAGGCCATCAAGCCGAAGCCTACCATGC
GGGTAAGACTCAAGAAGAGCGCGCTGAAGTTCAGGATAAATTTCTAAAAGATCAGCTAGATATTGTTGTGGCAACAGTGG
CGTTTGGTATGGGAATTAACAAGTCGAATGTACGCTATGTGGTGCATTACGATATTCCTAAGAGTGTTGAGTCCTATTAC
CAAGAAACTGGCCGTGCGGGTCGTGATGGCTTGGACTCGGAGGCGTTAATGCTATTTGACCCTGCCGATATCGGCCGAGT
TAGACACTTAATCGAGCAGTCAGAGCCGGGTCCACAGCAACAGGTGGAGTTTCATAAGCTTAATACCATGGCCGCCTTTG
CCGAGGCGCAGACCTGTCGTCGACAAGTGCTGTTGCACTATTTCGATGAACCTGCGCTTAAGGCGTGCGGTAACTGCGAT
ATCTGTTTAGACCCGCCTAAGAAATACAACGGTATTCAAGATGCACAAAAGGTGTTGTCTTGTATCTATCGCATCGGTCA
GCGCTTTGGCATTAATCATCTTATTGAAGTGCTGCGTGGTTCAAAGTCGGCCAGCGTGATTGAGCGTGGGCATGACAAGT
TATCTACCTGGGGCATTGGCAAAGAAAAGAGCCACGAGCATTGGCTTAGTGTGATCCGCCAGTTGATCCATTTAGGTCTT
GCCACCCAAGACATCACCCGCGGATCTTCGGTAACCCTTAATTCGTCTGCACGTGCCGTGTTAAAGGGGGAGGTTGAGTT
ACTGCTGGCTGAGCCTAGAATCGTGATTCAAACGACTAAGCGTCGCAGTAATAACCCGCGTGCACCACTCAATTACGACC
GTAAGCTATTTGCAAGATTAAAGCTTTTACGCCGTACGTTGGCCGAAGAGTTAGATGTGCCGCCTTACTTGGTATTTAAC
GATGCGACTTTAGCGGAAATGGCTGCAATACTACCGACAAGTCCGGGTGAAATGTTGGCTGTTAACGGTGTCGGTGAGCG
CAAGCTCGAACGTTTTGGTGGTGAGTTCCTCGATGAGATCGCCGATTATCTAGCGGAAGGTTAA

Upstream 100 bases:

>100_bases
GAGGCGCAAGCTTAAATTTTACTCAACAGTGTTGTTCGAGAGAGACAAGAGCCTCCGCCTCTATTAGAATAGTCGACCCA
ATTTTTAACACAGGTTCATT

Downstream 100 bases:

>100_bases
TGCAAAGAAGGCGAGTCCAGAGAATGCTTGTTATAGATAAACGGCTTAGCTGTATAATTGGCCCTTTAAGATCCTGACTT
TCTTGATGGCTGATACTGCC

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MDQAALDTSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLPALVLPGLTVVVSPLISLMKD
QVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLYVSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRP
EYAALGRLRQQFPQVPIMALTATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGASGIV
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERAEVQDKFLKDQLDIVVATVAFGMGINKSNVRYVVHYDIPKSVESYY
QETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQQVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCD
ICLDPPKKYNGIQDAQKVLSCIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
ATQDITRGSSVTLNSSARAVLKGEVELLLAEPRIVIQTTKRRSNNPRAPLNYDRKLFARLKLLRRTLAEELDVPPYLVFN
DATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEIADYLAEG

Sequences:

>Translated_607_residues
MDQAALDTSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLPALVLPGLTVVVSPLISLMKD
QVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLYVSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRP
EYAALGRLRQQFPQVPIMALTATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGASGIV
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERAEVQDKFLKDQLDIVVATVAFGMGINKSNVRYVVHYDIPKSVESYY
QETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQQVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCD
ICLDPPKKYNGIQDAQKVLSCIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
ATQDITRGSSVTLNSSARAVLKGEVELLLAEPRIVIQTTKRRSNNPRAPLNYDRKLFARLKLLRRTLAEELDVPPYLVFN
DATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEIADYLAEG
>Mature_607_residues
MDQAALDTSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLPALVLPGLTVVVSPLISLMKD
QVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLYVSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRP
EYAALGRLRQQFPQVPIMALTATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGASGIV
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERAEVQDKFLKDQLDIVVATVAFGMGINKSNVRYVVHYDIPKSVESYY
QETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQQVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCD
ICLDPPKKYNGIQDAQKVLSCIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
ATQDITRGSSVTLNSSARAVLKGEVELLLAEPRIVIQTTKRRSNNPRAPLNYDRKLFARLKLLRRTLAEELDVPPYLVFN
DATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEIADYLAEG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=629, Percent_Identity=35.7710651828299, Blast_Score=353, Evalue=2e-97,
Organism=Homo sapiens, GI110735439, Length=505, Percent_Identity=36.6336633663366, Blast_Score=311, Evalue=1e-84,
Organism=Homo sapiens, GI169218196, Length=502, Percent_Identity=36.8525896414343, Blast_Score=311, Evalue=2e-84,
Organism=Homo sapiens, GI14591902, Length=458, Percent_Identity=38.4279475982533, Blast_Score=301, Evalue=2e-81,
Organism=Homo sapiens, GI14591904, Length=458, Percent_Identity=38.4279475982533, Blast_Score=301, Evalue=2e-81,
Organism=Homo sapiens, GI148612816, Length=424, Percent_Identity=38.2075471698113, Blast_Score=272, Evalue=7e-73,
Organism=Homo sapiens, GI51242947, Length=363, Percent_Identity=40.495867768595, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI51242943, Length=363, Percent_Identity=40.495867768595, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI284005309, Length=366, Percent_Identity=38.5245901639344, Blast_Score=222, Evalue=8e-58,
Organism=Homo sapiens, GI148613856, Length=339, Percent_Identity=25.9587020648968, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI38201710, Length=339, Percent_Identity=25.9587020648968, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4758138, Length=337, Percent_Identity=24.6290801186944, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI222352149, Length=330, Percent_Identity=21.5151515151515, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI21071032, Length=92, Percent_Identity=34.7826086956522, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4758112, Length=327, Percent_Identity=25.9938837920489, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI18375623, Length=327, Percent_Identity=25.9938837920489, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI7661920, Length=348, Percent_Identity=21.264367816092, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI48994977, Length=583, Percent_Identity=59.1766723842196, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI87082221, Length=339, Percent_Identity=25.9587020648968, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787016, Length=351, Percent_Identity=24.5014245014245, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788930, Length=338, Percent_Identity=25.1479289940828, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790214, Length=113, Percent_Identity=27.4336283185841, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=655, Percent_Identity=33.7404580152672, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI32564293, Length=690, Percent_Identity=31.304347826087, Blast_Score=306, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI71987997, Length=408, Percent_Identity=38.2352941176471, Blast_Score=285, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI71987993, Length=408, Percent_Identity=38.2352941176471, Blast_Score=285, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17552866, Length=462, Percent_Identity=35.7142857142857, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17537549, Length=370, Percent_Identity=21.8918918918919, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71987143, Length=344, Percent_Identity=22.093023255814, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=531, Percent_Identity=36.1581920903955, Blast_Score=321, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6324217, Length=336, Percent_Identity=25.5952380952381, Blast_Score=90, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6320224, Length=353, Percent_Identity=21.2464589235127, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325138, Length=140, Percent_Identity=27.1428571428571, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324778, Length=164, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322427, Length=406, Percent_Identity=24.384236453202, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320041, Length=336, Percent_Identity=22.6190476190476, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646066, Length=633, Percent_Identity=33.175355450237, Blast_Score=336, Evalue=3e-92,
Organism=Drosophila melanogaster, GI24664226, Length=447, Percent_Identity=35.5704697986577, Blast_Score=275, Evalue=8e-74,
Organism=Drosophila melanogaster, GI62472181, Length=447, Percent_Identity=35.5704697986577, Blast_Score=272, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24664230, Length=447, Percent_Identity=35.5704697986577, Blast_Score=271, Evalue=7e-73,
Organism=Drosophila melanogaster, GI21358123, Length=377, Percent_Identity=36.8700265251989, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI28574962, Length=343, Percent_Identity=27.1137026239067, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18857967, Length=357, Percent_Identity=25.7703081232493, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281361218, Length=341, Percent_Identity=22.2873900293255, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644481, Length=341, Percent_Identity=22.2873900293255, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644479, Length=341, Percent_Identity=22.2873900293255, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644483, Length=341, Percent_Identity=22.2873900293255, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644487, Length=341, Percent_Identity=22.2873900293255, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45551833, Length=341, Percent_Identity=22.2873900293255, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644485, Length=341, Percent_Identity=22.2873900293255, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17977678, Length=344, Percent_Identity=23.2558139534884, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355075, Length=347, Percent_Identity=20.1729106628242, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24645031, Length=123, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 67817; Mature: 67817

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQAALDTSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
ALVLPGLTVVVSPLISLMKDQVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
VSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRPEYAALGRLRQQFPQVPIMAL
ECHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEE
TATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGASGIV
EECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEE
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERAEVQDKFLKDQLDIVVATVAFGMGIN
EECCCCCHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KSNVRYVVHYDIPKSVESYYQETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQ
CCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHH
QVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCDICLDPPKKYNGIQDAQKVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCCHHCCCHHHHHHHHH
CIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
ATQDITRGSSVTLNSSARAVLKGEVELLLAEPRIVIQTTKRRSNNPRAPLNYDRKLFARL
CHHHHCCCCCEEECCCCCHHEECCEEEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHH
KLLRRTLAEELDVPPYLVFNDATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEI
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
ADYLAEG
HHHHCCC
>Mature Secondary Structure
MDQAALDTSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
ALVLPGLTVVVSPLISLMKDQVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
VSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRPEYAALGRLRQQFPQVPIMAL
ECHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEE
TATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGASGIV
EECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEE
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERAEVQDKFLKDQLDIVVATVAFGMGIN
EECCCCCHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KSNVRYVVHYDIPKSVESYYQETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQ
CCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHH
QVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCDICLDPPKKYNGIQDAQKVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCCHHCCCHHHHHHHHH
CIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
ATQDITRGSSVTLNSSARAVLKGEVELLLAEPRIVIQTTKRRSNNPRAPLNYDRKLFARL
CHHHHCCCCCEEECCCCCHHEECCEEEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHH
KLLRRTLAEELDVPPYLVFNDATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEI
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
ADYLAEG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]