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The map label for this gene is argS [H]

Identifier: 157963591

GI number: 157963591

Start: 4594763

End: 4596508

Strand: Direct

Name: argS [H]

Synonym: Spea_3779

Alternate gene names: 157963591

Gene position: 4594763-4596508 (Clockwise)

Preceding gene: 157963590

Following gene: 157963592

Centisome position: 88.79

GC content: 46.33

Gene sequence:

>1746_bases
ATGAAATCACATACTCAATCTTTACTCGCTGAATCTTTAAATGCCCTTAAACAACAAGGGATTGTTCCTGCAGATTTTGA
AGCTCGTATTCAAGTCGACCGAACGAAAGATAAAAGCCACGGTGATTTTGCAACTAACTTGGCAATGATGCTAACTAAAG
CTGCGGGCAAGAATCCACGTGAACTAGCCCAACTGCTTATCGATAACCTGCCTGAATCTAGCCATGTTGAGAAAGTTGAA
ATAGCAGGCCCAGGCTTTATCAACTTCTTTATCGATGATAATGCCCTAGCCAATCAGCTTATGGCTGCGCTTAACAGCGA
CACATTAGGTATCGAACTGCCAGCATCACAAACTGTAGTTGTCGATTACTCTTCGCCAAACTTAGCCAAAGAGATGCACG
TAGGTCACCTACGTTCAACCATTATCGGTGACAGTGTGGTGCGCGCCCTTGAATTTATGGGTCACAAAGTTATTCGTCAA
AACCACGTGGGCGACTGGGGAACTCAGTTCGGTATGCTACTTGCCTATATGGAAGAGCTTCGCGCTGCCAATGGCGAGCA
AGCCAAAATGGAGCTGTCTGATCTAGAGACATTCTACCGCGCCGCTAAAGTCCGCTTCGACGAGTCTGAAGAGTTCGCTA
CCCGCGCACGTAAGCTTGTTGTTGCACTGCAATCGGGCGACGAGTACTGCAATAAACTGTGGCGCGAATTTAACGATATC
TCACTAAGCCATTGTCATGAGCTGTATGAGCGTCTAGGCGTAAGCTTGACTCGCGCTGATGTTCGCGGCGAAAGCGCTTA
TAACAGTGACCTTGCACAAGTGGTTGCTGACTTAGATTCACAAGGTCTATTGTCTGAAAGCAACGGCGCAAAAGTTGTTT
TCCAAGACGAATTTAAAAATAAAGAAGGCGAGCCTCTACCGGTTATTATTCAAAAAGCCGATGGAGGTTACCTATATGCC
ACCAGCGATTTAGCCGCGATGCGCTATCGCTCAAATGTACTAAACGCTGACCGCGCACTGTACTTCGTAGATTTACGTCA
GGCGTTACACTTCCAGCAAGTATTTAAGCTAGCTAAAACTGCTAAATTTGTTCGCGAAGAGATGAGCTTCGAGCACATGG
GCTTTGGCACCATGAACGGCGAAGATGGTCGTCCATTTAAGACACGTTCTGGCGGTGTGGTTAAGCTTATTGATTTGTTA
AAAGAAGCCGATATTCGTGCACTTGACCTTGTTCGCAGCAAAAATCCAGATATGGATGAAGCTGAACTTGCTGAGATTGC
TCGTGTTGTAGGTATCGCCTCTGTTAAATACGCCGATCTTTCTAAGAACCGTGCTAGCGATTACATCTTTAGCTTTGAGC
AGATGCTGAGCTTTGAAGGCAACACTGCACCTTACCTACTTTACGCCTACACCCGTGTAGCGGGTATCTTCAAGCGTGCT
CAAGACGTTGATTTAAGCGATGCGAAAATCATTCTAGAGCACGAGAAAGAGAAAGACCTAGGTACTAAACTGGCACAGTT
TGGCGAAGTCATGGCTCGTATGGTTAGCAAAGGCCAGCCACACGCCCTTTGCGGTTACCTGTTCGAACTTGCTGGCGCCT
TCTCTAGTTTCTACGAAGCTTGCCCTGTATTGGCCGCAGAAACAGAAGAGCTGAAGAAGAGCCGTTTACTATTGTCGCAG
CTTACTGCTAAGACACTAAAGCAAGGCTTGAATCTTCTAGGTCTAGAAACATTAGAACGGATGTAA

Upstream 100 bases:

>100_bases
GAAAAAGTTCGCTAGAGGATAGTAATTCACCGCCACTAGCGGCTAAAATAGTCGGTTACCCCTTATTATTTCTCTTTATG
TAAGTGTCGATTAAACGCCA

Downstream 100 bases:

>100_bases
GCTTTAGCTCATGACAAATCGTGATTATGCAAACCGTAAGCCTGCTCGAAAAGGTAAGAACAGCGCTCGCAAAAAGAGCT
CAAAAGGGAGCGCTCCTAAG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MKSHTQSLLAESLNALKQQGIVPADFEARIQVDRTKDKSHGDFATNLAMMLTKAAGKNPRELAQLLIDNLPESSHVEKVE
IAGPGFINFFIDDNALANQLMAALNSDTLGIELPASQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFMGHKVIRQ
NHVGDWGTQFGMLLAYMEELRAANGEQAKMELSDLETFYRAAKVRFDESEEFATRARKLVVALQSGDEYCNKLWREFNDI
SLSHCHELYERLGVSLTRADVRGESAYNSDLAQVVADLDSQGLLSESNGAKVVFQDEFKNKEGEPLPVIIQKADGGYLYA
TSDLAAMRYRSNVLNADRALYFVDLRQALHFQQVFKLAKTAKFVREEMSFEHMGFGTMNGEDGRPFKTRSGGVVKLIDLL
KEADIRALDLVRSKNPDMDEAELAEIARVVGIASVKYADLSKNRASDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRA
QDVDLSDAKIILEHEKEKDLGTKLAQFGEVMARMVSKGQPHALCGYLFELAGAFSSFYEACPVLAAETEELKKSRLLLSQ
LTAKTLKQGLNLLGLETLERM

Sequences:

>Translated_581_residues
MKSHTQSLLAESLNALKQQGIVPADFEARIQVDRTKDKSHGDFATNLAMMLTKAAGKNPRELAQLLIDNLPESSHVEKVE
IAGPGFINFFIDDNALANQLMAALNSDTLGIELPASQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFMGHKVIRQ
NHVGDWGTQFGMLLAYMEELRAANGEQAKMELSDLETFYRAAKVRFDESEEFATRARKLVVALQSGDEYCNKLWREFNDI
SLSHCHELYERLGVSLTRADVRGESAYNSDLAQVVADLDSQGLLSESNGAKVVFQDEFKNKEGEPLPVIIQKADGGYLYA
TSDLAAMRYRSNVLNADRALYFVDLRQALHFQQVFKLAKTAKFVREEMSFEHMGFGTMNGEDGRPFKTRSGGVVKLIDLL
KEADIRALDLVRSKNPDMDEAELAEIARVVGIASVKYADLSKNRASDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRA
QDVDLSDAKIILEHEKEKDLGTKLAQFGEVMARMVSKGQPHALCGYLFELAGAFSSFYEACPVLAAETEELKKSRLLLSQ
LTAKTLKQGLNLLGLETLERM
>Mature_581_residues
MKSHTQSLLAESLNALKQQGIVPADFEARIQVDRTKDKSHGDFATNLAMMLTKAAGKNPRELAQLLIDNLPESSHVEKVE
IAGPGFINFFIDDNALANQLMAALNSDTLGIELPASQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFMGHKVIRQ
NHVGDWGTQFGMLLAYMEELRAANGEQAKMELSDLETFYRAAKVRFDESEEFATRARKLVVALQSGDEYCNKLWREFNDI
SLSHCHELYERLGVSLTRADVRGESAYNSDLAQVVADLDSQGLLSESNGAKVVFQDEFKNKEGEPLPVIIQKADGGYLYA
TSDLAAMRYRSNVLNADRALYFVDLRQALHFQQVFKLAKTAKFVREEMSFEHMGFGTMNGEDGRPFKTRSGGVVKLIDLL
KEADIRALDLVRSKNPDMDEAELAEIARVVGIASVKYADLSKNRASDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRA
QDVDLSDAKIILEHEKEKDLGTKLAQFGEVMARMVSKGQPHALCGYLFELAGAFSSFYEACPVLAAETEELKKSRLLLSQ
LTAKTLKQGLNLLGLETLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=573, Percent_Identity=39.9650959860384, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI197100773, Length=480, Percent_Identity=32.0833333333333, Blast_Score=197, Evalue=2e-50,
Organism=Escherichia coli, GI1788184, Length=580, Percent_Identity=54.6551724137931, Blast_Score=640, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=570, Percent_Identity=37.1929824561403, Blast_Score=349, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI71985068, Length=530, Percent_Identity=38.1132075471698, Blast_Score=338, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI17532153, Length=497, Percent_Identity=28.9738430583501, Blast_Score=158, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6320548, Length=569, Percent_Identity=31.9859402460457, Blast_Score=246, Evalue=7e-66,
Organism=Saccharomyces cerevisiae, GI6321883, Length=560, Percent_Identity=28.5714285714286, Blast_Score=216, Evalue=8e-57,
Organism=Drosophila melanogaster, GI18859963, Length=606, Percent_Identity=39.1089108910891, Blast_Score=390, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28571570, Length=486, Percent_Identity=34.7736625514403, Blast_Score=221, Evalue=1e-57,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64689; Mature: 64689

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHTQSLLAESLNALKQQGIVPADFEARIQVDRTKDKSHGDFATNLAMMLTKAAGKNPR
CCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHH
ELAQLLIDNLPESSHVEKVEIAGPGFINFFIDDNALANQLMAALNSDTLGIELPASQTVV
HHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCEEECCCCCEEE
VDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFMGHKVIRQNHVGDWGTQFGMLLAYMEEL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RAANGEQAKMELSDLETFYRAAKVRFDESEEFATRARKLVVALQSGDEYCNKLWREFNDI
HHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
SLSHCHELYERLGVSLTRADVRGESAYNSDLAQVVADLDSQGLLSESNGAKVVFQDEFKN
CHHHHHHHHHHHCCEEEEHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCC
KEGEPLPVIIQKADGGYLYATSDLAAMRYRSNVLNADRALYFVDLRQALHFQQVFKLAKT
CCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AKFVREEMSFEHMGFGTMNGEDGRPFKTRSGGVVKLIDLLKEADIRALDLVRSKNPDMDE
HHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCH
AELAEIARVVGIASVKYADLSKNRASDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRA
HHHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
QDVDLSDAKIILEHEKEKDLGTKLAQFGEVMARMVSKGQPHALCGYLFELAGAFSSFYEA
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
CPVLAAETEELKKSRLLLSQLTAKTLKQGLNLLGLETLERM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MKSHTQSLLAESLNALKQQGIVPADFEARIQVDRTKDKSHGDFATNLAMMLTKAAGKNPR
CCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHH
ELAQLLIDNLPESSHVEKVEIAGPGFINFFIDDNALANQLMAALNSDTLGIELPASQTVV
HHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCEEECCCCCEEE
VDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFMGHKVIRQNHVGDWGTQFGMLLAYMEEL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RAANGEQAKMELSDLETFYRAAKVRFDESEEFATRARKLVVALQSGDEYCNKLWREFNDI
HHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
SLSHCHELYERLGVSLTRADVRGESAYNSDLAQVVADLDSQGLLSESNGAKVVFQDEFKN
CHHHHHHHHHHHCCEEEEHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCC
KEGEPLPVIIQKADGGYLYATSDLAAMRYRSNVLNADRALYFVDLRQALHFQQVFKLAKT
CCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AKFVREEMSFEHMGFGTMNGEDGRPFKTRSGGVVKLIDLLKEADIRALDLVRSKNPDMDE
HHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCH
AELAEIARVVGIASVKYADLSKNRASDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRA
HHHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
QDVDLSDAKIILEHEKEKDLGTKLAQFGEVMARMVSKGQPHALCGYLFELAGAFSSFYEA
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
CPVLAAETEELKKSRLLLSQLTAKTLKQGLNLLGLETLERM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA