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The map label for this gene is macB [H]

Identifier: 157963177

GI number: 157963177

Start: 4105762

End: 4106973

Strand: Reverse

Name: macB [H]

Synonym: Spea_3362

Alternate gene names: 157963177

Gene position: 4106973-4105762 (Counterclockwise)

Preceding gene: 157963178

Following gene: 157963176

Centisome position: 79.37

GC content: 46.86

Gene sequence:

>1212_bases
ATGTTTCAAATTAAACCCATATTAAGCATGTTGATGCGTAATAAAAGCGGCCCTCTGTTGCTGCTTATTCAAATCATTTT
ATCGGTAGCGATTGTGGCAAATGCCAGTTTTATTATCACCGAGCGTGTCGGCCTGATGGCAAGAGAGTCTGGGATTGCAG
AGTCCGAAGTGTTTGATTTAACCATCTATAATTTCGATGACGCTATTGTCGCTAATGAGCAGAACCTGATTGATGTCGAG
ATAATACGTAACCTCGACGGTGTTAAGGCTGCCACCTCAACCAGTATGACTCCTTTGAGCGGTGGTGGTTGGTCATCGAA
CTTTTCCCATGGAAGCAGTGAAGAGGATCGTAAGGATACCCCCAGTTCGGCTATCTATTATGGTGATGAGAAGATGATCT
CAACTTTAGGTATTCAGCTAATTGAGGGGCGTAATTTTTATCCCGATGAAGTCAGCAGTGGTGGCCCTGAGCTCGCAACT
TTAGCCATAGTTTCAGCTGACTTTGCTAAAGACACTTTTGGTGATGAGTCAGCGGTTGGTCAAGTGATGTATCGGGGTAA
CATCGGTGATCAGCCGATGAAAATTATTGGCGTGGTGGAGCGTTTGCAAGGTGCATGGGTTGATCACGATAACTTAAACC
GTAGCGTGATCCTCAATGTGGAACTGGCATCCTCCTTTACGCGCTTTTTAGTGCGCGCCGATGAGTCTGCTATTGCAGAT
CTAAAAGAAGCGATTCCTGCGGCATTACATAAAGAGCACCCTAATCGCGTGGTTCGTGGCTTTAAAACCATTAGTGAACA
CCGCAATAACGTATATCGTAACCATGAGCTGATGGCGACCGTGTTGTCTATGATGGTGGTGCTACTACTGCTTATCACTT
CTTTAGGTCTTGCGGGCATGGTGATGTTTAACATCGAGCGCCGCACTAAACAGATAGGCACACGCCGAGCCCTTGGGGCA
AAGAAGCGCGACATTATCAGCTTCTTTCTGGTGGAGAATTATCTCTTGTGCCTCACTGGTGGGCTACTAGGAGGTTTGAT
TGCGGTGCTGCTCGGTCAGCAACTGATGTCGCTTTATAGTTTGCCTAAACTGGAGCTTGTCTATCCGATAGCCACGGTAG
CAGGCCTACTTGTGTTGACCACTATTGCAGTGATCTTACCTGCACAAAAAGCCGCTAAAATTTCACCCGCGATAGCGACT
CGCAGCGTGTAA

Upstream 100 bases:

>100_bases
CATTATTGCCGGGATCTACCCTGCATGGCGAATATGTAGCACCAACCCAAGTGTCTACCTCAAGAGTCAATAAACTACAG
AATGAGAAAGGACTTCATTT

Downstream 100 bases:

>100_bases
TCCACTACTGTTAACGCCAATAAATGCTATCTAATTGTTAGCCGAATGTGAGCTTTGCTTTAACTCTGTTCGGCTTTCAG
TTAGTTTGATAGCCAGCCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MFQIKPILSMLMRNKSGPLLLLIQIILSVAIVANASFIITERVGLMARESGIAESEVFDLTIYNFDDAIVANEQNLIDVE
IIRNLDGVKAATSTSMTPLSGGGWSSNFSHGSSEEDRKDTPSSAIYYGDEKMISTLGIQLIEGRNFYPDEVSSGGPELAT
LAIVSADFAKDTFGDESAVGQVMYRGNIGDQPMKIIGVVERLQGAWVDHDNLNRSVILNVELASSFTRFLVRADESAIAD
LKEAIPAALHKEHPNRVVRGFKTISEHRNNVYRNHELMATVLSMMVVLLLLITSLGLAGMVMFNIERRTKQIGTRRALGA
KKRDIISFFLVENYLLCLTGGLLGGLIAVLLGQQLMSLYSLPKLELVYPIATVAGLLVLTTIAVILPAQKAAKISPAIAT
RSV

Sequences:

>Translated_403_residues
MFQIKPILSMLMRNKSGPLLLLIQIILSVAIVANASFIITERVGLMARESGIAESEVFDLTIYNFDDAIVANEQNLIDVE
IIRNLDGVKAATSTSMTPLSGGGWSSNFSHGSSEEDRKDTPSSAIYYGDEKMISTLGIQLIEGRNFYPDEVSSGGPELAT
LAIVSADFAKDTFGDESAVGQVMYRGNIGDQPMKIIGVVERLQGAWVDHDNLNRSVILNVELASSFTRFLVRADESAIAD
LKEAIPAALHKEHPNRVVRGFKTISEHRNNVYRNHELMATVLSMMVVLLLLITSLGLAGMVMFNIERRTKQIGTRRALGA
KKRDIISFFLVENYLLCLTGGLLGGLIAVLLGQQLMSLYSLPKLELVYPIATVAGLLVLTTIAVILPAQKAAKISPAIAT
RSV
>Mature_403_residues
MFQIKPILSMLMRNKSGPLLLLIQIILSVAIVANASFIITERVGLMARESGIAESEVFDLTIYNFDDAIVANEQNLIDVE
IIRNLDGVKAATSTSMTPLSGGGWSSNFSHGSSEEDRKDTPSSAIYYGDEKMISTLGIQLIEGRNFYPDEVSSGGPELAT
LAIVSADFAKDTFGDESAVGQVMYRGNIGDQPMKIIGVVERLQGAWVDHDNLNRSVILNVELASSFTRFLVRADESAIAD
LKEAIPAALHKEHPNRVVRGFKTISEHRNNVYRNHELMATVLSMMVVLLLLITSLGLAGMVMFNIERRTKQIGTRRALGA
KKRDIISFFLVENYLLCLTGGLLGGLIAVLLGQQLMSLYSLPKLELVYPIATVAGLLVLTTIAVILPAQKAAKISPAIAT
RSV

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=279, Percent_Identity=25.089605734767, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43865; Mature: 43865

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQIKPILSMLMRNKSGPLLLLIQIILSVAIVANASFIITERVGLMARESGIAESEVFDL
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCEEEE
TIYNFDDAIVANEQNLIDVEIIRNLDGVKAATSTSMTPLSGGGWSSNFSHGSSEEDRKDT
EEEECCCCEEECCCCCEEHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PSSAIYYGDEKMISTLGIQLIEGRNFYPDEVSSGGPELATLAIVSADFAKDTFGDESAVG
CCCEEEECCHHHHHHHCHHEECCCCCCCCCCCCCCCCCEEEEEEEHHHHHCCCCCHHHHH
QVMYRGNIGDQPMKIIGVVERLQGAWVDHDNLNRSVILNVELASSFTRFLVRADESAIAD
HEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCHHHHHH
LKEAIPAALHKEHPNRVVRGFKTISEHRNNVYRNHELMATVLSMMVVLLLLITSLGLAGM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMFNIERRTKQIGTRRALGAKKRDIISFFLVENYLLCLTGGLLGGLIAVLLGQQLMSLYS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPKLELVYPIATVAGLLVLTTIAVILPAQKAAKISPAIATRSV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCC
>Mature Secondary Structure
MFQIKPILSMLMRNKSGPLLLLIQIILSVAIVANASFIITERVGLMARESGIAESEVFDL
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCEEEE
TIYNFDDAIVANEQNLIDVEIIRNLDGVKAATSTSMTPLSGGGWSSNFSHGSSEEDRKDT
EEEECCCCEEECCCCCEEHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PSSAIYYGDEKMISTLGIQLIEGRNFYPDEVSSGGPELATLAIVSADFAKDTFGDESAVG
CCCEEEECCHHHHHHHCHHEECCCCCCCCCCCCCCCCCEEEEEEEHHHHHCCCCCHHHHH
QVMYRGNIGDQPMKIIGVVERLQGAWVDHDNLNRSVILNVELASSFTRFLVRADESAIAD
HEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCHHHHHH
LKEAIPAALHKEHPNRVVRGFKTISEHRNNVYRNHELMATVLSMMVVLLLLITSLGLAGM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMFNIERRTKQIGTRRALGAKKRDIISFFLVENYLLCLTGGLLGGLIAVLLGQQLMSLYS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPKLELVYPIATVAGLLVLTTIAVILPAQKAAKISPAIATRSV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]