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The map label for this gene is luxS [H]

Identifier: 157962921

GI number: 157962921

Start: 3806980

End: 3807489

Strand: Reverse

Name: luxS [H]

Synonym: Spea_3104

Alternate gene names: 157962921

Gene position: 3807489-3806980 (Counterclockwise)

Preceding gene: 157962922

Following gene: 157962920

Centisome position: 73.58

GC content: 44.51

Gene sequence:

>510_bases
ATGCCGTTATTAGATAGTTTCACCGTTGACCACACACGAATGAATGCGCCAGCGGTTCGTGTTGCTAAATCCATGGCAAC
GCCTAAAGGCGACACCATAACGGTATTTGATCTGCGATTTTGCGTGCCTAATAAAGAGATCTTAAGCGAACGCGGCATTC
ATACCTTAGAGCATCTATTTGCTGGCTTTATGCGTGATCACTTAAATAGCGACAGCGTGGAGATCATCGATATTTCCCCA
ATGGGCTGTCGTACTGGTTTTTATATGAGTTTAATCGGTACGCCCTCAGAGTCGGTAGTCGCAGACGCTTGGCTTGCCGC
TATGCAAGATGTACTTAACGTTGTCGCCCAAGCTGATATTCCTGAACTCAATGAATATCAATGTGGCACTTATGAGATGC
ATTCTCTGGAGCAGGCGCAAGAGATTGCCCGTAATATTATTGCTGCAGGGATCAATGTTAACCGTAATGATGATTTAAGT
TTAAGTGACGAGATTTTGAAAGGGCTTTAG

Upstream 100 bases:

>100_bases
GGGTAAGTATCACCTAACCTCAGAGGATGCTTATAGTCGATTTAGGCAGTAATTAAACCTACGTTGATTAGCCACTTAAC
GCGAGTTTGGAGAAGTTGAT

Downstream 100 bases:

>100_bases
TCCGTCAGCTGTTAATCTCGTTTTAAGGCCGCTTTAGCGGCTTTTTTATTAGTATTTAATTCCTGTTTTGCTTATTTAAG
TAGATTTTTGCCCCTAAAAA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPLLDSFTVDHTRMNAPAVRVAKSMATPKGDTITVFDLRFCVPNKEILSERGIHTLEHLFAGFMRDHLNSDSVEIIDISP
MGCRTGFYMSLIGTPSESVVADAWLAAMQDVLNVVAQADIPELNEYQCGTYEMHSLEQAQEIARNIIAAGINVNRNDDLS
LSDEILKGL

Sequences:

>Translated_169_residues
MPLLDSFTVDHTRMNAPAVRVAKSMATPKGDTITVFDLRFCVPNKEILSERGIHTLEHLFAGFMRDHLNSDSVEIIDISP
MGCRTGFYMSLIGTPSESVVADAWLAAMQDVLNVVAQADIPELNEYQCGTYEMHSLEQAQEIARNIIAAGINVNRNDDLS
LSDEILKGL
>Mature_168_residues
PLLDSFTVDHTRMNAPAVRVAKSMATPKGDTITVFDLRFCVPNKEILSERGIHTLEHLFAGFMRDHLNSDSVEIIDISPM
GCRTGFYMSLIGTPSESVVADAWLAAMQDVLNVVAQADIPELNEYQCGTYEMHSLEQAQEIARNIIAAGINVNRNDDLSL
SDEILKGL

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=169, Percent_Identity=73.9644970414201, Blast_Score=270, Evalue=4e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 18653; Mature: 18522

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMNAPAVRVAKSMATPKGDTITVFDLRFCVPNKEILSERGIHTLEHLF
CCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHHHHH
AGFMRDHLNSDSVEIIDISPMGCRTGFYMSLIGTPSESVVADAWLAAMQDVLNVVAQADI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
PELNEYQCGTYEMHSLEQAQEIARNIIAAGINVNRNDDLSLSDEILKGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
PLLDSFTVDHTRMNAPAVRVAKSMATPKGDTITVFDLRFCVPNKEILSERGIHTLEHLF
CCCCCCCCCCHHCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHHHHH
AGFMRDHLNSDSVEIIDISPMGCRTGFYMSLIGTPSESVVADAWLAAMQDVLNVVAQADI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
PELNEYQCGTYEMHSLEQAQEIARNIIAAGINVNRNDDLSLSDEILKGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA