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The map label for this gene is yeiR [H]

Identifier: 157962819

GI number: 157962819

Start: 3677702

End: 3678838

Strand: Reverse

Name: yeiR [H]

Synonym: Spea_3001

Alternate gene names: 157962819

Gene position: 3678838-3677702 (Counterclockwise)

Preceding gene: 157962820

Following gene: 157962818

Centisome position: 71.09

GC content: 47.14

Gene sequence:

>1137_bases
ATGATCCAGAAAATAATCCCAACCAATGTGATTACCGGTTTTTTAGGTGTCGGCAAGACCTCGTTAATTAAGACTCTGCT
TAAACATAAGCCCGAGGGGGAGGTATGGGCGGTACTGGTCAATGAGTTTGGCGAAATAGGCATAGATGCTGGCTTACTCG
ATACTGGCAGTGAGCAGGTGCAGATCAAAGAGGTGGCAGGTGGCTGTATGTGCTGCGCGGCGGGCCTGCCCATGCAGGTC
GCTATCAACCAACTTATCGCGAAGGCGAAACCAGACAGATTATTGATTGAGCCGACGGGCCTTGGCCACCCTAAAGAGGT
ACTTAAGGTGCTGACTCAACCCCACTATCGGCAAGTGTTAGCGATGAAGGCTTGCGTGACCCTAGTGGATGCGAGAAAGC
TTAAGGATAGCCGCTACACCGAACATGAGATATTTAATCAACAGCTGCAAGTTGCCGATATTGTCTTGGCGAGTAAAGTC
GATAGTTATCCGGCCTCACTAATATCGGACTTGGCTGCATATCTAGATATGATTAATCCCTTAGCCCCTACACTTCAATC
TGCTGACAGTGACAGAGAAAGTGTGCCGATTATACCTTGGAGTTTAGAGCAGGCCGCAGAGCTTAGTGCTTCGATTATGT
CGTTGTTAGATAGACCGCATAGAGGCGCGACTTTAACAAATGCTAAAAATTTAGGCAGCAAGCCTAAAATATTAAGAAAA
AGCGAGGAGAGCATACAGGCGCCTCGTTTGGTCGATATTAACTATAGCCCGCTATTTTCAGAGCAAGCAGGCGGTCCATC
AACAGAGCAAAATATTGAATTTGATGAGCGTGGCCTGCTGCGTAAGAGCAATCAAGGCGATGGCTTTTACAGCTGTGGCT
GGGTATTTGACCCAAGCTATGAGTTCGACTTTGACAAACTACTAGTCTTAATAAAAAGTTTGCATGTACCTCGCCTTAAA
GCCGTGATGATCACCGAGGAGGGGATTGCAGGCTTTAACTGCGTAGAGTCTGAATTGTCCATCGTAGAGCTCGATGATGC
GATGGATTCACGTATCGAAATACTATCTATGTCTGAAATCGATATAGAGGGGCTTGAGGCGGCTTTGTTGGCTCTGTCTT
CACGTCTTGGGTTCTAG

Upstream 100 bases:

>100_bases
TTCAGCACCCAGCCTAATTAATCTAAAATACGCCTATGGCGTGACAGCTCTGCTTAATAGCGATTAGAATCTTAGGCAAT
TTGATAGATAGAGCTTAGCT

Downstream 100 bases:

>100_bases
CTATCTATTTTTAACTATCTATTAAAAAAATTACTTTTGCCATGCAGTATGTTAACTCGCGACTATTTTAAGTATTTTAT
AAGCGATTAAGCTGTAGAGC

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MIQKIIPTNVITGFLGVGKTSLIKTLLKHKPEGEVWAVLVNEFGEIGIDAGLLDTGSEQVQIKEVAGGCMCCAAGLPMQV
AINQLIAKAKPDRLLIEPTGLGHPKEVLKVLTQPHYRQVLAMKACVTLVDARKLKDSRYTEHEIFNQQLQVADIVLASKV
DSYPASLISDLAAYLDMINPLAPTLQSADSDRESVPIIPWSLEQAAELSASIMSLLDRPHRGATLTNAKNLGSKPKILRK
SEESIQAPRLVDINYSPLFSEQAGGPSTEQNIEFDERGLLRKSNQGDGFYSCGWVFDPSYEFDFDKLLVLIKSLHVPRLK
AVMITEEGIAGFNCVESELSIVELDDAMDSRIEILSMSEIDIEGLEAALLALSSRLGF

Sequences:

>Translated_378_residues
MIQKIIPTNVITGFLGVGKTSLIKTLLKHKPEGEVWAVLVNEFGEIGIDAGLLDTGSEQVQIKEVAGGCMCCAAGLPMQV
AINQLIAKAKPDRLLIEPTGLGHPKEVLKVLTQPHYRQVLAMKACVTLVDARKLKDSRYTEHEIFNQQLQVADIVLASKV
DSYPASLISDLAAYLDMINPLAPTLQSADSDRESVPIIPWSLEQAAELSASIMSLLDRPHRGATLTNAKNLGSKPKILRK
SEESIQAPRLVDINYSPLFSEQAGGPSTEQNIEFDERGLLRKSNQGDGFYSCGWVFDPSYEFDFDKLLVLIKSLHVPRLK
AVMITEEGIAGFNCVESELSIVELDDAMDSRIEILSMSEIDIEGLEAALLALSSRLGF
>Mature_378_residues
MIQKIIPTNVITGFLGVGKTSLIKTLLKHKPEGEVWAVLVNEFGEIGIDAGLLDTGSEQVQIKEVAGGCMCCAAGLPMQV
AINQLIAKAKPDRLLIEPTGLGHPKEVLKVLTQPHYRQVLAMKACVTLVDARKLKDSRYTEHEIFNQQLQVADIVLASKV
DSYPASLISDLAAYLDMINPLAPTLQSADSDRESVPIIPWSLEQAAELSASIMSLLDRPHRGATLTNAKNLGSKPKILRK
SEESIQAPRLVDINYSPLFSEQAGGPSTEQNIEFDERGLLRKSNQGDGFYSCGWVFDPSYEFDFDKLLVLIKSLHVPRLK
AVMITEEGIAGFNCVESELSIVELDDAMDSRIEILSMSEIDIEGLEAALLALSSRLGF

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=200, Percent_Identity=30, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI223941779, Length=200, Percent_Identity=30, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI33469141, Length=199, Percent_Identity=30.1507537688442, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI146231952, Length=200, Percent_Identity=30.5, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI148727351, Length=200, Percent_Identity=30, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1788499, Length=367, Percent_Identity=37.0572207084469, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI87082430, Length=192, Percent_Identity=30.7291666666667, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 41344; Mature: 41344

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQKIIPTNVITGFLGVGKTSLIKTLLKHKPEGEVWAVLVNEFGEIGIDAGLLDTGSEQV
CCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCE
QIKEVAGGCMCCAAGLPMQVAINQLIAKAKPDRLLIEPTGLGHPKEVLKVLTQPHYRQVL
EEHHHCCCCEEHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHH
AMKACVTLVDARKLKDSRYTEHEIFNQQLQVADIVLASKVDSYPASLISDLAAYLDMINP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LAPTLQSADSDRESVPIIPWSLEQAAELSASIMSLLDRPHRGATLTNAKNLGSKPKILRK
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCHHHCCCCCHHHHC
SEESIQAPRLVDINYSPLFSEQAGGPSTEQNIEFDERGLLRKSNQGDGFYSCGWVFDPSY
CHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEECEEECCCC
EFDFDKLLVLIKSLHVPRLKAVMITEEGIAGFNCVESELSIVELDDAMDSRIEILSMSEI
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHCCCCEEEECHHHCCCEEEEEECCC
DIEGLEAALLALSSRLGF
CHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIQKIIPTNVITGFLGVGKTSLIKTLLKHKPEGEVWAVLVNEFGEIGIDAGLLDTGSEQV
CCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCE
QIKEVAGGCMCCAAGLPMQVAINQLIAKAKPDRLLIEPTGLGHPKEVLKVLTQPHYRQVL
EEHHHCCCCEEHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHH
AMKACVTLVDARKLKDSRYTEHEIFNQQLQVADIVLASKVDSYPASLISDLAAYLDMINP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LAPTLQSADSDRESVPIIPWSLEQAAELSASIMSLLDRPHRGATLTNAKNLGSKPKILRK
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCHHHCCCCCHHHHC
SEESIQAPRLVDINYSPLFSEQAGGPSTEQNIEFDERGLLRKSNQGDGFYSCGWVFDPSY
CHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEECEEECCCC
EFDFDKLLVLIKSLHVPRLKAVMITEEGIAGFNCVESELSIVELDDAMDSRIEILSMSEI
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHCCCCEEEECHHHCCCEEEEEECCC
DIEGLEAALLALSSRLGF
CHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]