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The map label for this gene is rlmM [H]

Identifier: 157962799

GI number: 157962799

Start: 3653750

End: 3654832

Strand: Reverse

Name: rlmM [H]

Synonym: Spea_2981

Alternate gene names: 157962799

Gene position: 3654832-3653750 (Counterclockwise)

Preceding gene: 157962800

Following gene: 157962797

Centisome position: 70.63

GC content: 44.04

Gene sequence:

>1083_bases
ATGATAAACCTATTTTTATTTTGCCGTGCTGGCTATGAGAAAGATTGCGCAGCAGAGATCCAAGTGCGCGCAGCTGAGCT
CGATATTGGTGGATTTGTAAAAACCAATACTAATGATGCTTATGTGATTTTTCAGTGCTTCCAAGCCGGTGATGCTGAAG
TTTTAGCTAAAAATATCAGTCTAGACTCGCTTATTTTTGCCAGACAGATGTTTGCAGCAAAAGAGTTGCTAAAAGGTTTA
CCTGAGCAAGATAGAATTAGTCCGATTGTTGAAGCCTTAACTCAGGTGAACAAAGCGGGTGAACTGCGCGTTGAGACGCC
AGATACCAACGAAGCGAAAGAACGTTCAAACTTCTGCCGTAAGTTTACTGTACCGCTTAGACAAGCGTTAAAGAAATCTG
GCGCCTTGCTTGAGAAAGAAAACCCTAAGCGACCTATTATTCATGTGTGTTTTGTTGCCTCTGGCCAAGCATATGTCGGT
TACTCTTTAAGTAACAATAGCTCACCTTATTTCATGGGGATCCCAAGACTTAAGATTGCTGCTGATGCACCGAGTCGCTC
TACTCTTAAGTTAGATGAAGCTTTTATTCACTTCATTCCTAAAGAAGAGCAAGAAACGCGTCTAAGCAGTGGTATGAAGG
CTGTGGATCTTGGTGCTTGTCCTGGTGGTTGGACTTATCAACTTGTGAGACGCGGTATGTTTGTTGCGGCTGTCGATAAC
GGCCCGATGGATCAAGGCTTGATGGATACCGGGCAGGTAAAACATTACCAAGCTGACGGATTTAGATTCGAGCCACCAAG
AAAGAACATCACTTGGTTAGTTTGCGACATGATTGAAAAGCCATCTCGCGTGGCAGAGCTGATCGAAGCCTGGGCAATCA
ATGGCTGGTTTAAAGAGTCAATCTTCAACTTAAAACTGCCTATGAAGGCGCGTTATAAAGAAGTGTCGACCATTCTAGCT
ACGATGGAAGAGATTTTAAAAGAGAACGGTGTAGATGACTTCTCTATCGCGGCGAAACATTTATATCACGACCGTGACGA
AGTGACCGTTCACCTCTGCTTGCGACCAAGTCAACCTTGGTAA

Upstream 100 bases:

>100_bases
CAATAATGCTAGTGGATTTAAGCACTATGATTTTGGAGTGACAGTGCCATTTTTAATCATGGTGCTTTGATTGATATTAT
TTTTATCTTCAGGAAATTCA

Downstream 100 bases:

>100_bases
ATATTGACGAAAGTGTCGGCTTATCTCAGGACGGCACTGAGCATTAAAAAAGGCCCCATGTGCAAACATGGGGCCTTTTT
AGTCACTCAACAGAATTAAG

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNISLDSLIFARQMFAAKELLKGL
PEQDRISPIVEALTQVNKAGELRVETPDTNEAKERSNFCRKFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVG
YSLSNNSSPYFMGIPRLKIAADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKESIFNLKLPMKARYKEVSTILA
TMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW

Sequences:

>Translated_360_residues
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNISLDSLIFARQMFAAKELLKGL
PEQDRISPIVEALTQVNKAGELRVETPDTNEAKERSNFCRKFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVG
YSLSNNSSPYFMGIPRLKIAADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKESIFNLKLPMKARYKEVSTILA
TMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW
>Mature_360_residues
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNISLDSLIFARQMFAAKELLKGL
PEQDRISPIVEALTQVNKAGELRVETPDTNEAKERSNFCRKFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVG
YSLSNNSSPYFMGIPRLKIAADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKESIFNLKLPMKARYKEVSTILA
TMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=353, Percent_Identity=58.9235127478753, Blast_Score=436, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 40476; Mature: 40476

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNIS
CEEEEEEEECCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEEEEECCCCHHHHHHCCC
LDSLIFARQMFAAKELLKGLPEQDRISPIVEALTQVNKAGELRVETPDTNEAKERSNFCR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVGYSLSNNSSPYFMGIPRLKIA
HHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEECCCEEEEEEECCCCCCEEEECCCEEEE
ADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
ECCCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHCCEEEEEECC
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKES
CCCCCCCCCCCCEEEEECCCEEECCCCCCCEEEEEEHHHCCHHHHHHHHHHHCCCHHHHH
IFNLKLPMKARYKEVSTILATMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW
HHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNIS
CEEEEEEEECCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEEEEECCCCHHHHHHCCC
LDSLIFARQMFAAKELLKGLPEQDRISPIVEALTQVNKAGELRVETPDTNEAKERSNFCR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVGYSLSNNSSPYFMGIPRLKIA
HHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEECCCEEEEEEECCCCCCEEEECCCEEEE
ADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
ECCCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHCCEEEEEECC
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKES
CCCCCCCCCCCCEEEEECCCEEECCCCCCCEEEEEEHHHCCHHHHHHHHHHHCCCHHHHH
IFNLKLPMKARYKEVSTILATMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW
HHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA