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The map label for this gene is ribE [H]

Identifier: 157962088

GI number: 157962088

Start: 2744451

End: 2745068

Strand: Reverse

Name: ribE [H]

Synonym: Spea_2267

Alternate gene names: 157962088

Gene position: 2745068-2744451 (Counterclockwise)

Preceding gene: 157962092

Following gene: 157962084

Centisome position: 53.05

GC content: 42.23

Gene sequence:

>618_bases
ATGTTTACAGGTATAGTTCAAGCAACATGCGAAGTGTTGGCGATAGATAAGAAATCAGGCTTAAACACGCTACAAATCGC
AATTGGGCCGGATTTGCGCGAGGGACTTTCACTAGGGGCAAGTGTCGCAAATAACGGTGTATGTTTAACAGTCACAAGAA
TAGAAGATGATAGGGTGTTTTTCGATGTAATGGAAGAGACCCTTAAGCTAACTAACCTATCAAAACTGAGAGTTGGCTCA
CAGGTTAACATCGAGCGTTCATTAACATTCGGAAGTGAGATAGGTGGCCACATTTTATCGGGGCATGTTCACACTCAAGC
CGAGGTAGATTTGGTGAGCGCTACTGATGAACATTACGACATTCGTTTGAAGGTTGAGCCTAAATGGATGAATTACATTT
TGTATAAAGGCTTTGTTGGTGTAAACGGCTGTAGTCTGACGGTAGGAGAGGTGACAGCAGACACCTTTATGCTGCATTTA
ATTCCTGAAACGTTGAAACTAACCAATTTAGACAGCTATGTTAAGGGCGATAACATTAACATTGAGATAGACAGTCAGAC
TCAAGCCATCGTCGATACGGTAGAGCGTGTACTTGCCAAACGTTTCGACAATAACTAA

Upstream 100 bases:

>100_bases
TTGGGCAATAAGCACTGGTAGCGCTAATTGGACTAAGCGTTTGGCTTGAAAGCCAGAATGGTTCATGGGTACAGCCCTTA
ATATACTAACGAGAGATAAG

Downstream 100 bases:

>100_bases
TACTTGCTTTCGCAACAAATTGATGGGCAGATCTGTGGCTTAGTAGATCTGCTCATCGTCTGAATCAATGAAAAACTCGA
TTTTGTGCTTGGCTTCATCC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MFTGIVQATCEVLAIDKKSGLNTLQIAIGPDLREGLSLGASVANNGVCLTVTRIEDDRVFFDVMEETLKLTNLSKLRVGS
QVNIERSLTFGSEIGGHILSGHVHTQAEVDLVSATDEHYDIRLKVEPKWMNYILYKGFVGVNGCSLTVGEVTADTFMLHL
IPETLKLTNLDSYVKGDNINIEIDSQTQAIVDTVERVLAKRFDNN

Sequences:

>Translated_205_residues
MFTGIVQATCEVLAIDKKSGLNTLQIAIGPDLREGLSLGASVANNGVCLTVTRIEDDRVFFDVMEETLKLTNLSKLRVGS
QVNIERSLTFGSEIGGHILSGHVHTQAEVDLVSATDEHYDIRLKVEPKWMNYILYKGFVGVNGCSLTVGEVTADTFMLHL
IPETLKLTNLDSYVKGDNINIEIDSQTQAIVDTVERVLAKRFDNN
>Mature_205_residues
MFTGIVQATCEVLAIDKKSGLNTLQIAIGPDLREGLSLGASVANNGVCLTVTRIEDDRVFFDVMEETLKLTNLSKLRVGS
QVNIERSLTFGSEIGGHILSGHVHTQAEVDLVSATDEHYDIRLKVEPKWMNYILYKGFVGVNGCSLTVGEVTADTFMLHL
IPETLKLTNLDSYVKGDNINIEIDSQTQAIVDTVERVLAKRFDNN

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=202, Percent_Identity=53.4653465346535, Blast_Score=211, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6319733, Length=197, Percent_Identity=34.010152284264, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22556; Mature: 22556

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVQATCEVLAIDKKSGLNTLQIAIGPDLREGLSLGASVANNGVCLTVTRIEDDRVF
CCCCHHHHEEEEEEEECCCCCCEEEEEECCCHHHHHHCCHHHCCCCEEEEEEEECCCHHH
FDVMEETLKLTNLSKLRVGSQVNIERSLTFGSEIGGHILSGHVHTQAEVDLVSATDEHYD
HHHHHHHHHHCCCHHHCCCCEECEEEEEECCCCCCCEEEECEEECCEEEEEEECCCCCEE
IRLKVEPKWMNYILYKGFVGVNGCSLTVGEVTADTFMLHLIPETLKLTNLDSYVKGDNIN
EEEEECCHHHEEEEEECCCCCCCCEEEECCHHHHHEEEEECCCHHEECCCCHHCCCCCEE
IEIDSQTQAIVDTVERVLAKRFDNN
EEECCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIVQATCEVLAIDKKSGLNTLQIAIGPDLREGLSLGASVANNGVCLTVTRIEDDRVF
CCCCHHHHEEEEEEEECCCCCCEEEEEECCCHHHHHHCCHHHCCCCEEEEEEEECCCHHH
FDVMEETLKLTNLSKLRVGSQVNIERSLTFGSEIGGHILSGHVHTQAEVDLVSATDEHYD
HHHHHHHHHHCCCHHHCCCCEECEEEEEECCCCCCCEEEECEEECCEEEEEEECCCCCEE
IRLKVEPKWMNYILYKGFVGVNGCSLTVGEVTADTFMLHLIPETLKLTNLDSYVKGDNIN
EEEEECCHHHEEEEEECCCCCCCCEEEECCHHHHHEEEEECCCHHEECCCCHHCCCCCEE
IEIDSQTQAIVDTVERVLAKRFDNN
EEECCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9022701; 9023191; 9097039; 9278503; 11377200 [H]