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The map label for this gene is infC [H]

Identifier: 157962083

GI number: 157962083

Start: 2740313

End: 2740789

Strand: Reverse

Name: infC [H]

Synonym: Spea_2262

Alternate gene names: 157962083

Gene position: 2740789-2740313 (Counterclockwise)

Preceding gene: 157962084

Following gene: 157962082

Centisome position: 52.97

GC content: 43.61

Gene sequence:

>477_bases
GTGCCAGAAGTCCGTCTAAACGGTCTTGATGGTGAGCAGTTAGGCATCTTAACTATTAAAGAAGCACAAGAAGTTGCTGA
TGAAGCCGGTGTTGATTTAGTAGAAATCAGTCCTAACGCTGAGCCGCCAGTTTGTCGTGTTATGGACTACGGTAAGTTCC
TTTTTGACAAAGCAAAAGCTCAAAAAGAACAAAAGAAGAAGCAGAAAATTGTACAGGTGAAGGAAATTAAATTCCGTCCC
GGTACAGACGAAAACGATTACCAGGTAAAACTACGCAACCTGACTCGTTTTCTAGAAGACGGCGACAAAGCGAAAGTAAC
GCTGCGTTTCCGTGGTCGTGAGATGGCTCACCAAAGTTTAGGTATGGATCTTTTGAACCGTATCAAAGCTGATTTGGAAG
TTATTGCAGTCGTGGAGTCTTTCCCGAAAATGGAAGGTCGCCAAGCTGTAATGGTTCTTGCGCCGAAAAAGAAATAG

Upstream 100 bases:

>100_bases
GCTCCGTAGTCTCAATTTGTTGGAGGATTAGGTCATAAAGATCAAGAAAACAGCAGGGCGCCAGGCGGCCCCAAACAGAA
TTAACGAACTCATCACTGGC

Downstream 100 bases:

>100_bases
TAAGGCAACCATAAAAGTAGCAGGGGCCTGTTAAGGTTTCCTGTTCGCCTTGCGTTTTATTAATTGTCCCAATGCGGAGT
TTTAGCAATGCCTAAAATGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MPEVRLNGLDGEQLGILTIKEAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKAQKEQKKKQKIVQVKEIKFRP
GTDENDYQVKLRNLTRFLEDGDKAKVTLRFRGREMAHQSLGMDLLNRIKADLEVIAVVESFPKMEGRQAVMVLAPKKK

Sequences:

>Translated_158_residues
MPEVRLNGLDGEQLGILTIKEAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKAQKEQKKKQKIVQVKEIKFRP
GTDENDYQVKLRNLTRFLEDGDKAKVTLRFRGREMAHQSLGMDLLNRIKADLEVIAVVESFPKMEGRQAVMVLAPKKK
>Mature_157_residues
PEVRLNGLDGEQLGILTIKEAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKAQKEQKKKQKIVQVKEIKFRPG
TDENDYQVKLRNLTRFLEDGDKAKVTLRFRGREMAHQSLGMDLLNRIKADLEVIAVVESFPKMEGRQAVMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=157, Percent_Identity=77.7070063694268, Blast_Score=234, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17924; Mature: 17793

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEVRLNGLDGEQLGILTIKEAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKA
CCCCEECCCCCCCEEEEEHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
QKEQKKKQKIVQVKEIKFRPGTDENDYQVKLRNLTRFLEDGDKAKVTLRFRGREMAHQSL
HHHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHHHHHHCCCCEEEEEEECCHHHHHHHC
GMDLLNRIKADLEVIAVVESFPKMEGRQAVMVLAPKKK
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
PEVRLNGLDGEQLGILTIKEAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKA
CCCEECCCCCCCEEEEEHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
QKEQKKKQKIVQVKEIKFRPGTDENDYQVKLRNLTRFLEDGDKAKVTLRFRGREMAHQSL
HHHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHHHHHHCCCCEEEEEEECCHHHHHHHC
GMDLLNRIKADLEVIAVVESFPKMEGRQAVMVLAPKKK
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA