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The map label for this gene is fadH [H]

Identifier: 157962073

GI number: 157962073

Start: 2730078

End: 2732093

Strand: Reverse

Name: fadH [H]

Synonym: Spea_2252

Alternate gene names: 157962073

Gene position: 2732093-2730078 (Counterclockwise)

Preceding gene: 157962076

Following gene: 157962072

Centisome position: 52.8

GC content: 46.38

Gene sequence:

>2016_bases
ATGTCGTTTCCGCATTTATTAGAACCCTTAGATCTGGGATTTACCCAGTTAAAAAACCGAGTATTGATGGGCTCAATGCA
TACAGGTTTGGAAGAAGAAAAGGGCGGCTTTGAGAAACTGGCAGCGTTTTATAAAGAGCGCGCATTAGGTGGCGTAGGTC
TTATTGTGACAGGTGGCATATCGCCAAACCTACGGGGGCGTTTAGCACCTAATGCCTGCCAACTTAGTTTTCCGTGGCAG
GTTAAGAAACATACCAAAGTGACTCAAGCCGTGCATGAGGCTGGCGGCAAAATTTGTATGCAACTCTTGCATGCCGGTCG
CTACGGCTACCATCCTTTCTCTAGTGCACCGAGTAAGATTAAATCGCCTATTACCCCATTTACACCATCGGCTATGTCTG
CAAGACAGGTTAACGGGACAATCAAAGATTATGCCACCAGCGCAGCTCTAGCAAAAAAGGCGGGTTATGATGGTGTAGAG
GTGATGGGAAGCGAAGGTTACTTGATAAACCAGTTTATCAGCTCTCGTACTAATAAACGTACCGATAAGTGGGGCGGGGC
TTTTGAAAATCGTGCCCAATTCCCGATCGAAATTGTTAAAAAAATTCGAGAAAAAGTCGGCTCTGACTTTATCATTATTT
TTAGATTATCTATGTTAGATCTTGTCGATAACGGTTCGACTTGGGAAGAGGTGGTGCAGCTGGCTAAATGGCTAGAACAA
GCTGGCGTGACCATTATCAACACAGGTATTGGTTGGCATGAGGCTCGTGTACCGACCATTGCCACGAGCGTACCGCGCGG
CGCCTTTGCTTGGGTGACTGAGCGTTTGATGAAAGAGATGTCAATTCCGCTTATTGCCACTAACCGAATTAACACACCTG
AAATAGCCGAGCACATTATCTCATCGGGTCAGGCCGACATGGTGTCGATGGCGAGGCCTTTCCTTGCTGATGCCGAGTTT
GTCAATAAAGCAGCTGCCAATACACCTGAACTGATTAATACCTGTATTGGTTGTAACCAAGCCTGCTTGGACCATAGTTT
TGCCCTTAAACGTGCAACTTGTCTTGTTAACCCTAGAGCTTGTTATGAAACCGAGCTTAACTTCACGCCGGTACAAAAGA
AGAAGCGTATTGCGGTTATGGGCGCTGGTCCAGCCGGTATGGCATTTTCTATTTATGCGGCGAGTCGTGGCCATGAAGTG
GTGTTATTTGAAGCGAAAGCTGAAGTTGGTGGTCAGTTTAACCTAGCTCGTAAGATCCCGGGGAAAGAAGAGTTTAACGA
AACAATTCGATACTTCCTTAATCAGATTAAGCTACATAAGGTGGAACTTCGCTTAAACACTCGTCTCGATGCCAGTGTGG
TACGTGATGAGAAGTTTGATGAAATCGTTATGTCTAGTGGTGTAAAACCAAGACCTATTGAGTTACCTGGTTTCGATAAC
CCTAAGGTGGTTGATTACCAGAAGGTGCTCAATGGCGAAGTCGAAATTGGTCAGAAGGTCGCGTTAATCGGTGCGGGAGG
CATAGGTTTTGATATGGCTCACTTCCTGTGTGAGTCTGAGTCTTCAACACTGGATCTTAATCGCTGGTTAAAGCAGTGGG
GGATAGATAAAGACTATAAAGAGCCTGGTGGACTCACAGTCCCAGTTACTGAAGATAAACACAGACAAGTGTATCTGCTA
CAGCGTAAATCGACCAAGATGGGCAAGGGGCTTGGCAAAACCACCGGTTGGATCCATCGATCGGTGCTGAAGCAGCATCA
TGTAATAATGAAAACAGGCGTTAGCTACGAGAAATTCGACCAGCTAGGCCTACACATTAGCATCGATGGTAAAAGCGAGG
TATTGGATGTCGATAATGTCATCTTATGTGCTGGGCAAGTATCAAATACCGAACTTGTTGATGAGATGAAGTCTACAGGC
ATTCCAGTTCACCTTATTGGCGGTGTCGATGTGGCTGCCGAACTCGATGCCAAGCGCGCTATTCGTCAAGGTGCGGAGCT
TGCTATCGCGCTGTAA

Upstream 100 bases:

>100_bases
GGAAAACTCAATTGTAAAGGAATCTATTCATACACTTATTGAGGTTATTGTTTACACAGGGTATGCTGGATTAAATCACT
TGTTTAAAAAGGATGTTTGA

Downstream 100 bases:

>100_bases
GAGTAAGGTAAAACCGTAAATATGAAACCTGCCGCAGTAAATAACTGGGCAGGTTTTTTTATTGGGTATTACTGTCGCAG
TGTTGTTCCTGTTCGAATCG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLAPNACQLSFPWQ
VKKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKIKSPITPFTPSAMSARQVNGTIKDYATSAALAKKAGYDGVE
VMGSEGYLINQFISSRTNKRTDKWGGAFENRAQFPIEIVKKIREKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQ
AGVTIINTGIGWHEARVPTIATSVPRGAFAWVTERLMKEMSIPLIATNRINTPEIAEHIISSGQADMVSMARPFLADAEF
VNKAAANTPELINTCIGCNQACLDHSFALKRATCLVNPRACYETELNFTPVQKKKRIAVMGAGPAGMAFSIYAASRGHEV
VLFEAKAEVGGQFNLARKIPGKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVMSSGVKPRPIELPGFDN
PKVVDYQKVLNGEVEIGQKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYKEPGGLTVPVTEDKHRQVYLL
QRKSTKMGKGLGKTTGWIHRSVLKQHHVIMKTGVSYEKFDQLGLHISIDGKSEVLDVDNVILCAGQVSNTELVDEMKSTG
IPVHLIGGVDVAAELDAKRAIRQGAELAIAL

Sequences:

>Translated_671_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLAPNACQLSFPWQ
VKKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKIKSPITPFTPSAMSARQVNGTIKDYATSAALAKKAGYDGVE
VMGSEGYLINQFISSRTNKRTDKWGGAFENRAQFPIEIVKKIREKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQ
AGVTIINTGIGWHEARVPTIATSVPRGAFAWVTERLMKEMSIPLIATNRINTPEIAEHIISSGQADMVSMARPFLADAEF
VNKAAANTPELINTCIGCNQACLDHSFALKRATCLVNPRACYETELNFTPVQKKKRIAVMGAGPAGMAFSIYAASRGHEV
VLFEAKAEVGGQFNLARKIPGKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVMSSGVKPRPIELPGFDN
PKVVDYQKVLNGEVEIGQKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYKEPGGLTVPVTEDKHRQVYLL
QRKSTKMGKGLGKTTGWIHRSVLKQHHVIMKTGVSYEKFDQLGLHISIDGKSEVLDVDNVILCAGQVSNTELVDEMKSTG
IPVHLIGGVDVAAELDAKRAIRQGAELAIAL
>Mature_670_residues
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLAPNACQLSFPWQV
KKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKIKSPITPFTPSAMSARQVNGTIKDYATSAALAKKAGYDGVEV
MGSEGYLINQFISSRTNKRTDKWGGAFENRAQFPIEIVKKIREKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQA
GVTIINTGIGWHEARVPTIATSVPRGAFAWVTERLMKEMSIPLIATNRINTPEIAEHIISSGQADMVSMARPFLADAEFV
NKAAANTPELINTCIGCNQACLDHSFALKRATCLVNPRACYETELNFTPVQKKKRIAVMGAGPAGMAFSIYAASRGHEVV
LFEAKAEVGGQFNLARKIPGKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVMSSGVKPRPIELPGFDNP
KVVDYQKVLNGEVEIGQKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYKEPGGLTVPVTEDKHRQVYLLQ
RKSTKMGKGLGKTTGWIHRSVLKQHHVIMKTGVSYEKFDQLGLHISIDGKSEVLDVDNVILCAGQVSNTELVDEMKSTGI
PVHLIGGVDVAAELDAKRAIRQGAELAIAL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=677, Percent_Identity=54.9483013293944, Blast_Score=776, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=349, Percent_Identity=28.6532951289398, Blast_Score=111, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17540738, Length=235, Percent_Identity=29.3617021276596, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=347, Percent_Identity=23.9193083573487, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565138, Length=230, Percent_Identity=25.2173913043478, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17559804, Length=250, Percent_Identity=26.8, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=175, Percent_Identity=30.2857142857143, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72001454, Length=182, Percent_Identity=30.2197802197802, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=256, Percent_Identity=25.78125, Blast_Score=83, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=30.3418803418803, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=232, Percent_Identity=26.7241379310345, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73753; Mature: 73622

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGI
CCCCCCCCHHHCCHHHHHCHHEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLAPNACQLSFPWQVKKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKI
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
KSPITPFTPSAMSARQVNGTIKDYATSAALAKKAGYDGVEVMGSEGYLINQFISSRTNKR
CCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
TDKWGGAFENRAQFPIEIVKKIREKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQ
CHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHH
AGVTIINTGIGWHEARVPTIATSVPRGAFAWVTERLMKEMSIPLIATNRINTPEIAEHII
CCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
SSGQADMVSMARPFLADAEFVNKAAANTPELINTCIGCNQACLDHSFALKRATCLVNPRA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCH
CYETELNFTPVQKKKRIAVMGAGPAGMAFSIYAASRGHEVVLFEAKAEVGGQFNLARKIP
HEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEHHCCC
GKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVMSSGVKPRPIELPGFDN
CHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHCCHHHHHHHHCCCCCCCEECCCCCC
PKVVDYQKVLNGEVEIGQKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYK
CCEEEHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCC
EPGGLTVPVTEDKHRQVYLLQRKSTKMGKGLGKTTGWIHRSVLKQHHVIMKTGVSYEKFD
CCCCEEEEECCCCCCEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
QLGLHISIDGKSEVLDVDNVILCAGQVSNTELVDEMKSTGIPVHLIGGVDVAAELDAKRA
HCCCEEEECCCCCEEECCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
IRQGAELAIAL
HHCCCCEEEEC
>Mature Secondary Structure 
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGI
CCCCCCCHHHCCHHHHHCHHEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLAPNACQLSFPWQVKKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKI
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
KSPITPFTPSAMSARQVNGTIKDYATSAALAKKAGYDGVEVMGSEGYLINQFISSRTNKR
CCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
TDKWGGAFENRAQFPIEIVKKIREKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQ
CHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHH
AGVTIINTGIGWHEARVPTIATSVPRGAFAWVTERLMKEMSIPLIATNRINTPEIAEHII
CCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
SSGQADMVSMARPFLADAEFVNKAAANTPELINTCIGCNQACLDHSFALKRATCLVNPRA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCH
CYETELNFTPVQKKKRIAVMGAGPAGMAFSIYAASRGHEVVLFEAKAEVGGQFNLARKIP
HEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEHHCCC
GKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVMSSGVKPRPIELPGFDN
CHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHCCHHHHHHHHCCCCCCCEECCCCCC
PKVVDYQKVLNGEVEIGQKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYK
CCEEEHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCC
EPGGLTVPVTEDKHRQVYLLQRKSTKMGKGLGKTTGWIHRSVLKQHHVIMKTGVSYEKFD
CCCCEEEEECCCCCCEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
QLGLHISIDGKSEVLDVDNVILCAGQVSNTELVDEMKSTGIPVHLIGGVDVAAELDAKRA
HCCCEEEECCCCCEEECCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
IRQGAELAIAL
HHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]