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The map label for this gene is yngJ [H]

Identifier: 157961981

GI number: 157961981

Start: 2614177

End: 2615253

Strand: Direct

Name: yngJ [H]

Synonym: Spea_2160

Alternate gene names: 157961981

Gene position: 2614177-2615253 (Clockwise)

Preceding gene: 157961980

Following gene: 157961982

Centisome position: 50.52

GC content: 46.7

Gene sequence:

>1077_bases
ATGGACTTTACATTCACAGAAGATGAACTCGCATTTCGAGAAGCCATCAGTCGATTTTTAATGACCGAAGCGGCTCCTGA
GGCGTTGAGAGAGATTTGGGAGACTGATACGGGACGCTCACCTGAATTGCGCAATAAAATTGCCGAGCAAGGCTTAACGG
CACTATCTATTCCAGAAGAAGATGGCGGCTTAGGACTTGGTGACGTTGCTTGGTCTTTAATGACCCAAGAGCTGGGTTAT
TACGGGATCCCCGATAGCTTAGCTGATACTGCATATCTTGCTGCAGGCGTGCTAACAGCGCGGCCGCAAACTGACAATCT
AGAACGCAATCAACAGATTAAGCAATGGTTAACTGCAATCGGCGAAGGCAGTATTCGTGTTGCTGTCGGCCATCCAGTTA
ATCCGCTAGTGGCTGACGCTGCAGTAGCTGATCTGTTAATCCTGCTCGATGGTGATGATGTACATGCCGTTACACGTAAA
GATATTGATGTAGTGCTGCGCCCAAGTATCGATTCATCAAGACGGCTTGCTAAAGTCAGTTGGCAACCAAGTCGCGATAG
CTTGCTTGCTTCAGGTGAAGTAGGCAAAGCGATTCAACAGCAAATATTAAACCGCGGCGCTTTGTCAGCGGCTGGGCAGT
TGTTAGGTTTAGCGCAAAGAATGCTAGATCTGTCTATTGATTATGTTGCACAGCGTAAGCAATTTGGCCGTGTAATCGGT
AGTTTTCAAGCCGTTAAACACCACTTGGCAGATGTGGCATCAAAAATAGAGATGGCAAAACCCGTGCTATACCGCGCTGC
AAAGGAGTTTGATGACGAAAGTGTCGACTCTTCTGTGTATATTTCTCAAGCCAAGATTTTTTGCGCTGAAGCAGCACACT
TGGCGGCAAAAAACGGTATTCAAGTCCATGGTGCAATGGGATACACCTGGGAAGTCGATTTGCAGATGTTTATGAAACGG
ACCTGGGTTTTAGAGTCGACTTGGGGCGATGTGAGCTTTCATAAAGCCAGAGTCAATGAGTTTGTGTTTGACGCAAATAA
CAAAATTGGTCCAGGCCAAACCTTTGGGAGAACATAA

Upstream 100 bases:

>100_bases
TATTTGCGCAAGCGGGTCCTATCTATGCGGGATCTAACGAAATTCAACGCAATATTATTGCGGAACGCATGCTTGGCCTG
CCACGCGCCTAGGGGGAATT

Downstream 100 bases:

>100_bases
TGGCAAATGCTTATATCGTTGATGCGCTTCGCAGCCCAACAGGCCGCCGTAAAGGAGGCTTGTCTCATATACATGCCATT
GATTTAGCGGCTCATTCTTT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MDFTFTEDELAFREAISRFLMTEAAPEALREIWETDTGRSPELRNKIAEQGLTALSIPEEDGGLGLGDVAWSLMTQELGY
YGIPDSLADTAYLAAGVLTARPQTDNLERNQQIKQWLTAIGEGSIRVAVGHPVNPLVADAAVADLLILLDGDDVHAVTRK
DIDVVLRPSIDSSRRLAKVSWQPSRDSLLASGEVGKAIQQQILNRGALSAAGQLLGLAQRMLDLSIDYVAQRKQFGRVIG
SFQAVKHHLADVASKIEMAKPVLYRAAKEFDDESVDSSVYISQAKIFCAEAAHLAAKNGIQVHGAMGYTWEVDLQMFMKR
TWVLESTWGDVSFHKARVNEFVFDANNKIGPGQTFGRT

Sequences:

>Translated_358_residues
MDFTFTEDELAFREAISRFLMTEAAPEALREIWETDTGRSPELRNKIAEQGLTALSIPEEDGGLGLGDVAWSLMTQELGY
YGIPDSLADTAYLAAGVLTARPQTDNLERNQQIKQWLTAIGEGSIRVAVGHPVNPLVADAAVADLLILLDGDDVHAVTRK
DIDVVLRPSIDSSRRLAKVSWQPSRDSLLASGEVGKAIQQQILNRGALSAAGQLLGLAQRMLDLSIDYVAQRKQFGRVIG
SFQAVKHHLADVASKIEMAKPVLYRAAKEFDDESVDSSVYISQAKIFCAEAAHLAAKNGIQVHGAMGYTWEVDLQMFMKR
TWVLESTWGDVSFHKARVNEFVFDANNKIGPGQTFGRT
>Mature_358_residues
MDFTFTEDELAFREAISRFLMTEAAPEALREIWETDTGRSPELRNKIAEQGLTALSIPEEDGGLGLGDVAWSLMTQELGY
YGIPDSLADTAYLAAGVLTARPQTDNLERNQQIKQWLTAIGEGSIRVAVGHPVNPLVADAAVADLLILLDGDDVHAVTRK
DIDVVLRPSIDSSRRLAKVSWQPSRDSLLASGEVGKAIQQQILNRGALSAAGQLLGLAQRMLDLSIDYVAQRKQFGRVIG
SFQAVKHHLADVASKIEMAKPVLYRAAKEFDDESVDSSVYISQAKIFCAEAAHLAAKNGIQVHGAMGYTWEVDLQMFMKR
TWVLESTWGDVSFHKARVNEFVFDANNKIGPGQTFGRT

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=365, Percent_Identity=26.027397260274, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI4557231, Length=365, Percent_Identity=26.027397260274, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI4501859, Length=365, Percent_Identity=22.7397260273973, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4557233, Length=314, Percent_Identity=25.4777070063694, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI21361497, Length=136, Percent_Identity=27.9411764705882, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7656849, Length=169, Percent_Identity=27.2189349112426, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=371, Percent_Identity=26.1455525606469, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=363, Percent_Identity=25.068870523416, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=343, Percent_Identity=24.198250728863, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=366, Percent_Identity=24.0437158469945, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=170, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=117, Percent_Identity=27.3504273504274, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71990804, Length=79, Percent_Identity=43.0379746835443, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=316, Percent_Identity=26.2658227848101, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=22.972972972973, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666513, Length=108, Percent_Identity=37.037037037037, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 39288; Mature: 39288

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTFTEDELAFREAISRFLMTEAAPEALREIWETDTGRSPELRNKIAEQGLTALSIPEE
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCC
DGGLGLGDVAWSLMTQELGYYGIPDSLADTAYLAAGVLTARPQTDNLERNQQIKQWLTAI
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GEGSIRVAVGHPVNPLVADAAVADLLILLDGDDVHAVTRKDIDVVLRPSIDSSRRLAKVS
CCCCEEEEECCCCCHHHHHHHHHHEEEEECCCCEEHHHHCCCCEEEECCCCCCCCEEEEE
WQPSRDSLLASGEVGKAIQQQILNRGALSAAGQLLGLAQRMLDLSIDYVAQRKQFGRVIG
CCCCCCCEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFQAVKHHLADVASKIEMAKPVLYRAAKEFDDESVDSSVYISQAKIFCAEAAHLAAKNGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCC
QVHGAMGYTWEVDLQMFMKRTWVLESTWGDVSFHKARVNEFVFDANNKIGPGQTFGRT
EEEECCCCEEEHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCC
>Mature Secondary Structure
MDFTFTEDELAFREAISRFLMTEAAPEALREIWETDTGRSPELRNKIAEQGLTALSIPEE
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCC
DGGLGLGDVAWSLMTQELGYYGIPDSLADTAYLAAGVLTARPQTDNLERNQQIKQWLTAI
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GEGSIRVAVGHPVNPLVADAAVADLLILLDGDDVHAVTRKDIDVVLRPSIDSSRRLAKVS
CCCCEEEEECCCCCHHHHHHHHHHEEEEECCCCEEHHHHCCCCEEEECCCCCCCCEEEEE
WQPSRDSLLASGEVGKAIQQQILNRGALSAAGQLLGLAQRMLDLSIDYVAQRKQFGRVIG
CCCCCCCEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFQAVKHHLADVASKIEMAKPVLYRAAKEFDDESVDSSVYISQAKIFCAEAAHLAAKNGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCC
QVHGAMGYTWEVDLQMFMKRTWVLESTWGDVSFHKARVNEFVFDANNKIGPGQTFGRT
EEEECCCCEEEHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]