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The map label for this gene is bcd [H]

Identifier: 157961964

GI number: 157961964

Start: 2594861

End: 2596099

Strand: Direct

Name: bcd [H]

Synonym: Spea_2143

Alternate gene names: 157961964

Gene position: 2594861-2596099 (Clockwise)

Preceding gene: 157961963

Following gene: 157961965

Centisome position: 50.15

GC content: 45.68

Gene sequence:

>1239_bases
ATGAGCGATATGGATTTATTTAAAAACGATGTAAAACAGTGGCTAGAAGAAAATTGCCCACATTCTCTCAGAACGCCGAC
TCCGGAGAATGAATTAGTGTGGGGCGGTAAAAACGTAAACTTTGTCACCCAAGATATGCGTGATTGGTTTGAGCGTATGC
GCGATAAACGTTGGTTTTGTCCGGGATGGCCTTCCGAATATGGCGGTGGGGGGTTGTCGGCTACAGAAGTCAATATTCTC
GAGAAAGAAATGCTCCGCATGCGATGCCGTCCACCGCAAATCAATCTAGGAATTTGGATGCTAGGTCCAGTGCTATTAAA
GTATGGTACTGAAGAGCAGAAAAAACGCCTGCTGCTGCCGATGACACAAGGTGAAGTCCGCTGGTGCCAAGGGTTTAGCG
AACCTAATGCCGGCTCAGATCTTGCCAATATCCGGACTAGTGCCGTCGATATGGGCGATCACTTTTTGGTTAATGGCTCT
AAAATTTGGACCTCATACGGCGATAAATCGGACTGGATGTATGCCTTAGTAAGAACCGATAATAACGCCTCGAAGCATGC
AGGGATCAGTTTACTCGCACTCGATATGGCAAGCGCCGGAGTAACGCCTAAAACTATCGATTTAATCAGTGGAAAATCGA
CATTCTGTGAAGTGTTCTTCGATAATGTCAAAGTGCCTAAAGACAACCTTATTGGTGATGTAAACGGTGGCTGGCCGCTA
GCAAAGCTACTGCTTCAGCACGAGCGCAGCGCAATGAGCAAGTTTGGTGAGTTTAGTTTGCCAAATCATTTTCACCTCAA
AACGTTTGTTAACGACTATATGCCCAAGCCTCACACTGTATCGGAAACGATTTTGCATGCACGCACCGTTGTTTGTGATA
TGGAAGAAAGGATCTTTAATTTGACGGTTCAGCGCATGGGAGAAGAAGCTCGTTCTGGAAAGGATGTTTTCCCTACGATG
TCAATTATGAAGTATGCCCATAGTGAACAAGAGAAAGTTAAGTTTGAGTTGCTACTCGATGTGATGGGTTACCGAGCTCT
GGGGTGGCAGCTAGATGGCTGCGCTAACGACAGTTTTAGCGAGCAAGAGCTTAGTGTTACCCGTGGTTGGCTAAATAGCT
TTACGCAAACCATTGCGGGTGGGTCTTCTGAGGTTCAGCTAAATGTGATCGCTAAAAGAGTGCTCAACTTACCTGATAGT
AAAGCGGGATCTTCAGTTAAAAAGGTAACAACATCATGA

Upstream 100 bases:

>100_bases
ACTTTTGGTGGTGGAACAAATGAGATCCAGCGAGAGCTCATTGCGCAATTTGGATTGGGTTTACCCAGAGCACGTAACTA
AAGTTAGAAGGATTTGCATC

Downstream 100 bases:

>100_bases
AGCTAATTTATAACGAAGACGAACGTATGTTGGCTGACACTGCCATAGAGTTTTTGACATCAAAAAGCCCTGTTGCAGCC
AAAAGAGCCTTACGAGATGA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSDMDLFKNDVKQWLEENCPHSLRTPTPENELVWGGKNVNFVTQDMRDWFERMRDKRWFCPGWPSEYGGGGLSATEVNIL
EKEMLRMRCRPPQINLGIWMLGPVLLKYGTEEQKKRLLLPMTQGEVRWCQGFSEPNAGSDLANIRTSAVDMGDHFLVNGS
KIWTSYGDKSDWMYALVRTDNNASKHAGISLLALDMASAGVTPKTIDLISGKSTFCEVFFDNVKVPKDNLIGDVNGGWPL
AKLLLQHERSAMSKFGEFSLPNHFHLKTFVNDYMPKPHTVSETILHARTVVCDMEERIFNLTVQRMGEEARSGKDVFPTM
SIMKYAHSEQEKVKFELLLDVMGYRALGWQLDGCANDSFSEQELSVTRGWLNSFTQTIAGGSSEVQLNVIAKRVLNLPDS
KAGSSVKKVTTS

Sequences:

>Translated_412_residues
MSDMDLFKNDVKQWLEENCPHSLRTPTPENELVWGGKNVNFVTQDMRDWFERMRDKRWFCPGWPSEYGGGGLSATEVNIL
EKEMLRMRCRPPQINLGIWMLGPVLLKYGTEEQKKRLLLPMTQGEVRWCQGFSEPNAGSDLANIRTSAVDMGDHFLVNGS
KIWTSYGDKSDWMYALVRTDNNASKHAGISLLALDMASAGVTPKTIDLISGKSTFCEVFFDNVKVPKDNLIGDVNGGWPL
AKLLLQHERSAMSKFGEFSLPNHFHLKTFVNDYMPKPHTVSETILHARTVVCDMEERIFNLTVQRMGEEARSGKDVFPTM
SIMKYAHSEQEKVKFELLLDVMGYRALGWQLDGCANDSFSEQELSVTRGWLNSFTQTIAGGSSEVQLNVIAKRVLNLPDS
KAGSSVKKVTTS
>Mature_411_residues
SDMDLFKNDVKQWLEENCPHSLRTPTPENELVWGGKNVNFVTQDMRDWFERMRDKRWFCPGWPSEYGGGGLSATEVNILE
KEMLRMRCRPPQINLGIWMLGPVLLKYGTEEQKKRLLLPMTQGEVRWCQGFSEPNAGSDLANIRTSAVDMGDHFLVNGSK
IWTSYGDKSDWMYALVRTDNNASKHAGISLLALDMASAGVTPKTIDLISGKSTFCEVFFDNVKVPKDNLIGDVNGGWPLA
KLLLQHERSAMSKFGEFSLPNHFHLKTFVNDYMPKPHTVSETILHARTVVCDMEERIFNLTVQRMGEEARSGKDVFPTMS
IMKYAHSEQEKVKFELLLDVMGYRALGWQLDGCANDSFSEQELSVTRGWLNSFTQTIAGGSSEVQLNVIAKRVLNLPDSK
AGSSVKKVTTS

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI76496475, Length=202, Percent_Identity=33.1683168316832, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4557235, Length=202, Percent_Identity=33.1683168316832, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI21361497, Length=216, Percent_Identity=31.4814814814815, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4501857, Length=405, Percent_Identity=22.962962962963, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI226958412, Length=202, Percent_Identity=28.2178217821782, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4557231, Length=180, Percent_Identity=31.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI187960098, Length=180, Percent_Identity=31.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226958414, Length=182, Percent_Identity=30.7692307692308, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI4501859, Length=348, Percent_Identity=25.5747126436782, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557233, Length=192, Percent_Identity=31.7708333333333, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI211971008, Length=146, Percent_Identity=31.5068493150685, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI48976061, Length=146, Percent_Identity=31.5068493150685, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7656849, Length=186, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI38505218, Length=148, Percent_Identity=33.1081081081081, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551932, Length=234, Percent_Identity=29.4871794871795, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=243, Percent_Identity=27.5720164609054, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=183, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=189, Percent_Identity=31.2169312169312, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=196, Percent_Identity=31.6326530612245, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=196, Percent_Identity=31.6326530612245, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=184, Percent_Identity=28.804347826087, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=215, Percent_Identity=26.9767441860465, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=190, Percent_Identity=32.1052631578947, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=201, Percent_Identity=27.363184079602, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=189, Percent_Identity=26.4550264550265, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=153, Percent_Identity=32.0261437908497, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=153, Percent_Identity=32.0261437908497, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=190, Percent_Identity=27.8947368421053, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356377, Length=350, Percent_Identity=27.7142857142857, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363737, Length=206, Percent_Identity=31.0679611650485, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646207, Length=180, Percent_Identity=30.5555555555556, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355753, Length=219, Percent_Identity=29.2237442922374, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24666513, Length=156, Percent_Identity=28.2051282051282, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24660351, Length=184, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 46464; Mature: 46332

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDMDLFKNDVKQWLEENCPHSLRTPTPENELVWGGKNVNFVTQDMRDWFERMRDKRWFC
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PGWPSEYGGGGLSATEVNILEKEMLRMRCRPPQINLGIWMLGPVLLKYGTEEQKKRLLLP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHCCEEEE
MTQGEVRWCQGFSEPNAGSDLANIRTSAVDMGDHFLVNGSKIWTSYGDKSDWMYALVRTD
CCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCEEEEEEEEC
NNASKHAGISLLALDMASAGVTPKTIDLISGKSTFCEVFFDNVKVPKDNLIGDVNGGWPL
CCCCHHCCEEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHCEECCCCCHHH
AKLLLQHERSAMSKFGEFSLPNHFHLKTFVNDYMPKPHTVSETILHARTVVCDMEERIFN
HHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTVQRMGEEARSGKDVFPTMSIMKYAHSEQEKVKFELLLDVMGYRALGWQLDGCANDSFS
HHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHCEEECCCCCCCCC
EQELSVTRGWLNSFTQTIAGGSSEVQLNVIAKRVLNLPDSKAGSSVKKVTTS
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCHHHCCCC
>Mature Secondary Structure 
SDMDLFKNDVKQWLEENCPHSLRTPTPENELVWGGKNVNFVTQDMRDWFERMRDKRWFC
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PGWPSEYGGGGLSATEVNILEKEMLRMRCRPPQINLGIWMLGPVLLKYGTEEQKKRLLLP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHCCEEEE
MTQGEVRWCQGFSEPNAGSDLANIRTSAVDMGDHFLVNGSKIWTSYGDKSDWMYALVRTD
CCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCEEEEEEEEC
NNASKHAGISLLALDMASAGVTPKTIDLISGKSTFCEVFFDNVKVPKDNLIGDVNGGWPL
CCCCHHCCEEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHCEECCCCCHHH
AKLLLQHERSAMSKFGEFSLPNHFHLKTFVNDYMPKPHTVSETILHARTVVCDMEERIFN
HHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTVQRMGEEARSGKDVFPTMSIMKYAHSEQEKVKFELLLDVMGYRALGWQLDGCANDSFS
HHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHCEEECCCCCCCCC
EQELSVTRGWLNSFTQTIAGGSSEVQLNVIAKRVLNLPDSKAGSSVKKVTTS
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]