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The map label for this gene is yngJ [H]

Identifier: 157961960

GI number: 157961960

Start: 2590911

End: 2592041

Strand: Direct

Name: yngJ [H]

Synonym: Spea_2139

Alternate gene names: 157961960

Gene position: 2590911-2592041 (Clockwise)

Preceding gene: 157961959

Following gene: 157961961

Centisome position: 50.07

GC content: 45.09

Gene sequence:

>1131_bases
ATGGATTTTTCATTAACCGAAGAGCAGCAAGCGATCTTTGAAATGTCTCAGGGAGTGTTTAACGATTGCTGCACCGATGA
GTACCTACGTGAAGTTGACGATTCAAATATCACCATAATGGATACATTGTGGCAAACCTGTATTGAAACCGGATTACATG
CGCTGTATTTGCCAGAAGAGTATGGCGGAAGTGAATTAGGAATGACCGAACTTGCATTAGTACTACAAGCACAAGGTGCA
GCATTAGGTTTGGTTCCACTTTGGCGCCATCAATTAGCCGGGGCATGTTTAGCCAAGTTTGCTACTGCAGATCTACACCC
CGTTGTGCGCGCAGCAGCTTCTGCTGACAATATATTAACCCTCAGTATGCCAAAGCTTAGCAAGCATAGCGCGTTAGTTA
AGGCGACTCCGAATAAAGAAAACAACGGTTACTTACTTAGCGGTAAATTATCAGCTGTTGCAGACGCAGCTATCGCTAGC
CATGTGTTGATGCCAATTGAAATCGCTAACAAAGTGGGTTTTGCGCTGGTGCAATTAGATGCTGTCAATATAGAGCGTAT
CGATGGAGTACTAACTCAGGGCGAACAAGTTTCAGATCTTGTTTTTAATCAATGCCCAGTATTCGGGCATCAGCTTCTAG
CAGATGGTGCCAGTGAATGGCTTACTCCCAGAGTGCTTGCAGCCTTTAGTGCAATGCAGCTTGGAGTCAGCGAGGAACAG
CTTAAAAGAACCGTTGAATATATCTGTGAGCGTCGTCAATTTGATCGTCAAATTGGCGCATTCCAAGCCGTTCAAATGAC
AATGGCTGATTGTCGTATTGCCTTAGAAGTGCTGCGTTCCACCTTATTGCAACTTTGCTATCGCATTGATGCGGGCCTTG
GTTGTGATTCTGAAGCGCTAGCTTGTGCGCTGCATGCTTGTGATGCAGGACACTTGATAGGCCATAAAGCGCAACATGTT
CATGGCGGTTTCGGTGTAGATATCAGTTATCCAATACATCGTTATTTGTATTGGAGCCGCGCAATATCACTAGGACTTGG
CGGAAGCCAAGCAATAACCGAGCGGTTAGGTGACTGGTTAGCAGAGAATGACAAACTTGGATGGAAGTATGACCTCAATG
AAAACAATTAA

Upstream 100 bases:

>100_bases
TAGTCATTGGTCAAAAAGTTAAAGTGGAGTTCACCACCTACGACGGTGATTTGACACTACCAATGTTCAAACCTGTCAGC
GGATAAAAAGGGGGGATATT

Downstream 100 bases:

>100_bases
TACTAAAAACAGTGTGGCTAGCAACTTTTCAAATGTAAATCTTGGTGACAAATTACCACAGCTTACAATTCCTATCACGG
TTGCATTAATCACTAGTGGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MDFSLTEEQQAIFEMSQGVFNDCCTDEYLREVDDSNITIMDTLWQTCIETGLHALYLPEEYGGSELGMTELALVLQAQGA
ALGLVPLWRHQLAGACLAKFATADLHPVVRAAASADNILTLSMPKLSKHSALVKATPNKENNGYLLSGKLSAVADAAIAS
HVLMPIEIANKVGFALVQLDAVNIERIDGVLTQGEQVSDLVFNQCPVFGHQLLADGASEWLTPRVLAAFSAMQLGVSEEQ
LKRTVEYICERRQFDRQIGAFQAVQMTMADCRIALEVLRSTLLQLCYRIDAGLGCDSEALACALHACDAGHLIGHKAQHV
HGGFGVDISYPIHRYLYWSRAISLGLGGSQAITERLGDWLAENDKLGWKYDLNENN

Sequences:

>Translated_376_residues
MDFSLTEEQQAIFEMSQGVFNDCCTDEYLREVDDSNITIMDTLWQTCIETGLHALYLPEEYGGSELGMTELALVLQAQGA
ALGLVPLWRHQLAGACLAKFATADLHPVVRAAASADNILTLSMPKLSKHSALVKATPNKENNGYLLSGKLSAVADAAIAS
HVLMPIEIANKVGFALVQLDAVNIERIDGVLTQGEQVSDLVFNQCPVFGHQLLADGASEWLTPRVLAAFSAMQLGVSEEQ
LKRTVEYICERRQFDRQIGAFQAVQMTMADCRIALEVLRSTLLQLCYRIDAGLGCDSEALACALHACDAGHLIGHKAQHV
HGGFGVDISYPIHRYLYWSRAISLGLGGSQAITERLGDWLAENDKLGWKYDLNENN
>Mature_376_residues
MDFSLTEEQQAIFEMSQGVFNDCCTDEYLREVDDSNITIMDTLWQTCIETGLHALYLPEEYGGSELGMTELALVLQAQGA
ALGLVPLWRHQLAGACLAKFATADLHPVVRAAASADNILTLSMPKLSKHSALVKATPNKENNGYLLSGKLSAVADAAIAS
HVLMPIEIANKVGFALVQLDAVNIERIDGVLTQGEQVSDLVFNQCPVFGHQLLADGASEWLTPRVLAAFSAMQLGVSEEQ
LKRTVEYICERRQFDRQIGAFQAVQMTMADCRIALEVLRSTLLQLCYRIDAGLGCDSEALACALHACDAGHLIGHKAQHV
HGGFGVDISYPIHRYLYWSRAISLGLGGSQAITERLGDWLAENDKLGWKYDLNENN

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=22.7882037533512, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41095; Mature: 41095

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLTEEQQAIFEMSQGVFNDCCTDEYLREVDDSNITIMDTLWQTCIETGLHALYLPEE
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEHHHHHHHHHHCCCEEEECCHH
YGGSELGMTELALVLQAQGAALGLVPLWRHQLAGACLAKFATADLHPVVRAAASADNILT
CCCCCCCHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEE
LSMPKLSKHSALVKATPNKENNGYLLSGKLSAVADAAIASHVLMPIEIANKVGFALVQLD
EECCCCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEE
AVNIERIDGVLTQGEQVSDLVFNQCPVFGHQLLADGASEWLTPRVLAAFSAMQLGVSEEQ
CCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCHHH
LKRTVEYICERRQFDRQIGAFQAVQMTMADCRIALEVLRSTLLQLCYRIDAGLGCDSEAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ACALHACDAGHLIGHKAQHVHGGFGVDISYPIHRYLYWSRAISLGLGGSQAITERLGDWL
HHHHHHCCCCCHHCCCHHHCCCCCCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AENDKLGWKYDLNENN
HCCCCCCEEECCCCCC
>Mature Secondary Structure
MDFSLTEEQQAIFEMSQGVFNDCCTDEYLREVDDSNITIMDTLWQTCIETGLHALYLPEE
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEHHHHHHHHHHCCCEEEECCHH
YGGSELGMTELALVLQAQGAALGLVPLWRHQLAGACLAKFATADLHPVVRAAASADNILT
CCCCCCCHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEE
LSMPKLSKHSALVKATPNKENNGYLLSGKLSAVADAAIASHVLMPIEIANKVGFALVQLD
EECCCCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEE
AVNIERIDGVLTQGEQVSDLVFNQCPVFGHQLLADGASEWLTPRVLAAFSAMQLGVSEEQ
CCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCHHH
LKRTVEYICERRQFDRQIGAFQAVQMTMADCRIALEVLRSTLLQLCYRIDAGLGCDSEAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ACALHACDAGHLIGHKAQHVHGGFGVDISYPIHRYLYWSRAISLGLGGSQAITERLGDWL
HHHHHHCCCCCHHCCCHHHCCCCCCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AENDKLGWKYDLNENN
HCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]