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The map label for this gene is rsmB [H]

Identifier: 157961827

GI number: 157961827

Start: 2429824

End: 2431041

Strand: Direct

Name: rsmB [H]

Synonym: Spea_2006

Alternate gene names: 157961827

Gene position: 2429824-2431041 (Clockwise)

Preceding gene: 157961826

Following gene: 157961829

Centisome position: 46.96

GC content: 44.83

Gene sequence:

>1218_bases
ATGTTGAAATCTTCGCTATCTCCCAGCTCAAATGAACTTGTGATCAGTATTCTCGACCTTGTTTTATCAGAGGGTAAGCC
GCTTGATCGTGCTTATTCTCAACATTTTTCCGGCTTAAAACTCGAGCCGACAGAGCAGGGGCGTATCACCTTTGTTGTGG
GCGATATACTAAGAAGATTGAACCTTTACTGTTACTTATCAGATGTGACACCTGAAGAGATGGCTCGTTTAGGTTCACGT
CTATTAAATGTTTGGCATCTTTTTAATGAGTTACCTTTGCCTAAAATGCAGTATTCGTTACAAGTCGATACTGCAGATTT
GGCCTCCCGTATCGAGTCTGCTAAAGCGCAACCGGTACTATGGGATGGTTGCCCAGATTGGCTAAACCAAATGGGTGAAG
CTCAGATGGGCGATAAATGGCCTGCAGAAAGAGCTGCGCTAAACAAGCCTGCTAAACGTTTTTTGCGTACAAATATCCTA
AAGTGCACACGCGATGAACTTGCCAATGCGCTACGTAAAGAGGGAGTGCAAACGGCTAGCGTTGAAGGCGTCGATACAGC
CTTAGAAGTTGTTTCTGATTCTGCATTATTTAGAACCGAAGCCTTTAAGAAAGGTTGGTTTGAGCAGCAAGATGCCGGTT
CTCAATTAGTGGCATTAGCGCTTGATGCAAAGCCTGGAATGAGAGTCGTAGATGCGTGTGCAGGTGCTGGTGGTAAAACC
TTATCTATTTCTGCACAAATGCAGGGAAAAGGTCGTTTACTCGCGATGGACGTAGAGCAATGGAAACTTGATAACCTGAA
GCAGCGTGCGCGCCGAGCAGGTGCTCATAACGTAGAAACTCGAATTATCGCCAGCAGTAAGACCATTAAGCGTTTGAAGC
TAACCGCTGACAGAGTGTTACTAGACGTACCATGCTCTGGTTTAGGCGTACTGAAGCGTAACCCTGACGCAAAATGGCGT
GATACCCCAGAGCGCTTACCTGTACTGGTCGAGCTTCAAAAGCATATTTTGCAAAGCTATAGTCGTATGGTGAAAGTAGG
CGGCATATTGGTTTATGCGACATGCTCAATTATGCCAGAAGAGAACCGCGATCAAATTGACGCATTTCTTGCTGAGAATA
AGCACTTCAGATTCATCGAAGATGAGACAATAAGCCCAGCAGAAACCGGTTTTGATGGTTTCTACTTAGCAAAATTAGAG
CGTATATCAGAAGAATAA

Upstream 100 bases:

>100_bases
TAAGCAACCGCTTTTATTATAGGATTTGGAGCTGTTAGCTTGCGTATTTTAAGCTTTGCTCCTATGATCCCAGCGTTTTC
TATTTACGGTAACTTTTTTA

Downstream 100 bases:

>100_bases
TAGTCTGGTAGAAATAGATTGAATAAAAAGAGCACCTTAGGTGCTCTTTTTTGTACTCAAATAGGGCGAGCCACTAAAAA
GTCTTTCTATGAGTATTATC

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MLKSSLSPSSNELVISILDLVLSEGKPLDRAYSQHFSGLKLEPTEQGRITFVVGDILRRLNLYCYLSDVTPEEMARLGSR
LLNVWHLFNELPLPKMQYSLQVDTADLASRIESAKAQPVLWDGCPDWLNQMGEAQMGDKWPAERAALNKPAKRFLRTNIL
KCTRDELANALRKEGVQTASVEGVDTALEVVSDSALFRTEAFKKGWFEQQDAGSQLVALALDAKPGMRVVDACAGAGGKT
LSISAQMQGKGRLLAMDVEQWKLDNLKQRARRAGAHNVETRIIASSKTIKRLKLTADRVLLDVPCSGLGVLKRNPDAKWR
DTPERLPVLVELQKHILQSYSRMVKVGGILVYATCSIMPEENRDQIDAFLAENKHFRFIEDETISPAETGFDGFYLAKLE
RISEE

Sequences:

>Translated_405_residues
MLKSSLSPSSNELVISILDLVLSEGKPLDRAYSQHFSGLKLEPTEQGRITFVVGDILRRLNLYCYLSDVTPEEMARLGSR
LLNVWHLFNELPLPKMQYSLQVDTADLASRIESAKAQPVLWDGCPDWLNQMGEAQMGDKWPAERAALNKPAKRFLRTNIL
KCTRDELANALRKEGVQTASVEGVDTALEVVSDSALFRTEAFKKGWFEQQDAGSQLVALALDAKPGMRVVDACAGAGGKT
LSISAQMQGKGRLLAMDVEQWKLDNLKQRARRAGAHNVETRIIASSKTIKRLKLTADRVLLDVPCSGLGVLKRNPDAKWR
DTPERLPVLVELQKHILQSYSRMVKVGGILVYATCSIMPEENRDQIDAFLAENKHFRFIEDETISPAETGFDGFYLAKLE
RISEE
>Mature_405_residues
MLKSSLSPSSNELVISILDLVLSEGKPLDRAYSQHFSGLKLEPTEQGRITFVVGDILRRLNLYCYLSDVTPEEMARLGSR
LLNVWHLFNELPLPKMQYSLQVDTADLASRIESAKAQPVLWDGCPDWLNQMGEAQMGDKWPAERAALNKPAKRFLRTNIL
KCTRDELANALRKEGVQTASVEGVDTALEVVSDSALFRTEAFKKGWFEQQDAGSQLVALALDAKPGMRVVDACAGAGGKT
LSISAQMQGKGRLLAMDVEQWKLDNLKQRARRAGAHNVETRIIASSKTIKRLKLTADRVLLDVPCSGLGVLKRNPDAKWR
DTPERLPVLVELQKHILQSYSRMVKVGGILVYATCSIMPEENRDQIDAFLAENKHFRFIEDETISPAETGFDGFYLAKLE
RISEE

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=280, Percent_Identity=31.4285714285714, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI76150623, Length=280, Percent_Identity=31.4285714285714, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI32698918, Length=229, Percent_Identity=29.2576419213974, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI270288818, Length=295, Percent_Identity=27.4576271186441, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI23199998, Length=295, Percent_Identity=27.4576271186441, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI8922322, Length=295, Percent_Identity=27.4576271186441, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI270288816, Length=295, Percent_Identity=27.4576271186441, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI39995082, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI301336155, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI2367212, Length=287, Percent_Identity=31.7073170731707, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081985, Length=224, Percent_Identity=29.9107142857143, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17536757, Length=293, Percent_Identity=29.6928327645051, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71998419, Length=246, Percent_Identity=29.2682926829268, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534021, Length=167, Percent_Identity=32.9341317365269, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324268, Length=280, Percent_Identity=29.2857142857143, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319447, Length=175, Percent_Identity=29.7142857142857, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI22024126, Length=279, Percent_Identity=29.3906810035842, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355201, Length=175, Percent_Identity=31.4285714285714, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19920494, Length=166, Percent_Identity=34.9397590361446, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 45214; Mature: 45214

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSSLSPSSNELVISILDLVLSEGKPLDRAYSQHFSGLKLEPTEQGRITFVVGDILRRL
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHC
NLYCYLSDVTPEEMARLGSRLLNVWHLFNELPLPKMQYSLQVDTADLASRIESAKAQPVL
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCEE
WDGCPDWLNQMGEAQMGDKWPAERAALNKPAKRFLRTNILKCTRDELANALRKEGVQTAS
ECCCHHHHHHHCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
VEGVDTALEVVSDSALFRTEAFKKGWFEQQDAGSQLVALALDAKPGMRVVDACAGAGGKT
CCCHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCE
LSISAQMQGKGRLLAMDVEQWKLDNLKQRARRAGAHNVETRIIASSKTIKRLKLTADRVL
EEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHEE
LDVPCSGLGVLKRNPDAKWRDTPERLPVLVELQKHILQSYSRMVKVGGILVYATCSIMPE
EECCCCCCCCEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
ENRDQIDAFLAENKHFRFIEDETISPAETGFDGFYLAKLERISEE
CCHHHHHHHHHCCCCEEEECCCCCCCHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLKSSLSPSSNELVISILDLVLSEGKPLDRAYSQHFSGLKLEPTEQGRITFVVGDILRRL
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHC
NLYCYLSDVTPEEMARLGSRLLNVWHLFNELPLPKMQYSLQVDTADLASRIESAKAQPVL
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCEE
WDGCPDWLNQMGEAQMGDKWPAERAALNKPAKRFLRTNILKCTRDELANALRKEGVQTAS
ECCCHHHHHHHCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
VEGVDTALEVVSDSALFRTEAFKKGWFEQQDAGSQLVALALDAKPGMRVVDACAGAGGKT
CCCHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCE
LSISAQMQGKGRLLAMDVEQWKLDNLKQRARRAGAHNVETRIIASSKTIKRLKLTADRVL
EEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHEE
LDVPCSGLGVLKRNPDAKWRDTPERLPVLVELQKHILQSYSRMVKVGGILVYATCSIMPE
EECCCCCCCCEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
ENRDQIDAFLAENKHFRFIEDETISPAETGFDGFYLAKLERISEE
CCHHHHHHHHHCCCCEEEECCCCCCCHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]