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The map label for this gene is ycfH [H]

Identifier: 157961749

GI number: 157961749

Start: 2335962

End: 2336750

Strand: Direct

Name: ycfH [H]

Synonym: Spea_1926

Alternate gene names: 157961749

Gene position: 2335962-2336750 (Clockwise)

Preceding gene: 157961748

Following gene: 157961751

Centisome position: 45.14

GC content: 43.73

Gene sequence:

>789_bases
GTGCTTATCGATTCACATTGTCACTTAGACCGTTTAAAAATTGCCCCAGATCAGGCTTCACTTCAAGAGGTTATCTCCGC
TGCCAAAGCACGGGATATTGCTTACTTTCTTTGTGTTAACGTAAGACAGCAAGGTTTTATCGATATGAAGCAGAAAATGG
CTGCATTCGATGAAGTGTTCCTATCTGCCGGAGTGCATCCGTTAGATGTACAAGATGGCTTAAATATTCAAGAGGTTGAG
CAGTTTGCTCGTGATGAAAAAGTCGTTGCAATCGGTGAAACGGGTTTAGATTATTTCTACGCCAATGAAACAAAAGCATT
ACAGCAGACCTGCTTTGAGCAGCAGATTGATCTCGCGGTAAAAGTGAATAAGCCACTTATTATTCACACTCGTGATGCGC
GTGAAGATACCATTAATTTTTTGAAGCGTGGTAAAGCGGACACTGTCGGCGGTGTTCTGCACTGTTTTACCGAAGATTGG
GAAATGGCAAAGGCCGCAATAGACTTAGGTTTCTACATTTCGGTTTCGGGCATTGTAACCTTTAAAAACGCGGGTGAATT
GCGTAACGTGATAAGAAAAGTGCCTAAAGATAGGTTACTGGTGGAGACGGATTCCCCCTATCTAGCACCCGTTCCTCATC
GAGGTAAAGAAAACCAACCTGCTTTTGTACGCGATGTCGCTGAGTTTGTGGCAGAGCTAAGAGGGGAGAAATATCCTGAA
TTAGCGCAGTACACAACTGAGAACTTCTTTACTTTATTTAAAGATGCCGCAAGGTTGGCTGGTCGCTGA

Upstream 100 bases:

>100_bases
CGAGCAATTGCTTTCCGGTGAGCTTGCCTCCGGCGATTTGACCTGCACCATGTAGCTGGGTAGACTTGCTGTCCTTTTTG
TAGTTTGTTGGACTTCCACC

Downstream 100 bases:

>100_bases
TACCAAAGTGTTTCGCATAAATTTTAGACAAAAAAAAGACCCAAAACTATTCCGATTGTTATGGGTCTAGGGGAATGGCT
CACTAGGAGCCGTGCGCTAC

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLIDSHCHLDRLKIAPDQASLQEVISAAKARDIAYFLCVNVRQQGFIDMKQKMAAFDEVFLSAGVHPLDVQDGLNIQEVE
QFARDEKVVAIGETGLDYFYANETKALQQTCFEQQIDLAVKVNKPLIIHTRDAREDTINFLKRGKADTVGGVLHCFTEDW
EMAKAAIDLGFYISVSGIVTFKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
LAQYTTENFFTLFKDAARLAGR

Sequences:

>Translated_262_residues
MLIDSHCHLDRLKIAPDQASLQEVISAAKARDIAYFLCVNVRQQGFIDMKQKMAAFDEVFLSAGVHPLDVQDGLNIQEVE
QFARDEKVVAIGETGLDYFYANETKALQQTCFEQQIDLAVKVNKPLIIHTRDAREDTINFLKRGKADTVGGVLHCFTEDW
EMAKAAIDLGFYISVSGIVTFKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
LAQYTTENFFTLFKDAARLAGR
>Mature_262_residues
MLIDSHCHLDRLKIAPDQASLQEVISAAKARDIAYFLCVNVRQQGFIDMKQKMAAFDEVFLSAGVHPLDVQDGLNIQEVE
QFARDEKVVAIGETGLDYFYANETKALQQTCFEQQIDLAVKVNKPLIIHTRDAREDTINFLKRGKADTVGGVLHCFTEDW
EMAKAAIDLGFYISVSGIVTFKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
LAQYTTENFFTLFKDAARLAGR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=219, Percent_Identity=30.5936073059361, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI110349730, Length=272, Percent_Identity=28.3088235294118, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI14042943, Length=270, Percent_Identity=27.4074074074074, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI110349734, Length=272, Percent_Identity=28.3088235294118, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061853, Length=279, Percent_Identity=27.9569892473118, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI225903439, Length=228, Percent_Identity=28.5087719298246, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=28.2945736434109, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI226061595, Length=236, Percent_Identity=27.9661016949153, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787342, Length=259, Percent_Identity=54.4401544401544, Blast_Score=283, Evalue=8e-78,
Organism=Escherichia coli, GI48994985, Length=211, Percent_Identity=36.0189573459716, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=30.7392996108949, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=277, Percent_Identity=29.2418772563177, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=30.3370786516854, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17543026, Length=292, Percent_Identity=27.7397260273973, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=216, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24586117, Length=250, Percent_Identity=30.8, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI221330018, Length=250, Percent_Identity=30.8, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24648690, Length=228, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29526; Mature: 29526

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSHCHLDRLKIAPDQASLQEVISAAKARDIAYFLCVNVRQQGFIDMKQKMAAFDEVF
CEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEEEECCHHCCHHHHHHHHHHHHHHH
LSAGVHPLDVQDGLNIQEVEQFARDEKVVAIGETGLDYFYANETKALQQTCFEQQIDLAV
HHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHCCEEE
KVNKPLIIHTRDAREDTINFLKRGKADTVGGVLHCFTEDWEMAKAAIDLGFYISVSGIVT
EECCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEE
FKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
ECCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
LAQYTTENFFTLFKDAARLAGR
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIDSHCHLDRLKIAPDQASLQEVISAAKARDIAYFLCVNVRQQGFIDMKQKMAAFDEVF
CEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEEEECCHHCCHHHHHHHHHHHHHHH
LSAGVHPLDVQDGLNIQEVEQFARDEKVVAIGETGLDYFYANETKALQQTCFEQQIDLAV
HHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHCCEEE
KVNKPLIIHTRDAREDTINFLKRGKADTVGGVLHCFTEDWEMAKAAIDLGFYISVSGIVT
EECCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEE
FKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
ECCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
LAQYTTENFFTLFKDAARLAGR
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]