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The map label for this gene is udk [H]

Identifier: 157961742

GI number: 157961742

Start: 2331226

End: 2331861

Strand: Direct

Name: udk [H]

Synonym: Spea_1919

Alternate gene names: 157961742

Gene position: 2331226-2331861 (Clockwise)

Preceding gene: 157961741

Following gene: 157961743

Centisome position: 45.05

GC content: 45.13

Gene sequence:

>636_bases
ATGAATTCTAAAGATTGTGTTGTTATTGGTATTGCGGGTGCTTCTGCATCGGGTAAGAGTCTTATCGCGAAAACGATTTA
TGAAGAACTCTGTCGTGACTTAGGTACAGATCAAATTGGCGTGATTGCAGAAGATGCATATTATCGCGACCAAGGTCACC
TATCGATGGACCAACGTGTTTTGACAAACTATGACCACCCTAAAGCTTTGGACCACGAGTTATTATGTAGCCACTTGCGT
GAGCTTAAAGCGGGCAATGCTGTCGACATTCCTGTCTATAGCTATACAGAACACACTCGCACTGACGAGAAAGTGACCCT
GACTCCTAAAAAGGTCATTATTCTTGAAGGGATCTTGTTACTTACCGATCCTGCTTTGCGTAAAGAGATGGATGCGTCTG
TATTTATGGACACACCGCTCGATATCTGCTTTATGCGCAGACTTTCTCGTGATGTGGCTGAGCGAGGCCGAACCATGCAG
TCGGTAATGTCACAGTACACTGAGACCGTTCGCCCAATGTTTTTGCAGTTCATTGAGCCATCAAAGCAGTACGCAGATAT
CATTGTCCCGCGCGGTGGTAAAAACCGTATCGCAACGGATATTTTAAAGGCGCGAATTCAGCACCTTTTAGCATAA

Upstream 100 bases:

>100_bases
ATCGTGAAATCGCGAGAAAAGTTGGGGCTCAGCTTGCACTATGTCAAGCACAGCCAAAAGTATCAATCAGCATGTCTGAT
GACGAATAAAGGTTAGTTTA

Downstream 100 bases:

>100_bases
GCTCACGACTTAAAATGTAAGGGCCCCGGCGATTATGCAATTAACTGACATTGAGATTGAAGACAGCTTAGATAATGGCA
CCACCATCATGGAGCCACGT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRVLTNYDHPKALDHELLCSHLR
ELKAGNAVDIPVYSYTEHTRTDEKVTLTPKKVIILEGILLLTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTMQ
SVMSQYTETVRPMFLQFIEPSKQYADIIVPRGGKNRIATDILKARIQHLLA

Sequences:

>Translated_211_residues
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRVLTNYDHPKALDHELLCSHLR
ELKAGNAVDIPVYSYTEHTRTDEKVTLTPKKVIILEGILLLTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTMQ
SVMSQYTETVRPMFLQFIEPSKQYADIIVPRGGKNRIATDILKARIQHLLA
>Mature_211_residues
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRVLTNYDHPKALDHELLCSHLR
ELKAGNAVDIPVYSYTEHTRTDEKVTLTPKKVIILEGILLLTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTMQ
SVMSQYTETVRPMFLQFIEPSKQYADIIVPRGGKNRIATDILKARIQHLLA

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=210, Percent_Identity=38.5714285714286, Blast_Score=160, Evalue=8e-40,
Organism=Homo sapiens, GI57863312, Length=210, Percent_Identity=38.5714285714286, Blast_Score=160, Evalue=9e-40,
Organism=Homo sapiens, GI18699734, Length=217, Percent_Identity=36.405529953917, Blast_Score=159, Evalue=1e-39,
Organism=Homo sapiens, GI13899253, Length=211, Percent_Identity=33.175355450237, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI209863022, Length=148, Percent_Identity=29.0540540540541, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI87082034, Length=209, Percent_Identity=70.8133971291866, Blast_Score=314, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17539894, Length=210, Percent_Identity=36.6666666666667, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17539892, Length=210, Percent_Identity=36.6666666666667, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71981181, Length=210, Percent_Identity=34.7619047619048, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324339, Length=149, Percent_Identity=33.5570469798658, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24649624, Length=214, Percent_Identity=37.3831775700935, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28573516, Length=204, Percent_Identity=39.2156862745098, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28573514, Length=204, Percent_Identity=39.2156862745098, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28573512, Length=204, Percent_Identity=39.2156862745098, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI45550449, Length=204, Percent_Identity=39.2156862745098, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI221458995, Length=213, Percent_Identity=37.0892018779343, Blast_Score=153, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23770; Mature: 23770

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRV
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCHHHHH
LTNYDHPKALDHELLCSHLRELKAGNAVDIPVYSYTEHTRTDEKVTLTPKKVIILEGILL
HHCCCCCCCCCHHHHHHHHHHHCCCCEEECCEEECCCCCCCCCEEEECCCEEHHHHHHHH
LTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTMQSVMSQYTETVRPMFLQFIEP
HCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKQYADIIVPRGGKNRIATDILKARIQHLLA
CHHHHEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRV
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCHHHHH
LTNYDHPKALDHELLCSHLRELKAGNAVDIPVYSYTEHTRTDEKVTLTPKKVIILEGILL
HHCCCCCCCCCHHHHHHHHHHHCCCCEEECCEEECCCCCCCCCEEEECCCEEHHHHHHHH
LTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTMQSVMSQYTETVRPMFLQFIEP
HCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKQYADIIVPRGGKNRIATDILKARIQHLLA
CHHHHEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA