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The map label for this gene is rhtC [H]

Identifier: 157961581

GI number: 157961581

Start: 2136378

End: 2137022

Strand: Reverse

Name: rhtC [H]

Synonym: Spea_1757

Alternate gene names: 157961581

Gene position: 2137022-2136378 (Counterclockwise)

Preceding gene: 157961583

Following gene: 157961578

Centisome position: 41.3

GC content: 44.81

Gene sequence:

>645_bases
ATGGAATTTCAATTACTTATATCACTGTCCATGATACACCTTATTGCTCTAGCCAGCCCTGGGCCAGATTTTGCTTTAGT
GGTTCGCCTCGCGACTCAAGAGTCTCGCGTGGCAGCCGTTGCCTCAGCATTTGGCATAGCAGTAGCGATTCTTGGGCACA
CCCTGCTTAGTTTAACTGGGGTTAGTCTTATCATTCAAAGCTCAGATGTTTTATTCACCATCGTTCAGTTAGCTGGTGCC
AGTTATTTAGCCTTGATGGGCGTTGGCGCAATAAAATCGGCATGGCTACACTGGCAAGATCCAGTATCGATTGAGACATG
TGTACAAGGGGAAGGAGTAACCGCTTATAAAGGCTTTATGCAGGGGCTCTATACCAATATTTTGAATCCCAAAGCCTTAG
TGTTTTTTATCACCCTATTTTCAACCCTTATTACACCTCAGGTTAGCTTTTCCACCAAGAGCATGGCGGCTTTCTTGCTG
TTTTCCTTATCCTTTATCTGGTTCAGTTTTATTGCAATAGTGCTGTCGAAGCCCAGAGTTCAGCTTAAAATGAAAAAGGT
CAGTCCGCTAATTAATCTCGTCACTGGGTTGGTGTTTATAGGGGTGGCCCTGATGATTATCTCTGGCCTCGTGACATCGC
ACTAA

Upstream 100 bases:

>100_bases
GTTAAATAAAACCTCACTGCACTAAATTCTGCACTAAAGCTGCTCGAACTTTTAGTCACTCCGCAATTAATCAGTAGCAA
ATTAAACAACTAGGTCTCAG

Downstream 100 bases:

>100_bases
CCTTTAGCACTAACTTTTAGTACAAGCCGCTATGATAAGCGGCTCATACCTAAAGGTTACACTAGTTGATACTTCTCTAA
GCGATACAAAAACGCTTTAT

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MEFQLLISLSMIHLIALASPGPDFALVVRLATQESRVAAVASAFGIAVAILGHTLLSLTGVSLIIQSSDVLFTIVQLAGA
SYLALMGVGAIKSAWLHWQDPVSIETCVQGEGVTAYKGFMQGLYTNILNPKALVFFITLFSTLITPQVSFSTKSMAAFLL
FSLSFIWFSFIAIVLSKPRVQLKMKKVSPLINLVTGLVFIGVALMIISGLVTSH

Sequences:

>Translated_214_residues
MEFQLLISLSMIHLIALASPGPDFALVVRLATQESRVAAVASAFGIAVAILGHTLLSLTGVSLIIQSSDVLFTIVQLAGA
SYLALMGVGAIKSAWLHWQDPVSIETCVQGEGVTAYKGFMQGLYTNILNPKALVFFITLFSTLITPQVSFSTKSMAAFLL
FSLSFIWFSFIAIVLSKPRVQLKMKKVSPLINLVTGLVFIGVALMIISGLVTSH
>Mature_214_residues
MEFQLLISLSMIHLIALASPGPDFALVVRLATQESRVAAVASAFGIAVAILGHTLLSLTGVSLIIQSSDVLFTIVQLAGA
SYLALMGVGAIKSAWLHWQDPVSIETCVQGEGVTAYKGFMQGLYTNILNPKALVFFITLFSTLITPQVSFSTKSMAAFLL
FSLSFIWFSFIAIVLSKPRVQLKMKKVSPLINLVTGLVFIGVALMIISGLVTSH

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=207, Percent_Identity=28.9855072463768, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786522, Length=204, Percent_Identity=25.4901960784314, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22950; Mature: 22950

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFQLLISLSMIHLIALASPGPDFALVVRLATQESRVAAVASAFGIAVAILGHTLLSLTG
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLIIQSSDVLFTIVQLAGASYLALMGVGAIKSAWLHWQDPVSIETCVQGEGVTAYKGFM
HHHEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHH
QGLYTNILNPKALVFFITLFSTLITPQVSFSTKSMAAFLLFSLSFIWFSFIAIVLSKPRV
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QLKMKKVSPLINLVTGLVFIGVALMIISGLVTSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFQLLISLSMIHLIALASPGPDFALVVRLATQESRVAAVASAFGIAVAILGHTLLSLTG
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLIIQSSDVLFTIVQLAGASYLALMGVGAIKSAWLHWQDPVSIETCVQGEGVTAYKGFM
HHHEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHH
QGLYTNILNPKALVFFITLFSTLITPQVSFSTKSMAAFLLFSLSFIWFSFIAIVLSKPRV
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QLKMKKVSPLINLVTGLVFIGVALMIISGLVTSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]