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The map label for this gene is mdtA [H]

Identifier: 157961153

GI number: 157961153

Start: 1620120

End: 1621232

Strand: Reverse

Name: mdtA [H]

Synonym: Spea_1325

Alternate gene names: 157961153

Gene position: 1621232-1620120 (Counterclockwise)

Preceding gene: 157961155

Following gene: 157961152

Centisome position: 31.33

GC content: 47.26

Gene sequence:

>1113_bases
ATGAATATCAAGCGCGTTATCACTCGTCAAAAGCTGCTCATAAGCTTGGTAGCAGTTACTTTTTTGCCTGGATGCCAAGA
GTCGCCAGACGAGCAAACTTCAGCGCCAAGTTACCAATCTGTTAATGCAGAGTCACTTAGCCTTAAACAAGGGTACCAGT
TCAGCCAAGTGTTCTCTGGCAGTGTTCGAGCCGGTAATACCACTGGAATTGGCTTTGAGTTAGCGGGGAAGATTAAAGCC
CTCGGCGTCGATAGTGGTGACAAGGTTAAACAAGGCCAGCTACTGGCAAAACTTGATACCCGACTATTGATGGCCGAAAA
AAATGAGCTAACAGCCAGCCTAGCGCAAAATAAGGCCGACTTGGATTTAGCCAAAGCAACATTAGATCGCAGCTTAGGCC
TACAGAAACAAGGTTATGTATCAGAGCAACAACTCGATGAACTCAAAGGTCAGTTGAGCAGCTTGCAAGCCGCTAAGACT
CGACTCAATGCCTCATTACTTGCCAATCAGTTAAAAATCGAGAAATCGGATCTACTGGCTCCATTCGATGGCGTTATCAG
CAAGCGCAGCCATAACTTAGGAGAAGTGATCAATGTTGGCAGCCCCGTTTATACCTTAATTGAGCACAACAATGTACAAG
CCTATATTGGCGTACCCGTTGAAATCGCGGCGCAGTTAAAAACCGGGCAAACCGTTGCTGTAACGGTAAGGCAGCGAGAT
TACCAGGCTAGCATTGCCGGTATTGGCGCCGAGCTCGATCCAGTAACACGAACCGTCGAGTTGAGATTAACCCTGCCAAC
CAATGCCAAGCTGATAAACGGTGAGCTTAGCTACCTTAATTACAATAAAGTGATAGATACCCAAGGCTACTGGGTGCCGC
TTTCGGCGCTAACCGATGGCGTACGTGGGCTGTGGAATATTTACATCATTAGCCCATCGGATGAGCAACTCTTTAGTATC
GAGCGCCGCGATGTTGAGATTGTCTATGCCGCCAAAGATAAAGCCTTTATCAAGGGAGCTATTAGTCCTGATGAGCAGTA
TGTTTCACAGGGATTACATAAACTCGTTGCAGGCCAGCTTGTGACTCGACAAGCAAAATTAGCGACGAGGTAG

Upstream 100 bases:

>100_bases
GACTGGACAGTCTAGTTTTGTCGCACTAGACTAGACAGTCCAGCTTAACAAATTATTTACCCTGCAGTCACTTTTGCATA
AACAACATAGGCTGAACCGA

Downstream 100 bases:

>100_bases
AGCAGATGGTAAAATCATTAGTTGAGAACGGCCGCCTGATAAGCCTCGTCATTGCGCTGTTGATTGTTGCCGGGTTTGGC
GCCATATCTAGCCTACCCCG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNIKRVITRQKLLISLVAVTFLPGCQESPDEQTSAPSYQSVNAESLSLKQGYQFSQVFSGSVRAGNTTGIGFELAGKIKA
LGVDSGDKVKQGQLLAKLDTRLLMAEKNELTASLAQNKADLDLAKATLDRSLGLQKQGYVSEQQLDELKGQLSSLQAAKT
RLNASLLANQLKIEKSDLLAPFDGVISKRSHNLGEVINVGSPVYTLIEHNNVQAYIGVPVEIAAQLKTGQTVAVTVRQRD
YQASIAGIGAELDPVTRTVELRLTLPTNAKLINGELSYLNYNKVIDTQGYWVPLSALTDGVRGLWNIYIISPSDEQLFSI
ERRDVEIVYAAKDKAFIKGAISPDEQYVSQGLHKLVAGQLVTRQAKLATR

Sequences:

>Translated_370_residues
MNIKRVITRQKLLISLVAVTFLPGCQESPDEQTSAPSYQSVNAESLSLKQGYQFSQVFSGSVRAGNTTGIGFELAGKIKA
LGVDSGDKVKQGQLLAKLDTRLLMAEKNELTASLAQNKADLDLAKATLDRSLGLQKQGYVSEQQLDELKGQLSSLQAAKT
RLNASLLANQLKIEKSDLLAPFDGVISKRSHNLGEVINVGSPVYTLIEHNNVQAYIGVPVEIAAQLKTGQTVAVTVRQRD
YQASIAGIGAELDPVTRTVELRLTLPTNAKLINGELSYLNYNKVIDTQGYWVPLSALTDGVRGLWNIYIISPSDEQLFSI
ERRDVEIVYAAKDKAFIKGAISPDEQYVSQGLHKLVAGQLVTRQAKLATR
>Mature_370_residues
MNIKRVITRQKLLISLVAVTFLPGCQESPDEQTSAPSYQSVNAESLSLKQGYQFSQVFSGSVRAGNTTGIGFELAGKIKA
LGVDSGDKVKQGQLLAKLDTRLLMAEKNELTASLAQNKADLDLAKATLDRSLGLQKQGYVSEQQLDELKGQLSSLQAAKT
RLNASLLANQLKIEKSDLLAPFDGVISKRSHNLGEVINVGSPVYTLIEHNNVQAYIGVPVEIAAQLKTGQTVAVTVRQRD
YQASIAGIGAELDPVTRTVELRLTLPTNAKLINGELSYLNYNKVIDTQGYWVPLSALTDGVRGLWNIYIISPSDEQLFSI
ERRDVEIVYAAKDKAFIKGAISPDEQYVSQGLHKLVAGQLVTRQAKLATR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=317, Percent_Identity=23.0283911671924, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789929, Length=374, Percent_Identity=22.9946524064171, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40268; Mature: 40268

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKRVITRQKLLISLVAVTFLPGCQESPDEQTSAPSYQSVNAESLSLKQGYQFSQVFSG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHCC
SVRAGNTTGIGFELAGKIKALGVDSGDKVKQGQLLAKLDTRLLMAEKNELTASLAQNKAD
CCCCCCCCCCCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHEEECCHHHHHHHHCCCCH
LDLAKATLDRSLGLQKQGYVSEQQLDELKGQLSSLQAAKTRLNASLLANQLKIEKSDLLA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHCCC
PFDGVISKRSHNLGEVINVGSPVYTLIEHNNVQAYIGVPVEIAAQLKTGQTVAVTVRQRD
CHHHHHHHCCCCCHHHHCCCCCEEEEEECCCEEEEECCCCEEEEEECCCCEEEEEEECCC
YQASIAGIGAELDPVTRTVELRLTLPTNAKLINGELSYLNYNKVIDTQGYWVPLSALTDG
CCHHHHHCCCCCCCCEEEEEEEEECCCCCEEECCEEEEEEECEEECCCCCEEEHHHHHHC
VRGLWNIYIISPSDEQLFSIERRDVEIVYAAKDKAFIKGAISPDEQYVSQGLHKLVAGQL
CCCEEEEEEECCCCCHHEEEECCCEEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHH
VTRQAKLATR
HHHHHHHCCC
>Mature Secondary Structure
MNIKRVITRQKLLISLVAVTFLPGCQESPDEQTSAPSYQSVNAESLSLKQGYQFSQVFSG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHCC
SVRAGNTTGIGFELAGKIKALGVDSGDKVKQGQLLAKLDTRLLMAEKNELTASLAQNKAD
CCCCCCCCCCCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHEEECCHHHHHHHHCCCCH
LDLAKATLDRSLGLQKQGYVSEQQLDELKGQLSSLQAAKTRLNASLLANQLKIEKSDLLA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHCCC
PFDGVISKRSHNLGEVINVGSPVYTLIEHNNVQAYIGVPVEIAAQLKTGQTVAVTVRQRD
CHHHHHHHCCCCCHHHHCCCCCEEEEEECCCEEEEECCCCEEEEEECCCCEEEEEEECCC
YQASIAGIGAELDPVTRTVELRLTLPTNAKLINGELSYLNYNKVIDTQGYWVPLSALTDG
CCHHHHHCCCCCCCCEEEEEEEEECCCCCEEECCEEEEEEECEEECCCCCEEEHHHHHHC
VRGLWNIYIISPSDEQLFSIERRDVEIVYAAKDKAFIKGAISPDEQYVSQGLHKLVAGQL
CCCEEEEEEECCCCCHHEEEECCCEEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHH
VTRQAKLATR
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]