Click here to switch to the map view.

The map label for this gene is luxQ [H]

Identifier: 157961005

GI number: 157961005

Start: 1426483

End: 1428723

Strand: Reverse

Name: luxQ [H]

Synonym: Spea_1177

Alternate gene names: 157961005

Gene position: 1428723-1426483 (Counterclockwise)

Preceding gene: 157961007

Following gene: 157961004

Centisome position: 27.61

GC content: 46.36

Gene sequence:

>2241_bases
ATGACCGCTCAACAAATGGCTAAACCTGTTGTCTTTCTGTTGCTATTCACTGGCTTATCAAGCTCGCTATTAGCACATTC
TTTTGAACTCAAACCACAAGAGCAGCTACAGCCAAAAACACTGGTTACAGCGCCCACCGTTACGGCAGGTCAAGAGTCTA
TCGCACTCACTAGCCAACTTAAGTACGACGAAACCCTATCAAGGTTTTTCCAGTTGATCTTATTTACGCTTATTTCTCTA
GTGCTAGCGCTTAACTTCTTGCGGAGTAAAAAACGTAAAGTGTTTTTATCACAAGCCCTTGCCAGTGGCCAAGCCAGTCA
TGATCAGATGCAGTGGTTAATGGCCGTACTGGATAATTTTCCCGGCATGGTGTTGATCTCTGACGCCAACGGCAAACCAA
TGTTAGCCAACAAGGCCTATAACACCTGCGTACAGAGCGGCTCAGCGACCAATCCCGACTCAATTATCAGTGTCGGCAAT
AGCCAGAGTGATGAGTACGCGATAGCAGATAAATATTACCGCATCTCCCGTGAAGTCATCCGTCATAATGATGGTCATGA
ATACCACATCACAGTGTTTGCCGACTTCACCGAATTAAAGCAGCGCAAGCAAGAACTCAAGCTTTCTCAGCAACAGGCTG
TCGACGCATTAAAGGCAAGAGAGTCATTTTTAGGGATTATCAGCCATGAGCTGAGAACGCCTCTCGCTGCAATGATAGGT
TTAATGGAGCTACTAAAACCTGAGCTTAAATCGACGCAAAATCAAGAGTTAATGAAAAATGCTCAGGCCTCTGCCGAGCG
CTTAAAAGCCTTAGTTAACGATATCTTAGACTTCTCCAAAATGGAGGCGGATCAGTTACTGCTCGATATTTATCAAGGCA
ATATCTTTGATGAACTCGGCTCTATGCTCAGAACACTCGAAGCCGGCGCTCGAGTCAAAGGGCTCGAGTTTATTGTCGAC
TGGCAACCCACAAGGCTCTGTCATGCAAAGCTCGATTGGCTCAGACTCAGCCAACTGGTCAACAACTTGGTGAGTAATGC
CATCAAGTTCACCCAACAGGGCTTAGTCAAGGTTTCGGTATCGAATACTGAGCAACAGCTGTACCTGTCGATTGAAGACA
GCGGCTGCGGCATGACGTCGGCGCAATTGCTCACGCTATTTCAACCCTTTGTACAAGGTGACCCAAGCATTAACAGAAAC
TATGGCGGCAGTGGATTAGGCATGTCTATCGTTGAGCATTTAGTGCAGCTAATGGGTGGAGAGATAAAGGTGCAGAGCCA
ACACGGTCAAGGTACTCAAGTTTGTGTGAGCCTACCCGCTGTATTTCACCCTTTAACACAGGCTATCGTGCCCGACGTCC
AAACTCAAAATGACAAGCTAACAGGCTGGCTCATGCAGTGGGGAGTGAACTTACATCAACAAGGTGCATGTGGACTCCCC
CTTGATGAGTTTAATCTGTCGAGCAATATCTACCCGGATCTATTGTTAAACGCGCTTTGTTTACCAAATGAGCTCGAGCA
GCACAATACGCCTACAAATCTAAAGTATGCAGGAAAAGTGTTAGTCGCCGATGACGATCCCATCAACCGTTTCCTGTTTC
AGAAACAACTTAAAAAGTTAGGCTTAGAGGTGGTGACAGTGAATGATGGCCTGGAGGCACTCGATTACTTAACTCATCAC
TTAGGAGCCATAACCTTGCTTATTACCGACTGCCATATGCCTAACCTAAATGGCTATGACTTAGTGCGCAAGCTTAGAGC
TAAAAGCGAGTTTAAAGCTTTACCTATAATAGGTTGCACCGCAGAAGACTCGCGCTTAGTCGCCGAAAAAGCCCAATGTG
TAGGCATGGATGAGCTCATCTATAAGCCCTACTCCTTCTATACACTTAGCACGCTATTAGGGCGCTATTGCCGATTGCAA
CCAACAGATGCTGGTCAGGATAAACTCGACTGGTTAAATGAATATGAGATAGAAGAGCAACTTGAGTTTTCAGCCGTTGT
TAGAGACTCGCTCATTGCAGATAAAGCACAGCTTGTAGAACAAGCGATACCACTTGCGGCAATCTGTCATCGTATCAAAG
GGGCCGCGAATGCACTCAATCTCCATGAGTTAGCCTCCCTCGCCTACGCCTGTGAAACCGTGTCGGCTGCTAATGCCTCG
TTGGCAACTAAGCGACTCGTCGATGAGATTGACTGCATCATCACAGCGATTAACAACTGGCTCAGTAAACAATATTTATG
A

Upstream 100 bases:

>100_bases
AGTTAGCGATAAATCGCCCTGAATTTGGCTAAACAAAAAATAGCCATAAAAATAAATTGGTCAAAAACTCGTTTTAGACT
ATTATGCGCAACCTTTTTCA

Downstream 100 bases:

>100_bases
TTATTTGATGCTCGCAGGCTTAGTGATTAAGCCCGCTCATCAACACTTTCGTTTTTTGGACAATACCCTTTATGCAATCT
TTTCAATCATTAAAAGTGCT

Product: Hpt sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 746; Mature: 745

Protein sequence:

>746_residues
MTAQQMAKPVVFLLLFTGLSSSLLAHSFELKPQEQLQPKTLVTAPTVTAGQESIALTSQLKYDETLSRFFQLILFTLISL
VLALNFLRSKKRKVFLSQALASGQASHDQMQWLMAVLDNFPGMVLISDANGKPMLANKAYNTCVQSGSATNPDSIISVGN
SQSDEYAIADKYYRISREVIRHNDGHEYHITVFADFTELKQRKQELKLSQQQAVDALKARESFLGIISHELRTPLAAMIG
LMELLKPELKSTQNQELMKNAQASAERLKALVNDILDFSKMEADQLLLDIYQGNIFDELGSMLRTLEAGARVKGLEFIVD
WQPTRLCHAKLDWLRLSQLVNNLVSNAIKFTQQGLVKVSVSNTEQQLYLSIEDSGCGMTSAQLLTLFQPFVQGDPSINRN
YGGSGLGMSIVEHLVQLMGGEIKVQSQHGQGTQVCVSLPAVFHPLTQAIVPDVQTQNDKLTGWLMQWGVNLHQQGACGLP
LDEFNLSSNIYPDLLLNALCLPNELEQHNTPTNLKYAGKVLVADDDPINRFLFQKQLKKLGLEVVTVNDGLEALDYLTHH
LGAITLLITDCHMPNLNGYDLVRKLRAKSEFKALPIIGCTAEDSRLVAEKAQCVGMDELIYKPYSFYTLSTLLGRYCRLQ
PTDAGQDKLDWLNEYEIEEQLEFSAVVRDSLIADKAQLVEQAIPLAAICHRIKGAANALNLHELASLAYACETVSAANAS
LATKRLVDEIDCIITAINNWLSKQYL

Sequences:

>Translated_746_residues
MTAQQMAKPVVFLLLFTGLSSSLLAHSFELKPQEQLQPKTLVTAPTVTAGQESIALTSQLKYDETLSRFFQLILFTLISL
VLALNFLRSKKRKVFLSQALASGQASHDQMQWLMAVLDNFPGMVLISDANGKPMLANKAYNTCVQSGSATNPDSIISVGN
SQSDEYAIADKYYRISREVIRHNDGHEYHITVFADFTELKQRKQELKLSQQQAVDALKARESFLGIISHELRTPLAAMIG
LMELLKPELKSTQNQELMKNAQASAERLKALVNDILDFSKMEADQLLLDIYQGNIFDELGSMLRTLEAGARVKGLEFIVD
WQPTRLCHAKLDWLRLSQLVNNLVSNAIKFTQQGLVKVSVSNTEQQLYLSIEDSGCGMTSAQLLTLFQPFVQGDPSINRN
YGGSGLGMSIVEHLVQLMGGEIKVQSQHGQGTQVCVSLPAVFHPLTQAIVPDVQTQNDKLTGWLMQWGVNLHQQGACGLP
LDEFNLSSNIYPDLLLNALCLPNELEQHNTPTNLKYAGKVLVADDDPINRFLFQKQLKKLGLEVVTVNDGLEALDYLTHH
LGAITLLITDCHMPNLNGYDLVRKLRAKSEFKALPIIGCTAEDSRLVAEKAQCVGMDELIYKPYSFYTLSTLLGRYCRLQ
PTDAGQDKLDWLNEYEIEEQLEFSAVVRDSLIADKAQLVEQAIPLAAICHRIKGAANALNLHELASLAYACETVSAANAS
LATKRLVDEIDCIITAINNWLSKQYL
>Mature_745_residues
TAQQMAKPVVFLLLFTGLSSSLLAHSFELKPQEQLQPKTLVTAPTVTAGQESIALTSQLKYDETLSRFFQLILFTLISLV
LALNFLRSKKRKVFLSQALASGQASHDQMQWLMAVLDNFPGMVLISDANGKPMLANKAYNTCVQSGSATNPDSIISVGNS
QSDEYAIADKYYRISREVIRHNDGHEYHITVFADFTELKQRKQELKLSQQQAVDALKARESFLGIISHELRTPLAAMIGL
MELLKPELKSTQNQELMKNAQASAERLKALVNDILDFSKMEADQLLLDIYQGNIFDELGSMLRTLEAGARVKGLEFIVDW
QPTRLCHAKLDWLRLSQLVNNLVSNAIKFTQQGLVKVSVSNTEQQLYLSIEDSGCGMTSAQLLTLFQPFVQGDPSINRNY
GGSGLGMSIVEHLVQLMGGEIKVQSQHGQGTQVCVSLPAVFHPLTQAIVPDVQTQNDKLTGWLMQWGVNLHQQGACGLPL
DEFNLSSNIYPDLLLNALCLPNELEQHNTPTNLKYAGKVLVADDDPINRFLFQKQLKKLGLEVVTVNDGLEALDYLTHHL
GAITLLITDCHMPNLNGYDLVRKLRAKSEFKALPIIGCTAEDSRLVAEKAQCVGMDELIYKPYSFYTLSTLLGRYCRLQP
TDAGQDKLDWLNEYEIEEQLEFSAVVRDSLIADKAQLVEQAIPLAAICHRIKGAANALNLHELASLAYACETVSAANASL
ATKRLVDEIDCIITAINNWLSKQYL

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=555, Percent_Identity=27.3873873873874, Blast_Score=165, Evalue=8e-42,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=40.1709401709402, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI145693157, Length=397, Percent_Identity=27.2040302267003, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI48994928, Length=550, Percent_Identity=26.9090909090909, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI87081816, Length=584, Percent_Identity=25.3424657534247, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=28.2608695652174, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=29.2035398230088, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=29.3103448275862, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787894, Length=276, Percent_Identity=25.3623188405797, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=27.6150627615063, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=275, Percent_Identity=26.5454545454545, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1789808, Length=233, Percent_Identity=26.1802575107296, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=273, Percent_Identity=23.4432234432234, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=25.6637168141593, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=26.9911504424779, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=246, Percent_Identity=26.0162601626016, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=25.9109311740891, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=73, Percent_Identity=39.7260273972603, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82843; Mature: 82712

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQQMAKPVVFLLLFTGLSSSLLAHSFELKPQEQLQPKTLVTAPTVTAGQESIALTSQL
CCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHCCCCEEEECCCCCCCCHHHHHHHHH
KYDETLSRFFQLILFTLISLVLALNFLRSKKRKVFLSQALASGQASHDQMQWLMAVLDNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
PGMVLISDANGKPMLANKAYNTCVQSGSATNPDSIISVGNSQSDEYAIADKYYRISREVI
CCEEEEECCCCCCEECHHHHHHHHHCCCCCCCHHHEECCCCCCCCCHHHHHHHHHHHHHH
RHNDGHEYHITVFADFTELKQRKQELKLSQQQAVDALKARESFLGIISHELRTPLAAMIG
HCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMELLKPELKSTQNQELMKNAQASAERLKALVNDILDFSKMEADQLLLDIYQGNIFDELG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SMLRTLEAGARVKGLEFIVDWQPTRLCHAKLDWLRLSQLVNNLVSNAIKFTQQGLVKVSV
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
SNTEQQLYLSIEDSGCGMTSAQLLTLFQPFVQGDPSINRNYGGSGLGMSIVEHLVQLMGG
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
EIKVQSQHGQGTQVCVSLPAVFHPLTQAIVPDVQTQNDKLTGWLMQWGVNLHQQGACGLP
CEEEECCCCCCCHHEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
LDEFNLSSNIYPDLLLNALCLPNELEQHNTPTNLKYAGKVLVADDDPINRFLFQKQLKKL
HHHCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCEECCEEEEECCCHHHHHHHHHHHHHC
GLEVVTVNDGLEALDYLTHHLGAITLLITDCHMPNLNGYDLVRKLRAKSEFKALPIIGCT
CCEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEECC
AEDSRLVAEKAQCVGMDELIYKPYSFYTLSTLLGRYCRLQPTDAGQDKLDWLNEYEIEEQ
CCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHH
LEFSAVVRDSLIADKAQLVEQAIPLAAICHRIKGAANALNLHELASLAYACETVSAANAS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCHH
LATKRLVDEIDCIITAINNWLSKQYL
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAQQMAKPVVFLLLFTGLSSSLLAHSFELKPQEQLQPKTLVTAPTVTAGQESIALTSQL
CHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHCCCCEEEECCCCCCCCHHHHHHHHH
KYDETLSRFFQLILFTLISLVLALNFLRSKKRKVFLSQALASGQASHDQMQWLMAVLDNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
PGMVLISDANGKPMLANKAYNTCVQSGSATNPDSIISVGNSQSDEYAIADKYYRISREVI
CCEEEEECCCCCCEECHHHHHHHHHCCCCCCCHHHEECCCCCCCCCHHHHHHHHHHHHHH
RHNDGHEYHITVFADFTELKQRKQELKLSQQQAVDALKARESFLGIISHELRTPLAAMIG
HCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMELLKPELKSTQNQELMKNAQASAERLKALVNDILDFSKMEADQLLLDIYQGNIFDELG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SMLRTLEAGARVKGLEFIVDWQPTRLCHAKLDWLRLSQLVNNLVSNAIKFTQQGLVKVSV
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
SNTEQQLYLSIEDSGCGMTSAQLLTLFQPFVQGDPSINRNYGGSGLGMSIVEHLVQLMGG
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
EIKVQSQHGQGTQVCVSLPAVFHPLTQAIVPDVQTQNDKLTGWLMQWGVNLHQQGACGLP
CEEEECCCCCCCHHEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
LDEFNLSSNIYPDLLLNALCLPNELEQHNTPTNLKYAGKVLVADDDPINRFLFQKQLKKL
HHHCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCEECCEEEEECCCHHHHHHHHHHHHHC
GLEVVTVNDGLEALDYLTHHLGAITLLITDCHMPNLNGYDLVRKLRAKSEFKALPIIGCT
CCEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEECC
AEDSRLVAEKAQCVGMDELIYKPYSFYTLSTLLGRYCRLQPTDAGQDKLDWLNEYEIEEQ
CCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHH
LEFSAVVRDSLIADKAQLVEQAIPLAAICHRIKGAANALNLHELASLAYACETVSAANAS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCHH
LATKRLVDEIDCIITAINNWLSKQYL
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA