Click here to switch to the map view.

The map label for this gene is ndh [H]

Identifier: 157960976

GI number: 157960976

Start: 1386127

End: 1387428

Strand: Reverse

Name: ndh [H]

Synonym: Spea_1148

Alternate gene names: 157960976

Gene position: 1387428-1386127 (Counterclockwise)

Preceding gene: 157960977

Following gene: 157960975

Centisome position: 26.81

GC content: 45.93

Gene sequence:

>1302_bases
ATGCATGAAATGCCTAATATTGTCATCGTAGGTGGCGGCGCTGGTGGAATGGAGATCGCAACCAAACTCGGTCACCAACT
CGGGCGTAAAGGCAAAGCCAGAGTCACACTGATTGACTGTGCCGAAAGCCATGTTTGGAAACCTCTTCTGCATGAAGTTG
CCACCGGCGCATTAGATATTGGTATAGATGCAATTAGCTATCGTGGTCACGCAGCCAATCATGGTTATCACTTTCAACAA
GGGGCTATGACAGATCTTGATAGAGAAGCTAAGCAGGTAATTCTCGCGCCAATTAACGATGACAAAGGTCGTGAATTACT
ACCAGCGCGCCGTATCGATTACGACTATTTAGTCATTGCCATTGGCAGTATCGCCAATGACTTTAATATTACTGGCGTTC
GCGATCATTGCGTATTTTTAGATAGCACCGAACAAGCAATGGAAATTCGCACCATGCTGCTTAATAAGTTCATGCGCTAC
GCCAGCCACCACCAATTAGACGACAAAATCAAAATTGCCGTTGTCGGCGCTGGTGCAACCGGCGTTGAAATGTCAGCAGA
GATGCACCATGCGGTGGAACAGCTACGCGGCTTCGGTTATAAAATCGATAGTAGCTTATTGGAAATAACTCTTATTGAAG
CCGATGAGCGCATTTTACCAAAAGTTGAAAAAGAAGAGATCTCAGCCTCTGTCGCCAAAGAGTTAACTTCTATCGGCGTA
AAAGTGATGACCAACACCCGCATCAACCAAGTAACAGAAGAAGGTCTACACACTTCTGAAGGCGAATTTATTCAATCTGA
TATGGTGATCTGGTCAACCGGCGTTAAAGCCCCAGATTTTCTAAAAGAGATCGGCGGACTTGAAAGTAACCATATCAACC
AAGTCATGGTGCAGCAAAACATGCAAACCACGCGAGACCCATCGATTTTTGCTATCGGTGACTGCGCAGCATGTCCTCAA
GAAGATGGCAGCTGGGTACCTCCTCGTGGTCAATCGGCACGTCAAATGGCGTTGATGACAGCTGACAATATTAAGTTACT
TTTGGCCGGAAAAGCCGCGTCAAATAACTATGTTTATAAAGACCTAGGTGCCTTGGTTAACCTATCTAAGTTCCACACAG
TGGGTAATTTGATGTCCTTTATCGGTGGCGGCGTCATGGTTGAGGGTAAGATTGCTCGCTTCGTCTACACCTCTTTATAC
CGCAGACACTTGATTGAGCTTCACGGCCCAATTAAAGGCACCCTGTTAATGTTTGCCAAAGGCATTAGCCGAATTGTACA
CCCACATCTGAAACTGCACTAA

Upstream 100 bases:

>100_bases
CCAGGCTTAATTAACTGCTATTTAAATAGTTACACCTTGCTATTACTCAAGTTAACCCTATATTTATTTTACAGTTTTCT
GATTAAGGATTATAAAACTC

Downstream 100 bases:

>100_bases
TTAGCTTGCTGAATGTTGCTGGTATTTTGGTATAGCGCCAGCAACATTTTGTTTGCCTACCTGAAAGGGAAATCAAACTT
CGTTTGATAAAGATCGTGAG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MHEMPNIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHVWKPLLHEVATGALDIGIDAISYRGHAANHGYHFQQ
GAMTDLDREAKQVILAPINDDKGRELLPARRIDYDYLVIAIGSIANDFNITGVRDHCVFLDSTEQAMEIRTMLLNKFMRY
ASHHQLDDKIKIAVVGAGATGVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
KVMTNTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQNMQTTRDPSIFAIGDCAACPQ
EDGSWVPPRGQSARQMALMTADNIKLLLAGKAASNNYVYKDLGALVNLSKFHTVGNLMSFIGGGVMVEGKIARFVYTSLY
RRHLIELHGPIKGTLLMFAKGISRIVHPHLKLH

Sequences:

>Translated_433_residues
MHEMPNIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHVWKPLLHEVATGALDIGIDAISYRGHAANHGYHFQQ
GAMTDLDREAKQVILAPINDDKGRELLPARRIDYDYLVIAIGSIANDFNITGVRDHCVFLDSTEQAMEIRTMLLNKFMRY
ASHHQLDDKIKIAVVGAGATGVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
KVMTNTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQNMQTTRDPSIFAIGDCAACPQ
EDGSWVPPRGQSARQMALMTADNIKLLLAGKAASNNYVYKDLGALVNLSKFHTVGNLMSFIGGGVMVEGKIARFVYTSLY
RRHLIELHGPIKGTLLMFAKGISRIVHPHLKLH
>Mature_433_residues
MHEMPNIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHVWKPLLHEVATGALDIGIDAISYRGHAANHGYHFQQ
GAMTDLDREAKQVILAPINDDKGRELLPARRIDYDYLVIAIGSIANDFNITGVRDHCVFLDSTEQAMEIRTMLLNKFMRY
ASHHQLDDKIKIAVVGAGATGVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
KVMTNTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQNMQTTRDPSIFAIGDCAACPQ
EDGSWVPPRGQSARQMALMTADNIKLLLAGKAASNNYVYKDLGALVNLSKFHTVGNLMSFIGGGVMVEGKIARFVYTSLY
RRHLIELHGPIKGTLLMFAKGISRIVHPHLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=432, Percent_Identity=54.3981481481482, Blast_Score=482, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6320118, Length=329, Percent_Identity=27.6595744680851, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6323515, Length=452, Percent_Identity=26.3274336283186, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323794, Length=330, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47550; Mature: 47550

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMPNIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHVWKPLLHEVATGALDI
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHC
GIDAISYRGHAANHGYHFQQGAMTDLDREAKQVILAPINDDKGRELLPARRIDYDYLVIA
CCEEEECCCCCCCCCEEECCCCCCHHHHHCCEEEEEECCCCCCCCCCCHHHCCCCEEEEE
IGSIANDFNITGVRDHCVFLDSTEQAMEIRTMLLNKFMRYASHHQLDDKIKIAVVGAGAT
EECCCCCCCCCEEECEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
GVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
CCCHHHHHHHHHHHHHCCCEEECCCEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHCCE
KVMTNTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQN
EEEECCHHHHHHHHCCCCCCCCEECCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHC
MQTTRDPSIFAIGDCAACPQEDGSWVPPRGQSARQMALMTADNIKLLLAGKAASNNYVYK
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCHH
DLGALVNLSKFHTVGNLMSFIGGGVMVEGKIARFVYTSLYRRHLIELHGPIKGTLLMFAK
HHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GISRIVHPHLKLH
HHHHHHCCCCCCC
>Mature Secondary Structure
MHEMPNIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHVWKPLLHEVATGALDI
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHC
GIDAISYRGHAANHGYHFQQGAMTDLDREAKQVILAPINDDKGRELLPARRIDYDYLVIA
CCEEEECCCCCCCCCEEECCCCCCHHHHHCCEEEEEECCCCCCCCCCCHHHCCCCEEEEE
IGSIANDFNITGVRDHCVFLDSTEQAMEIRTMLLNKFMRYASHHQLDDKIKIAVVGAGAT
EECCCCCCCCCEEECEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
GVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
CCCHHHHHHHHHHHHHCCCEEECCCEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHCCE
KVMTNTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQN
EEEECCHHHHHHHHCCCCCCCCEECCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHC
MQTTRDPSIFAIGDCAACPQEDGSWVPPRGQSARQMALMTADNIKLLLAGKAASNNYVYK
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCHH
DLGALVNLSKFHTVGNLMSFIGGGVMVEGKIARFVYTSLYRRHLIELHGPIKGTLLMFAK
HHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GISRIVHPHLKLH
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]