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The map label for this gene is obgE [H]

Identifier: 157960682

GI number: 157960682

Start: 1052958

End: 1054121

Strand: Direct

Name: obgE [H]

Synonym: Spea_0854

Alternate gene names: 157960682

Gene position: 1052958-1054121 (Clockwise)

Preceding gene: 157960681

Following gene: 157960683

Centisome position: 20.35

GC content: 44.42

Gene sequence:

>1164_bases
ATGAAGTTTGTCGATGAAGCTATTATCCGTGTAGAAGCCGGAAATGGTGGCAGTGGTTGCGTTAGCTTTAGACGCGAAAA
ATATGTTCCTGATGGTGGTCCTGACGGTGGTGATGGTGGTGACGGCGGTAGTGTATATCTACAAGCCGATGAAAACTTGA
ACACATTGATCACTTATCAGTTTGAACGCTTCCATATTGCCGAGCGCGGTAAGAATGGTCGTGGGCGTGATTGTACTGGT
CACGGCGGTGAAGACTTGATCCTTAAAGTGCCGGTTGGTACTCGCGCTATCGATAACGATACTGAAGAGTCACTTGGTGA
CTTAACCACTCACGGGCAAAAATTGCTTGTGGCTAAAGGTGGTTTCCATGGTCTAGGTAATACTCGTTTCAAGAGTAGTA
CTAACCGTGCGCCAAGACAGAAAACCTTAGGTACTGACGGTGAAGTGCGTAGCTTAAAGCTAGAGCTATTACTGTTAGCC
GATGTAGGCCTACTTGGTATGCCGAATGCGGGTAAGTCAACCTTCATTCGCTCTGTATCGAAGGCTAAGCCAAAGGTTGC
CGATTATCCATTTACCACTTTGGTCCCTAACCTAGGTGTTGTTAATCCTAGACCAGGTCAGAGCTTTGTAATTGCGGATA
TTCCAGGGCTTATCGAAGGCGCTGCTGATGGTGCAGGTCTTGGTGTACAGTTCCTAAAGCATTTAGAACGTTGCCGTGTG
TTGTTACACATTTTGGACGTTGAGCCTATCGATGGTAGCGATCCAGTTGAAGCTGCTCGTGCAATCGTTGCTGAGCTTGA
AAAGCACTCTCCTAAGCTTGCGGGTAAGCCACGTTGGTTAGTAATCAACAAAGCTGACTTGATGTTGCCAGAAGAGCTAC
AAGAACGTATTGACCGTATCGTTAAAGAGTTAGAGTGGGAAGGTGATATTTACACTATTTCTGCTTATAACCGTGAAGGT
ACTGCTGAGTTAGCCCTTAAGTTATTAGACTTTATCGATTCACTTCCTCCTGAAGAAGAAGTTGATGCTGATGCTGAAGT
CGAATTTAAGTGGGATAACTATCATCAGAATGCAAATGATTCTATTAACGAAGATTTTAACGACGATTTCGATGATGATT
TCGACGAAGATGATTACGATGTAGAGATTATCTACCAAAGATAA

Upstream 100 bases:

>100_bases
ATTGGTGGGGCTTTGTTTTTTCAAAATTAAGTAAATTGTGTTTTGGCGACTAGAATCGTTAAGAGTATAATTCTTTCATT
CTGTGGTGCCAGGAGTTGGT

Downstream 100 bases:

>100_bases
TTATTTGCAGAAAGGGAAGTTGAGAAAAGGTGTACGCTACAACGCAAAATGACATTACTCGTCAAGTCGTTAGGGTTGCT
CAACTTCTTTTAGCTTATGG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITYQFERFHIAERGKNGRGRDCTG
HGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRSVSKAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
LLHILDVEPIDGSDPVEAARAIVAELEKHSPKLAGKPRWLVINKADLMLPEELQERIDRIVKELEWEGDIYTISAYNREG
TAELALKLLDFIDSLPPEEEVDADAEVEFKWDNYHQNANDSINEDFNDDFDDDFDEDDYDVEIIYQR

Sequences:

>Translated_387_residues
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITYQFERFHIAERGKNGRGRDCTG
HGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRSVSKAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
LLHILDVEPIDGSDPVEAARAIVAELEKHSPKLAGKPRWLVINKADLMLPEELQERIDRIVKELEWEGDIYTISAYNREG
TAELALKLLDFIDSLPPEEEVDADAEVEFKWDNYHQNANDSINEDFNDDFDDDFDEDDYDVEIIYQR
>Mature_387_residues
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITYQFERFHIAERGKNGRGRDCTG
HGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRSVSKAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
LLHILDVEPIDGSDPVEAARAIVAELEKHSPKLAGKPRWLVINKADLMLPEELQERIDRIVKELEWEGDIYTISAYNREG
TAELALKLLDFIDSLPPEEEVDADAEVEFKWDNYHQNANDSINEDFNDDFDDDFDEDDYDVEIIYQR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=339, Percent_Identity=37.7581120943953, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI111955139, Length=323, Percent_Identity=33.7461300309598, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI111955063, Length=145, Percent_Identity=39.3103448275862, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=36.4406779661017, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=33.8842975206612, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI58761500, Length=138, Percent_Identity=30.4347826086957, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=364, Percent_Identity=65.3846153846154, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=36, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790615, Length=173, Percent_Identity=27.1676300578035, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=37.962962962963, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=323, Percent_Identity=28.1733746130031, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.9375, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=34.7457627118644, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=202, Percent_Identity=36.1386138613861, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=35.15625, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129375, Length=303, Percent_Identity=39.9339933993399, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24585318, Length=288, Percent_Identity=37.5, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17981711, Length=118, Percent_Identity=33.8983050847458, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42519; Mature: 42519

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITYQ
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEE
FERFHIAERGKNGRGRDCTGHGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKG
EHEEEHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLADVGLLGMPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEEEEEECCCEECCCCCCHHHHHHHHH
KAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
LLHILDVEPIDGSDPVEAARAIVAELEKHSPKLAGKPRWLVINKADLMLPEELQERIDRI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
VKELEWEGDIYTISAYNREGTAELALKLLDFIDSLPPEEEVDADAEVEFKWDNYHQNAND
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCCCCCC
SINEDFNDDFDDDFDEDDYDVEIIYQR
CCCCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITYQ
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEE
FERFHIAERGKNGRGRDCTGHGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKG
EHEEEHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLADVGLLGMPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEEEEEECCCEECCCCCCHHHHHHHHH
KAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
LLHILDVEPIDGSDPVEAARAIVAELEKHSPKLAGKPRWLVINKADLMLPEELQERIDRI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
VKELEWEGDIYTISAYNREGTAELALKLLDFIDSLPPEEEVDADAEVEFKWDNYHQNAND
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCCCCCC
SINEDFNDDFDDDFDEDDYDVEIIYQR
CCCCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA