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The map label for this gene is uspE [H]

Identifier: 157960447

GI number: 157960447

Start: 762721

End: 763605

Strand: Direct

Name: uspE [H]

Synonym: Spea_0618

Alternate gene names: 157960447

Gene position: 762721-763605 (Clockwise)

Preceding gene: 157960446

Following gene: 157960457

Centisome position: 14.74

GC content: 45.88

Gene sequence:

>885_bases
ATGGACAAAGTATTTATTATTTCCCAAAGAGAAGAGGCTCATGTCGATGCTGTATCGGCGGGAGTCGAACTTGCCAGAGT
ATTAGGTAAACGTGCCGAAGTATTTGCTTATAGTTTTGAATATTTTGGCAATGCCGAGTACTACAATCCTAAGTTTGTTG
CGGTTGCACAAAAGCATGTAATGAAGCAGCGAATGGCAAAGATCGAGTTGGAGCTAGAGAGTATTCATGCCGAAGATACG
CCAACCCACAGCGTGTGGAGTAAAGATCTCTATGAGCATGCTTGTCATCACTCAGACCGTCATGGTTTCGATCTTATGGT
TAAAGCGGTACACCATGCAGAGCACTATTTACCTGTAGATTGGAACCTTATTCGTCATACCCGAGTGCCATTAATGCTGC
TGACCGATAATCCGCTGCTGAAGAATAATACCGTGATGATGGCGCTCGATCTGGATAGCAAAAAAACCTTAAAGCAGCAG
TTGAATCAAGCCGTGATTCGTCAGGCAACCACCTTGGCAAAAGCGACAGGATGCGAGTTACATCTTGCATTTGTGATCCG
ATTACCTCAAGTGATCCATGATATGGAGATAGTCGATACTCATGCCATGGTCAGGGAGGCTAGGGAAAAACATCAAGCTT
TGTTTGATGAGCTCAATATCGATCCTAAGTGCCTGCATATTACGGTGGGGGAGCCGGATCTGTGTATCTACCAGTTAGCT
TGTAAGCATAAGGTTCGCTACTTAGTACTGGGAGCTGTGCAGCGTCAAGGCCTGTACGCTTTTGTGGTGGGTAATATGGC
TGAATCAATACTAAGCCGCATTCGCAGCAATGTGTTGGTTGTACCTGCCCGCGAGGGGGTATTGCAGCCTCTAGGAGATA
GTTGA

Upstream 100 bases:

>100_bases
AATATTTAGTTTGATCCGGATCATTGTTGGTCTCGGTTTAGCTTCATTAAATAGTAAGTTTAGCTAAGCTAATATTAGGT
AGTTGTTAGTGGAGATAGCT

Downstream 100 bases:

>100_bases
TAGGAGAGAGTTTACACCCATGCGCGGCTTAGAAAGCCGCGGGCGCTGTTTGATGCTGGGTGCGACGCAGCGTCAAGGCG
TTTACGCCTTTGTGGTCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDKVFIISQREEAHVDAVSAGVELARVLGKRAEVFAYSFEYFGNAEYYNPKFVAVAQKHVMKQRMAKIELELESIHAEDT
PTHSVWSKDLYEHACHHSDRHGFDLMVKAVHHAEHYLPVDWNLIRHTRVPLMLLTDNPLLKNNTVMMALDLDSKKTLKQQ
LNQAVIRQATTLAKATGCELHLAFVIRLPQVIHDMEIVDTHAMVREAREKHQALFDELNIDPKCLHITVGEPDLCIYQLA
CKHKVRYLVLGAVQRQGLYAFVVGNMAESILSRIRSNVLVVPAREGVLQPLGDS

Sequences:

>Translated_294_residues
MDKVFIISQREEAHVDAVSAGVELARVLGKRAEVFAYSFEYFGNAEYYNPKFVAVAQKHVMKQRMAKIELELESIHAEDT
PTHSVWSKDLYEHACHHSDRHGFDLMVKAVHHAEHYLPVDWNLIRHTRVPLMLLTDNPLLKNNTVMMALDLDSKKTLKQQ
LNQAVIRQATTLAKATGCELHLAFVIRLPQVIHDMEIVDTHAMVREAREKHQALFDELNIDPKCLHITVGEPDLCIYQLA
CKHKVRYLVLGAVQRQGLYAFVVGNMAESILSRIRSNVLVVPAREGVLQPLGDS
>Mature_294_residues
MDKVFIISQREEAHVDAVSAGVELARVLGKRAEVFAYSFEYFGNAEYYNPKFVAVAQKHVMKQRMAKIELELESIHAEDT
PTHSVWSKDLYEHACHHSDRHGFDLMVKAVHHAEHYLPVDWNLIRHTRVPLMLLTDNPLLKNNTVMMALDLDSKKTLKQQ
LNQAVIRQATTLAKATGCELHLAFVIRLPQVIHDMEIVDTHAMVREAREKHQALFDELNIDPKCLHITVGEPDLCIYQLA
CKHKVRYLVLGAVQRQGLYAFVVGNMAESILSRIRSNVLVVPAREGVLQPLGDS

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1787594, Length=281, Percent_Identity=24.1992882562278, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 33427; Mature: 33427

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVFIISQREEAHVDAVSAGVELARVLGKRAEVFAYSFEYFGNAEYYNPKFVAVAQKHV
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHEEEEEHHHCCCCCCCCCCHHHHHHHHH
MKQRMAKIELELESIHAEDTPTHSVWSKDLYEHACHHSDRHGFDLMVKAVHHAEHYLPVD
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
WNLIRHTRVPLMLLTDNPLLKNNTVMMALDLDSKKTLKQQLNQAVIRQATTLAKATGCEL
CHHHHHCCCCEEEEECCCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
HLAFVIRLPQVIHDMEIVDTHAMVREAREKHQALFDELNIDPKCLHITVGEPDLCIYQLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHH
CKHKVRYLVLGAVQRQGLYAFVVGNMAESILSRIRSNVLVVPAREGVLQPLGDS
HHHHHHHHEEEHHHHCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDKVFIISQREEAHVDAVSAGVELARVLGKRAEVFAYSFEYFGNAEYYNPKFVAVAQKHV
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHEEEEEHHHCCCCCCCCCCHHHHHHHHH
MKQRMAKIELELESIHAEDTPTHSVWSKDLYEHACHHSDRHGFDLMVKAVHHAEHYLPVD
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
WNLIRHTRVPLMLLTDNPLLKNNTVMMALDLDSKKTLKQQLNQAVIRQATTLAKATGCEL
CHHHHHCCCCEEEEECCCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
HLAFVIRLPQVIHDMEIVDTHAMVREAREKHQALFDELNIDPKCLHITVGEPDLCIYQLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHH
CKHKVRYLVLGAVQRQGLYAFVVGNMAESILSRIRSNVLVVPAREGVLQPLGDS
HHHHHHHHEEEHHHHCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]