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The map label for this gene is kefC [H]

Identifier: 157960411

GI number: 157960411

Start: 714205

End: 715863

Strand: Reverse

Name: kefC [H]

Synonym: Spea_0582

Alternate gene names: 157960411

Gene position: 715863-714205 (Counterclockwise)

Preceding gene: 157960412

Following gene: 157960410

Centisome position: 13.83

GC content: 47.44

Gene sequence:

>1659_bases
ATGGAACCCGCCATACTCATTATCACCTTAGCCTGCGGCATGTTAGTTAGCCGTGTGGGACTTCCCCCTCTAATTGGCTA
TCTTGTTGCGGGATTTGTGCTGTTTCTGTTTGGTATCGAAGAGTCCAGTTTACCCATGCTGGAGCAACTGGCTAACCTAG
GTGTTACTCTGCTGTTATTTGCCATCGGCCTAAAGTTAGATCTGCGCAGCCTGTTTAAAGCCGAGGTGTGGGCAGGATCA
AGCCTACATTTATTAGGCTCTATGCTGTTCTTTATTCCGCTATTAAAGCTGCTGGGGTTATTAGGGCTTGAGCAACTCAC
CGGATTAGAGCTTGAGCAATTAGCCCTACTCGCCTTCGCACTGAGCTTTTCCAGTACCATTTTTGCGGTCAAAATACTCG
AAGATAAGGGTGACATGCAGACGCTTTATGGCCGCGTCGCGATCGGTATCTTAATCATGCAAGATATCTTTGCGGTCGCC
TTTCTCACCATCTCTAAAGGCGATATCCCCTCCTACTGGGCATTAGGACTACTGTTACTACCGCTGGCAAAGCCACTCAT
ATACAAGGCATTCGACCGTGTTGGCCACGGTGAGCTATTAGTGCTATTTGGCTTAGTCATGGCGCTAGTCATGGGCGCTG
GGCTATTTGAACTTGTTGGCCTAAAACCAGATCTTGGCGCACTCGTCATAGGTATTTTACTGGCGGGTCACCCTAAATCA
TCGGAGCTGGCAAAATCACTGTTTTACTTCAAAGAACTGTTCTTAGTCGCCTTCTTCTTAACCGTTGGTCTTAACGGCTT
ACCGACCTTCTCCGATATCGGTTTGGCTGCGATTTTAGTACTTATTGTACCGATTAAAGTCACCCTATTTTTGTACTTAT
TAACCCACTTTAAGCTACGTTCTCGTACCGCACTAATGAGCTCATTTACCTTAGGTAACTACAGCGAATTTGGCCTAATT
GTGGCTGCAGTTGCAACCTCAAAGGGTTGGCTGCCACCACAGTGGATGGTGATCCTTGCTGTTGCGCTCAGCTTTAGCTT
CTTGTTTGCCGCGCCGCTTAATACCGCTTCTAGCCGTTTATATCAGAAGTTTCAAAGCAAACTTAAACGCTTAGAAAAGC
ACCCTCTTCACCCTGAAGATAGACCGATCCCCGTCGGCAACCCACGCTTTCTTATCTTAGGTATGGGGCGTATCGGTTCT
GGTGCTTATGATGAACTCAGGGCTCGTTATGATGGTGAGATCTTAGGCGTCGAGCATAAGCAAGAACTGGTCGACTTTCA
TATTTCACAGGGCAGAAATGTAGTACAAGGTGATGCCTCGGATACCGACTTTTGGGAGAAGCTCGATAGAGCCCCCTACC
TAGAGCTCGTACTACTGACCATGCCTCATCACGTGGGTAACCAGTTTGCCGTCGAGCAATTACAACTTCTCGACTACCAA
GGTAAATTGAGTGCTATCGTCAAGTACAAAGAAGATGCACAGTCACTGAGCGAGTCTGGGGTGCACAGTGTTTATAATCT
CTATGAAGCTGCGGGAGCGGGTTTTGTTGAGCATTTGGTCAAAGAATTGCTGACTCCTAGTGGCGCTGCGCCAGATAACC
CCCACGCGATAAACCGTAAAAATGAGGCGAATGCATTAGAAACTGAACAAAAGGGCTAA

Upstream 100 bases:

>100_bases
ACTTATTCACATTTTTCAGCTCAACTTCATAAATTTCTTATACAATGGTGCATCATTATACCCAAAGTACTTGGATGTAA
ATCAACCATAAAGGAGCATC

Downstream 100 bases:

>100_bases
TTGTATACATTATCCCTGTTATAGCGTATGTTATTTGTTAACGAGTATTTAATGACCGATAACATACAATGCCAAACAAT
AATAAAAACTCTACTCTGGC

Product: sodium/hydrogen exchanger

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLFAIGLKLDLRSLFKAEVWAGS
SLHLLGSMLFFIPLLKLLGLLGLEQLTGLELEQLALLAFALSFSSTIFAVKILEDKGDMQTLYGRVAIGILIMQDIFAVA
FLTISKGDIPSYWALGLLLLPLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVTLFLYLLTHFKLRSRTALMSSFTLGNYSEFGLI
VAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASSRLYQKFQSKLKRLEKHPLHPEDRPIPVGNPRFLILGMGRIGS
GAYDELRARYDGEILGVEHKQELVDFHISQGRNVVQGDASDTDFWEKLDRAPYLELVLLTMPHHVGNQFAVEQLQLLDYQ
GKLSAIVKYKEDAQSLSESGVHSVYNLYEAAGAGFVEHLVKELLTPSGAAPDNPHAINRKNEANALETEQKG

Sequences:

>Translated_552_residues
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLFAIGLKLDLRSLFKAEVWAGS
SLHLLGSMLFFIPLLKLLGLLGLEQLTGLELEQLALLAFALSFSSTIFAVKILEDKGDMQTLYGRVAIGILIMQDIFAVA
FLTISKGDIPSYWALGLLLLPLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVTLFLYLLTHFKLRSRTALMSSFTLGNYSEFGLI
VAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASSRLYQKFQSKLKRLEKHPLHPEDRPIPVGNPRFLILGMGRIGS
GAYDELRARYDGEILGVEHKQELVDFHISQGRNVVQGDASDTDFWEKLDRAPYLELVLLTMPHHVGNQFAVEQLQLLDYQ
GKLSAIVKYKEDAQSLSESGVHSVYNLYEAAGAGFVEHLVKELLTPSGAAPDNPHAINRKNEANALETEQKG
>Mature_552_residues
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLFAIGLKLDLRSLFKAEVWAGS
SLHLLGSMLFFIPLLKLLGLLGLEQLTGLELEQLALLAFALSFSSTIFAVKILEDKGDMQTLYGRVAIGILIMQDIFAVA
FLTISKGDIPSYWALGLLLLPLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVTLFLYLLTHFKLRSRTALMSSFTLGNYSEFGLI
VAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASSRLYQKFQSKLKRLEKHPLHPEDRPIPVGNPRFLILGMGRIGS
GAYDELRARYDGEILGVEHKQELVDFHISQGRNVVQGDASDTDFWEKLDRAPYLELVLLTMPHHVGNQFAVEQLQLLDYQ
GKLSAIVKYKEDAQSLSESGVHSVYNLYEAAGAGFVEHLVKELLTPSGAAPDNPHAINRKNEANALETEQKG

Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786232, Length=468, Percent_Identity=27.1367521367521, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786685, Length=539, Percent_Identity=26.3450834879406, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789749, Length=448, Percent_Identity=25.2232142857143, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 60359; Mature: 60359

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLF
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHH
AIGLKLDLRSLFKAEVWAGSSLHLLGSMLFFIPLLKLLGLLGLEQLTGLELEQLALLAFA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHH
LSFSSTIFAVKILEDKGDMQTLYGRVAIGILIMQDIFAVAFLTISKGDIPSYWALGLLLL
HHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
PLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCH
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVTLFLYLLTHFKLR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRTALMSSFTLGNYSEFGLIVAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASSRL
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YQKFQSKLKRLEKHPLHPEDRPIPVGNPRFLILGMGRIGSGAYDELRARYDGEILGVEHK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEECCHHH
QELVDFHISQGRNVVQGDASDTDFWEKLDRAPYLELVLLTMPHHVGNQFAVEQLQLLDYQ
HHHHHHHHHCCCCEEECCCCCCHHHHHHCCCCHHHHHHHHCCHHCCCHHHHHHHHHHCCC
GKLSAIVKYKEDAQSLSESGVHSVYNLYEAAGAGFVEHLVKELLTPSGAAPDNPHAINRK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
NEANALETEQKG
CCCCCCCCCCCC
>Mature Secondary Structure
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLF
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHH
AIGLKLDLRSLFKAEVWAGSSLHLLGSMLFFIPLLKLLGLLGLEQLTGLELEQLALLAFA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHH
LSFSSTIFAVKILEDKGDMQTLYGRVAIGILIMQDIFAVAFLTISKGDIPSYWALGLLLL
HHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
PLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCH
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVTLFLYLLTHFKLR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRTALMSSFTLGNYSEFGLIVAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASSRL
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YQKFQSKLKRLEKHPLHPEDRPIPVGNPRFLILGMGRIGSGAYDELRARYDGEILGVEHK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEECCHHH
QELVDFHISQGRNVVQGDASDTDFWEKLDRAPYLELVLLTMPHHVGNQFAVEQLQLLDYQ
HHHHHHHHHCCCCEEECCCCCCHHHHHHCCCCHHHHHHHHCCHHCCCHHHHHHHHHHCCC
GKLSAIVKYKEDAQSLSESGVHSVYNLYEAAGAGFVEHLVKELLTPSGAAPDNPHAINRK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
NEANALETEQKG
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA